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Items: 1 to 50 of 51

1.

YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics.

Fan PD, Narzisi G, Jayaprakash AD, Venturini E, Robine N, Smibert P, Germer S, Yu HA, Jordan EJ, Paik PK, Janjigian YY, Chaft JE, Wang L, Jungbluth AA, Middha S, Spraggon L, Qiao H, Lovly CM, Kris MG, Riely GJ, Politi K, Varmus H, Ladanyi M.

Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):E6030-E6038. doi: 10.1073/pnas.1717782115. Epub 2018 Jun 6.

2.

Whole-Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma.

Mak ACY, White MJ, Eckalbar WL, Szpiech ZA, Oh SS, Pino-Yanes M, Hu D, Goddard P, Huntsman S, Galanter J, Wu AC, Himes BE, Germer S, Vogel JM, Bunting KL, Eng C, Salazar S, Keys KL, Liberto J, Nuckton TJ, Nguyen TA, Torgerson DG, Kwok PY, Levin AM, Celedón JC, Forno E, Hakonarson H, Sleiman PM, Dahlin A, Tantisira KG, Weiss ST, Serebrisky D, Brigino-Buenaventura E, Farber HJ, Meade K, Lenoir MA, Avila PC, Sen S, Thyne SM, Rodriguez-Cintron W, Winkler CA, Moreno-Estrada A, Sandoval K, Rodriguez-Santana JR, Kumar R, Williams LK, Ahituv N, Ziv E, Seibold MA, Darnell RB, Zaitlen N, Hernandez RD, Burchard EG; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium.

Am J Respir Crit Care Med. 2018 Jun 15;197(12):1552-1564. doi: 10.1164/rccm.201712-2529OC.

PMID:
29509491
3.

Encapsulating anthocyanins from Hibiscus sabdariffa L. calyces by ionic gelation: Pigment stability during storage of microparticles.

de Moura SCSR, Berling CL, Germer SPM, Alvim ID, Hubinger MD.

Food Chem. 2018 Feb 15;241:317-327. doi: 10.1016/j.foodchem.2017.08.095. Epub 2017 Aug 31.

PMID:
28958534
4.

Quantitative low-energy ion beam characterization by beam profiling and imaging via scintillation screens.

Germer S, Pietag F, Polak J, Arnold T.

Rev Sci Instrum. 2016 Nov;87(11):113301.

PMID:
27910594
5.

Evaluation of acute-to-chronic ratios of fish and Daphnia to predict acceptable no-effect levels.

May M, Drost W, Germer S, Juffernholz T, Hahn S.

Environ Sci Eur. 2016;28(1):16. Epub 2016 May 12.

6.

Differential burden of rare protein truncating variants in Alzheimer's disease patients compared to centenarians.

Freudenberg-Hua Y, Li W, Abhyankar A, Vacic V, Cortes V, Ben-Avraham D, Koppel J, Greenwald B, Germer S; T2D-GENES Consortium, Darnell RB, Barzilai N, Freudenberg J, Atzmon G, Davies P.

Hum Mol Genet. 2016 Jul 15;25(14):3096-3105. Epub 2016 Jun 3.

7.

Evaluation of the integrated testing strategy for PNEC derivation under REACH.

May M, Drost W, Germer S, Juffernholz T, Hahn S.

Regul Toxicol Pharmacol. 2016 Jul;78:59-65. doi: 10.1016/j.yrtph.2016.04.004. Epub 2016 Apr 19.

PMID:
27103318
8.

Features of Circulating Parainfluenza Virus Required for Growth in Human Airway.

Palermo LM, Uppal M, Skrabanek L, Zumbo P, Germer S, Toussaint NC, Rima BK, Huey D, Niewiesk S, Porotto M, Moscona A.

MBio. 2016 Mar 15;7(2):e00235. doi: 10.1128/mBio.00235-16.

9.

Disease variants in genomes of 44 centenarians.

Freudenberg-Hua Y, Freudenberg J, Vacic V, Abhyankar A, Emde AK, Ben-Avraham D, Barzilai N, Oschwald D, Christen E, Koppel J, Greenwald B, Darnell RB, Germer S, Atzmon G, Davies P.

Mol Genet Genomic Med. 2014 Sep;2(5):438-50. doi: 10.1002/mgg3.86. Epub 2014 Jun 15.

10.

Detection of a recurrent DNAJB1-PRKACA chimeric transcript in fibrolamellar hepatocellular carcinoma.

Honeyman JN, Simon EP, Robine N, Chiaroni-Clarke R, Darcy DG, Lim II, Gleason CE, Murphy JM, Rosenberg BR, Teegan L, Takacs CN, Botero S, Belote R, Germer S, Emde AK, Vacic V, Bhanot U, LaQuaglia MP, Simon SM.

Science. 2014 Feb 28;343(6174):1010-4. doi: 10.1126/science.1249484.

11.

IL-6 pathway-driven investigation of response to IL-6 receptor inhibition in rheumatoid arthritis.

Wang J, Platt A, Upmanyu R, Germer S, Lei G, Rabe C, Benayed R, Kenwright A, Hemmings A, Martin M, Harari O.

BMJ Open. 2013 Aug 19;3(8):e003199. doi: 10.1136/bmjopen-2013-003199.

12.

Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis.

Krintel SB, Palermo G, Johansen JS, Germer S, Essioux L, Benayed R, Badi L, Ostergaard M, Hetland ML.

Pharmacogenet Genomics. 2012 Aug;22(8):577-89. doi: 10.1097/FPC.0b013e3283544043.

PMID:
22569225
13.

Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident coronary heart disease in a Hong Kong Chinese population.

Ho JS, Germer S, Tam CH, So WY, Martin M, Ma RC, Chan JC, Ng MC.

Diabetes Res Clin Pract. 2012 Sep;97(3):483-91. doi: 10.1016/j.diabres.2012.03.012. Epub 2012 Apr 18.

PMID:
22515931
14.

Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis.

Wang J, Bansal AT, Martin M, Germer S, Benayed R, Essioux L, Lee JS, Begovich A, Hemmings A, Kenwright A, Taylor KE, Upmanyu R, Cutler P, Harari O, Marchini J, Criswell LA, Platt A.

Pharmacogenomics J. 2013 Jun;13(3):235-41. doi: 10.1038/tpj.2012.8. Epub 2012 Apr 10.

PMID:
22491018
15.

Effect of IL28B genotype on early viral kinetics during interferon-free treatment of patients with chronic hepatitis C.

Chu TW, Kulkarni R, Gane EJ, Roberts SK, Stedman C, Angus PW, Ritchie B, Lu XY, Ipe D, Lopatin U, Germer S, Iglesias VA, Elston R, Smith PF, Shulman NS.

Gastroenterology. 2012 Apr;142(4):790-5. doi: 10.1053/j.gastro.2011.12.057. Epub 2012 Jan 13.

PMID:
22248659
16.

Resistance to selective BRAF inhibition can be mediated by modest upstream pathway activation.

Su F, Bradley WD, Wang Q, Yang H, Xu L, Higgins B, Kolinsky K, Packman K, Kim MJ, Trunzer K, Lee RJ, Schostack K, Carter J, Albert T, Germer S, Rosinski J, Martin M, Simcox ME, Lestini B, Heimbrook D, Bollag G.

Cancer Res. 2012 Feb 15;72(4):969-78. doi: 10.1158/0008-5472.CAN-11-1875. Epub 2011 Dec 28.

17.

Genetic variation in UGT1A1 typical of Gilbert syndrome is associated with unconjugated hyperbilirubinemia in patients receiving tocilizumab.

Lee JS, Wang J, Martin M, Germer S, Kenwright A, Benayed R, Spleiss O, Platt A, Pilson R, Hemmings A, Weinblatt ME, Kaplowitz N, Krasnow J.

Pharmacogenet Genomics. 2011 Jul;21(7):365-74. doi: 10.1097/FPC.0b013e32834592fe.

PMID:
21412181
18.

Gene variation of the transient receptor potential cation channel, subfamily M, members 6 (TRPM6) and 7 (TRPM7), and type 2 diabetes mellitus: a case-control study.

Romero JR, Castonguay AJ, Barton NS, Germer S, Martin M, Zee RY.

Transl Res. 2010 Oct;156(4):235-41. doi: 10.1016/j.trsl.2010.07.001. Epub 2010 Aug 7.

PMID:
20875900
19.

Common polymorphisms in MTNR1B, G6PC2 and GCK are associated with increased fasting plasma glucose and impaired beta-cell function in Chinese subjects.

Tam CH, Ho JS, Wang Y, Lee HM, Lam VK, Germer S, Martin M, So WY, Ma RC, Chan JC, Ng MC.

PLoS One. 2010 Jul 8;5(7):e11428. doi: 10.1371/journal.pone.0011428.

20.

Gene variation of the transient receptor potential cation channel, subfamily M, member 2 (TRPM2) and type 2 diabetes mellitus: A case-control study.

Romero JR, Germer S, Castonguay AJ, Barton NS, Martin M, Zee RY.

Clin Chim Acta. 2010 Oct 9;411(19-20):1437-40. doi: 10.1016/j.cca.2010.05.036. Epub 2010 Jun 1.

PMID:
20515676
21.

Mean leukocyte telomere length shortening and type 2 diabetes mellitus: a case-control study.

Zee RY, Castonguay AJ, Barton NS, Germer S, Martin M.

Transl Res. 2010 Apr;155(4):166-9. doi: 10.1016/j.trsl.2009.09.012. Epub 2009 Oct 22.

PMID:
20303464
22.

Benzopyranones and their sulfate esters from Pelargonium sidoides.

Hauer H, Germer S, Elsässer J, Ritter T.

Planta Med. 2010 Mar;76(4):350-2. doi: 10.1055/s-0029-1186167. Epub 2009 Oct 6.

PMID:
19809972
23.

Association of shorter mean telomere length with risk of incident myocardial infarction: a prospective, nested case-control approach.

Zee RY, Michaud SE, Germer S, Ridker PM.

Clin Chim Acta. 2009 May;403(1-2):139-41. doi: 10.1016/j.cca.2009.02.004. Epub 2009 Feb 13.

24.

Interaction effect of genetic polymorphisms in glucokinase (GCK) and glucokinase regulatory protein (GCKR) on metabolic traits in healthy Chinese adults and adolescents.

Tam CH, Ma RC, So WY, Wang Y, Lam VK, Germer S, Martin M, Chan JC, Ng MC.

Diabetes. 2009 Mar;58(3):765-9. doi: 10.2337/db08-1277. Epub 2008 Dec 10.

25.

Polymorphisms in advanced glycosylation end product-specific receptor (AGER) gene, insulin resistance, and type 2 diabetes mellitus.

Goulart AC, Germer S, Rexrode KM, Martin M, Zee RY.

Clin Chim Acta. 2008 Dec;398(1-2):95-8. doi: 10.1016/j.cca.2008.08.020. Epub 2008 Sep 3.

PMID:
18796298
26.

Chromosome translocations in workers exposed to benzene.

McHale CM, Lan Q, Corso C, Li G, Zhang L, Vermeulen R, Curry JD, Shen M, Turakulov R, Higuchi R, Germer S, Yin S, Rothman N, Smith MT.

J Natl Cancer Inst Monogr. 2008;(39):74-7. doi: 10.1093/jncimonographs/lgn010.

PMID:
18648008
27.

A 28-day oral dose toxicity study in Wistar rats enhanced to detect endocrine effects of decabromodiphenyl ether (decaBDE).

Van der Ven LT, van de Kuil T, Leonards PE, Slob W, Cantón RF, Germer S, Visser TJ, Litens S, Håkansson H, Schrenk D, van den Berg M, Piersma AH, Vos JG, Opperhuizen A.

Toxicol Lett. 2008 Jun 10;179(1):6-14. doi: 10.1016/j.toxlet.2008.03.003. Epub 2008 Mar 12.

PMID:
18495385
28.

A detailed view on the constituents of EPs 7630.

Schoetz K, Erdelmeier C, Germer S, Hauer H.

Planta Med. 2008 May;74(6):667-74. doi: 10.1055/s-2008-1074515. Epub 2008 Apr 30.

PMID:
18449848
29.

A 28-day oral dose toxicity study enhanced to detect endocrine effects of a purified technical pentabromodiphenyl ether (pentaBDE) mixture in Wistar rats.

van der Ven LT, van de Kuil T, Verhoef A, Leonards PE, Slob W, Cantón RF, Germer S, Hamers T, Visser TJ, Litens S, Håkansson H, Fery Y, Schrenk D, van den Berg M, Piersma AH, Vos JG.

Toxicology. 2008 Mar 12;245(1-2):109-22. doi: 10.1016/j.tox.2007.12.016. Epub 2007 Dec 27. Erratum in: Toxicology. 2011 Feb 27;280(3):178. Dosage error in article text.

PMID:
18243468
30.

C-reactive protein gene variation and type 2 diabetes mellitus: a case-control study.

Zee RY, Germer S, Thomas A, Raji A, Rhees B, Ridker PM, Lindpaintner K, Williams GH, Nathan DM, Martin M.

Atherosclerosis. 2008 Apr;197(2):931-6. Epub 2007 Sep 27.

PMID:
17900590
31.

High-throughput SNP genotyping by single-tube PCR with Tm-shift primers.

Wang J, Chuang K, Ahluwalia M, Patel S, Umblas N, Mirel D, Higuchi R, Germer S.

Biotechniques. 2005 Dec;39(6):885-93.

32.

Subacute effects of the brominated flame retardants hexabromocyclododecane and tetrabromobisphenol A on hepatic cytochrome P450 levels in rats.

Germer S, Piersma AH, van der Ven L, Kamyschnikow A, Fery Y, Schmitz HJ, Schrenk D.

Toxicology. 2006 Feb 1;218(2-3):229-36. Epub 2005 Dec 2.

PMID:
16325980
33.

High-throughput association testing on DNA pools to identify genetic variants that confer susceptibility to acute myeloid leukemia.

Rollinson S, Allan JM, Law GR, Roddam PL, Smith MT, Skibola C, Smith AG, Forrest MS, Sibley K, Higuchi R, Germer S, Morgan GJ.

Cancer Epidemiol Biomarkers Prev. 2004 May;13(5):795-800.

34.

Homogeneous allele-specific PCR in SNP genotyping.

Germer S, Higuchi R.

Methods Mol Biol. 2003;212:197-214. No abstract available.

PMID:
12491912
35.

Kinetic polymerase chain reaction on pooled DNA: a high-throughput, high-efficiency alternative in genetic epidemiological studies.

Chen J, Germer S, Higuchi R, Berkowitz G, Godbold J, Wetmur JG.

Cancer Epidemiol Biomarkers Prev. 2002 Jan;11(1):131-6.

36.

Thr40 and Met122 are new partial loss-of-function natural mutations of the human melanocortin 1 receptor.

Jiménez-Cervantes C, Germer S, González P, Sánchez J, Sánchez CO, García-Borrón JC.

FEBS Lett. 2001 Nov 9;508(1):44-8.

37.

In silico mapping of complex disease-related traits in mice.

Grupe A, Germer S, Usuka J, Aud D, Belknap JK, Klein RF, Ahluwalia MK, Higuchi R, Peltz G.

Science. 2001 Jun 8;292(5523):1915-8.

38.

Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma.

Karp CL, Grupe A, Schadt E, Ewart SL, Keane-Moore M, Cuomo PJ, Köhl J, Wahl L, Kuperman D, Germer S, Aud D, Peltz G, Wills-Karp M.

Nat Immunol. 2000 Sep;1(3):221-6.

PMID:
10973279
39.

High-throughput SNP allele-frequency determination in pooled DNA samples by kinetic PCR.

Germer S, Holland MJ, Higuchi R.

Genome Res. 2000 Feb;10(2):258-66.

40.

Single-tube genotyping without oligonucleotide probes.

Germer S, Higuchi R.

Genome Res. 1999 Jan;9(1):72-8.

41.

Do diabetics remember all they have been taught? A survey of knowledge of insulin-dependent diabetics.

Germer S, Campbell IW, Smith AW, Sutherland JD, Jones IG.

Diabet Med. 1986 Jul-Aug;3(4):343-5.

PMID:
2949924
42.

Hyponatraemia associated with pneumonia or bacterial meningitis.

Shann F, Germer S.

Arch Dis Child. 1985 Oct;60(10):963-6.

43.

Home-monitoring of blood glucose--patient preference for 'BM-Test Glycemie 20-800' strips or 'Glucometer'.

Germer S, Campbell IW.

Br J Clin Pract. 1985 Jun;39(6):225-7. No abstract available.

PMID:
4041348
44.

Aetiology of pneumonia in children in Goroka Hospital, Papua New Guinea.

Shann F, Gratten M, Germer S, Linnemann V, Hazlett D, Payne R.

Lancet. 1984 Sep 8;2(8402):537-41.

PMID:
6147602
45.

Treatment of bacterial meningitis without intravenous fluids.

Shann F, Germer S.

Med J Aust. 1983 Apr 2;1(7):305. No abstract available.

PMID:
6835130
46.

The clinical value of assessing glycosylated haemoglobin (HbA1) in a District General Hospital Diabetic Clinic.

Campbell IW, Smith AW, Boyd SG, Duncan CD, Germer S, Sutherland JD, Golda BP, Jones IG.

Health Bull (Edinb). 1983 Mar;41(2):95-9. No abstract available.

PMID:
6341314
47.

Home-monitoring of blood glucose.

Germer S, Campbell IW.

Practitioner. 1982 Jun;226(1368):1135-7. No abstract available.

PMID:
7111146
48.

Treatment of bacterial meningitis in children without intravenous fluids.

Shann F, Germer S.

Med J Aust. 1981 May 30;1(11):577-8.

PMID:
7254034
49.

Rotavirus infection in young children in the highlands of Papua New Guinea.

Shann FA, Germer S, Lansdown S, Bugg HC, Bishop RF, Barnes GL.

Med J Aust. 1980 Aug 9;2(3):153-4.

PMID:
6252422
50.

Childhood pneumonia at Goroka Hospital.

Shann F, Germer S.

P N G Med J. 1979 Dec;22(4):72-5.

PMID:
299332

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