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Items: 23


Identification of Pathogen Genomic Differences That Impact Human Immune Response and Disease during Cryptococcus neoformans Infection.

Gerstein AC, Jackson KM, McDonald TR, Wang Y, Lueck BD, Bohjanen S, Smith KD, Akampurira A, Meya DB, Xue C, Boulware DR, Nielsen K.

MBio. 2019 Jul 16;10(4). pii: e01440-19. doi: 10.1128/mBio.01440-19.


Variable gene transcription underlies phenotypic convergence of hypoxia tolerance in sculpins.

Mandic M, Ramon ML, Gerstein AC, Gracey AY, Richards JG.

BMC Evol Biol. 2018 Nov 3;18(1):163. doi: 10.1186/s12862-018-1275-1.


Quantifying how constraints limit the diversity of viable routes to adaptation.

Yeaman S, Gerstein AC, Hodgins KA, Whitlock MC.

PLoS Genet. 2018 Oct 8;14(10):e1007717. doi: 10.1371/journal.pgen.1007717. eCollection 2018 Oct.


Rapid Phenotypic and Genotypic Diversification After Exposure to the Oral Host Niche in Candida albicans.

Forche A, Cromie G, Gerstein AC, Solis NV, Pisithkul T, Srifa W, Jeffery E, Abbey D, Filler SG, Dudley AM, Berman J.

Genetics. 2018 Jul;209(3):725-741. doi: 10.1534/genetics.118.301019. Epub 2018 May 3.


Ploidy tug-of-war: Evolutionary and genetic environments influence the rate of ploidy drive in a human fungal pathogen.

Gerstein AC, Lim H, Berman J, Hickman MA.

Evolution. 2017 Apr;71(4):1025-1038. doi: 10.1111/evo.13205. Epub 2017 Mar 24. Erratum in: Evolution. 2017 Jul;71(7):1922.


Widespread Genetic Incompatibilities between First-Step Mutations during Parallel Adaptation of Saccharomyces cerevisiae to a Common Environment.

Ono J, Gerstein AC, Otto SP.

PLoS Biol. 2017 Jan 23;15(1):e1002591. doi: 10.1371/journal.pbio.1002591. eCollection 2017 Jan.


It's not all about us: evolution and maintenance of Cryptococcus virulence requires selection outside the human host.

Gerstein AC, Nielsen K.

Yeast. 2017 Apr;34(4):143-154. doi: 10.1002/yea.3222. Epub 2017 Jan 12.


diskImageR: quantification of resistance and tolerance to antimicrobial drugs using disk diffusion assays.

Gerstein AC, Rosenberg A, Hecht I, Berman J.

Microbiology. 2016 Jul;162(7):1059-68. doi: 10.1099/mic.0.000295. Epub 2016 Apr 27.


Polyploid titan cells produce haploid and aneuploid progeny to promote stress adaptation.

Gerstein AC, Fu MS, Mukaremera L, Li Z, Ormerod KL, Fraser JA, Berman J, Nielsen K.

MBio. 2015 Oct 13;6(5):e01340-15. doi: 10.1128/mBio.01340-15.


Shift and adapt: the costs and benefits of karyotype variations.

Gerstein AC, Berman J.

Curr Opin Microbiol. 2015 Aug;26:130-6. doi: 10.1016/j.mib.2015.06.010. Epub 2015 Aug 25. Review.


Too much of a good thing: the unique and repeated paths toward copper adaptation.

Gerstein AC, Ono J, Lo DS, Campbell ML, Kuzmin A, Otto SP.

Genetics. 2015 Feb;199(2):555-71. doi: 10.1534/genetics.114.171124. Epub 2014 Dec 17.


Silencing is noisy: population and cell level noise in telomere-adjacent genes is dependent on telomere position and sir2.

Anderson MZ, Gerstein AC, Wigen L, Baller JA, Berman J.

PLoS Genet. 2014 Jul 24;10(7):e1004436. doi: 10.1371/journal.pgen.1004436. eCollection 2014 Jul.


Loss-of-heterozygosity facilitates passage through Haldane's sieve for Saccharomyces cerevisiae undergoing adaptation.

Gerstein AC, Kuzmin A, Otto SP.

Nat Commun. 2014 May 7;5:3819. doi: 10.1038/ncomms4819.


Mutational effects depend on ploidy level: all else is not equal.

Gerstein AC.

Biol Lett. 2013 Feb 23;9(1):20120614. doi: 10.1098/rsbl.2012.0614. Epub 2012 Oct 10.


Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of drug resistance in yeast.

Gerstein AC, Lo DS, Otto SP.

Genetics. 2012 Sep;192(1):241-52. doi: 10.1534/genetics.112.142620. Epub 2012 Jun 19.


Cryptic fitness advantage: diploids invade haploid populations despite lacking any apparent advantage as measured by standard fitness assays.

Gerstein AC, Otto SP.

PLoS One. 2011;6(12):e26599. doi: 10.1371/journal.pone.0026599. Epub 2011 Dec 9.


Small is the new big: assessing the population structure of microorganisms.

Gerstein AC, Jean-S├ębastien M.

Mol Ecol. 2011 Nov;20(21):4385-7.


Haploids adapt faster than diploids across a range of environments.

Gerstein AC, Cleathero LA, Mandegar MA, Otto SP.

J Evol Biol. 2011 Mar;24(3):531-40. doi: 10.1111/j.1420-9101.2010.02188.x. Epub 2010 Dec 16.


Ploidy and the causes of genomic evolution.

Gerstein AC, Otto SP.

J Hered. 2009 Sep-Oct;100(5):571-81. doi: 10.1093/jhered/esp057. Epub 2009 Jul 22. Review.


The evolution of haploidy and diploidy.

Otto SP, Gerstein AC.

Curr Biol. 2008 Dec 23;18(24):R1121-4. doi: 10.1016/j.cub.2008.09.039. No abstract available.


Ploidy reduction in Saccharomyces cerevisiae.

Gerstein AC, McBride RM, Otto SP.

Biol Lett. 2008 Feb 23;4(1):91-4.


Genomic convergence toward diploidy in Saccharomyces cerevisiae.

Gerstein AC, Chun HJ, Grant A, Otto SP.

PLoS Genet. 2006 Sep 22;2(9):e145.


Why have sex? The population genetics of sex and recombination.

Otto SP, Gerstein AC.

Biochem Soc Trans. 2006 Aug;34(Pt 4):519-22. Review.


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