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Items: 1 to 50 of 61

1.

A transcription factor primes the condensin pump.

Gerton JL.

J Cell Biol. 2018 Jul 2;217(7):2233-2234. doi: 10.1083/jcb.201806043. Epub 2018 Jun 20.

PMID:
29925630
2.

Chromatin assembly factor-1 (CAF-1) chaperone regulates Cse4 deposition into chromatin in budding yeast.

Hewawasam GS, Dhatchinamoorthy K, Mattingly M, Seidel C, Gerton JL.

Nucleic Acids Res. 2018 May 18;46(9):4831. doi: 10.1093/nar/gky405. No abstract available.

3.

Regulation of kinetochore configuration during mitosis.

Dhatchinamoorthy K, Mattingly M, Gerton JL.

Curr Genet. 2018 Dec;64(6):1197-1203. doi: 10.1007/s00294-018-0841-9. Epub 2018 Apr 27. Review.

PMID:
29704052
4.

Integrative structure and functional anatomy of a nuclear pore complex.

Kim SJ, Fernandez-Martinez J, Nudelman I, Shi Y, Zhang W, Raveh B, Herricks T, Slaughter BD, Hogan JA, Upla P, Chemmama IE, Pellarin R, Echeverria I, Shivaraju M, Chaudhury AS, Wang J, Williams R, Unruh JR, Greenberg CH, Jacobs EY, Yu Z, de la Cruz MJ, Mironska R, Stokes DL, Aitchison JD, Jarrold MF, Gerton JL, Ludtke SJ, Akey CW, Chait BT, Sali A, Rout MP.

Nature. 2018 Mar 22;555(7697):475-482. doi: 10.1038/nature26003. Epub 2018 Mar 14.

5.

Chromatin assembly factor-1 (CAF-1) chaperone regulates Cse4 deposition into chromatin in budding yeast.

Hewawasam GS, Dhatchinamoorthy K, Mattingly M, Seidel C, Gerton JL.

Nucleic Acids Res. 2018 May 18;46(9):4440-4455. doi: 10.1093/nar/gky169.

6.

Mammalian oogenesis and female reproductive aging.

Duncan FE, Gerton JL.

Aging (Albany NY). 2018 Feb 5;10(2):162-163. doi: 10.18632/aging.101381. No abstract available.

7.

Taking cohesin and condensin in context.

Yuen KC, Gerton JL.

PLoS Genet. 2018 Jan 25;14(1):e1007118. doi: 10.1371/journal.pgen.1007118. eCollection 2018 Jan. Review.

8.

Age-associated dysregulation of protein metabolism in the mammalian oocyte.

Duncan FE, Jasti S, Paulson A, Kelsh JM, Fegley B, Gerton JL.

Aging Cell. 2017 Dec;16(6):1381-1393. doi: 10.1111/acel.12676. Epub 2017 Oct 10.

9.

Structural plasticity of the living kinetochore.

Dhatchinamoorthy K, Shivaraju M, Lange JJ, Rubinstein B, Unruh JR, Slaughter BD, Gerton JL.

J Cell Biol. 2017 Nov 6;216(11):3551-3570. doi: 10.1083/jcb.201703152. Epub 2017 Sep 22.

10.

DNA replication stress restricts ribosomal DNA copy number.

Salim D, Bradford WD, Freeland A, Cady G, Wang J, Pruitt SC, Gerton JL.

PLoS Genet. 2017 Sep 15;13(9):e1007006. doi: 10.1371/journal.pgen.1007006. eCollection 2017 Sep.

11.

Condensin II is anchored by TFIIIC and H3K4me3 in the mammalian genome and supports the expression of active dense gene clusters.

Yuen KC, Slaughter BD, Gerton JL.

Sci Adv. 2017 Jun 21;3(6):e1700191. doi: 10.1126/sciadv.1700191. eCollection 2017 Jun.

12.

Ribosomal DNA copy number loss and sequence variation in cancer.

Xu B, Li H, Perry JM, Singh VP, Unruh J, Yu Z, Zakari M, McDowell W, Li L, Gerton JL.

PLoS Genet. 2017 Jun 22;13(6):e1006771. doi: 10.1371/journal.pgen.1006771. eCollection 2017 Jun.

13.

Cornelia de Lange syndrome and molecular implications of the cohesin complex: Abstracts from the 7th biennial scientific and educational symposium 2016.

Kline AD, Krantz ID, Deardorff MA, Shirahige K, Dorsett D, Gerton JL, Wu M, Mehta D, Mills JA, Carrico CS, Noon S, Herrera PS, Horsfield JA, Bettale C, Morgan J, Huisman SA, Moss J, McCleery J, Grados M, Hansen BD, Srivastava S, Taylor-Snell E, Kerr LM, Katz O, Calof AL, Musio A, Egense A, Haaland RE.

Am J Med Genet A. 2017 May;173(5):1172-1185. doi: 10.1002/ajmg.a.38161. Epub 2017 Feb 12.

14.
15.

Mms21 SUMO Ligase Activity Promotes Nucleolar Function in Saccharomyces cerevisiae.

Kim DH, Harris B, Wang F, Seidel C, McCroskey S, Gerton JL.

Genetics. 2016 Oct;204(2):645-658. Epub 2016 Aug 10.

16.

Improved transcription and translation with L-leucine stimulation of mTORC1 in Roberts syndrome.

Xu B, Gogol M, Gaudenz K, Gerton JL.

BMC Genomics. 2016 Jan 5;17:25. doi: 10.1186/s12864-015-2354-y.

17.

NIPBL Controls RNA Biogenesis to Prevent Activation of the Stress Kinase PKR.

Yuen KC, Xu B, Krantz ID, Gerton JL.

Cell Rep. 2016 Jan 5;14(1):93-102. doi: 10.1016/j.celrep.2015.12.012. Epub 2015 Dec 24.

18.

Cohesin and human disease: lessons from mouse models.

Singh VP, Gerton JL.

Curr Opin Cell Biol. 2015 Dec;37:9-17. doi: 10.1016/j.ceb.2015.08.003. Epub 2015 Sep 11. Review.

19.

The SMC Loader Scc2 Promotes ncRNA Biogenesis and Translational Fidelity.

Zakari M, Trimble Ross R, Peak A, Blanchette M, Seidel C, Gerton JL.

PLoS Genet. 2015 Jul 15;11(7):e1005308. doi: 10.1371/journal.pgen.1005308. eCollection 2015 Jul.

20.

Clinical, developmental and molecular update on Cornelia de Lange syndrome and the cohesin complex: abstracts from the 2014 Scientific and Educational Symposium.

Kline AD, Calof AL, Lander AD, Gerton JL, Krantz ID, Dorsett D, Deardorff MA, Blagowidow N, Yokomori K, Shirahige K, Santos R, Woodman J, Megee PC, O'Connor JT, Egense A, Noon S, Belote M, Goodban MT, Hansen BD, Timmons JG, Musio A, Ishman SL, Bryan Y, Wu Y, Bettini LR, Mehta D, Zakari M, Mills JA, Srivastava S, Haaland RE.

Am J Med Genet A. 2015 Jun;167(6):1179-92. doi: 10.1002/ajmg.a.37056. Epub 2015 Apr 21.

PMID:
25899772
21.

Etiology and pathogenesis of the cohesinopathies.

Zakari M, Yuen K, Gerton JL.

Wiley Interdiscip Rev Dev Biol. 2015 Sep-Oct;4(5):489-504. doi: 10.1002/wdev.190. Epub 2015 Apr 7. Review.

PMID:
25847322
22.

The SMC loader Scc2 regulates gene expression.

Zakari M, Gerton JL.

Cell Cycle. 2015;14(7):943. doi: 10.1080/15384101.2015.1010959. No abstract available.

23.

L-leucine partially rescues translational and developmental defects associated with zebrafish models of Cornelia de Lange syndrome.

Xu B, Sowa N, Cardenas ME, Gerton JL.

Hum Mol Genet. 2015 Mar 15;24(6):1540-55. doi: 10.1093/hmg/ddu565. Epub 2014 Nov 6.

24.

Phosphorylation by casein kinase 2 facilitates Psh1 protein-assisted degradation of Cse4 protein.

Hewawasam GS, Mattingly M, Venkatesh S, Zhang Y, Florens L, Workman JL, Gerton JL.

J Biol Chem. 2014 Oct 17;289(42):29297-309. doi: 10.1074/jbc.M114.580589. Epub 2014 Sep 2.

25.

Roberts syndrome: A deficit in acetylated cohesin leads to nucleolar dysfunction.

Xu B, Lu S, Gerton JL.

Rare Dis. 2014 Jan 21;2:e27743. doi: 10.4161/rdis.27743. eCollection 2014.

26.

The cohesin acetyltransferase Eco1 coordinates rDNA replication and transcription.

Lu S, Lee KK, Harris B, Xiong B, Bose T, Saraf A, Hattem G, Florens L, Seidel C, Gerton JL.

EMBO Rep. 2014 May;15(5):609-17. doi: 10.1002/embr.201337974. Epub 2014 Mar 14.

27.

Cornelia de Lange syndrome: further delineation of phenotype, cohesin biology and educational focus, 5th Biennial Scientific and Educational Symposium abstracts.

Kline AD, Calof AL, Schaaf CA, Krantz ID, Jyonouchi S, Yokomori K, Gauze M, Carrico CS, Woodman J, Gerton JL, Vega H, Levin AV, Shirahige K, Champion M, Goodban MT, O'Connor JT, Pipan M, Horsfield J, Deardorff MA, Ishman SL, Dorsett D.

Am J Med Genet A. 2014 Jun;164A(6):1384-93. doi: 10.1002/ajmg.a.36417. Epub 2014 Feb 6.

PMID:
24504889
28.

Cohesion promotes nucleolar structure and function.

Harris B, Bose T, Lee KK, Wang F, Lu S, Ross RT, Zhang Y, French SL, Beyer AL, Slaughter BD, Unruh JR, Gerton JL.

Mol Biol Cell. 2014 Feb;25(3):337-46. doi: 10.1091/mbc.E13-07-0377. Epub 2013 Dec 4.

29.

Stimulation of mTORC1 with L-leucine rescues defects associated with Roberts syndrome.

Xu B, Lee KK, Zhang L, Gerton JL.

PLoS Genet. 2013;9(10):e1003857. doi: 10.1371/journal.pgen.1003857. Epub 2013 Oct 3.

30.

Translational mechanisms at work in the cohesinopathies.

Gerton JL.

Nucleus. 2012 Nov-Dec;3(6):520-5. doi: 10.4161/nucl.22800. Epub 2012 Nov 1.

31.

A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors.

Chen Z, McCrosky S, Guo W, Li H, Gerton JL.

G3 (Bethesda). 2012 Oct;2(10):1161-8. doi: 10.1534/g3.112.003327. Epub 2012 Oct 1.

32.

Cell-cycle-coupled structural oscillation of centromeric nucleosomes in yeast.

Shivaraju M, Unruh JR, Slaughter BD, Mattingly M, Berman J, Gerton JL.

Cell. 2012 Jul 20;150(2):304-16. doi: 10.1016/j.cell.2012.05.034.

33.

Cohesin proteins promote ribosomal RNA production and protein translation in yeast and human cells.

Bose T, Lee KK, Lu S, Xu B, Harris B, Slaughter B, Unruh J, Garrett A, McDowell W, Box A, Li H, Peak A, Ramachandran S, Seidel C, Gerton JL.

PLoS Genet. 2012;8(6):e1002749. doi: 10.1371/journal.pgen.1002749. Epub 2012 Jun 14.

34.

The dynamics of the Cse4 chaperone Scm3.

Shivaraju M, Gerton JL.

Cell Cycle. 2011 Nov 15;10(22):3823-4. doi: 10.4161/cc.10.22.18232. Epub 2011 Nov 15. No abstract available.

PMID:
22142858
35.

Scm3 is a centromeric nucleosome assembly factor.

Shivaraju M, Camahort R, Mattingly M, Gerton JL.

J Biol Chem. 2011 Apr 8;286(14):12016-23. doi: 10.1074/jbc.M110.183640. Epub 2011 Feb 12.

36.

Cse4 gets a kiss-of-death from Psh1.

Hewawasam GS, Gerton JL.

Cell Cycle. 2011 Feb 15;10(4):566-7. Epub 2011 Feb 15. No abstract available.

PMID:
21293184
37.

Psh1 is an E3 ubiquitin ligase that targets the centromeric histone variant Cse4.

Hewawasam G, Shivaraju M, Mattingly M, Venkatesh S, Martin-Brown S, Florens L, Workman JL, Gerton JL.

Mol Cell. 2010 Nov 12;40(3):444-54. doi: 10.1016/j.molcel.2010.10.014.

38.

Hos1 is a lysine deacetylase for the Smc3 subunit of cohesin.

Xiong B, Lu S, Gerton JL.

Curr Biol. 2010 Sep 28;20(18):1660-5. doi: 10.1016/j.cub.2010.08.019.

39.

Eco1 is important for DNA damage repair in S. cerevisiae.

Lu S, Goering M, Gard S, Xiong B, McNairn AJ, Jaspersen SL, Gerton JL.

Cell Cycle. 2010 Aug 15;9(16):3315-27. doi: 10.4161/cc.9.16.12673. Epub 2010 Aug 14.

40.

Cohesinopathies, gene expression, and chromatin organization.

Bose T, Gerton JL.

J Cell Biol. 2010 Apr 19;189(2):201-10. doi: 10.1083/jcb.200912129. Review.

41.

Regulators of the cohesin network.

Xiong B, Gerton JL.

Annu Rev Biochem. 2010;79:131-53. doi: 10.1146/annurev-biochem-061708-092640. Review.

PMID:
20331362
42.

Cohesinopathy mutations disrupt the subnuclear organization of chromatin.

Gard S, Light W, Xiong B, Bose T, McNairn AJ, Harris B, Fleharty B, Seidel C, Brickner JH, Gerton JL.

J Cell Biol. 2009 Nov 16;187(4):455-62. doi: 10.1083/jcb.200906075. Epub 2009 Nov 9. Erratum in: J Cell Biol. 2009 Nov 30;187(5):749.

43.

Cse4 is part of an octameric nucleosome in budding yeast.

Camahort R, Shivaraju M, Mattingly M, Li B, Nakanishi S, Zhu D, Shilatifard A, Workman JL, Gerton JL.

Mol Cell. 2009 Sep 24;35(6):794-805. doi: 10.1016/j.molcel.2009.07.022.

44.

Intersection of ChIP and FLIP, genomic methods to study the dynamics of the cohesin proteins.

McNairn AJ, Gerton JL.

Chromosome Res. 2009;17(2):155-63. doi: 10.1007/s10577-008-9007-9.

PMID:
19308698
45.

Cohesinopathies: One ring, many obligations.

McNairn AJ, Gerton JL.

Mutat Res. 2008 Dec 1;647(1-2):103-11. doi: 10.1016/j.mrfmmm.2008.08.010. Epub 2008 Aug 22. Review.

PMID:
18786550
46.

The chromosome glue gets a little stickier.

McNairn AJ, Gerton JL.

Trends Genet. 2008 Aug;24(8):382-9. doi: 10.1016/j.tig.2008.06.002. Epub 2008 Jul 2. Review.

PMID:
18602182
47.

Transcription alters chromosomal locations of cohesin in Saccharomyces cerevisiae.

Bausch C, Noone S, Henry JM, Gaudenz K, Sanderson B, Seidel C, Gerton JL.

Mol Cell Biol. 2007 Dec;27(24):8522-32. Epub 2007 Oct 8.

48.

Scm3 is essential to recruit the histone h3 variant cse4 to centromeres and to maintain a functional kinetochore.

Camahort R, Li B, Florens L, Swanson SK, Washburn MP, Gerton JL.

Mol Cell. 2007 Jun 22;26(6):853-65. Epub 2007 Jun 14.

49.

Enhancing togetherness: kinetochores and cohesion.

Gerton JL.

Genes Dev. 2007 Feb 1;21(3):238-41. Review. No abstract available.

50.

The overexpression of a Saccharomyces cerevisiae centromeric histone H3 variant mutant protein leads to a defect in kinetochore biorientation.

Collins KA, Camahort R, Seidel C, Gerton JL, Biggins S.

Genetics. 2007 Feb;175(2):513-25. Epub 2006 Dec 6.

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