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Items: 15


Affinity-enhanced T-cell receptors for adoptive T-cell therapy targeting MAGE-A10: strategy for selection of an optimal candidate.

Border EC, Sanderson JP, Weissensteiner T, Gerry AB, Pumphrey NJ.

Oncoimmunology. 2018 Nov 20;8(2):e1532759. doi: 10.1080/2162402X.2018.1532759. eCollection 2019.


Tuning T-Cell Receptor Affinity to Optimize Clinical Risk-Benefit When Targeting Alpha-Fetoprotein-Positive Liver Cancer.

Docta RY, Ferronha T, Sanderson JP, Weissensteiner T, Pope GR, Bennett AD, Pumphrey NJ, Ferjentsik Z, Quinn LL, Wiedermann GE, Anderson VE, Saini M, Maroto M, Norry E, Gerry AB.

Hepatology. 2019 May;69(5):2061-2075. doi: 10.1002/hep.30477. Epub 2019 Feb 14.


Histone Deacetylase Inhibitors Enhance CD4 T Cell Susceptibility to NK Cell Killing but Reduce NK Cell Function.

Pace M, Williams J, Kurioka A, Gerry AB, Jakobsen B, Klenerman P, Nwokolo N, Fox J, Fidler S, Frater J; CHERUB Investigators.

PLoS Pathog. 2016 Aug 16;12(8):e1005782. doi: 10.1371/journal.ppat.1005782. eCollection 2016 Aug.


Human leucocyte antigen class I-redirected anti-tumour CD4+ T cells require a higher T cell receptor binding affinity for optimal activity than CD8+ T cells.

Tan MP, Dolton GM, Gerry AB, Brewer JE, Bennett AD, Pumphrey NJ, Jakobsen BK, Sewell AK.

Clin Exp Immunol. 2017 Jan;187(1):124-137. doi: 10.1111/cei.12828. Epub 2016 Nov 14.


NY-ESO-1-specific TCR-engineered T cells mediate sustained antigen-specific antitumor effects in myeloma.

Rapoport AP, Stadtmauer EA, Binder-Scholl GK, Goloubeva O, Vogl DT, Lacey SF, Badros AZ, Garfall A, Weiss B, Finklestein J, Kulikovskaya I, Sinha SK, Kronsberg S, Gupta M, Bond S, Melchiori L, Brewer JE, Bennett AD, Gerry AB, Pumphrey NJ, Williams D, Tayton-Martin HK, Ribeiro L, Holdich T, Yanovich S, Hardy N, Yared J, Kerr N, Philip S, Westphal S, Siegel DL, Levine BL, Jakobsen BK, Kalos M, June CH.

Nat Med. 2015 Aug;21(8):914-921. doi: 10.1038/nm.3910. Epub 2015 Jul 20.


T cell receptor binding affinity governs the functional profile of cancer-specific CD8+ T cells.

Tan MP, Gerry AB, Brewer JE, Melchiori L, Bridgeman JS, Bennett AD, Pumphrey NJ, Jakobsen BK, Price DA, Ladell K, Sewell AK.

Clin Exp Immunol. 2015 May;180(2):255-70. doi: 10.1111/cei.12570.


Effect of low extracellular pH on NF-κB activation in macrophages.

Gerry AB, Leake DS.

Atherosclerosis. 2014 Apr;233(2):537-44. doi: 10.1016/j.atherosclerosis.2014.01.014. Epub 2014 Jan 21.


Examining the presentation of tumor-associated antigens on peptide-pulsed T2 cells.

Bossi G, Gerry AB, Paston SJ, Sutton DH, Hassan NJ, Jakobsen BK.

Oncoimmunology. 2013 Nov 1;2(11):e26840. Epub 2013 Oct 21.


Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells.

Cameron BJ, Gerry AB, Dukes J, Harper JV, Kannan V, Bianchi FC, Grand F, Brewer JE, Gupta M, Plesa G, Bossi G, Vuidepot A, Powlesland AS, Legg A, Adams KJ, Bennett AD, Pumphrey NJ, Williams DD, Binder-Scholl G, Kulikovskaya I, Levine BL, Riley JL, Varela-Rohena A, Stadtmauer EA, Rapoport AP, Linette GP, June CH, Hassan NJ, Kalos M, Jakobsen BK.

Sci Transl Med. 2013 Aug 7;5(197):197ra103. doi: 10.1126/scitranslmed.3006034.


Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma.

Linette GP, Stadtmauer EA, Maus MV, Rapoport AP, Levine BL, Emery L, Litzky L, Bagg A, Carreno BM, Cimino PJ, Binder-Scholl GK, Smethurst DP, Gerry AB, Pumphrey NJ, Bennett AD, Brewer JE, Dukes J, Harper J, Tayton-Martin HK, Jakobsen BK, Hassan NJ, Kalos M, June CH.

Blood. 2013 Aug 8;122(6):863-71. doi: 10.1182/blood-2013-03-490565. Epub 2013 Jun 14.


A moderate reduction in extracellular pH protects macrophages against apoptosis induced by oxidized low density lipoprotein.

Gerry AB, Leake DS.

J Lipid Res. 2008 Apr;49(4):782-9. doi: 10.1194/jlr.M700349-JLR200. Epub 2008 Jan 17.


A novel method for production of lipid hydroperoxide- or oxysterol-rich low-density lipoprotein.

Gerry AB, Satchell L, Leake DS.

Atherosclerosis. 2008 Apr;197(2):579-87. Epub 2007 Oct 22.


Aqueous peroxyl radical exposure to THP-1 cells causes glutathione loss followed by protein oxidation and cell death without increased caspase-3 activity.

Kappler M, Gerry AB, Brown E, Reid L, Leake DS, Gieseg SP.

Biochim Biophys Acta. 2007 Jun;1773(6):945-53. Epub 2007 Apr 12.


Common variants of apolipoprotein A-IV differ in their ability to inhibit low density lipoprotein oxidation.

Wong WM, Gerry AB, Putt W, Roberts JL, Weinberg RB, Humphries SE, Leake DS, Talmud PJ.

Atherosclerosis. 2007 Jun;192(2):266-74. Epub 2006 Sep 1.


Effects of dairy products naturally enriched with cis-9,trans-11 conjugated linoleic acid on the blood lipid profile in healthy middle-aged men.

Tricon S, Burdge GC, Jones EL, Russell JJ, El-Khazen S, Moretti E, Hall WL, Gerry AB, Leake DS, Grimble RF, Williams CM, Calder PC, Yaqoob P.

Am J Clin Nutr. 2006 Apr;83(4):744-53.


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