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Items: 1 to 50 of 120

1.

Arylacetamide Deacetylase Enzyme: Presence and Interindividual Variability in Human Lungs.

Gabriele M, Puccini P, Lucchi M, Aprile V, Gervasi PG, Longo V.

Drug Metab Dispos. 2019 Sep;47(9):961-965. doi: 10.1124/dmd.119.087031. Epub 2019 Jun 24.

PMID:
31235486
2.

Presence and inter-individual variability of carboxylesterases (CES1 and CES2) in human lung.

Gabriele M, Puccini P, Lucchi M, Vizziello A, Gervasi PG, Longo V.

Biochem Pharmacol. 2018 Apr;150:64-71. doi: 10.1016/j.bcp.2018.01.028. Epub 2018 Feb 3.

PMID:
29407485
3.

Screening and identification of major phytochemical compounds in seeds, sprouts and leaves of Tuscan black kale Brassica oleracea (L.) ssp acephala (DC) var. sabellica L.

Giorgetti L, Giorgi G, Cherubini E, Gervasi PG, Della Croce CM, Longo V, Bellani L.

Nat Prod Res. 2018 Jul;32(14):1617-1626. doi: 10.1080/14786419.2017.1392953. Epub 2017 Oct 23.

PMID:
29058468
4.

Effect of HFD/STZ on expression of genes involved in lipid, cholesterol and glucose metabolism in rats.

Pozzo L, Vornoli A, Coppola I, Croce CM, Giorgetti L, Gervasi PG, Longo V.

Life Sci. 2016 Dec 1;166:149-156. doi: 10.1016/j.lfs.2016.09.022. Epub 2016 Sep 28.

PMID:
27693527
5.

Modulation of lipid homeostasis in response to continuous or intermittent high-fat diet in pigs.

Puccinelli E, Gervasi PG, Trivella MG, Vornoli A, Viglione F, Pelosi G, Parodi O, Sampietro T, Puntoni M.

Animal. 2015 Jun;9(6):1000-7. doi: 10.1017/S1751731114003292. Epub 2015 Feb 4.

PMID:
25649276
6.

Drug metabolism enzymes in a steatotic model of rat treated with a high fat diet and a low dose of streptozotocin.

Vornoli A, Pozzo L, Della Croce CM, Gervasi PG, Longo V.

Food Chem Toxicol. 2014 Aug;70:54-60. doi: 10.1016/j.fct.2014.04.042. Epub 2014 May 9.

PMID:
24815820
7.

Modulation of cytochrome P450 enzymes in response to continuous or intermittent high-fat diet in pigs.

Puccinelli E, Gervasi PG, Pelosi G, Puntoni M, Longo V.

Xenobiotica. 2013 Aug;43(8):686-98. doi: 10.3109/00498254.2012.756558. Epub 2013 Jan 29.

PMID:
23360109
8.

Expression and inducibility of CYP1A1, 1A2, 1B1 by β-naphthoflavone and CYP2B22, CYP3As by rifampicin in heart regions and coronary arteries of pig.

Messina A, Puccinelli E, Gervasi PG, Longo V.

Res Vet Sci. 2013 Feb;94(1):77-83. doi: 10.1016/j.rvsc.2012.07.015. Epub 2012 Aug 11.

PMID:
22889553
9.

Structural influence of isothiocyanates on expression of cytochrome P450, phase II enzymes, and activation of Nrf2 in primary rat hepatocytes.

La Marca M, Beffy P, Della Croce C, Gervasi PG, Iori R, Puccinelli E, Longo V.

Food Chem Toxicol. 2012 Aug;50(8):2822-30. doi: 10.1016/j.fct.2012.05.044. Epub 2012 Jun 1.

PMID:
22664424
10.

Cloning and tissues expression of the pig CYP1B1 and CYP2J34.

Messina A, Siniscalco A, Puccinelli E, Gervasi PG, Longo V.

Res Vet Sci. 2012 Jun;92(3):438-43. doi: 10.1016/j.rvsc.2011.04.012. Epub 2011 May 7.

PMID:
21550618
11.

Xenobiotic metabolizing cytochrome P450 in pig, a promising animal model.

Puccinelli E, Gervasi PG, Longo V.

Curr Drug Metab. 2011 Jul;12(6):507-25. Review.

PMID:
21476973
12.

Expression and characterization of two new alkane-inducible cytochrome P450s from Trichoderma harzianum.

Del Carratore R, Gervasi PG, Contini MP, Beffy P, Maserti BE, Giovannetti G, Brondolo A, Longo V.

Biotechnol Lett. 2011 Jun;33(6):1201-6. doi: 10.1007/s10529-011-0557-0. Epub 2011 Feb 16. Erratum in: Biotechnol Lett. 2011 Jun;33(6):1207. Carratore, R Del [corrected to Del Carratore, R].

PMID:
21327702
13.

Cisplatin induced toxicity in rat tissues: the protective effect of Lisosan G.

Longo V, Gervasi PG, Lubrano V.

Food Chem Toxicol. 2011 Jan;49(1):233-7. doi: 10.1016/j.fct.2010.10.021. Epub 2010 Oct 29.

PMID:
20971153
14.

Expression and inducibility by phenobarbital of CYP2C33, CYP2C42, CYP2C49, CYP2B22, and CYP3As in porcine liver, kidney, small intestine, and nasal tissues.

Puccinelli E, Gervasi PG, La Marca M, Beffy P, Longo V.

Xenobiotica. 2010 Aug;40(8):525-35. doi: 10.3109/00498254.2010.489125.

PMID:
20509749
15.

Molecular cloning and enzymatic characterization of sheep CYP2J.

Messina A, Nencioni S, Gervasi PG, Gotlinger KH, Schwartzman ML, Longo V.

Xenobiotica. 2010 Feb;40(2):109-18. doi: 10.3109/00498250903410590.

16.

Expression and distribution of CYP3A genes, CYP2B22, and MDR1, MRP1, MRP2, LRP efflux transporters in brain of control and rifampicin-treated pigs.

Nannelli A, Rossignolo F, Tolando R, Rossato P, Pellegatti M, Longo V, Gervasi PG.

Mol Cell Biochem. 2010 Apr;337(1-2):133-43. doi: 10.1007/s11010-009-0292-1. Epub 2009 Oct 22.

PMID:
19844775
17.

Effect of beta-naphthoflavone on AhR-regulated genes (CYP1A1, 1A2, 1B1, 2S1, Nrf2, and GST) and antioxidant enzymes in various brain regions of pig.

Nannelli A, Rossignolo F, Tolando R, Rossato P, Longo V, Gervasi PG.

Toxicology. 2009 Nov 30;265(3):69-79. doi: 10.1016/j.tox.2009.09.010. Epub 2009 Sep 26.

PMID:
19786062
18.

Expression and inducibility of CYP1A1, 1A2, 1B1 by beta-naphthoflavone and CYP2B22, 3A22, 3A29, 3A46 by rifampicin in the respiratory and olfactory mucosa of pig.

Messina A, Nannelli A, Fiorio R, Longo V, Gervasi PG.

Toxicology. 2009 Jun 16;260(1-3):47-52. doi: 10.1016/j.tox.2009.03.003. Epub 2009 Mar 20.

PMID:
19464568
19.

Purification, molecular cloning, heterologous expression and characterization of pig CYP1A2.

Messina A, Chirulli V, Gervasi PG, Longo V.

Xenobiotica. 2008 Dec;38(12):1453-70. doi: 10.1080/00498250802474437.

PMID:
18949657
20.

Expression and induction by rifampicin of CAR- and PXR-regulated CYP2B and CYP3A in liver, kidney and airways of pig.

Nannelli A, Chirulli V, Longo V, Gervasi PG.

Toxicology. 2008 Oct 30;252(1-3):105-12. doi: 10.1016/j.tox.2008.08.004. Epub 2008 Aug 22.

PMID:
18786598
21.

Inducibility of AhR-regulated CYP genes by beta-naphthoflavone in the liver, lung, kidney and heart of the pig.

Chirulli V, Marvasi L, Zaghini A, Fiorio R, Longo V, Gervasi PG.

Toxicology. 2007 Oct 30;240(1-2):25-37. Epub 2007 Jul 24.

PMID:
17804143
22.

Presence and inducibility by beta-naphthoflavone of CYP1A1, CYP1B1 and phase II enzymes in Trematomus bernacchii, an Antarctic fish.

Di Bello D, Vaccaro E, Longo V, Regoli F, Nigro M, Benedetti M, Gervasi PG, Pretti C.

Aquat Toxicol. 2007 Aug 15;84(1):19-26. Epub 2007 May 25.

PMID:
17643506
23.

Lisosan G, a powder of grain, does not interfere with the drug metabolizing enzymes and has a protective role on carbon tetrachloride-induced hepatotoxicity.

Longo V, Chirulli V, Gervasi PG, Nencioni S, Pellegrini M.

Biotechnol Lett. 2007 Aug;29(8):1155-9. Epub 2007 May 22.

PMID:
17516026
24.

Cloning, tissue expression, and inducibility of CYP 3A79 from sea bass (Dicentrarchus labrax).

Vaccaro E, Salvetti A, Del Carratore R, Nencioni S, Longo V, Gervasi PG.

J Biochem Mol Toxicol. 2007;21(1):32-40.

PMID:
17366542
25.

Effects of the anticancer dehydrotarplatin on cytochrome P450 and antioxidant enzymes in male rat tissues.

Nannelli A, Messina A, Marini S, Trasciatti S, Longo V, Gervasi PG.

Arch Toxicol. 2007 Jul;81(7):479-87. Epub 2007 Mar 16.

PMID:
17364183
26.

Expression, microsomal and mitochondrial activities of cytochrome P450 enzymes in brain regions from control and phenobarbital-treated rabbits.

Marini S, Nannelli A, Sodini D, Dragoni S, Valoti M, Longo V, Gervasi PG.

Life Sci. 2007 Feb 13;80(10):910-7. Epub 2006 Nov 16.

PMID:
17161434
27.

Effects of 17beta-estradiol, 4-nonylphenol and PCB 126 on the estrogenic activity and phase 1 and 2 biotransformation enzymes in male sea bass (Dicentrarchus labrax).

Vaccaro E, Meucci V, Intorre L, Soldani G, Di Bello D, Longo V, Gervasi PG, Pretti C.

Aquat Toxicol. 2005 Nov 30;75(4):293-305. Epub 2005 Oct 10.

PMID:
16219370
28.

Interactions between metabolism of trace metals and xenobiotic agonists of the aryl hydrocarbon receptor in the antarctic fish Trematomus bernacchii: environmental perspectives.

Regoli F, Nigro M, Benedetti M, Gorbi S, Pretti C, Gervasi PG, Fattorini D.

Environ Toxicol Chem. 2005 Jun;24(6):1475-82.

PMID:
16117125
29.

Expression and activity of CYP2E1 in circulating lymphocytes are not altered in diabetic individuals.

Pucci L, Chirulli V, Marini S, Lucchesi D, Penno G, Gervasi PG, Del Prato S, Longo V.

Pharmacol Res. 2005 Jun;51(6):561-5.

PMID:
15829437
30.

CAR and PXR expression and inducibility of CYP2B and CYP3A activities in rat and rabbit lungs.

Chirulli V, Longo V, Marini S, Mazzaccaro A, Fiorio R, Gervasi PG.

Life Sci. 2005 Apr 15;76(22):2535-46.

PMID:
15769478
31.

Effects of dioxane on cytochrome P450 enzymes in liver, kidney, lung and nasal mucosa of rat.

Nannelli A, De Rubertis A, Longo V, Gervasi PG.

Arch Toxicol. 2005 Feb;79(2):74-82. Epub 2004 Oct 15.

PMID:
15490126
32.

Effects of beta-naphthoflavone, phenobarbital and dichlobenil on the drug-metabolizing system of liver and nasal mucosa of Italian water frogs.

Longo V, Marini S, Salvetti A, Angelucci S, Bucci S, Gervasi PG.

Aquat Toxicol. 2004 Aug 25;69(3):259-70.

PMID:
15276331
33.

Trifluoroacetylated proteins in liver and plasma of guinea pigs treated with HCFC-123 and halothane.

Bortolato S, Zanovello A, Rugge M, Brotto M, Marini S, Gervasi PG, Manno M.

Toxicol Lett. 2003 Sep 15;144(1):35-47.

PMID:
12919722
34.
35.

l-Deprenyl metabolism by the cytochrome P450 system in monkey (Cercopithecus aethiops) liver microsomes.

Dragoni S, Bellik L, Frosini M, Sgaragli G, Marini S, Gervasi PG, Valoti M.

Xenobiotica. 2003 Feb;33(2):181-95.

PMID:
12623760
36.

4-Biphenylaldehyde and 9-anthraldehyde: two fluorescent substrates for determining P450 enzyme activities in rat and human.

Marini S, Grasso E, Longo V, Puccini P, Riccardi B, Gervasi PG.

Xenobiotica. 2003 Jan;33(1):1-11.

PMID:
12519690
37.

Inhibition of cytochrome p450 enzymes by enrofloxacin in the sea bass (Dicentrarchus labrax).

Vaccaro E, Giorgi M, Longo V, Mengozzi G, Gervasi PG.

Aquat Toxicol. 2003 Jan 10;62(1):27-33.

PMID:
12413791
38.

Selective inactivation of rat and bovine olfactory cytochrome P450 by three haloethanes.

Marini S, Longo V, Zaccaro C, De Matteis F, Gervasi PG.

Toxicol Lett. 2001 Oct 15;124(1-3):83-90.

PMID:
11684360
39.

Human cytochrome P450 2A6 is the major enzyme involved in the metabolism of three alkoxyethers used as oxyfuels.

Le Gal A, Dréano Y, Gervasi PG, Berthou F.

Toxicol Lett. 2001 Oct 15;124(1-3):47-58. Review.

PMID:
11684357
40.

Oxidation of N,N-dimethylformamide and N,N-diethylformamide by human liver microsomes and human recombinant P450s.

Amato G, Grasso E, Longo V, Gervasi PG.

Toxicol Lett. 2001 Oct 15;124(1-3):11-9.

PMID:
11684354
41.

Pharmacokinetics and microsomal oxidation of praziquantel and its effects on the P450 system in three-month-old lambs infested by Fasciola hepatica.

Giorgi M, Salvatori AP, Soldani G, Giusiani M, Longo V, Gervasi PG, Mengozzi G.

J Vet Pharmacol Ther. 2001 Aug;24(4):251-9.

PMID:
11555180
42.

Effects of beta-naphthoflavone on the cytochrome P450 system, and phase II enzymes in gilthead seabream (Sparus aurata).

Pretti C, Salvetti A, Longo V, Giorgi M, Gervasi PG.

Comp Biochem Physiol C Toxicol Pharmacol. 2001 Sep;130(1):133-44.

PMID:
11544149
43.

Stereochemical aspects in the 4-vinylcyclohexene biotransformation with rat liver microsomes and purified p450s. monoepoxides and diols.

Chiappe C, De Rubertis A, De Carlo M, Amato G, Gervasi PG.

Chem Res Toxicol. 2001 May;14(5):492-9.

PMID:
11368546
44.

Effect of starvation and chlormethiazole on cytochrome P450s of rat nasal mucosa.

Longo V, Ingelman-Sundberg M, Amato G, Salvetti A, Gervasi PG.

Biochem Pharmacol. 2000 Jun 1;59(11):1425-32.

PMID:
10751552
45.

Cloning and expression of rat CYP2E1 in Saccharomyces cerevisiae: detection of genotoxicity of N-alkylformamides.

Del Carratore MR, Mezzatesta C, Hidestrand M, Neve P, Amato G, Gervasi PG.

Environ Mol Mutagen. 2000;36(2):97-104.

PMID:
11013407
46.
47.

Cytochrome P450-dependent monooxygenase activities and their inducibility by classic P450 inducers in the liver, kidney, and nasal mucosa of male adult ring-necked pheasants.

Giorgi M, Marini S, Longo V, Mazzaccaro A, Amato G, Gervasi PG.

Toxicol Appl Pharmacol. 2000 Sep 15;167(3):237-45.

PMID:
10986015
48.

Heterogenous effects of anthraquinones on drug-metabolizing enzymes in the liver and small intestine of rat.

Longo V, Amato G, Salvetti A, Gervasi PG.

Chem Biol Interact. 2000 Apr 14;126(1):63-77.

PMID:
10826654
49.

Stabilization of cytochrome P4502E1 protein by ethanol in primary hamster hepatocyte cultures.

Zanelli U, Longo V, Paolicchi A, Gervasi PG.

Toxicol In Vitro. 2000 Feb;14(1):69-77.

PMID:
10699363
50.

Effect of clofibrate, a peroxisome proliferator, in sea bass (Dicentrarchus labrax), a marine fish.

Pretti C, Novi S, Longo V, Gervasi PG.

Environ Res. 1999 Apr;80(3):294-6.

PMID:
10092449

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