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Items: 49

1.

Dynamics of sister chromatid resolution during cell cycle progression.

Stanyte R, Nuebler J, Blaukopf C, Hoefler R, Stocsits R, Peters JM, Gerlich DW.

J Cell Biol. 2018 Jun 4;217(6):1985-2004. doi: 10.1083/jcb.201801157. Epub 2018 Apr 25.

PMID:
29695489
2.

PARP inhibition causes premature loss of cohesion in cancer cells.

Kukolj E, Kaufmann T, Dick AE, Zeillinger R, Gerlich DW, Slade D.

Oncotarget. 2017 Oct 16;8(61):103931-103951. doi: 10.18632/oncotarget.21879. eCollection 2017 Nov 28.

3.

Cytokinesis in vertebrate cells initiates by contraction of an equatorial actomyosin network composed of randomly oriented filaments.

Spira F, Cuylen-Haering S, Mehta S, Samwer M, Reversat A, Verma A, Oldenbourg R, Sixt M, Gerlich DW.

Elife. 2017 Nov 6;6. pii: e30867. doi: 10.7554/eLife.30867.

4.

A deep learning and novelty detection framework for rapid phenotyping in high-content screening.

Sommer C, Hoefler R, Samwer M, Gerlich DW.

Mol Biol Cell. 2017 Nov 7;28(23):3428-3436. doi: 10.1091/mbc.E17-05-0333. Epub 2017 Sep 27.

5.

Cell organization by liquid phase separation.

Gerlich DW.

Nat Rev Mol Cell Biol. 2017 Oct;18(10):593. doi: 10.1038/nrm.2017.93. Epub 2017 Sep 6. No abstract available.

PMID:
28875993
6.

DNA Cross-Bridging Shapes a Single Nucleus from a Set of Mitotic Chromosomes.

Samwer M, Schneider MWG, Hoefler R, Schmalhorst PS, Jude JG, Zuber J, Gerlich DW.

Cell. 2017 Aug 24;170(5):956-972.e23. doi: 10.1016/j.cell.2017.07.038.

7.

Dynamic subunit turnover in ESCRT-III assemblies is regulated by Vps4 to mediate membrane remodelling during cytokinesis.

Mierzwa BE, Chiaruttini N, Redondo-Morata L, von Filseck JM, König J, Larios J, Poser I, Müller-Reichert T, Scheuring S, Roux A, Gerlich DW.

Nat Cell Biol. 2017 Jul;19(7):787-798. doi: 10.1038/ncb3559. Epub 2017 Jun 12.

8.

Profiling DNA damage response following mitotic perturbations.

S Pedersen R, Karemore G, Gudjonsson T, Rask MB, Neumann B, Hériché JK, Pepperkok R, Ellenberg J, Gerlich DW, Lukas J, Lukas C.

Nat Commun. 2016 Dec 15;7:13887. doi: 10.1038/ncomms13887.

9.

MicroRNA-34/449 controls mitotic spindle orientation during mammalian cortex development.

Fededa JP, Esk C, Mierzwa B, Stanyte R, Yuan S, Zheng H, Ebnet K, Yan W, Knoblich JA, Gerlich DW.

EMBO J. 2016 Nov 15;35(22):2386-2398. Epub 2016 Oct 5.

10.

Ki-67 acts as a biological surfactant to disperse mitotic chromosomes.

Cuylen S, Blaukopf C, Politi AZ, Müller-Reichert T, Neumann B, Poser I, Ellenberg J, Hyman AA, Gerlich DW.

Nature. 2016 Jul 14;535(7611):308-12. doi: 10.1038/nature18610. Epub 2016 Jun 29.

11.

Augmin shapes the anaphase spindle for efficient cytokinetic furrow ingression and abscission.

Uehara R, Kamasaki T, Hiruma S, Poser I, Yoda K, Yajima J, Gerlich DW, Goshima G.

Mol Biol Cell. 2016 Mar 1;27(5):812-27. doi: 10.1091/mbc.E15-02-0101. Epub 2016 Jan 13.

12.

SiR-Hoechst is a far-red DNA stain for live-cell nanoscopy.

Lukinavičius G, Blaukopf C, Pershagen E, Schena A, Reymond L, Derivery E, Gonzalez-Gaitan M, D'Este E, Hell SW, Gerlich DW, Johnsson K.

Nat Commun. 2015 Oct 1;6:8497. doi: 10.1038/ncomms9497.

13.

Chromosome Missegregation Associated with RUVBL1 Deficiency.

Gentili C, Castor D, Kaden S, Lauterbach D, Gysi M, Steigemann P, Gerlich DW, Jiricny J, Ferrari S.

PLoS One. 2015 Jul 22;10(7):e0133576. doi: 10.1371/journal.pone.0133576. eCollection 2015.

14.

Efficacy and mechanism of action of volasertib, a potent and selective inhibitor of Polo-like kinases, in preclinical models of acute myeloid leukemia.

Rudolph D, Impagnatiello MA, Blaukopf C, Sommer C, Gerlich DW, Roth M, Tontsch-Grunt U, Wernitznig A, Savarese F, Hofmann MH, Albrecht C, Geiselmann L, Reschke M, Garin-Chesa P, Zuber J, Moll J, Adolf GR, Kraut N.

J Pharmacol Exp Ther. 2015 Mar;352(3):579-89. doi: 10.1124/jpet.114.221150. Epub 2015 Jan 9.

15.

Cytokinetic abscission: molecular mechanisms and temporal control.

Mierzwa B, Gerlich DW.

Dev Cell. 2014 Dec 8;31(5):525-38. doi: 10.1016/j.devcel.2014.11.006. Review.

16.

Fluorogenic probes for live-cell imaging of the cytoskeleton.

Lukinavičius G, Reymond L, D'Este E, Masharina A, Göttfert F, Ta H, Güther A, Fournier M, Rizzo S, Waldmann H, Blaukopf C, Sommer C, Gerlich DW, Arndt HD, Hell SW, Johnsson K.

Nat Methods. 2014 Jul;11(7):731-3. doi: 10.1038/nmeth.2972. Epub 2014 May 25.

PMID:
24859753
17.

SUN proteins facilitate the removal of membranes from chromatin during nuclear envelope breakdown.

Turgay Y, Champion L, Balazs C, Held M, Toso A, Gerlich DW, Meraldi P, Kutay U.

J Cell Biol. 2014 Mar 31;204(7):1099-109. doi: 10.1083/jcb.201310116. Epub 2014 Mar 24.

18.

Cdk1 inactivation terminates mitotic checkpoint surveillance and stabilizes kinetochore attachments in anaphase.

Vázquez-Novelle MD, Sansregret L, Dick AE, Smith CA, McAinsh AD, Gerlich DW, Petronczki M.

Curr Biol. 2014 Mar 17;24(6):638-45. doi: 10.1016/j.cub.2014.01.034. Epub 2014 Feb 27.

19.

Machine learning in cell biology - teaching computers to recognize phenotypes.

Sommer C, Gerlich DW.

J Cell Sci. 2013 Dec 15;126(Pt 24):5529-39. doi: 10.1242/jcs.123604. Epub 2013 Nov 20. Review.

20.

Kinetic framework of spindle assembly checkpoint signalling.

Dick AE, Gerlich DW.

Nat Cell Biol. 2013 Nov;15(11):1370-7. doi: 10.1038/ncb2842. Epub 2013 Oct 6.

21.

Aurora B and Kif2A control microtubule length for assembly of a functional central spindle during anaphase.

Uehara R, Tsukada Y, Kamasaki T, Poser I, Yoda K, Gerlich DW, Goshima G.

J Cell Biol. 2013 Aug 19;202(4):623-36. doi: 10.1083/jcb.201302123.

22.

The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis.

Samwer M, Dehne HJ, Spira F, Kollmar M, Gerlich DW, Urlaub H, Görlich D.

EMBO J. 2013 Jul 3;32(13):1886-902. doi: 10.1038/emboj.2013.108. Epub 2013 May 31.

23.

CellH5: a format for data exchange in high-content screening.

Sommer C, Held M, Fischer B, Huber W, Gerlich DW.

Bioinformatics. 2013 Jun 15;29(12):1580-2. doi: 10.1093/bioinformatics/btt175. Epub 2013 Apr 16.

24.

Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant.

Earnshaw WC, Allshire RC, Black BE, Bloom K, Brinkley BR, Brown W, Cheeseman IM, Choo KH, Copenhaver GP, Deluca JG, Desai A, Diekmann S, Erhardt S, Fitzgerald-Hayes M, Foltz D, Fukagawa T, Gassmann R, Gerlich DW, Glover DM, Gorbsky GJ, Harrison SC, Heun P, Hirota T, Jansen LE, Karpen G, Kops GJ, Lampson MA, Lens SM, Losada A, Luger K, Maiato H, Maddox PS, Margolis RL, Masumoto H, McAinsh AD, Mellone BG, Meraldi P, Musacchio A, Oegema K, O'Neill RJ, Salmon ED, Scott KC, Straight AF, Stukenberg PT, Sullivan BA, Sullivan KF, Sunkel CE, Swedlow JR, Walczak CE, Warburton PE, Westermann S, Willard HF, Wordeman L, Yanagida M, Yen TJ, Yoda K, Cleveland DW.

Chromosome Res. 2013 Apr;21(2):101-6. doi: 10.1007/s10577-013-9347-y. Epub 2013 Apr 12.

25.

Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores.

Wurzenberger C, Held M, Lampson MA, Poser I, Hyman AA, Gerlich DW.

J Cell Biol. 2012 Jul 23;198(2):173-83. doi: 10.1083/jcb.201112112. Epub 2012 Jul 16.

26.

Mps1 promotes rapid centromere accumulation of Aurora B.

van der Waal MS, Saurin AT, Vromans MJ, Vleugel M, Wurzenberger C, Gerlich DW, Medema RH, Kops GJ, Lens SM.

EMBO Rep. 2012 Sep;13(9):847-54. doi: 10.1038/embor.2012.93. Epub 2012 Jun 26.

27.

Unsupervised modeling of cell morphology dynamics for time-lapse microscopy.

Zhong Q, Busetto AG, Fededa JP, Buhmann JM, Gerlich DW.

Nat Methods. 2012 May 27;9(7):711-3. doi: 10.1038/nmeth.2046.

PMID:
22635062
28.

Molecular control of animal cell cytokinesis.

Fededa JP, Gerlich DW.

Nat Cell Biol. 2012 May 2;14(5):440-7. doi: 10.1038/ncb2482. Review.

PMID:
22552143
29.

ESCRT-III polymers in membrane neck constriction.

Guizetti J, Gerlich DW.

Trends Cell Biol. 2012 Mar;22(3):133-40. doi: 10.1016/j.tcb.2011.11.007. Epub 2012 Jan 10.

PMID:
22240455
30.

Phosphatases: providing safe passage through mitotic exit.

Wurzenberger C, Gerlich DW.

Nat Rev Mol Cell Biol. 2011 Jul 13;12(8):469-82. doi: 10.1038/nrm3149. Review.

PMID:
21750572
31.

Cdc48/p97-Ufd1-Npl4 antagonizes Aurora B during chromosome segregation in HeLa cells.

Dobrynin G, Popp O, Romer T, Bremer S, Schmitz MH, Gerlich DW, Meyer H.

J Cell Sci. 2011 May 1;124(Pt 9):1571-80. doi: 10.1242/jcs.069500. Epub 2011 Apr 12.

32.

Cortical constriction during abscission involves helices of ESCRT-III-dependent filaments.

Guizetti J, Schermelleh L, Mäntler J, Maar S, Poser I, Leonhardt H, Müller-Reichert T, Gerlich DW.

Science. 2011 Mar 25;331(6024):1616-20. doi: 10.1126/science.1201847. Epub 2011 Feb 10.

33.

RNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells.

Piwko W, Olma MH, Held M, Bianco JN, Pedrioli PG, Hofmann K, Pasero P, Gerlich DW, Peter M.

EMBO J. 2010 Dec 15;29(24):4210-22. doi: 10.1038/emboj.2010.304. Epub 2010 Nov 26.

34.

Correlative time-lapse imaging and electron microscopy to study abscission in HeLa cells.

Guizetti J, Mäntler J, Müller-Reichert T, Gerlich DW.

Methods Cell Biol. 2010;96:591-601. doi: 10.1016/S0091-679X(10)96024-X.

PMID:
20869539
35.

Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells.

Schmitz MH, Held M, Janssens V, Hutchins JR, Hudecz O, Ivanova E, Goris J, Trinkle-Mulcahy L, Lamond AI, Poser I, Hyman AA, Mechtler K, Peters JM, Gerlich DW.

Nat Cell Biol. 2010 Sep;12(9):886-93. doi: 10.1038/ncb2092. Epub 2010 Aug 15.

36.

Cytokinetic abscission in animal cells.

Guizetti J, Gerlich DW.

Semin Cell Dev Biol. 2010 Dec;21(9):909-16. doi: 10.1016/j.semcdb.2010.08.001. Epub 2010 Aug 11. Review.

PMID:
20708087
37.

CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging.

Held M, Schmitz MH, Fischer B, Walter T, Neumann B, Olma MH, Peter M, Ellenberg J, Gerlich DW.

Nat Methods. 2010 Sep;7(9):747-54. doi: 10.1038/nmeth.1486. Epub 2010 Aug 8.

PMID:
20693996
38.

Tubulin polyglutamylation stimulates spastin-mediated microtubule severing.

Lacroix B, van Dijk J, Gold ND, Guizetti J, Aldrian-Herrada G, Rogowski K, Gerlich DW, Janke C.

J Cell Biol. 2010 Jun 14;189(6):945-54. doi: 10.1083/jcb.201001024. Epub 2010 Jun 7.

39.

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes.

Neumann B, Walter T, Hériché JK, Bulkescher J, Erfle H, Conrad C, Rogers P, Poser I, Held M, Liebel U, Cetin C, Sieckmann F, Pau G, Kabbe R, Wünsche A, Satagopam V, Schmitz MH, Chapuis C, Gerlich DW, Schneider R, Eils R, Huber W, Peters JM, Hyman AA, Durbin R, Pepperkok R, Ellenberg J.

Nature. 2010 Apr 1;464(7289):721-7. doi: 10.1038/nature08869.

40.

Evidence that the tumor-suppressor protein BRCA2 does not regulate cytokinesis in human cells.

Lekomtsev S, Guizetti J, Pozniakovsky A, Gerlich DW, Petronczki M.

J Cell Sci. 2010 May 1;123(Pt 9):1395-400. doi: 10.1242/jcs.068015. Epub 2010 Mar 31.

41.

Automated microscopy for high-content RNAi screening.

Conrad C, Gerlich DW.

J Cell Biol. 2010 Feb 22;188(4):453-61. doi: 10.1083/jcb.200910105. Review.

42.

The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis.

Maerki S, Olma MH, Staubli T, Steigemann P, Gerlich DW, Quadroni M, Sumara I, Peter M.

J Cell Biol. 2009 Dec 14;187(6):791-800. doi: 10.1083/jcb.200906117.

43.

Mitotic phosphatases: from entry guards to exit guides.

Bollen M, Gerlich DW, Lesage B.

Trends Cell Biol. 2009 Oct;19(10):531-41. doi: 10.1016/j.tcb.2009.06.005. Epub 2009 Sep 4. Review.

PMID:
19734049
44.

Cytokinetic abscission: cellular dynamics at the midbody.

Steigemann P, Gerlich DW.

Trends Cell Biol. 2009 Nov;19(11):606-16. doi: 10.1016/j.tcb.2009.07.008. Epub 2009 Sep 3. Review.

PMID:
19733077
45.

Automated live microscopy to study mitotic gene function in fluorescent reporter cell lines.

Schmitz MH, Gerlich DW.

Methods Mol Biol. 2009;545:113-34. doi: 10.1007/978-1-60327-993-2_7.

PMID:
19475385
46.

An evolutionary conserved checkpoint controls abscission timing.

Steigemann P, Gerlich DW.

Cell Cycle. 2009 Jun 15;8(12):1814-5. Epub 2009 Jun 6. No abstract available.

PMID:
19471121
47.

Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly.

Chan YW, Fava LL, Uldschmid A, Schmitz MH, Gerlich DW, Nigg EA, Santamaria A.

J Cell Biol. 2009 Jun 1;185(5):859-74. doi: 10.1083/jcb.200812167. Epub 2009 May 25.

48.

Assays for mitotic chromosome condensation in live yeast and mammalian cells.

Neurohr G, Gerlich DW.

Chromosome Res. 2009;17(2):145-54. doi: 10.1007/s10577-008-9010-1. Review.

PMID:
19308697
49.

Aurora B-mediated abscission checkpoint protects against tetraploidization.

Steigemann P, Wurzenberger C, Schmitz MH, Held M, Guizetti J, Maar S, Gerlich DW.

Cell. 2009 Feb 6;136(3):473-84. doi: 10.1016/j.cell.2008.12.020.

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