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Items: 39


Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells.

Estoppey D, Hewett JW, Guy CT, Harrington E, Thomas JR, Schirle M, Cuttat R, Waldt A, Gerrits B, Yang Z, Schuierer S, Pan X, Xie K, Carbone W, Knehr J, Lindeman A, Russ C, Frias E, Hoffman GR, Varadarajan M, Ramadan N, Reece-Hoyes JS, Wang Q, Chen X, McAllister G, Roma G, Bouwmeester T, Hoepfner D.

Sci Rep. 2017 Feb 16;7:42728. doi: 10.1038/srep42728.


Two Antagonistic MALT1 Auto-Cleavage Mechanisms Reveal a Role for TRAF6 to Unleash MALT1 Activation.

Ginster S, Bardet M, Unterreiner A, Malinverni C, Renner F, Lam S, Freuler F, Gerrits B, Voshol J, Calzascia T, Régnier CH, Renatus M, Nikolay R, Israël L, Bornancin F.

PLoS One. 2017 Jan 4;12(1):e0169026. doi: 10.1371/journal.pone.0169026. eCollection 2017.


Exploring Glucocorticoid Receptor Agonists Mechanism of Action Through Mass Cytometry and Radial Visualizations.

Abraham Y, Gerrits B, Ludwig MG, Rebhan M, Gubser Keller C.

Cytometry B Clin Cytom. 2017 Jan;92(1):42-56. doi: 10.1002/cyto.b.21499.


Identification of Novel Death-Associated Protein Kinase 2 Interaction Partners by Proteomic Screening Coupled with Bimolecular Fluorescence Complementation.

Geering B, Zokouri Z, Hürlemann S, Gerrits B, Ausländer D, Britschgi A, Tschan MP, Simon HU, Fussenegger M.

Mol Cell Biol. 2015 Oct 19;36(1):132-43. doi: 10.1128/MCB.00515-15. Print 2016 Jan 1.


Surfaceome of classical Hodgkin and non-Hodgkin lymphoma.

Hofmann A, Thiesler T, Gerrits B, Behnke S, Sobotzki N, Omasits U, Bausch-Fluck D, Bock T, Aebersold R, Moch H, Tinguely M, Wollscheid B.

Proteomics Clin Appl. 2015 Aug;9(7-8):661-70. doi: 10.1002/prca.201400146.


Chemical genetic approach identifies microtubule affinity-regulating kinase 1 as a leucine-rich repeat kinase 2 substrate.

Krumova P, Reyniers L, Meyer M, Lobbestael E, Stauffer D, Gerrits B, Muller L, Hoving S, Kaupmann K, Voshol J, Fabbro D, Bauer A, Rovelli G, Taymans JM, Bouwmeester T, Baekelandt V.

FASEB J. 2015 Jul;29(7):2980-92. doi: 10.1096/fj.14-262329. Epub 2015 Apr 8.


Scalable production in human cells and biochemical characterization of full-length normal and mutant huntingtin.

Huang B, Lucas T, Kueppers C, Dong X, Krause M, Bepperling A, Buchner J, Voshol H, Weiss A, Gerrits B, Kochanek S.

PLoS One. 2015 Mar 23;10(3):e0121055. doi: 10.1371/journal.pone.0121055. eCollection 2015.


EEG biofeedback for autism spectrum disorders: a reply to a commentary by Coben and Ricca (2014).

van Schie HT, Gerrits BJ, Buitelaar JK, Kouijzer ME.

Appl Psychophysiol Biofeedback. 2015 Mar;40(1):57-60. doi: 10.1007/s10484-015-9272-2. No abstract available.


Quantitative Lys-ϵ-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1.

Thompson JW, Nagel J, Hoving S, Gerrits B, Bauer A, Thomas JR, Kirschner MW, Schirle M, Luchansky SJ.

J Biol Chem. 2014 Oct 17;289(42):28942-55. doi: 10.1074/jbc.M114.573352. Epub 2014 Aug 21.


Prolyl isomerase PIN1 regulates DNA double-strand break repair by counteracting DNA end resection.

Steger M, Murina O, Hühn D, Ferretti LP, Walser R, Hänggi K, Lafranchi L, Neugebauer C, Paliwal S, Janscak P, Gerrits B, Del Sal G, Zerbe O, Sartori AA.

Mol Cell. 2013 May 9;50(3):333-43. doi: 10.1016/j.molcel.2013.03.023. Epub 2013 Apr 25.


Protein complex interactor analysis and differential activity of KDM3 subfamily members towards H3K9 methylation.

Brauchle M, Yao Z, Arora R, Thigale S, Clay I, Inverardi B, Fletcher J, Taslimi P, Acker MG, Gerrits B, Voshol J, Bauer A, Schübeler D, Bouwmeester T, Ruffner H.

PLoS One. 2013 Apr 11;8(4):e60549. doi: 10.1371/journal.pone.0060549. Print 2013.


Extracellular signal-regulated kinase and glycogen synthase kinase 3β regulate gephyrin postsynaptic aggregation and GABAergic synaptic function in a calpain-dependent mechanism.

Tyagarajan SK, Ghosh H, Yévenes GE, Imanishi SY, Zeilhofer HU, Gerrits B, Fritschy JM.

J Biol Chem. 2013 Apr 5;288(14):9634-47. doi: 10.1074/jbc.M112.442616. Epub 2013 Feb 13.


Is EEG-biofeedback an effective treatment in autism spectrum disorders? A randomized controlled trial.

Kouijzer ME, van Schie HT, Gerrits BJ, Buitelaar JK, de Moor JM.

Appl Psychophysiol Biofeedback. 2013 Mar;38(1):17-28. doi: 10.1007/s10484-012-9204-3.


Comparative phosphoproteome profiling reveals a function of the STN8 kinase in fine-tuning of cyclic electron flow (CEF).

Reiland S, Finazzi G, Endler A, Willig A, Baerenfaller K, Grossmann J, Gerrits B, Rutishauser D, Gruissem W, Rochaix JD, Baginsky S.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12955-60. doi: 10.1073/pnas.1104734108. Epub 2011 Jul 18.


Proteome profiling suggests a pro-inflammatory role for plasma cells through release of high-mobility group box 1 protein.

Vettermann C, Castor D, Mekker A, Gerrits B, Karas M, Jäck HM.

Proteomics. 2011 Apr;11(7):1228-37. doi: 10.1002/pmic.201000491. Epub 2011 Feb 14.


Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.

Bodenmiller B, Wanka S, Kraft C, Urban J, Campbell D, Pedrioli PG, Gerrits B, Picotti P, Lam H, Vitek O, Brusniak MY, Roschitzki B, Zhang C, Shokat KM, Schlapbach R, Colman-Lerner A, Nolan GP, Nesvizhskii AI, Peter M, Loewith R, von Mering C, Aebersold R.

Sci Signal. 2010 Dec 21;3(153):rs4. doi: 10.1126/scisignal.2001182.


Regulation of GABAergic synapse formation and plasticity by GSK3beta-dependent phosphorylation of gephyrin.

Tyagarajan SK, Ghosh H, Yévenes GE, Nikonenko I, Ebeling C, Schwerdel C, Sidler C, Zeilhofer HU, Gerrits B, Muller D, Fritschy JM.

Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):379-84. doi: 10.1073/pnas.1011824108. Epub 2010 Dec 20.


Molecular characterization of a trafficking organelle: dissecting the axonal paths of calsyntenin-1 transport vesicles.

Steuble M, Gerrits B, Ludwig A, Mateos JM, Diep TM, Tagaya M, Stephan A, Schätzle P, Kunz B, Streit P, Sonderegger P.

Proteomics. 2010 Nov;10(21):3775-88. doi: 10.1002/pmic.201000384.


Transcriptional profiling of ErbB signalling in mammary luminal epithelial cells--interplay of ErbB and IGF1 signalling through IGFBP3 regulation.

Worthington J, Bertani M, Chan HL, Gerrits B, Timms JF.

BMC Cancer. 2010 Sep 14;10:490. doi: 10.1186/1471-2407-10-490.


Mapping of phosphorylation sites by LC-MS/MS.

Gerrits B, Bodenmiller B.

Methods Mol Biol. 2010;658:127-36. doi: 10.1007/978-1-60761-780-8_7.


Proteomic cell surface phenotyping of differentiating acute myeloid leukemia cells.

Hofmann A, Gerrits B, Schmidt A, Bock T, Bausch-Fluck D, Aebersold R, Wollscheid B.

Blood. 2010 Sep 30;116(13):e26-34. doi: 10.1182/blood-2010-02-271270. Epub 2010 Jun 22.


Proteome analysis of fungal and bacterial involvement in leaf litter decomposition.

Schneider T, Gerrits B, Gassmann R, Schmid E, Gessner MO, Richter A, Battin T, Eberl L, Riedel K.

Proteomics. 2010 May;10(9):1819-30. doi: 10.1002/pmic.200900691.


Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogaster.

Goetze S, Qeli E, Mosimann C, Staes A, Gerrits B, Roschitzki B, Mohanty S, Niederer EM, Laczko E, Timmerman E, Lange V, Hafen E, Aebersold R, Vandekerckhove J, Basler K, Ahrens CH, Gevaert K, Brunner E.

PLoS Biol. 2009 Nov;7(11):e1000236. doi: 10.1371/journal.pbio.1000236. Epub 2009 Nov 3.


Proteomic analysis in aortic media of patients with Marfan syndrome reveals increased activity of calpain 2 in aortic aneurysms.

Pilop C, Aregger F, Gorman RC, Brunisholz R, Gerrits B, Schaffner T, Gorman JH 3rd, Matyas G, Carrel T, Frey BM.

Circulation. 2009 Sep 15;120(11):983-91. doi: 10.1161/CIRCULATIONAHA.108.843516. Epub 2009 Aug 31. Erratum in: Circulation. 2010 Feb 16;121(6):e38.


Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.

Huber A, Bodenmiller B, Uotila A, Stahl M, Wanka S, Gerrits B, Aebersold R, Loewith R.

Genes Dev. 2009 Aug 15;23(16):1929-43. doi: 10.1101/gad.532109.


Large-scale Arabidopsis phosphoproteome profiling reveals novel chloroplast kinase substrates and phosphorylation networks.

Reiland S, Messerli G, Baerenfaller K, Gerrits B, Endler A, Grossmann J, Gruissem W, Baginsky S.

Plant Physiol. 2009 Jun;150(2):889-903. doi: 10.1104/pp.109.138677. Epub 2009 Apr 17.


MRE11 complex links RECQ5 helicase to sites of DNA damage.

Zheng L, Kanagaraj R, Mihaljevic B, Schwendener S, Sartori AA, Gerrits B, Shevelev I, Janscak P.

Nucleic Acids Res. 2009 May;37(8):2645-57. doi: 10.1093/nar/gkp147. Epub 2009 Mar 6.


Neuronal Nogo-A modulates growth cone motility via Rho-GTP/LIMK1/cofilin in the unlesioned adult nervous system.

Montani L, Gerrits B, Gehrig P, Kempf A, Dimou L, Wollscheid B, Schwab ME.

J Biol Chem. 2009 Apr 17;284(16):10793-807. doi: 10.1074/jbc.M808297200. Epub 2009 Feb 9.


In vivo phosphorylation sites of barley tonoplast proteins identified by a phosphoproteomic approach.

Endler A, Reiland S, Gerrits B, Schmidt UG, Baginsky S, Martinoia E.

Proteomics. 2009 Jan;9(2):310-21. doi: 10.1002/pmic.200800323.


PhosphoPep--a database of protein phosphorylation sites in model organisms.

Bodenmiller B, Campbell D, Gerrits B, Lam H, Jovanovic M, Picotti P, Schlapbach R, Aebersold R.

Nat Biotechnol. 2008 Dec;26(12):1339-40. doi: 10.1038/nbt1208-1339. No abstract available.


Pin1 interacts with c-Myb in a phosphorylation-dependent manner and regulates its transactivation activity.

Pani E, Menigatti M, Schubert S, Hess D, Gerrits B, Klempnauer KH, Ferrari S.

Biochim Biophys Acta. 2008 Jun;1783(6):1121-8. doi: 10.1016/j.bbamcr.2008.02.020. Epub 2008 Mar 5.


PhosphoPep--a phosphoproteome resource for systems biology research in Drosophila Kc167 cells.

Bodenmiller B, Malmstrom J, Gerrits B, Campbell D, Lam H, Schmidt A, Rinner O, Mueller LN, Shannon PT, Pedrioli PG, Panse C, Lee HK, Schlapbach R, Aebersold R.

Mol Syst Biol. 2007;3:139. Epub 2007 Oct 16. Review.


The Mass Distance Fingerprint: a statistical framework for de novo detection of predominant modifications using high-accuracy mass spectrometry.

Potthast F, Gerrits B, Häkkinen J, Rutishauser D, Ahrens CH, Roschitzki B, Baerenfaller K, Munton RP, Walther P, Gehrig P, Seif P, Seeberger PH, Schlapbach R.

J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jul 1;854(1-2):173-82. Epub 2007 Apr 25.


Differential display and protein quantification.

Brunner E, Gerrits B, Scott M, Roschitzki B.

EXS. 2007;97:115-40. Review.


Ultrahigh mass resolution and accurate mass measurements as a tool to characterize oligomers in secondary organic aerosols.

Reinhardt A, Emmenegger C, Gerrits B, Panse C, Dommen J, Baltensperger U, Zenobi R, Kalberer M.

Anal Chem. 2007 Jun 1;79(11):4074-82. Epub 2007 Apr 6.


Estrogen receptor-ligand complexes measured by chip-based nanoelectrospray mass spectrometry: an approach for the screening of endocrine disruptors.

Bovet C, Wortmann A, Eiler S, Granger F, Ruff M, Gerrits B, Moras D, Zenobi R.

Protein Sci. 2007 May;16(5):938-46. Epub 2007 Mar 30.


Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.

Cannavo E, Gerrits B, Marra G, Schlapbach R, Jiricny J.

J Biol Chem. 2007 Feb 2;282(5):2976-86. Epub 2006 Dec 4.


Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

Munton RP, Tweedie-Cullen R, Livingstone-Zatchej M, Weinandy F, Waidelich M, Longo D, Gehrig P, Potthast F, Rutishauser D, Gerrits B, Panse C, Schlapbach R, Mansuy IM.

Mol Cell Proteomics. 2007 Feb;6(2):283-93. Epub 2006 Nov 17.


Preparative two-dimensional gel electrophoresis at alkaline pH using narrow range immobilized pH gradients.

Hoving S, Gerrits B, Voshol H, Müller D, Roberts RC, van Oostrum J.

Proteomics. 2002 Feb;2(2):127-34.


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