Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 41

1.

Initial characterization of transgenic mice overexpressing human histamine H2 receptors.

Gergs U, Bernhardt G, Buchwalow I, Edler H, Froeba J, Keller M, Kirchhefer U, Koehler F, Misslinger N, Wache H, Neumann J.

J Pharmacol Exp Ther. 2019 Feb 6. pii: jpet.118.255711. doi: 10.1124/jpet.118.255711. [Epub ahead of print]

2.

Age-Dependent Protein Expression of Serine/Threonine Phosphatases and Their Inhibitors in the Human Cardiac Atrium.

Gergs U, Trapp T, Bushnaq H, Simm A, Silber RE, Neumann J.

Adv Med. 2019 Jan 2;2019:2675972. doi: 10.1155/2019/2675972. eCollection 2019.

3.

PP2A negatively regulates the hypertrophic response by dephosphorylating HDAC2 S394 in the heart.

Yoon S, Kook T, Min HK, Kwon DH, Cho YK, Kim M, Shin S, Joung H, Jeong SH, Lee S, Kang G, Park Y, Kim YS, Ahn Y, McMullen JR, Gergs U, Neumann J, Kim KK, Kim J, Nam KI, Kim YK, Kook H, Eom GH.

Exp Mol Med. 2018 Jul 26;50(7):83. doi: 10.1038/s12276-018-0121-2.

4.

Cardiovascular effects of cisapride and prucalopride on human 5-HT4 receptors in transgenic mice.

Keller N, Dhein S, Neumann J, Gergs U.

Naunyn Schmiedebergs Arch Pharmacol. 2018 Sep;391(9):975-985. doi: 10.1007/s00210-018-1519-z. Epub 2018 Jun 9.

PMID:
29947908
5.

Successful overexpression of wild-type inhibitor-2 of PP1 in cardiovascular cells.

Krause T, Grote-Wessels S, Balzer F, Boknik P, Gergs U, Kirchhefer U, Buchwalow IB, Müller FU, Schmitz W, Neumann J.

Naunyn Schmiedebergs Arch Pharmacol. 2018 Aug;391(8):859-873. doi: 10.1007/s00210-018-1515-3. Epub 2018 May 24.

PMID:
29797049
6.

Mechanism underlying the contractile activity of UTP in the mammalian heart.

Gergs U, Rothkirch D, Hofmann B, Treede H, Robaye B, Simm A, Müller CE, Neumann J.

Eur J Pharmacol. 2018 Jul 5;830:47-58. doi: 10.1016/j.ejphar.2018.04.013. Epub 2018 Apr 17.

PMID:
29673908
7.

Phenotyping of Mice with Heart Specific Overexpression of A2A-Adenosine Receptors: Evidence for Cardioprotective Effects of A2A-Adenosine Receptors.

Boknik P, Drzewiecki K, Eskandar J, Gergs U, Grote-Wessels S, Fabritz L, Kirchhof P, Müller FU, Stümpel F, Schmitz W, Zimmermann N, Kirchhefer U, Neumann J.

Front Pharmacol. 2018 Jan 22;9:13. doi: 10.3389/fphar.2018.00013. eCollection 2018.

8.

Protein phosphatase 5 regulates titin phosphorylation and function at a sarcomere-associated mechanosensor complex in cardiomyocytes.

Krysiak J, Unger A, Beckendorf L, Hamdani N, von Frieling-Salewsky M, Redfield MM, Dos Remedios CG, Sheikh F, Gergs U, Boknik P, Linke WA.

Nat Commun. 2018 Jan 17;9(1):262. doi: 10.1038/s41467-017-02483-3.

9.

Population Pharmacokinetics of Levofloxacin in Plasma and Bone of Patients Undergoing Hip or Knee Surgery.

Gergs U, Ihlefeld D, Clauss T, Weiss M, Pönicke K, Hofmann GO, Neumann J.

Clin Pharmacol Drug Dev. 2018 Sep;7(7):692-698. doi: 10.1002/cpdd.418. Epub 2017 Dec 18.

PMID:
29251833
10.

Pharmacological and physiological assessment of serotonin formation and degradation in isolated preparations from mouse and human hearts.

Gergs U, Jung F, Buchwalow IB, Hofmann B, Simm A, Treede H, Neumann J.

Am J Physiol Heart Circ Physiol. 2017 Dec 1;313(6):H1087-H1097. doi: 10.1152/ajpheart.00350.2017. Epub 2017 Sep 15.

11.

Desensitization of the human 5-HT4 receptor in isolated atria of transgenic mice.

Gergs U, Fritsche J, Fabian S, Christ J, Neumann J.

Naunyn Schmiedebergs Arch Pharmacol. 2017 Oct;390(10):987-996. doi: 10.1007/s00210-017-1403-2. Epub 2017 Jul 8.

PMID:
28689254
12.

Evidence for a functional role of calsequestrin 2 in mouse atrium.

Gergs U, Fahrion CM, Bock P, Fischer M, Wache H, Hauptmann S, Schmitz W, Neumann J.

Acta Physiol (Oxf). 2017 Mar;219(3):669-682. doi: 10.1111/apha.12766. Epub 2016 Aug 31.

PMID:
27484853
13.

Overexpression of protein phosphatase 2A in a murine model of chronic myocardial infarction leads to increased adverse remodeling but restores the regulation of β-catenin by glycogen synthase kinase 3β.

Hoehn M, Zhang Y, Xu J, Gergs U, Boknik P, Werdan K, Neumann J, Ebelt H.

Int J Cardiol. 2015 Mar 15;183:39-46. doi: 10.1016/j.ijcard.2015.01.087. Epub 2015 Jan 29.

PMID:
25662052
14.

Pharmacokinetics of ceftriaxone in plasma and bone of patients undergoing hip or knee surgery.

Gergs U, Clauss T, Ihlefeld D, Weiss M, Pönicke K, Hofmann GO, Neumann J.

J Pharm Pharmacol. 2014 Nov;66(11):1552-8. doi: 10.1111/jphp.12282. Epub 2014 Jun 19.

PMID:
24941934
15.

A positive inotropic effect of UTP in the human cardiac atrium.

Gergs U, Simm A, Bushnaq H, Silber RE, Neumann J.

Eur J Pharmacol. 2014 Feb 5;724:24-30. doi: 10.1016/j.ejphar.2013.12.022. Epub 2013 Dec 24.

PMID:
24370494
16.

Autonomic dysfunction in patients with arrhythmogenic right ventricular cardiomyopathy: biochemical evidence of altered signaling pathways.

Paul M, Meyborg M, Boknik P, Gergs U, Gerss J, Schmitz W, Breithardt G, Wichter T, Neumann J.

Pacing Clin Electrophysiol. 2014 Feb;37(2):173-8. doi: 10.1111/pace.12237. Epub 2013 Sep 11.

PMID:
24025189
17.

Human 5-HT₄receptor stimulation in atria of transgenic mice.

Gergs U, Böckler A, Ebelt H, Hauptmann S, Keller N, Otto V, Pönicke K, Schmitz W, Neumann J.

Naunyn Schmiedebergs Arch Pharmacol. 2013 May;386(5):357-67. doi: 10.1007/s00210-013-0831-x. Epub 2013 Jan 11.

PMID:
23307014
18.

On the presence of serotonin in mammalian cardiomyocytes.

Pönicke K, Gergs U, Buchwalow IB, Hauptmann S, Neumann J.

Mol Cell Biochem. 2012 Jun;365(1-2):301-12. doi: 10.1007/s11010-012-1270-6. Epub 2012 Feb 25.

PMID:
22367115
19.

Protein phosphatase 2A affects myofilament contractility in non-failing but not in failing human myocardium.

Wijnker PJ, Boknik P, Gergs U, Müller FU, Neumann J, dos Remedios C, Schmitz W, Sindermann JR, Stienen GJ, van der Velden J, Kirchhefer U.

J Muscle Res Cell Motil. 2011 Nov;32(3):221-33. doi: 10.1007/s10974-011-9261-x. Epub 2011 Sep 30.

20.

Sarcoplasmic reticulum Ca2+ release in neonatal rat cardiac myocytes.

Gergs U, Kirchhefer U, Buskase J, Kiele-Dunsche K, Buchwalow IB, Jones LR, Schmitz W, Traub O, Neumann J.

J Mol Cell Cardiol. 2011 Nov;51(5):682-8. doi: 10.1016/j.yjmcc.2011.08.007. Epub 2011 Aug 17.

PMID:
21871897
21.

Autonomic dysfunction in patients with Brugada syndrome: further biochemical evidence of altered signaling pathways.

Paul M, Meyborg M, Boknik P, Gergs U, Schmitz W, Breithardt G, Wichter T, Neumann J.

Pacing Clin Electrophysiol. 2011 Sep;34(9):1147-53. doi: 10.1111/j.1540-8159.2011.03127.x. Epub 2011 May 23.

PMID:
21605134
22.

Inotropic effects of ivabradine in the mammalian heart.

Boldt A, Gergs U, Pönicke K, Simm A, Silber RE, Neumann J.

Pharmacology. 2010;86(5-6):249-58. doi: 10.1159/000320454. Epub 2010 Oct 21.

PMID:
20962545
23.

Basis for MAP4 dephosphorylation-related microtubule network densification in pressure overload cardiac hypertrophy.

Cheng G, Takahashi M, Shunmugavel A, Wallenborn JG, DePaoli-Roach AA, Gergs U, Neumann J, Kuppuswamy D, Menick DR, Cooper G 4th.

J Biol Chem. 2010 Dec 3;285(49):38125-40. doi: 10.1074/jbc.M110.148650. Epub 2010 Oct 2.

24.

Modulation of cardiac contractility by serine/threonine protein phosphatase type 5.

Gergs U, Boknik P, Buchwalow IB, Fabritz L, Gründker N, Kucerova D, Matus M, Werner F, Schmitz W, Neumann J.

Int J Cardiol. 2012 Jan 26;154(2):116-21. doi: 10.1016/j.ijcard.2010.09.009. Epub 2010 Sep 28.

PMID:
20875921
25.

Increased transient receptor potential vanilloid type 1 (TRPV1) channel expression in hypertrophic heart.

Thilo F, Liu Y, Schulz N, Gergs U, Neumann J, Loddenkemper C, Gollasch M, Tepel M.

Biochem Biophys Res Commun. 2010 Oct 8;401(1):98-103. doi: 10.1016/j.bbrc.2010.09.017. Epub 2010 Sep 15.

PMID:
20833132
26.

Losartan reduces mortality in a genetic model of heart failure.

Günther S, Baba HA, Hauptmann S, Holzhausen HJ, Grossmann C, Punkt K, Kusche T, Jones LR, Gergs U, Neumann J.

Naunyn Schmiedebergs Arch Pharmacol. 2010 Sep;382(3):265-78. doi: 10.1007/s00210-010-0544-3. Epub 2010 Aug 10.

PMID:
20697885
27.

Cardiac overexpression of the human 5-HT4 receptor in mice.

Gergs U, Baumann M, Böckler A, Buchwalow IB, Ebelt H, Fabritz L, Hauptmann S, Keller N, Kirchhof P, Klöckner U, Pönicke K, Rueckschloss U, Schmitz W, Werner F, Neumann J.

Am J Physiol Heart Circ Physiol. 2010 Sep;299(3):H788-98. doi: 10.1152/ajpheart.00691.2009. Epub 2010 Jul 16.

28.

Inotropic effects of L-lysine in the mammalian heart.

Boldt A, Gergs U, Frenker J, Simm A, Silber RE, Klöckner U, Neumann J.

Naunyn Schmiedebergs Arch Pharmacol. 2009 Oct;380(4):293-301. doi: 10.1007/s00210-009-0439-3. Epub 2009 Aug 7.

PMID:
19662383
29.

A positive inotropic effect of adenosine in cardiac preparations of right atria from diseased human hearts.

Gergs U, Boknik P, Schmitz W, Simm A, Silber RE, Neumann J.

Naunyn Schmiedebergs Arch Pharmacol. 2009 May;379(5):533-40. doi: 10.1007/s00210-008-0374-8. Epub 2008 Nov 27.

PMID:
19037631
30.

Phosphorylation of phospholamban and troponin I through 5-HT4 receptors in the isolated human atrium.

Gergs U, Neumann J, Simm A, Silber RE, Remmers FO, Läer S.

Naunyn Schmiedebergs Arch Pharmacol. 2009 Apr;379(4):349-59. doi: 10.1007/s00210-008-0371-y. Epub 2008 Nov 11.

PMID:
19002436
31.

Inhibitor-2 prevents protein phosphatase 1-induced cardiac hypertrophy and mortality.

Brüchert N, Mavila N, Boknik P, Baba HA, Fabritz L, Gergs U, Kirchhefer U, Kirchhof P, Matus M, Schmitz W, DePaoli-Roach AA, Neumann J.

Am J Physiol Heart Circ Physiol. 2008 Oct;295(4):H1539-46. doi: 10.1152/ajpheart.00515.2008. Epub 2008 Aug 8.

32.

A positive inotropic effect of ATP in the human cardiac atrium.

Gergs U, Boknik P, Schmitz W, Simm A, Silber RE, Neumann J.

Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1716-23. doi: 10.1152/ajpheart.00945.2007. Epub 2008 Feb 8.

33.

On the role of junctin in cardiac Ca2+ handling, contractility, and heart failure.

Gergs U, Berndt T, Buskase J, Jones LR, Kirchhefer U, Müller FU, Schlüter KD, Schmitz W, Neumann J.

Am J Physiol Heart Circ Physiol. 2007 Jul;293(1):H728-34. Epub 2007 Mar 30.

34.

Reduced expression of Ca2+-regulating proteins in the upper gastrointestinal tract of patients with achalasia.

Fischer H, Fischer J, Boknik P, Gergs U, Schmitz W, Domschke W, Konturek JW, Neumann J.

World J Gastroenterol. 2006 Oct 7;12(37):6002-7.

35.

Comparison of contractile responses in isolated mouse aorta and pulmonary artery: Influence of strain and sex.

Knapp J, Aleth S, Balzer F, Gergs U, Schmitz W, Neumann J.

J Cardiovasc Pharmacol. 2006 Jul;48(1):820-6.

PMID:
16891910
36.

Overexpression of the catalytic subunit of protein phosphatase 2A impairs cardiac function.

Gergs U, Boknik P, Buchwalow I, Fabritz L, Matus M, Justus I, Hanske G, Schmitz W, Neumann J.

J Biol Chem. 2004 Sep 24;279(39):40827-34. Epub 2004 Jul 6.

37.

Tumor necrosis factor-alpha at acute myocardial infarction in rats and effects on cardiac fibroblasts.

Jacobs M, Staufenberger S, Gergs U, Meuter K, Brandstätter K, Hafner M, Ertl G, Schorb W.

J Mol Cell Cardiol. 1999 Nov;31(11):1949-59.

PMID:
10591022
38.

Immunochemical characterization of the gap junction protein connexin45 in mouse kidney and transfected human HeLa cells.

Butterweck A, Gergs U, Elfgang C, Willecke K, Traub O.

J Membr Biol. 1994 Sep;141(3):247-56.

PMID:
7807524
39.

Calcium- and ATP-dependent changes in myosin mass distribution of glycerinated rabbit psoas muscle.

Chaplain RA, Gergs U.

Biochem Biophys Res Commun. 1974 Nov 27;61(2):527-24. No abstract available.

PMID:
4281657
40.

Regulatory effects of ATP and calcium on the myofibrillar ATPase of frog sartorius muscle.

Chaplain RA, Gergs U.

Biochem Biophys Res Commun. 1974 Nov 6;61(1):297-305. No abstract available.

PMID:
4280308
41.

Pre-steady state kinetics of rabbit myosin- and actomyosin-ATPase.

Chaplain RA, Gergs U.

FEBS Lett. 1974 Aug 1;43(3):277-80. No abstract available.

Supplemental Content

Support Center