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Items: 27


Disseminated Pneumocystis jirovecii Infection with Osteomyelitis in a Patient with CTLA-4 Haploinsufficiency.

Siddiqi AE, Liu AY, Charville GW, Kunder CA, Uzel G, Sadighi Akha AA, Oak J, Martin B, Sacha J, Lewis DB, Gernez Y.

J Clin Immunol. 2020 Jan 18. doi: 10.1007/s10875-020-00748-z. [Epub ahead of print] No abstract available.


Severe autoinflammation in 4 patients with C-terminal variants in cell division control protein 42 homolog (CDC42) successfully treated with IL-1β inhibition.

Gernez Y, de Jesus AA, Alsaleem H, Macaubas C, Roy A, Lovell D, Jagadeesh KA, Alehashemi S, Erdman L, Grimley M, Talarico S, Bacchetta R, Lewis DB, Canna SW, Laxer RM, Mellins ED, Goldbach-Mansky R, Weinacht KG.

J Allergy Clin Immunol. 2019 Oct;144(4):1122-1125.e6. doi: 10.1016/j.jaci.2019.06.017. Epub 2019 Jul 2. No abstract available.


Humoral immunodeficiencies: conferred risk of infections and benefits of immunoglobulin replacement therapy.

Gernez Y, Baker MG, Maglione PJ.

Transfusion. 2018 Dec;58 Suppl 3:3056-3064. doi: 10.1111/trf.15020. Review.


Resistin is elevated in cystic fibrosis sputum and correlates negatively with lung function.

Forrest OA, Chopyk DM, Gernez Y, Brown MR, Conrad CK, Moss RB, Tangpricha V, Peng L, Tirouvanziam R.

J Cyst Fibros. 2019 Jan;18(1):64-70. doi: 10.1016/j.jcf.2018.05.018. Epub 2018 Jun 21.


Variability in diagnosis and management of acquired cold-induced urticaria.

Gernez Y, Sicherer SH, Wang J.

J Allergy Clin Immunol Pract. 2018 Jul - Aug;6(4):1396-1399. doi: 10.1016/j.jaip.2017.12.030. Epub 2018 Mar 9. No abstract available.


Autosomal Dominant Hyper-IgE Syndrome in the USIDNET Registry.

Gernez Y, Freeman AF, Holland SM, Garabedian E, Patel NC, Puck JM, Sullivan KE, Akhter J, Secord E, Chen K, Buckley R, Haddad E, Ochs HD, Fuleihan R, Routes J, Muskat M, Lugar P, Mancini J, Cunningham-Rundles C.

J Allergy Clin Immunol Pract. 2018 May - Jun;6(3):996-1001. doi: 10.1016/j.jaip.2017.06.041. Epub 2017 Sep 19.


Clinical and biological response to rituximab treatment in 3 patients with acquired C1-inhibitor deficiency.

Busse PJ, Gernez Y.

Ann Allergy Asthma Immunol. 2017 Oct;119(4):380-382. doi: 10.1016/j.anai.2017.07.032. Epub 2017 Aug 31. No abstract available.


Immunotherapy for Food Allergy: Are We There Yet?

Gernez Y, Nowak-Węgrzyn A.

J Allergy Clin Immunol Pract. 2017 Mar - Apr;5(2):250-272. doi: 10.1016/j.jaip.2016.12.004. Review. Erratum in: J Allergy Clin Immunol Pract. 2017 Jul - Aug;5(4):1167.


Hemoptysis in a Patient with Elevated Immunoglobulin E.

Gernez Y, Tsuang A, Smith TD, Shahjehan K, Hui Y, Maglione PJ, Cunningham-Rundles C.

J Allergy Clin Immunol Pract. 2016 Nov - Dec;4(6):1054-1058. doi: 10.1016/j.jaip.2016.08.003. Epub 2016 Sep 29.


Basophil activation test determination of CD63 combined with CD203c is not superior to CD203c alone in identifying allergic bronchopulmonary aspergillosis in cystic fibrosis.

Gernez Y, Waters J, Tirouvanziam R, Herzenberg L, Moss R.

J Allergy Clin Immunol. 2016 Oct;138(4):1195-1196. doi: 10.1016/j.jaci.2016.04.002. Epub 2016 Apr 22. No abstract available.


Earth Mover's Distance (EMD): A True Metric for Comparing Biomarker Expression Levels in Cell Populations.

Orlova DY, Zimmerman N, Meehan S, Meehan C, Waters J, Ghosn EE, Filatenkov A, Kolyagin GA, Gernez Y, Tsuda S, Moore W, Moss RB, Herzenberg LA, Walther G.

PLoS One. 2016 Mar 23;11(3):e0151859. doi: 10.1371/journal.pone.0151859. eCollection 2016.


Blood basophil activation is a reliable biomarker of allergic bronchopulmonary aspergillosis in cystic fibrosis.

Gernez Y, Waters J, Mirković B, Lavelle GM, Dunn CE, Davies ZA, Everson C, Tirouvanziam R, Silver E, Wallenstein S, Chotirmall SH, McElvaney NG, Herzenberg LA, Moss RB.

Eur Respir J. 2016 Jan;47(1):177-85. doi: 10.1183/13993003.01068-2015. Epub 2015 Nov 19. Erratum in: Eur Respir J. 2016 Jun;47(6):1892.


The basophil surface marker CD203c identifies Aspergillus species sensitization in patients with cystic fibrosis.

Mirković B, Lavelle GM, Azim AA, Helma K, Gargoum FS, Molloy K, Gernez Y, Dunne K, Renwick J, Murphy P, Moss RB, Greene CM, Gunaratnam C, Chotirmall SH, McElvaney NG.

J Allergy Clin Immunol. 2016 Feb;137(2):436-443.e9. doi: 10.1016/j.jaci.2015.07.045. Epub 2015 Sep 18.


Blood basophils from cystic fibrosis patients with allergic bronchopulmonary aspergillosis are primed and hyper-responsive to stimulation by aspergillus allergens.

Gernez Y, Dunn CE, Everson C, Mitsunaga E, Gudiputi L, Krasinska K, Davies ZA, Herzenberg LA, Tirouvanziam R, Moss RB.

J Cyst Fibros. 2012 Dec;11(6):502-10. doi: 10.1016/j.jcf.2012.04.008. Epub 2012 May 16.


Modulation of mTOR effector phosphoproteins in blood basophils from allergic patients.

Gernez Y, Tirouvanziam R, Reshamwala N, Yu G, Weldon BC, Galli SJ, Herzenberg LA, Nadeau KC.

J Clin Immunol. 2012 Jun;32(3):565-73. doi: 10.1007/s10875-012-9651-x. Epub 2012 Feb 21.


Immunophenotyping of peripheral eosinophils demonstrates activation in eosinophilic esophagitis.

Nguyen T, Gernez Y, Fuentebella J, Patel A, Tirouvanziam R, Reshamwala N, Bass D, Berquist WE, Cox KL, Kerner JA, Nadeau KC.

J Pediatr Gastroenterol Nutr. 2011 Jul;53(1):40-7. doi: 10.1097/MPG.0b013e318212647a.


Basophil CD203c levels are increased at baseline and can be used to monitor omalizumab treatment in subjects with nut allergy.

Gernez Y, Tirouvanziam R, Yu G, Ghosn EE, Reshamwala N, Nguyen T, Tsai M, Galli SJ, Herzenberg LA, Herzenberg LA, Nadeau KC.

Int Arch Allergy Immunol. 2011;154(4):318-27. doi: 10.1159/000321824. Epub 2010 Oct 25.


Increased HLA-DR expression on tissue eosinophils in eosinophilic esophagitis.

Patel AJ, Fuentebella J, Gernez Y, Nguyen T, Bass D, Berquist W, Cox K, Sibley E, Kerner J, Nadeau K.

J Pediatr Gastroenterol Nutr. 2010 Sep;51(3):290-4. doi: 10.1097/MPG.0b013e3181e083e7.


Neutrophils in chronic inflammatory airway diseases: can we target them and how?

Gernez Y, Tirouvanziam R, Chanez P.

Eur Respir J. 2010 Mar;35(3):467-9. doi: 10.1183/09031936.00186109. No abstract available.


Activation of critical, host-induced, metabolic and stress pathways marks neutrophil entry into cystic fibrosis lungs.

Makam M, Diaz D, Laval J, Gernez Y, Conrad CK, Dunn CE, Davies ZA, Moss RB, Herzenberg LA, Herzenberg LA, Tirouvanziam R.

Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5779-83. doi: 10.1073/pnas.0813410106. Epub 2009 Mar 17.


[A rare cause of stridor in a 59 year old woman in intensive care].

Gernez Y, Breen D, Peloni JM, Meric B, Dutau H.

Rev Mal Respir. 2008 Sep;25(7):871-4. French.


Profound functional and signaling changes in viable inflammatory neutrophils homing to cystic fibrosis airways.

Tirouvanziam R, Gernez Y, Conrad CK, Moss RB, Schrijver I, Dunn CE, Davies ZA, Herzenberg LA, Herzenberg LA.

Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4335-9. doi: 10.1073/pnas.0712386105. Epub 2008 Mar 11.


[Phospho-FACS: a powerful tool for exploring intracellular transduction cascades].

Gernez Y, Herzenberg LA, Herzenberg LA, Tirouvanziam R.

Rev Mal Respir. 2007 Oct;24(8):955-64. Review. French.


Altered phosphorylated signal transducer and activator of transcription profile of CD4+CD161+ T cells in asthma: modulation by allergic status and oral corticosteroids.

Gernez Y, Tirouvanziam R, Nguyen KD, Herzenberg LA, Krensky AM, Nadeau KC.

J Allergy Clin Immunol. 2007 Dec;120(6):1441-8. Epub 2007 Oct 24.


A contributive result of open-lung biopsy improves survival in acute respiratory distress syndrome patients.

Papazian L, Doddoli C, Chetaille B, Gernez Y, Thirion X, Roch A, Donati Y, Bonnety M, Zandotti C, Thomas P.

Crit Care Med. 2007 Mar;35(3):755-62.


[Hypersensitivity to carboplatin. An effect of generic drugs?].

Gernez Y, Barlesi F, Astoul P, Magnan A.

Rev Mal Respir. 2006 Jun;23(3 Pt 1):269-72. French.


[Acute respiratory distress syndrome following inhalation of barium sulfate].

Gernez Y, Barlési F, Doddoli C, Chetaille B, Forel JM, Astoul P, Papazian L.

Rev Mal Respir. 2005 Jun;22(3):477-80. French.


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