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Items: 1 to 50 of 131

1.

Helicobacter pylori Exploits the NLRC4 Inflammasome to Dampen Host Defenses.

Semper RP, Vieth M, Gerhard M, Mejías-Luque R.

J Immunol. 2019 Oct 15;203(8):2183-2193. doi: 10.4049/jimmunol.1900351. Epub 2019 Sep 11.

PMID:
31511355
2.

Phytoplankton community responses to temperature fluctuations under different nutrient concentrations and stoichiometry.

Gerhard M, Koussoroplis AM, Hillebrand H, Striebel M.

Ecology. 2019 Jul 22:e02834. doi: 10.1002/ecy.2834. [Epub ahead of print]

PMID:
31330048
3.

Concomitant Infection of S. mansoni and H. pylori Promotes Promiscuity of Antigen-Experienced Cells and Primes the Liver for a Lower Fibrotic Response.

Bhattacharjee S, Mejías-Luque R, Loffredo-Verde E, Toska A, Flossdorf M, Gerhard M, Prazeres da Costa C.

Cell Rep. 2019 Jul 2;28(1):231-244.e5. doi: 10.1016/j.celrep.2019.05.108.

4.

Increased LIGHT expression and activation of non-canonical NF-κB are observed in gastric lesions of MyD88-deficient mice upon Helicobacter felis infection.

Mejías-Luque R, Lozano-Pope I, Wanisch A, Heikenwälder M, Gerhard M, Obonyo M.

Sci Rep. 2019 May 7;9(1):7030. doi: 10.1038/s41598-019-43417-x.

5.

Microscopic insight into non-radiative decay in perovskite semiconductors from temperature-dependent luminescence blinking.

Gerhard M, Louis B, Camacho R, Merdasa A, Li J, Kiligaridis A, Dobrovolsky A, Hofkens J, Scheblykin IG.

Nat Commun. 2019 Apr 12;10(1):1698. doi: 10.1038/s41467-019-09640-w.

6.

The Helicobacter pylori HopQ outermembrane protein inhibits immune cell activities.

Gur C, Maalouf N, Gerhard M, Singer BB, Emgård J, Temper V, Neuman T, Mandelboim O, Bachrach G.

Oncoimmunology. 2019 Jan 29;8(4):e1553487. doi: 10.1080/2162402X.2018.1553487. eCollection 2019.

PMID:
30906650
7.

Mutated Rnf43 Aggravates Helicobacter Pylori-Induced Gastric Pathology.

Neumeyer V, Vieth M, Gerhard M, Mejías-Luque R.

Cancers (Basel). 2019 Mar 16;11(3). pii: E372. doi: 10.3390/cancers11030372.

8.

Loss of endogenous RNF43 function enhances proliferation and tumour growth of intestinal and gastric cells.

Neumeyer V, Grandl M, Dietl A, Brutau-Abia A, Allgäuer M, Kalali B, Zhang Y, Pan KF, Steiger K, Vieth M, Anton M, Mejías-Luque R, Gerhard M.

Carcinogenesis. 2019 Jun 10;40(4):551-559. doi: 10.1093/carcin/bgy152.

PMID:
30380024
9.

High Resolution Mapping of Two-Photon Excited Photocurrent in Perovskite Microplate Photodetector.

Yang B, Chen J, Shi Q, Wang Z, Gerhard M, Dobrovolsky A, Scheblykin IG, Karki KJ, Han K, Pullerits T.

J Phys Chem Lett. 2018 Sep 6;9(17):5017-5022. doi: 10.1021/acs.jpclett.8b02250. Epub 2018 Aug 22.

PMID:
30124049
10.

Association Between Gut Microbiota and Helicobacter pylori-Related Gastric Lesions in a High-Risk Population of Gastric Cancer.

Gao JJ, Zhang Y, Gerhard M, Mejias-Luque R, Zhang L, Vieth M, Ma JL, Bajbouj M, Suchanek S, Liu WD, Ulm K, Quante M, Li ZX, Zhou T, Schmid R, Classen M, Li WQ, You WC, Pan KF.

Front Cell Infect Microbiol. 2018 Jun 19;8:202. doi: 10.3389/fcimb.2018.00202. eCollection 2018.

11.

Pulmonary Hypertension in Aortic and Mitral Valve Disease.

Maeder MT, Weber L, Buser M, Gerhard M, Haager PK, Maisano F, Rickli H.

Front Cardiovasc Med. 2018 May 23;5:40. doi: 10.3389/fcvm.2018.00040. eCollection 2018.

12.

Helicobacter pylori adhesin HopQ disrupts trans dimerization in human CEACAMs.

Moonens K, Hamway Y, Neddermann M, Reschke M, Tegtmeyer N, Kruse T, Kammerer R, Mejías-Luque R, Singer BB, Backert S, Gerhard M, Remaut H.

EMBO J. 2018 Jul 2;37(13). pii: e98665. doi: 10.15252/embj.201798665. Epub 2018 Jun 1.

13.

Development of a Bead-Based Multiplex Assay for the Analysis of the Serological Response against the Six Pathogens HAV, HBV, HCV, CMV, T. gondii, and H. pylori.

Filomena A, Pessler F, Akmatov MK, Krause G, Duffy D, Gärtner B, Gerhard M, Albert ML, Joos TO, Schneiderhan-Marra N.

High Throughput. 2017 Oct 30;6(4). pii: E14. doi: 10.3390/ht6040014.

14.

BaiCD gene cluster abundance is negatively correlated with Clostridium difficile infection.

Solbach P, Chhatwal P, Woltemate S, Tacconelli E, Buhl M, Gerhard M, Thoeringer CK, Vehreschild MJGT, Jazmati N, Rupp J, Manns MP, Bachmann O, Suerbaum S.

PLoS One. 2018 May 8;13(5):e0196977. doi: 10.1371/journal.pone.0196977. eCollection 2018.

15.

Evidence suggests that germline RNF43 mutations are a rare cause of serrated polyposis.

Quintana I, Mejías-Luque R, Terradas M, Navarro M, Piñol V, Mur P, Belhadj S, Grau E, Darder E, Solanes A, Brunet J, Capellá G, Gerhard M, Valle L.

Gut. 2018 Dec;67(12):2230-2232. doi: 10.1136/gutjnl-2017-315733. Epub 2018 Jan 12. No abstract available.

PMID:
29330307
16.

Helicobacter pylori γ-glutamyl transferase contributes to colonization and differential recruitment of T cells during persistence.

Wüstner S, Anderl F, Wanisch A, Sachs C, Steiger K, Nerlich A, Vieth M, Mejías-Luque R, Gerhard M.

Sci Rep. 2017 Oct 20;7(1):13636. doi: 10.1038/s41598-017-14028-1.

17.

Performance of a Multiplex Serological Helicobacter pylori Assay on a Novel Microfluidic Assay Platform.

Filomena A, Guenther A, Planatscher H, Topin F, She J, Formichella L, Terradot L, Gerhard M, Joos TO, Meyer H, Schneiderhan-Marra N.

Proteomes. 2017 Oct 3;5(4). pii: E24. doi: 10.3390/proteomes5040024.

18.

Validation of a Novel Immunoline Assay for Patient Stratification according to Virulence of the Infecting Helicobacter pylori Strain and Eradication Status.

Formichella L, Romberg L, Meyer H, Bolz C, Vieth M, Geppert M, Göttner G, Nölting C, Schepp W, Schneider A, Ulm K, Wolf P, Holster IL, Kuipers EJ, Birkner B, Soutschek E, Gerhard M.

J Immunol Res. 2017;2017:8394593. doi: 10.1155/2017/8394593. Epub 2017 May 30.

19.

Evidence for Anisotropic Electronic Coupling of Charge Transfer States in Weakly Interacting Organic Semiconductor Mixtures.

Belova V, Beyer P, Meister E, Linderl T, Halbich MU, Gerhard M, Schmidt S, Zechel T, Meisel T, Generalov AV, Anselmo AS, Scholz R, Konovalov O, Gerlach A, Koch M, Hinderhofer A, Opitz A, Brütting W, Schreiber F.

J Am Chem Soc. 2017 Jun 28;139(25):8474-8486. doi: 10.1021/jacs.7b01622. Epub 2017 Jun 15.

PMID:
28570061
20.

Cut-off optimization for 13C-urea breath test in a community-based trial by mathematic, histology and serology approach.

Li ZX, Huang LL, Liu C, Formichella L, Zhang Y, Wang YM, Zhang L, Ma JL, Liu WD, Ulm K, Wang JX, Zhang L, Bajbouj M, Li M, Vieth M, Quante M, Zhou T, Wang LH, Suchanek S, Soutschek E, Schmid R, Classen M, You WC, Gerhard M, Pan KF.

Sci Rep. 2017 May 18;7(1):2072. doi: 10.1038/s41598-017-02180-7.

21.

Immune Evasion Strategies and Persistence of Helicobacter pylori.

Mejías-Luque R, Gerhard M.

Curr Top Microbiol Immunol. 2017;400:53-71. doi: 10.1007/978-3-319-50520-6_3. Review.

PMID:
28124149
22.

The Helicobacter pylori Type IV Secretion System Encoded by the cag Pathogenicity Island: Architecture, Function, and Signaling.

Backert S, Haas R, Gerhard M, Naumann M.

Curr Top Microbiol Immunol. 2017;413:187-220. doi: 10.1007/978-3-319-75241-9_8. Review.

PMID:
29536360
23.

Erratum: Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs.

Javaheri A, Kruse T, Moonens K, Mejías-Luque R, Debraekeleer A, Asche CI, Tegtmeyer N, Kalali B, Bach NC, Sieber SA, Hill DJ, Königer V, Hauck CR, Moskalenko R, Haas R, Busch DH, Klaile E, Slevogt H, Schmidt A, Backert S, Remaut H, Singer BB, Gerhard M.

Nat Microbiol. 2016 Nov 7;2:16243. doi: 10.1038/nmicrobiol.2016.243. No abstract available.

PMID:
27819267
24.

Mitochondrial function controls intestinal epithelial stemness and proliferation.

Berger E, Rath E, Yuan D, Waldschmitt N, Khaloian S, Allgäuer M, Staszewski O, Lobner EM, Schöttl T, Giesbertz P, Coleman OI, Prinz M, Weber A, Gerhard M, Klingenspor M, Janssen KP, Heikenwalder M, Haller D.

Nat Commun. 2016 Oct 27;7:13171. doi: 10.1038/ncomms13171.

25.

Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs.

Javaheri A, Kruse T, Moonens K, Mejías-Luque R, Debraekeleer A, Asche CI, Tegtmeyer N, Kalali B, Bach NC, Sieber SA, Hill DJ, Königer V, Hauck CR, Moskalenko R, Haas R, Busch DH, Klaile E, Slevogt H, Schmidt A, Backert S, Remaut H, Singer BB, Gerhard M.

Nat Microbiol. 2016 Oct 17;2:16189. doi: 10.1038/nmicrobiol.2016.189. Erratum in: Nat Microbiol. 2016 Nov 07;2:16243.

PMID:
27748768
26.

Comparison of enzymatic properties and small molecule inhibition of γ-glutamyltranspeptidases from pathogenic and commensal bacteria.

Bolz C, Bach NC, Meyer H, Müller G, Dawidowski M, Popowicz G, Sieber SA, Skerra A, Gerhard M.

Biol Chem. 2017 Mar;398(3):341-357. doi: 10.1515/hsz-2016-0198.

PMID:
27636829
27.

Inflammation, immunity, and vaccines for Helicobacter pylori infection.

Velin D, Straubinger K, Gerhard M.

Helicobacter. 2016 Sep;21 Suppl 1:26-9. doi: 10.1111/hel.12336. Review.

PMID:
27531535
28.

Lymphotoxin β receptor signalling executes Helicobacter pylori-driven gastric inflammation in a T4SS-dependent manner.

Mejías-Luque R, Zöller J, Anderl F, Loew-Gil E, Vieth M, Adler T, Engler DB, Urban S, Browning JL, Müller A, Gerhard M, Heikenwalder M.

Gut. 2017 Aug;66(8):1369-1381. doi: 10.1136/gutjnl-2015-310783. Epub 2016 Apr 13.

PMID:
27196595
29.

Helicobacter pylori γ-Glutamyltranspeptidase Induces Tolerogenic Human Dendritic Cells by Activation of Glutamate Receptors.

Käbisch R, Semper RP, Wüstner S, Gerhard M, Mejías-Luque R.

J Immunol. 2016 May 15;196(10):4246-52. doi: 10.4049/jimmunol.1501062. Epub 2016 Apr 18.

30.

Helicobacter pylori HP0231 Influences Bacterial Virulence and Is Essential for Gastric Colonization.

Zhong Y, Anderl F, Kruse T, Schindele F, Jagusztyn-Krynicka EK, Fischer W, Gerhard M, Mejías-Luque R.

PLoS One. 2016 May 3;11(5):e0154643. doi: 10.1371/journal.pone.0154643. eCollection 2016.

31.

T cell-specific inactivation of mouse CD2 by CRISPR/Cas9.

Beil-Wagner J, Dössinger G, Schober K, vom Berg J, Tresch A, Grandl M, Palle P, Mair F, Gerhard M, Becher B, Busch DH, Buch T.

Sci Rep. 2016 Feb 23;6:21377. doi: 10.1038/srep21377.

32.

High Frequency of vacA s1m2 Genotypes Among Helicobacter pylori Isolates From Patients With Gastroduodenal Disorders in Kermanshah, Iran.

Pajavand H, Alvandi A, Mohajeri P, Bakhtyari S, Bashiri H, Kalali B, Gerhard M, Najafi F, Abiri R.

Jundishapur J Microbiol. 2015 Nov 22;8(11):e25425. doi: 10.5812/jjm.25425. eCollection 2015 Nov.

33.

Characterisation of worldwide Helicobacter pylori strains reveals genetic conservation and essentiality of serine protease HtrA.

Tegtmeyer N, Moodley Y, Yamaoka Y, Pernitzsch SR, Schmidt V, Traverso FR, Schmidt TP, Rad R, Yeoh KG, Bow H, Torres J, Gerhard M, Schneider G, Wessler S, Backert S.

Mol Microbiol. 2016 Mar;99(5):925-44. doi: 10.1111/mmi.13276. Epub 2015 Dec 22.

34.

IL-1α is a DNA damage sensor linking genotoxic stress signaling to sterile inflammation and innate immunity.

Cohen I, Rider P, Vornov E, Tomas M, Tudor C, Wegner M, Brondani L, Freudenberg M, Mittler G, Ferrando-May E, Dinarello CA, Apte RN, Schneider R.

Sci Rep. 2015 Oct 6;5:14756. doi: 10.1038/srep14756. Erratum in: Sci Rep. 2016;6:19100. Multiple author names corrected.

35.

The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane.

Loregger A, Grandl M, Mejías-Luque R, Allgäuer M, Degenhart K, Haselmann V, Oikonomou C, Hatzis P, Janssen KP, Nitsche U, Gradl D, van den Broek O, Destree O, Ulm K, Neumaier M, Kalali B, Jung A, Varela I, Schmid RM, Rad R, Busch DH, Gerhard M.

Sci Signal. 2015 Sep 8;8(393):ra90. doi: 10.1126/scisignal.aac6757.

PMID:
26350900
36.

Diagnosis of Helicobacter pylori: Changes towards the Future.

Kalali B, Formichella L, Gerhard M.

Diseases. 2015 Jun 29;3(3):122-135. doi: 10.3390/diseases3030122. Review.

37.

A large randomised controlled intervention trial to prevent gastric cancer by eradication of Helicobacter pylori in Linqu County, China: baseline results and factors affecting the eradication.

Pan KF, Zhang L, Gerhard M, Ma JL, Liu WD, Ulm K, Wang JX, Zhang L, Zhang Y, Bajbouj M, Zhang LF, Li M, Vieth M, Liu RY, Quante M, Wang LH, Suchanek S, Zhou T, Guan WX, Schmid R, Classen M, You WC.

Gut. 2016 Jan;65(1):9-18. doi: 10.1136/gutjnl-2015-309197. Epub 2015 May 18.

PMID:
25986943
38.

Helicobacter pylori vaccination: is there a path to protection?

Anderl F, Gerhard M.

World J Gastroenterol. 2014 Sep 14;20(34):11939-49. doi: 10.3748/wjg.v20.i34.11939. Review.

39.

The highly conserved proline at position 438 in pseudorabies virus gH is important for regulation of membrane fusion.

Schröter C, Klupp BG, Fuchs W, Gerhard M, Backovic M, Rey FA, Mettenleiter TC.

J Virol. 2014 Nov;88(22):13064-72. doi: 10.1128/JVI.01204-14. Epub 2014 Sep 3.

40.

Helicobacter pylori-induced IL-1β secretion in innate immune cells is regulated by the NLRP3 inflammasome and requires the cag pathogenicity island.

Semper RP, Mejías-Luque R, Groß C, Anderl F, Müller A, Vieth M, Busch DH, Prazeres da Costa C, Ruland J, Groß O, Gerhard M.

J Immunol. 2014 Oct 1;193(7):3566-76. doi: 10.4049/jimmunol.1400362. Epub 2014 Aug 29.

41.

Involvement of Toll-like receptors on Helicobacter pylori-induced immunity.

Käbisch R, Mejías-Luque R, Gerhard M, Prinz C.

PLoS One. 2014 Aug 25;9(8):e104804. doi: 10.1371/journal.pone.0104804. eCollection 2014.

42.

Helicobacter pylori γ-glutamyltranspeptidase impairs T-lymphocyte function by compromising metabolic adaption through inhibition of cMyc and IRF4 expression.

Wüstner S, Mejías-Luque R, Koch MF, Rath E, Vieth M, Sieber SA, Haller D, Gerhard M.

Cell Microbiol. 2015 Jan;17(1):51-61. doi: 10.1111/cmi.12335. Epub 2014 Aug 30.

PMID:
25087912
43.

Effective treatment of allergic airway inflammation with Helicobacter pylori immunomodulators requires BATF3-dependent dendritic cells and IL-10.

Engler DB, Reuter S, van Wijck Y, Urban S, Kyburz A, Maxeiner J, Martin H, Yogev N, Waisman A, Gerhard M, Cover TL, Taube C, Müller A.

Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11810-5. doi: 10.1073/pnas.1410579111. Epub 2014 Jul 29.

44.

C/EBP homologous protein inhibits tissue repair in response to gut injury and is inversely regulated with chronic inflammation.

Waldschmitt N, Berger E, Rath E, Sartor RB, Weigmann B, Heikenwalder M, Gerhard M, Janssen KP, Haller D.

Mucosal Immunol. 2014 Nov;7(6):1452-66. doi: 10.1038/mi.2014.34. Epub 2014 May 21.

PMID:
24850428
45.

H. pylori virulence factors: influence on immune system and pathology.

Kalali B, Mejías-Luque R, Javaheri A, Gerhard M.

Mediators Inflamm. 2014;2014:426309. doi: 10.1155/2014/426309. Epub 2014 Jan 21. Review.

46.

Rearrangements of MYC gene facilitate risk stratification in diffuse large B-cell lymphoma patients treated with rituximab-CHOP.

Tzankov A, Xu-Monette ZY, Gerhard M, Visco C, Dirnhofer S, Gisin N, Dybkaer K, Orazi A, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Ponzoni M, Ferreri AJ, Ye Q, Winter JN, Farnen JP, Piris MA, Møller MB, You MJ, McDonnell T, Medeiros LJ, Young KH.

Mod Pathol. 2014 Jul;27(7):958-71. doi: 10.1038/modpathol.2013.214. Epub 2013 Dec 13.

47.

The stem cell factor SOX2 regulates the tumorigenic potential in human gastric cancer cells.

Hütz K, Mejías-Luque R, Farsakova K, Ogris M, Krebs S, Anton M, Vieth M, Schüller U, Schneider MR, Blum H, Wagner E, Jung A, Gerhard M.

Carcinogenesis. 2014 Apr;35(4):942-50. doi: 10.1093/carcin/bgt410. Epub 2013 Dec 9.

PMID:
24325912
48.

Helicobacter pylori cytotoxin-associated gene A impairs human dendritic cell maturation and function through IL-10-mediated activation of STAT3.

Kaebisch R, Mejías-Luque R, Prinz C, Gerhard M.

J Immunol. 2014 Jan 1;192(1):316-23. doi: 10.4049/jimmunol.1302476. Epub 2013 Nov 29.

49.

Helicobacter pylori antibody responses and evolution of precancerous gastric lesions in a Chinese population.

Pan KF, Formichella L, Zhang L, Zhang Y, Ma JL, Li ZX, Liu C, Wang YM, Goettner G, Ulm K, Classen M, You WC, Gerhard M.

Int J Cancer. 2014 May 1;134(9):2118-25. doi: 10.1002/ijc.28560. Epub 2013 Nov 7.

50.

Helicobacter pylori FliD protein is a highly sensitive and specific marker for serologic diagnosis of H. pylori infection.

Khalifeh Gholi M, Kalali B, Formichella L, Göttner G, Shamsipour F, Zarnani AH, Hosseini M, Busch DH, Shirazi MH, Gerhard M.

Int J Med Microbiol. 2013 Dec;303(8):618-23. doi: 10.1016/j.ijmm.2013.08.005. Epub 2013 Sep 3.

PMID:
24103649

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