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Items: 1 to 50 of 239

1.

Rapid immunity to vaccination with woodchuck hepatitis virus surface antigen using cationic liposome-DNA complexes as adjuvant.

Cote PJ, Butler SD, George AL, Fairman J, Gerin JL, Tennant BC, Menne S.

J Med Virol. 2009 Oct;81(10):1760-72. doi: 10.1002/jmv.21566.

PMID:
19697409
2.

Antiviral effects of lamivudine, emtricitabine, adefovir dipivoxil, and tenofovir disoproxil fumarate administered orally alone and in combination to woodchucks with chronic woodchuck hepatitis virus infection.

Menne S, Butler SD, George AL, Tochkov IA, Zhu Y, Xiong S, Gerin JL, Cote PJ, Tennant BC.

Antimicrob Agents Chemother. 2008 Oct;52(10):3617-32. doi: 10.1128/AAC.00654-08. Epub 2008 Aug 1.

3.

Treatment of chronic delta hepatitis with lamivudine vs lamivudine + interferon vs interferon.

Yurdaydin C, Bozkaya H, Onder FO, Sentürk H, Karaaslan H, Akdoğan M, Cetinkaya H, Erden E, Erkan-Esin O, Yalçin K, Bozdayi AM, Schinazi RF, Gerin JL, Uzunalimoğlu O, Ozden A.

J Viral Hepat. 2008 Apr;15(4):314-21. doi: 10.1111/j.1365-2893.2007.00936.x.

PMID:
18307594
5.

Antiviral effect of orally administered (-)-beta-D-2-aminopurine dioxolane in woodchucks with chronic woodchuck hepatitis virus infection.

Menne S, Asif G, Narayanasamy J, Butler SD, George AL, Hurwitz SJ, Schinazi RF, Chu CK, Cote PJ, Gerin JL, Tennant BC.

Antimicrob Agents Chemother. 2007 Sep;51(9):3177-84. Epub 2007 Jul 2.

6.

Immunosuppression reactivates viral replication long after resolution of woodchuck hepatitis virus infection.

Menne S, Cote PJ, Butler SD, Toshkov IA, Gerin JL, Tennant BC.

Hepatology. 2007 Mar;45(3):614-22.

PMID:
17326155
7.

The woodchuck model of HDV infection.

Casey JL, Gerin JL.

Curr Top Microbiol Immunol. 2006;307:211-25. Review.

PMID:
16903228
8.

Native hepatitis B virions and capsids visualized by electron cryomicroscopy.

Dryden KA, Wieland SF, Whitten-Bauer C, Gerin JL, Chisari FV, Yeager M.

Mol Cell. 2006 Jun 23;22(6):843-50.

9.
10.

Clevudine inhibits hepatitis delta virus viremia: a pilot study of chronically infected woodchucks.

Casey J, Cote PJ, Toshkov IA, Chu CK, Gerin JL, Hornbuckle WE, Tennant BC, Korba BE.

Antimicrob Agents Chemother. 2005 Oct;49(10):4396-9.

11.

Antiviral effect of oral administration of tenofovir disoproxil fumarate in woodchucks with chronic woodchuck hepatitis virus infection.

Menne S, Cote PJ, Korba BE, Butler SD, George AL, Tochkov IA, Delaney WE 4th, Xiong S, Gerin JL, Tennant BC.

Antimicrob Agents Chemother. 2005 Jul;49(7):2720-8.

12.

Clevudine therapy with vaccine inhibits progression of chronic hepatitis and delays onset of hepatocellular carcinoma in chronic woodchuck hepatitis virus infection.

Korba BE, Cote PJ, Menne S, Toshkov I, Baldwin BH, Wells FV, Tennant BC, Gerin JL.

Antivir Ther. 2004 Dec;9(6):937-52.

PMID:
15651753
13.

Hepatocellular carcinoma in the woodchuck model of hepatitis B virus infection.

Tennant BC, Toshkov IA, Peek SF, Jacob JR, Menne S, Hornbuckle WE, Schinazi RD, Korba BE, Cote PJ, Gerin JL.

Gastroenterology. 2004 Nov;127(5 Suppl 1):S283-93. Review.

PMID:
15508096
14.

Interferon-gamma-associated responses to woodchuck hepatitis virus infection in neonatal woodchucks and virus-infected hepatocytes.

Wang Y, Jacob JR, Menne S, Bellezza CA, Tennant BC, Gerin JL, Cote PJ.

J Viral Hepat. 2004 Sep;11(5):404-17.

PMID:
15357645
15.
16.

Suppression of lamivudine-resistant B-domain mutants by adefovir dipivoxil in the woodchuck hepatitis virus model.

Jacob JR, Korba BE, Cote PJ, Toshkov I, Delaney WE 4th, Gerin JL, Tennant BC.

Antiviral Res. 2004 Aug;63(2):115-21.

PMID:
15302140
17.

Integration of woodchuck hepatitis and N-myc rearrangement determine size and histologic grade of hepatic tumors.

Jacob JR, Sterczer A, Toshkov IA, Yeager AE, Korba BE, Cote PJ, Buendia MA, Gerin JL, Tennant BC.

Hepatology. 2004 Apr;39(4):1008-16.

PMID:
15057905
18.

Kinetics of viremia and acute liver injury in relation to outcome of neonatal woodchuck hepatitis virus infection.

Wang Y, Menne S, Baldwin BH, Tennant BC, Gerin JL, Cote PJ.

J Med Virol. 2004 Mar;72(3):406-15.

PMID:
14748064
19.

Global screening for human viral pathogens.

Anderson NG, Gerin JL, Anderson NL.

Emerg Infect Dis. 2003 Jul;9(7):768-74.

20.

Role of type 1 versus type 2 immune responses in liver during the onset of chronic woodchuck hepatitis virus infection.

Wang Y, Menne S, Jacob JR, Tennant BC, Gerin JL, Cote PJ.

Hepatology. 2003 Apr;37(4):771-80.

PMID:
12668969
22.

Viral pharmacodynamic model for (-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine (emtricitabine) in chronically infected woodchucks.

Hurwitz SJ, Tennant BC, Korba BE, Liberman I, Gerin JL, Schinazi RF.

Antivir Chem Chemother. 2002 May;13(3):165-76.

PMID:
12448689
23.

Mutations in the conserved woodchuck hepatitis virus polymerase FLLA and YMDD regions conferring resistance to lamivudine.

Tatti KM, Korba BE, Stang HL, Peek S, Gerin JL, Tennant BC, Schinazi RF.

Antiviral Res. 2002 Jul;55(1):141-50.

PMID:
12076758
24.

Real-time polymerase chain reaction assays for leukocyte CD and cytokine mRNAs of the Eastern woodchuck (Marmota monax).

Menne S, Wang Y, Butler SD, Gerin JL, Cote PJ, Tennant BC.

Vet Immunol Immunopathol. 2002 Aug;87(1-2):97-105.

PMID:
12052347
27.

Immunogenicity and protective efficacy of a vaccine prepared from 53 kDa truncated hepatitis E virus capsid protein expressed in insect cells.

Zhang M, Emerson SU, Nguyen H, Engle RE, Govindarajan S, Gerin JL, Purcell RH.

Vaccine. 2001 Dec 12;20(5-6):853-7.

PMID:
11738749
28.

Animal models of hepatitis delta virus infection and disease.

Gerin JL.

ILAR J. 2001;42(2):103-6. Review.

PMID:
11406712
29.

The woodchuck model of hepatitis B virus infection.

Tennant BC, Gerin JL.

ILAR J. 2001;42(2):89-102. Review.

PMID:
11406711
30.

An outbreak of fulminant hepatitis delta in the Waorani, an indigenous people of the Amazon basin of Ecuador.

Manock SR, Kelley PM, Hyams KC, Douce R, Smalligan RD, Watts DM, Sharp TW, Casey JL, Gerin JL, Engle R, Alava-Alprecht A, Martínez CM, Bravo NB, Guevara AG, Russell KL, Mendoza W, Vimos C.

Am J Trop Med Hyg. 2000 Sep-Oct;63(3-4):209-13.

PMID:
11388517
32.

Antiviral activity of clevudine [L-FMAU, (1-(2-fluoro-5-methyl-beta, L-arabinofuranosyl) uracil)] against woodchuck hepatitis virus replication and gene expression in chronically infected woodchucks (Marmota monax).

Peek SF, Cote PJ, Jacob JR, Toshkov IA, Hornbuckle WE, Baldwin BH, Wells FV, Chu CK, Gerin JL, Tennant BC, Korba BE.

Hepatology. 2001 Jan;33(1):254-66.

PMID:
11124844
33.

Temporal pathogenesis of experimental neonatal woodchuck hepatitis virus infection: increased initial viral load and decreased severity of acute hepatitis during the development of chronic viral infection.

Cote PJ, Toshkov I, Bellezza C, Ascenzi M, Roneker C, Ann Graham L, Baldwin BH, Gaye K, Nakamura I, Korba BE, Tennant BC, Gerin JL.

Hepatology. 2000 Oct;32(4 Pt 1):807-17.

PMID:
11003627
34.

Enhanced antiviral benefit of combination therapy with lamivudine and alpha interferon against WHV replication in chronic carrier woodchucks.

Korba BE, Cote P, Hornbuckle W, Schinazi R, Gangemi JD, Tennant BC, Gerin JL.

Antivir Ther. 2000 Jun;5(2):95-104.

PMID:
10971862
35.

Antiviral activities of oral 1-O-hexadecylpropanediol-3-phosphoacyclovir and acyclovir in woodchucks with chronic woodchuck hepatitis virus infection.

Hostetler KY, Beadle JR, Hornbuckle WE, Bellezza CA, Tochkov IA, Cote PJ, Gerin JL, Korba BE, Tennant BC.

Antimicrob Agents Chemother. 2000 Jul;44(7):1964-9.

36.

Effect of oral administration of emtricitabine on woodchuck hepatitis virus replication in chronically infected woodchucks.

Korba BE, Schinazi RF, Cote P, Tennant BC, Gerin JL.

Antimicrob Agents Chemother. 2000 Jun;44(6):1757-60.

38.

Enhanced antiviral benefit of combination therapy with lamivudine and famciclovir against WHV replication in chronic WHV carrier woodchucks.

Korba BE, Cote P, Hornbuckle W, Schinazi R, Gerin JL, Tennant BC.

Antiviral Res. 2000 Jan;45(1):19-32. Erratum in: Antiviral Res 2000 Feb;45(2):155-6.

PMID:
10774587
39.

Preclinical investigation of L-FMAU as an anti-hepatitis B virus agent.

Chu CK, Boudinot FD, Peek SF, Hong JH, Choi Y, Korba BE, Gerin JL, Cote PJ, Tennant BC, Cheng YC.

Antivir Ther. 1998;3(Suppl 3):113-21. Review.

PMID:
10726061
40.

Effects of age and viral determinants on chronicity as an outcome of experimental woodchuck hepatitis virus infection.

Cote PJ, Korba BE, Miller RH, Jacob JR, Baldwin BH, Hornbuckle WE, Purcell RH, Tennant BC, Gerin JL.

Hepatology. 2000 Jan;31(1):190-200.

PMID:
10613745
41.

Pharmacodynamics of (-)-beta-2',3'-dideoxy-3'-thiacytidine in chronically virus-infected woodchucks compared to its pharmacodynamics in humans.

Hurwitz SJ, Tennant BC, Korba BE, Gerin JL, Schinazi RF.

Antimicrob Agents Chemother. 1998 Nov;42(11):2804-9. Erratum in: Antimicrob Agents Chemother 1998 Dec;42(12):3337.

42.

Antiviral activity and toxicity of fialuridine in the woodchuck model of hepatitis B virus infection.

Tennant BC, Baldwin BH, Graham LA, Ascenzi MA, Hornbuckle WE, Rowland PH, Tochkov IA, Yeager AE, Erb HN, Colacino JM, Lopez C, Engelhardt JA, Bowsher RR, Richardson FC, Lewis W, Cote PJ, Korba BE, Gerin JL.

Hepatology. 1998 Jul;28(1):179-91.

PMID:
9657111
43.

Hepatitis D viremia following orthotopic liver transplantation involves a typical HDV virion with a hepatitis B surface antigen envelope.

Smedile A, Casey JL, Cote PJ, Durazzo M, Lavezzo B, Purcell RH, Rizzetto M, Gerin JL.

Hepatology. 1998 Jun;27(6):1723-9.

PMID:
9620349
45.

Titration of recombinant woodchuck hepatitis virus DNA in adult woodchucks.

Chen HS, Miller RH, Hornbuckle WE, Tennant BC, Cote PJ, Gerin JL, Purcell RH.

J Med Virol. 1998 Feb;54(2):92-4.

PMID:
9496365
46.

Recombinant vaccine against hepatitis E: dose response and protection against heterologous challenge.

Tsarev SA, Tsareva TS, Emerson SU, Govindarajan S, Shapiro M, Gerin JL, Purcell RH.

Vaccine. 1997 Dec;15(17-18):1834-8.

PMID:
9413090
47.

Hepatic expression of the woodchuck hepatitis virus X-antigen during acute and chronic infection and detection of a woodchuck hepatitis virus X-antigen antibody response.

Jacob JR, Ascenzi MA, Roneker CA, Toshkov IA, Cote PJ, Gerin JL, Tennant BC.

Hepatology. 1997 Dec;26(6):1607-15.

PMID:
9398005
48.

Cloning and characterization of partial cDNAs for woodchuck cytokines and CD3epsilon with applications for the detection of RNA expression in tissues by RT-PCR assay.

Nakamura I, Nupp JT, Rao BS, Buckler-White A, Engle RE, Casey JL, Gerin JL, Cote PJ.

J Med Virol. 1997 Sep;53(1):85-95.

PMID:
9298738
49.

Geographic distribution and genetic variability of hepatitis delta virus genotype I.

Shakil AO, Hadziyannis S, Hoofnagle JH, Di Bisceglie AM, Gerin JL, Casey JL.

Virology. 1997 Jul 21;234(1):160-7.

50.

The predominance of hepatitis delta virus genotype I among chronically infected Italian patients.

Niro GA, Smedile A, Andriulli A, Rizzetto M, Gerin JL, Casey JL.

Hepatology. 1997 Mar;25(3):728-34.

PMID:
9049226

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