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Items: 1 to 50 of 291

1.

Rhinovirus C15 Induces Airway Hyperresponsiveness Via Calcium Mobilization in Airway Smooth Muscle.

Parikh V, Scala J, Patel R, Corbi C, Lo D, Bochkov YA, Kennedy JL, Kurten RC, Liggett SB, Gern JE, Koziol-White CJ.

Am J Respir Cell Mol Biol. 2019 Sep 18. doi: 10.1165/rcmb.2019-0004OC. [Epub ahead of print]

PMID:
31533004
2.

Rhinovirus Type in Severe Bronchiolitis and the Development of Asthma.

Bergroth E, Aakula M, Elenius V, Remes S, Piippo-Savolainen E, Korppi M, Piedra PA, Bochkov YA, Gern JE, Camargo CA Jr, Jartti T.

J Allergy Clin Immunol Pract. 2019 Sep 11. pii: S2213-2198(19)30768-8. doi: 10.1016/j.jaip.2019.08.043. [Epub ahead of print]

PMID:
31520837
3.

Respiratory health, allergies, and the farm environment: design, methods and enrollment in the observational Wisconsin Infant Study Cohort (WISC): a research proposal.

Seroogy CM, VanWormer JJ, Olson BF, Evans MD, Johnson T, Cole D, Barnes KL, Koepel TK, Dresen A, Meece J, Gangnon RE, Keifer MC, Bendixsen CG, Gern JE; Entire WISC Study Team.

BMC Res Notes. 2019 Jul 16;12(1):423. doi: 10.1186/s13104-019-4448-0.

4.

Cockroach allergen component analysis of children with or without asthma and rhinitis in an inner-city birth cohort.

Pomés A, Glesner J, Calatroni A, Visness CM, Wood RA, O'Connor GT, Kattan M, Bacharier LB, Wheatley LM, Gern JE, Busse WW; National Institute of Allergy and Infectious Diseases–funded Inner-City Asthma Consortium.

J Allergy Clin Immunol. 2019 Oct;144(4):935-944. doi: 10.1016/j.jaci.2019.05.036. Epub 2019 Jun 13.

PMID:
31201891
5.

Distinct nasal airway bacterial microbiotas differentially relate to exacerbation in pediatric patients with asthma.

McCauley K, Durack J, Valladares R, Fadrosh DW, Lin DL, Calatroni A, LeBeau PK, Tran HT, Fujimura KE, LaMere B, Merana G, Lynch K, Cohen RT, Pongracic J, Khurana Hershey GK, Kercsmar CM, Gill M, Liu AH, Kim H, Kattan M, Teach SJ, Togias A, Boushey HA, Gern JE, Jackson DJ, Lynch SV; National Institute of Allergy and Infectious Diseases–sponsored Inner-City Asthma Consortium.

J Allergy Clin Immunol. 2019 Jun 13. pii: S0091-6749(19)30758-4. doi: 10.1016/j.jaci.2019.05.035. [Epub ahead of print]

PMID:
31201890
6.

The Children's Respiratory and Environmental Workgroup (CREW) birth cohort consortium: design, methods, and study population.

Gern JE, Jackson DJ, Lemanske RF Jr, Seroogy CM, Tachinardi U, Craven M, Hwang SY, Hamilton CM, Huggins W, O'Connor GT, Gold DR, Miller R, Kattan M, Johnson CC, Ownby D, Zoratti EM, Wood RA, Visness CM, Martinez F, Wright A, Lynch S, Ober C, Khurana Hershey GK, Ryan P, Hartert T, Bacharier LB.

Respir Res. 2019 Jun 10;20(1):115. doi: 10.1186/s12931-019-1088-9.

7.

Asthma as an outcome: Exploring multiple definitions of asthma across birth cohorts in the Environmental influences on Child Health Outcomes Children's Respiratory and Environmental Workgroup.

Visness CM, Gebretsadik T, Jackson DJ, Biagini Myers J, Havstad S, Lemanske RF Jr, Hartert TV, Khurana Hershey GK, Zoratti EM, Martin LJ, Miller R, Gold DR, Wright A, Stern DA, Gern JE, Johnson CC; Children's Respiratory and Environmental Workgroup.

J Allergy Clin Immunol. 2019 Sep;144(3):866-869.e4. doi: 10.1016/j.jaci.2019.05.025. Epub 2019 Jun 1. No abstract available.

PMID:
31163174
8.

The association of allergic sensitization patterns in early childhood with disease manifestations and immunological reactivity at 10 years of age.

Schulten V, Frazier A, Calatroni A, Kattan M, Bacharier LB, O'Connor GT, Sandel MT, Wood RA, Wheatley LM, Togias A, Visness CM, Dresen A, Gern JE, Sette A.

Clin Exp Allergy. 2019 Aug;49(8):1087-1094. doi: 10.1111/cea.13406. Epub 2019 May 29.

PMID:
31046157
9.

Reply.

Altman MC, Gern JE.

J Allergy Clin Immunol. 2019 Jun;143(6):2334-2335. doi: 10.1016/j.jaci.2019.03.006. Epub 2019 Apr 9. No abstract available.

PMID:
30979657
10.

Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children.

Altman MC, Gill MA, Whalen E, Babineau DC, Shao B, Liu AH, Jepson B, Gruchalla RS, O'Connor GT, Pongracic JA, Kercsmar CM, Khurana Hershey GK, Zoratti EM, Johnson CC, Teach SJ, Kattan M, Bacharier LB, Beigelman A, Sigelman SM, Presnell S, Gern JE, Gergen PJ, Wheatley LM, Togias A, Busse WW, Jackson DJ.

Nat Immunol. 2019 May;20(5):637-651. doi: 10.1038/s41590-019-0347-8. Epub 2019 Apr 8.

11.

Association of Rhinovirus C Bronchiolitis and Immunoglobulin E Sensitization During Infancy With Development of Recurrent Wheeze.

Hasegawa K, Mansbach JM, Bochkov YA, Gern JE, Piedra PA, Bauer CS, Teach SJ, Wu S, Sullivan AF, Camargo CA Jr.

JAMA Pediatr. 2019 Jun 1;173(6):544-552. doi: 10.1001/jamapediatrics.2019.0384.

PMID:
30933255
12.

CDHR3 Asthma-Risk Genotype Affects Susceptibility of Airway Epithelium to Rhinovirus C Infections.

Basnet S, Bochkov YA, Brockman-Schneider RA, Kuipers I, Aesif SW, Jackson DJ, Lemanske RF Jr, Ober C, Palmenberg AC, Gern JE.

Am J Respir Cell Mol Biol. 2019 Oct;61(4):450-458. doi: 10.1165/rcmb.2018-0220OC.

PMID:
30916989
13.

Simultaneous outbreaks of respiratory disease in wild chimpanzees caused by distinct viruses of human origin.

Negrey JD, Reddy RB, Scully EJ, Phillips-Garcia S, Owens LA, Langergraber KE, Mitani JC, Emery Thompson M, Wrangham RW, Muller MN, Otali E, Machanda Z, Hyeroba D, Grindle KA, Pappas TE, Palmenberg AC, Gern JE, Goldberg TL.

Emerg Microbes Infect. 2019;8(1):139-149. doi: 10.1080/22221751.2018.1563456.

14.

Rhinoviruses and Their Receptors.

Basnet S, Palmenberg AC, Gern JE.

Chest. 2019 May;155(5):1018-1025. doi: 10.1016/j.chest.2018.12.012. Epub 2019 Jan 17. Review.

PMID:
30659817
15.

Association between rhinovirus species and nasopharyngeal microbiota in infants with severe bronchiolitis.

Toivonen L, Camargo CA Jr, Gern JE, Bochkov YA, Mansbach JM, Piedra PA, Hasegawa K.

J Allergy Clin Immunol. 2019 May;143(5):1925-1928.e7. doi: 10.1016/j.jaci.2018.12.1004. Epub 2019 Jan 14. No abstract available.

PMID:
30654045
16.

Report from the National Institute of Allergy and Infectious Diseases workshop on "Atopic dermatitis and the atopic march: Mechanisms and interventions".

Davidson WF, Leung DYM, Beck LA, Berin CM, Boguniewicz M, Busse WW, Chatila TA, Geha RS, Gern JE, Guttman-Yassky E, Irvine AD, Kim BS, Kong HH, Lack G, Nadeau KC, Schwaninger J, Simpson A, Simpson EL, Spergel JM, Togias A, Wahn U, Wood RA, Woodfolk JA, Ziegler SF, Plaut M.

J Allergy Clin Immunol. 2019 Mar;143(3):894-913. doi: 10.1016/j.jaci.2019.01.003. Epub 2019 Jan 9.

PMID:
30639346
17.

Competition among Nasal Bacteria Suggests a Role for Siderophore-Mediated Interactions in Shaping the Human Nasal Microbiota.

Stubbendieck RM, May DS, Chevrette MG, Temkin MI, Wendt-Pienkowski E, Cagnazzo J, Carlson CM, Gern JE, Currie CR.

Appl Environ Microbiol. 2019 May 2;85(10). pii: e02406-18. doi: 10.1128/AEM.02406-18. Print 2019 May 15.

PMID:
30578265
18.

Emerging concepts and challenges in implementing the exposome paradigm in allergic diseases and asthma: a Practall document.

Agache I, Miller R, Gern JE, Hellings PW, Jutel M, Muraro A, Phipatanakul W, Quirce S, Peden D.

Allergy. 2019 Mar;74(3):449-463. doi: 10.1111/all.13690. Epub 2018 Dec 27.

PMID:
30515837
19.

TLR-7 Stress Signaling in Differentiating and Mature Eosinophils Is Mediated by the Prolyl Isomerase Pin1.

Shen ZJ, Hu J, Kashi V, Bochkov YA, Gern JE, Malter JS.

J Immunol. 2018 Dec 15;201(12):3503-3513. doi: 10.4049/jimmunol.1800881. Epub 2018 Nov 5.

PMID:
30397031
20.

Development of a Rhinovirus Inoculum Using a Reverse Genetics Approach.

Gern JE, Lee WM, Swenson CA, Nakagome K, Lee I, Wolff M, Grindle K, Sigelman S, Liggett SB, Togias A, Evans M, Denlinger L, Gangnon R, Bochkov YA, Crisafi G.

J Infect Dis. 2019 Jun 19;220(2):187-194. doi: 10.1093/infdis/jiy629.

PMID:
30383246
21.

Trajectories of childhood immune development and respiratory health relevant to asthma and allergy.

Tang HH, Teo SM, Belgrave DC, Evans MD, Jackson DJ, Brozynska M, Kusel MM, Johnston SL, Gern JE, Lemanske RF, Simpson A, Custovic A, Sly PD, Holt PG, Holt KE, Inouye M.

Elife. 2018 Oct 15;7. pii: e35856. doi: 10.7554/eLife.35856.

22.

Asthma is associated with carotid arterial injury in children: The Childhood Origins of Asthma (COAST) Cohort.

Tattersall MC, Evans MD, Korcarz CE, Mitchell C, Anderson E, DaSilva DF, Salazar LP, Gern JE, Jackson DJ, Lemanske RF Jr, Stein JH.

PLoS One. 2018 Sep 27;13(9):e0204708. doi: 10.1371/journal.pone.0204708. eCollection 2018.

23.

Rhinitis in children and adolescents with asthma: Ubiquitous, difficult to control, and associated with asthma outcomes.

Togias A, Gergen PJ, Hu JW, Babineau DC, Wood RA, Cohen RT, Makhija MM, Khurana Hershey GK, Kercsmar CM, Gruchalla RS, Liu AH, Wang E, Kim H, Lamm CI, Bacharier LB, Pillai D, Sigelman SM, Gern JE, Busse WW.

J Allergy Clin Immunol. 2019 Mar;143(3):1003-1011.e10. doi: 10.1016/j.jaci.2018.07.041. Epub 2018 Sep 11.

PMID:
30213627
24.

Airway Microbiota Dynamics Uncover a Critical Window for Interplay of Pathogenic Bacteria and Allergy in Childhood Respiratory Disease.

Teo SM, Tang HHF, Mok D, Judd LM, Watts SC, Pham K, Holt BJ, Kusel M, Serralha M, Troy N, Bochkov YA, Grindle K, Lemanske RF Jr, Johnston SL, Gern JE, Sly PD, Holt PG, Holt KE, Inouye M.

Cell Host Microbe. 2018 Sep 12;24(3):341-352.e5. doi: 10.1016/j.chom.2018.08.005.

25.

Pulmonary function and bronchial reactivity 4 years after the first virus-induced wheezing.

Leino A, Lukkarinen M, Turunen R, Vuorinen T, Söderlund-Venermo M, Vahlberg T, Camargo CA Jr, Bochkov YA, Gern JE, Jartti T.

Allergy. 2019 Mar;74(3):518-526. doi: 10.1111/all.13593. Epub 2018 Oct 8.

PMID:
30144084
26.

Longitudinal Phenotypes of Respiratory Health in a High-Risk Urban Birth Cohort.

Bacharier LB, Beigelman A, Calatroni A, Jackson DJ, Gergen PJ, O'Connor GT, Kattan M, Wood RA, Sandel MT, Lynch SV, Fujimura KE, Fadrosh DW, Santee CA, Boushey H, Visness CM, Gern JE; NIAID sponsored Inner-City Asthma Consortium.

Am J Respir Crit Care Med. 2019 Jan 1;199(1):71-82. doi: 10.1164/rccm.201801-0190OC.

PMID:
30079758
27.

Rhinovirus Species in Children With Severe Bronchiolitis: Multicenter Cohort Studies in the United States and Finland.

Hasegawa K, Jartti T, Bochkov YA, Gern JE, Mansbach JM, Piedra PA, Toivonen L, Camargo CA Jr.

Pediatr Infect Dis J. 2019 Mar;38(3):e59-e62. doi: 10.1097/INF.0000000000002141.

PMID:
30001231
28.

Rhinovirus is the most common virus and rhinovirus-C is the most common species in paediatric intensive care respiratory admissions.

Cox DW, Khoo SK, Zhang G, Lindsay K, Keil AD, Knight G, Gern JE, Laing IA, Bizzintino J, Le Souëf PN.

Eur Respir J. 2018 Aug 9;52(2). pii: 1800207. doi: 10.1183/13993003.00207-2018. Print 2018 Aug. No abstract available.

29.

Reply.

Altman MC, Gern JE.

J Allergy Clin Immunol. 2018 Aug;142(2):713. doi: 10.1016/j.jaci.2018.04.035. Epub 2018 Jun 23. No abstract available.

PMID:
29945814
30.

Glycation of whey protein with dextrans of different molar mass: Effect on immunoglobulin E-binding capacity with blood sera obtained from patients with cow milk protein allergy.

Xu L, Gong Y, Gern JE, Ikeda S, Lucey JA.

J Dairy Sci. 2018 Aug;101(8):6823-6834. doi: 10.3168/jds.2017-14338. Epub 2018 May 16.

31.

Global DNA methylation changes spanning puberty are near predicted estrogen-responsive genes and enriched for genes involved in endocrine and immune processes.

Thompson EE, Nicodemus-Johnson J, Kim KW, Gern JE, Jackson DJ, Lemanske RF, Ober C.

Clin Epigenetics. 2018 May 9;10:62. doi: 10.1186/s13148-018-0491-2. eCollection 2018.

32.

A new model of wheezing severity in young children using the validated ISAAC wheezing module: A latent variable approach with validation in independent cohorts.

Brunwasser SM, Gebretsadik T, Gold DR, Turi KN, Stone CA Jr, Datta S, Gern JE, Hartert TV.

PLoS One. 2018 Apr 17;13(4):e0194739. doi: 10.1371/journal.pone.0194739. eCollection 2018.

33.

Allergen-induced activation of natural killer cells represents an early-life immune response in the development of allergic asthma.

Altman MC, Whalen E, Togias A, O'Connor GT, Bacharier LB, Bloomberg GR, Kattan M, Wood RA, Presnell S, LeBeau P, Jaffee K, Visness CM, Busse WW, Gern JE.

J Allergy Clin Immunol. 2018 Dec;142(6):1856-1866. doi: 10.1016/j.jaci.2018.02.019. Epub 2018 Mar 5.

PMID:
29518416
34.

Spirometry and Impulse Oscillometry in Preschool Children: Acceptability and Relationship to Maternal Smoking in Pregnancy.

Kattan M, Bacharier LB, O'Connor GT, Cohen R, Sorkness RL, Morgan W, Gergen PJ, Jaffee KF, Visness CM, Wood RA, Bloomberg GR, Doyle S, Burton R, Gern JE.

J Allergy Clin Immunol Pract. 2018 Sep - Oct;6(5):1596-1603.e6. doi: 10.1016/j.jaip.2017.12.028. Epub 2018 Feb 13.

35.

Development of Asthma in Inner-City Children: Possible Roles of MAIT Cells and Variation in the Home Environment.

Chandra S, Wingender G, Greenbaum JA, Khurana A, Gholami AM, Ganesan AP, Rosenbach M, Jaffee K, Gern JE, Wood R, O'Connor G, Sandel M, Kattan M, Bacharier L, Togias A, Horner AA, Kronenberg M.

J Immunol. 2018 Mar 15;200(6):1995-2003. doi: 10.4049/jimmunol.1701525. Epub 2018 Feb 5.

36.

Lethal Respiratory Disease Associated with Human Rhinovirus C in Wild Chimpanzees, Uganda, 2013.

Scully EJ, Basnet S, Wrangham RW, Muller MN, Otali E, Hyeroba D, Grindle KA, Pappas TE, Thompson ME, Machanda Z, Watters KE, Palmenberg AC, Gern JE, Goldberg TL.

Emerg Infect Dis. 2018 Feb;24(2):267-274. doi: 10.3201/eid2402.170778.

37.

Viral Infections and Associated Factors That Promote Acute Exacerbations of Asthma.

Kim CK, Callaway Z, Gern JE.

Allergy Asthma Immunol Res. 2018 Jan;10(1):12-17. doi: 10.4168/aair.2018.10.1.12. Review.

38.

Microbial volatile communication in human organotypic lung models.

Barkal LJ, Procknow CL, Álvarez-García YR, Niu M, Jiménez-Torres JA, Brockman-Schneider RA, Gern JE, Denlinger LC, Theberge AB, Keller NP, Berthier E, Beebe DJ.

Nat Commun. 2017 Nov 24;8(1):1770. doi: 10.1038/s41467-017-01985-4.

39.

Cadherin-related Family Member 3 Genetics and Rhinovirus C Respiratory Illnesses.

Bønnelykke K, Coleman AT, Evans MD, Thorsen J, Waage J, Vissing NH, Carlsson CJ, Stokholm J, Chawes BL, Jessen LE, Fischer TK, Bochkov YA, Ober C, Lemanske RF Jr, Jackson DJ, Gern JE, Bisgaard H.

Am J Respir Crit Care Med. 2018 Mar 1;197(5):589-594. doi: 10.1164/rccm.201705-1021OC.

40.
41.

Association of rhinovirus species with common cold and asthma symptoms and bacterial pathogens.

Bashir H, Grindle K, Vrtis R, Vang F, Kang T, Salazar L, Anderson E, Pappas T, Gangnon R, Evans MD, Jackson DJ, Lemanske RF Jr, Bochkov YA, Gern JE.

J Allergy Clin Immunol. 2018 Feb;141(2):822-824.e9. doi: 10.1016/j.jaci.2017.09.027. Epub 2017 Oct 27. No abstract available.

42.

Role of viral infections in the development and exacerbation of asthma in children.

Jartti T, Gern JE.

J Allergy Clin Immunol. 2017 Oct;140(4):895-906. doi: 10.1016/j.jaci.2017.08.003. Review.

PMID:
28987219
43.

Early-life home environment and risk of asthma among inner-city children.

O'Connor GT, Lynch SV, Bloomberg GR, Kattan M, Wood RA, Gergen PJ, Jaffee KF, Calatroni A, Bacharier LB, Beigelman A, Sandel MT, Johnson CC, Faruqi A, Santee C, Fujimura KE, Fadrosh D, Boushey H, Visness CM, Gern JE.

J Allergy Clin Immunol. 2018 Apr;141(4):1468-1475. doi: 10.1016/j.jaci.2017.06.040. Epub 2017 Sep 19.

44.

Screen Time Engagement Is Increased in Urban Children With Asthma.

Rota AP, Bacharier LB, Jaffee K, Visness CM, Kattan M, O'Connor GT, Wood RA, Gergen PJ, Gern JE, Bloomberg GR.

Clin Pediatr (Phila). 2017 Oct;56(11):1048-1053. doi: 10.1177/0009922817698801. Epub 2017 Mar 20.

45.

Enhanced plasmacytoid dendritic cell antiviral responses after omalizumab.

Gill MA, Liu AH, Calatroni A, Krouse RZ, Shao B, Schiltz A, Gern JE, Togias A, Busse WW.

J Allergy Clin Immunol. 2018 May;141(5):1735-1743.e9. doi: 10.1016/j.jaci.2017.07.035. Epub 2017 Sep 1.

46.

Farm exposure in early childhood is associated with a lower risk of severe respiratory illnesses.

Ludka-Gaulke T, Ghera P, Waring SC, Keifer M, Seroogy C, Gern JE, Kirkhorn S.

J Allergy Clin Immunol. 2018 Jan;141(1):454-456.e4. doi: 10.1016/j.jaci.2017.07.032. Epub 2017 Sep 21. No abstract available.

47.

Toll-like receptor 3 blockade in rhinovirus-induced experimental asthma exacerbations: A randomized controlled study.

Silkoff PE, Flavin S, Gordon R, Loza MJ, Sterk PJ, Lutter R, Diamant Z, Turner RB, Lipworth BJ, Proud D, Singh D, Eich A, Backer V, Gern JE, Herzmann C, Halperin SA, Mensinga TT, Del Vecchio AM, Branigan P, San Mateo L, Baribaud F, Barnathan ES, Johnston SL.

J Allergy Clin Immunol. 2018 Apr;141(4):1220-1230. doi: 10.1016/j.jaci.2017.06.027. Epub 2017 Jul 20.

48.

Endotypes of difficult-to-control asthma in inner-city African American children.

Brown KR, Krouse RZ, Calatroni A, Visness CM, Sivaprasad U, Kercsmar CM, Matsui EC, West JB, Makhija MM, Gill MA, Kim H, Kattan M, Pillai D, Gern JE, Busse WW, Togias A, Liu AH, Khurana Hershey GK.

PLoS One. 2017 Jul 7;12(7):e0180778. doi: 10.1371/journal.pone.0180778. eCollection 2017.

49.

Picornavectors. Viruses That Spread Bacteria.

Gern JE.

Am J Respir Crit Care Med. 2017 Nov 1;196(9):1095-1096. doi: 10.1164/rccm.201706-1073ED. No abstract available.

PMID:
28628339
50.

Effects of Omalizumab on Rhinovirus Infections, Illnesses, and Exacerbations of Asthma.

Esquivel A, Busse WW, Calatroni A, Togias AG, Grindle KG, Bochkov YA, Gruchalla RS, Kattan M, Kercsmar CM, Khurana Hershey G, Kim H, Lebeau P, Liu AH, Szefler SJ, Teach SJ, West JB, Wildfire J, Pongracic JA, Gern JE.

Am J Respir Crit Care Med. 2017 Oct 15;196(8):985-992. doi: 10.1164/rccm.201701-0120OC.

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