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Items: 1 to 50 of 109

1.

Reconstruction of 1,000 Projection Neurons Reveals New Cell Types and Organization of Long-Range Connectivity in the Mouse Brain.

Winnubst J, Bas E, Ferreira TA, Wu Z, Economo MN, Edson P, Arthur BJ, Bruns C, Rokicki K, Schauder D, Olbris DJ, Murphy SD, Ackerman DG, Arshadi C, Baldwin P, Blake R, Elsayed A, Hasan M, Ramirez D, Dos Santos B, Weldon M, Zafar A, Dudman JT, Gerfen CR, Hantman AW, Korff W, Sternson SM, Spruston N, Svoboda K, Chandrashekar J.

Cell. 2019 Sep 19;179(1):268-281.e13. doi: 10.1016/j.cell.2019.07.042. Epub 2019 Sep 5.

PMID:
31495573
2.

Automatic navigation system for the mouse brain.

Tappan SJ, Eastwood BS, O'Connor N, Wang Q, Ng L, Feng D, Hooks BM, Gerfen CR, Hof PR, Schmitz C, Glaser JR.

J Comp Neurol. 2019 Sep 1;527(13):2200-2211. doi: 10.1002/cne.24635. Epub 2019 Feb 24.

PMID:
30635922
3.

Whole mouse brain reconstruction and registration to a reference atlas with standard histochemical processing of coronal sections.

Eastwood BS, Hooks BM, Paletzki RF, O'Connor NJ, Glaser JR, Gerfen CR.

J Comp Neurol. 2019 Sep 1;527(13):2170-2178. doi: 10.1002/cne.24602. Epub 2019 Jan 2. Review.

PMID:
30549030
4.

Distinct descending motor cortex pathways and their roles in movement.

Economo MN, Viswanathan S, Tasic B, Bas E, Winnubst J, Menon V, Graybuck LT, Nguyen TN, Smith KA, Yao Z, Wang L, Gerfen CR, Chandrashekar J, Zeng H, Looger LL, Svoboda K.

Nature. 2018 Nov;563(7729):79-84. doi: 10.1038/s41586-018-0642-9. Epub 2018 Oct 31.

PMID:
30382200
5.

Author Correction: Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area.

Hooks BM, Papale AE, Paletzki RF, Feroze MW, Eastwood BS, Couey JJ, Winnubst J, Chandrashekar J, Gerfen CR.

Nat Commun. 2018 Oct 12;9(1):4317. doi: 10.1038/s41467-018-06928-1.

6.

Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area.

Hooks BM, Papale AE, Paletzki RF, Feroze MW, Eastwood BS, Couey JJ, Winnubst J, Chandrashekar J, Gerfen CR.

Nat Commun. 2018 Sep 3;9(1):3549. doi: 10.1038/s41467-018-05780-7. Erratum in: Nat Commun. 2018 Oct 12;9(1):4317.

7.

Activation of Striatal Neurons Causes a Perceptual Decision Bias during Visual Change Detection in Mice.

Wang L, Rangarajan KV, Gerfen CR, Krauzlis RJ.

Neuron. 2018 May 2;98(3):669. doi: 10.1016/j.neuron.2018.04.026. No abstract available.

8.

Activation of Striatal Neurons Causes a Perceptual Decision Bias during Visual Change Detection in Mice.

Wang L, Rangarajan KV, Gerfen CR, Krauzlis RJ.

Neuron. 2018 Mar 21;97(6):1369-1381.e5. doi: 10.1016/j.neuron.2018.01.049. Epub 2018 Mar 1. Erratum in: Neuron. 2018 May 2;98 (3):669.

9.

NCS-Rapgef2, the Protein Product of the Neuronal Rapgef2 Gene, Is a Specific Activator of D1 Dopamine Receptor-Dependent ERK Phosphorylation in Mouse Brain.

Jiang SZ, Xu W, Emery AC, Gerfen CR, Eiden MV, Eiden LE.

eNeuro. 2017 Sep 25;4(5). pii: ENEURO.0248-17.2017. doi: 10.1523/ENEURO.0248-17.2017. eCollection 2017 Sep-Oct. Erratum in: eNeuro. 2018 Oct 15;5(5):.

10.

Deconstruction of Corticospinal Circuits for Goal-Directed Motor Skills.

Wang X, Liu Y, Li X, Zhang Z, Yang H, Zhang Y, Williams PR, Alwahab NSA, Kapur K, Yu B, Zhang Y, Chen M, Ding H, Gerfen CR, Wang KH, He Z.

Cell. 2017 Oct 5;171(2):440-455.e14. doi: 10.1016/j.cell.2017.08.014. Epub 2017 Sep 21.

11.

Maintenance of persistent activity in a frontal thalamocortical loop.

Guo ZV, Inagaki HK, Daie K, Druckmann S, Gerfen CR, Svoboda K.

Nature. 2017 May 11;545(7653):181-186. doi: 10.1038/nature22324. Epub 2017 May 3.

12.

Striatopallidal dysfunction underlies repetitive behavior in Shank3-deficient model of autism.

Wang W, Li C, Chen Q, van der Goes MS, Hawrot J, Yao AY, Gao X, Lu C, Zang Y, Zhang Q, Lyman K, Wang D, Guo B, Wu S, Gerfen CR, Fu Z, Feng G.

J Clin Invest. 2017 May 1;127(5):1978-1990. doi: 10.1172/JCI87997. Epub 2017 Apr 17.

13.

Long distance projections of cortical pyramidal neurons.

Gerfen CR, Economo MN, Chandrashekar J.

J Neurosci Res. 2018 Sep;96(9):1467-1475. doi: 10.1002/jnr.23978. Epub 2016 Nov 12. Review.

14.

A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons.

Tervo DG, Hwang BY, Viswanathan S, Gaj T, Lavzin M, Ritola KD, Lindo S, Michael S, Kuleshova E, Ojala D, Huang CC, Gerfen CR, Schiller J, Dudman JT, Hantman AW, Looger LL, Schaffer DV, Karpova AY.

Neuron. 2016 Oct 19;92(2):372-382. doi: 10.1016/j.neuron.2016.09.021. Epub 2016 Oct 6.

15.

Dopamine D2 receptors gate generalization of conditioned threat responses through mTORC1 signaling in the extended amygdala.

De Bundel D, Zussy C, Espallergues J, Gerfen CR, Girault JA, Valjent E.

Mol Psychiatry. 2016 Nov;21(11):1545-1553. doi: 10.1038/mp.2015.210. Epub 2016 Jan 19.

16.

Spatially Compact Neural Clusters in the Dorsal Striatum Encode Locomotion Relevant Information.

Barbera G, Liang B, Zhang L, Gerfen CR, Culurciello E, Chen R, Li Y, Lin DT.

Neuron. 2016 Oct 5;92(1):202-213. doi: 10.1016/j.neuron.2016.08.037. Epub 2016 Sep 22.

17.

Striosome-dendron bouquets highlight a unique striatonigral circuit targeting dopamine-containing neurons.

Crittenden JR, Tillberg PW, Riad MH, Shima Y, Gerfen CR, Curry J, Housman DE, Nelson SB, Boyden ES, Graybiel AM.

Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11318-11323. Epub 2016 Sep 19.

18.

Genetic-Based Dissection Unveils the Inputs and Outputs of Striatal Patch and Matrix Compartments.

Smith JB, Klug JR, Ross DL, Howard CD, Hollon NG, Ko VI, Hoffman H, Callaway EM, Gerfen CR, Jin X.

Neuron. 2016 Sep 7;91(5):1069-1084. doi: 10.1016/j.neuron.2016.07.046. Epub 2016 Aug 25.

19.

A platform for brain-wide imaging and reconstruction of individual neurons.

Economo MN, Clack NG, Lavis LD, Gerfen CR, Svoboda K, Myers EW, Chandrashekar J.

Elife. 2016 Jan 20;5:e10566. doi: 10.7554/eLife.10566.

21.

Whole Mouse Brain Image Reconstruction from Serial Coronal Sections Using FIJI (ImageJ).

Paletzki R, Gerfen CR.

Curr Protoc Neurosci. 2015 Oct 1;73:1.25.1-1.25.21. doi: 10.1002/0471142301.ns0125s73.

PMID:
26426384
22.

High-performance probes for light and electron microscopy.

Viswanathan S, Williams ME, Bloss EB, Stasevich TJ, Speer CM, Nern A, Pfeiffer BD, Hooks BM, Li WP, English BP, Tian T, Henry GL, Macklin JJ, Patel R, Gerfen CR, Zhuang X, Wang Y, Rubin GM, Looger LL.

Nat Methods. 2015 Jun;12(6):568-76. doi: 10.1038/nmeth.3365. Epub 2015 Apr 27.

23.

A direct GABAergic output from the basal ganglia to frontal cortex.

Saunders A, Oldenburg IA, Berezovskii VK, Johnson CA, Kingery ND, Elliott HL, Xie T, Gerfen CR, Sabatini BL.

Nature. 2015 May 7;521(7550):85-9. doi: 10.1038/nature14179. Epub 2015 Mar 4.

24.

A motor cortex circuit for motor planning and movement.

Li N, Chen TW, Guo ZV, Gerfen CR, Svoboda K.

Nature. 2015 Mar 5;519(7541):51-6. doi: 10.1038/nature14178. Epub 2015 Feb 25.

PMID:
25731172
25.

Phasic dopamine neuron activity elicits unique mesofrontal plasticity in adolescence.

Mastwal S, Ye Y, Ren M, Jimenez DV, Martinowich K, Gerfen CR, Wang KH.

J Neurosci. 2014 Jul 16;34(29):9484-96. doi: 10.1523/JNEUROSCI.1114-14.2014.

26.

A mesoscale connectome of the mouse brain.

Oh SW, Harris JA, Ng L, Winslow B, Cain N, Mihalas S, Wang Q, Lau C, Kuan L, Henry AM, Mortrud MT, Ouellette B, Nguyen TN, Sorensen SA, Slaughterbeck CR, Wakeman W, Li Y, Feng D, Ho A, Nicholas E, Hirokawa KE, Bohn P, Joines KM, Peng H, Hawrylycz MJ, Phillips JW, Hohmann JG, Wohnoutka P, Gerfen CR, Koch C, Bernard A, Dang C, Jones AR, Zeng H.

Nature. 2014 Apr 10;508(7495):207-14. doi: 10.1038/nature13186. Epub 2014 Apr 2.

27.

GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits.

Gerfen CR, Paletzki R, Heintz N.

Neuron. 2013 Dec 18;80(6):1368-83. doi: 10.1016/j.neuron.2013.10.016.

28.

Distribution and compartmental organization of GABAergic medium-sized spiny neurons in the mouse nucleus accumbens.

Gangarossa G, Espallergues J, de Kerchove d'Exaerde A, El Mestikawy S, Gerfen CR, Hervé D, Girault JA, Valjent E.

Front Neural Circuits. 2013 Feb 19;7:22. doi: 10.3389/fncir.2013.00022. eCollection 2013.

29.

Hypothalamic and other connections with dorsal CA2 area of the mouse hippocampus.

Cui Z, Gerfen CR, Young WS 3rd.

J Comp Neurol. 2013 Jun 1;521(8):1844-66. doi: 10.1002/cne.23263.

30.

Modulation of striatal projection systems by dopamine.

Gerfen CR, Surmeier DJ.

Annu Rev Neurosci. 2011;34:441-66. doi: 10.1146/annurev-neuro-061010-113641. Review.

31.

Identification of RanBP 9/10 as interacting partners for protein kinase C (PKC) gamma/delta and the D1 dopamine receptor: regulation of PKC-mediated receptor phosphorylation.

Rex EB, Rankin ML, Yang Y, Lu Q, Gerfen CR, Jose PA, Sibley DR.

Mol Pharmacol. 2010 Jul;78(1):69-80. doi: 10.1124/mol.110.063727. Epub 2010 Apr 15.

32.

Priming for l-dopa-induced dyskinesia in Parkinson's disease: a feature inherent to the treatment or the disease?

Nadjar A, Gerfen CR, Bezard E.

Prog Neurobiol. 2009 Jan 12;87(1):1-9. doi: 10.1016/j.pneurobio.2008.09.013. Epub 2008 Sep 30. Review.

34.

Basic neuroanatomical methods.

Gerfen CR.

Curr Protoc Neurosci. 2003 Aug;Chapter 1:Unit 1.1. doi: 10.1002/0471142301.ns0101s23.

PMID:
18428576
35.

Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs.

Gong S, Doughty M, Harbaugh CR, Cummins A, Hatten ME, Heintz N, Gerfen CR.

J Neurosci. 2007 Sep 12;27(37):9817-23. No abstract available.

36.

Increased vulnerability of nigrostriatal terminals in DJ-1-deficient mice is mediated by the dopamine transporter.

Manning-Boğ AB, Caudle WM, Perez XA, Reaney SH, Paletzki R, Isla MZ, Chou VP, McCormack AL, Miller GW, Langston JW, Gerfen CR, Dimonte DA.

Neurobiol Dis. 2007 Aug;27(2):141-50. Epub 2007 May 3.

PMID:
17560790
38.

Indirect-pathway neurons lose their spines in Parkinson disease.

Gerfen CR.

Nat Neurosci. 2006 Feb;9(2):157-8. No abstract available.

PMID:
16439979
39.

Reversal of supersensitive striatal dopamine D1 receptor signaling and extracellular signal-regulated kinase activity in dopamine-deficient mice.

Kim DS, Palmiter RD, Cummins A, Gerfen CR.

Neuroscience. 2006;137(4):1381-8. Epub 2006 Jan 4.

PMID:
16388913
40.

Coincident stimulation of convergent cortical inputs enhances immediate early gene induction in the striatum.

Miyachi S, Hasegawa YT, Gerfen CR.

Neuroscience. 2005;134(3):1013-22.

PMID:
15978736
41.
42.
43.

Molecular effects of dopamine on striatal-projection pathways.

Gerfen CR.

Trends Neurosci. 2000 Oct;23(10 Suppl):S64-70. Review.

PMID:
11052222
44.
45.

Dopamine-mediated gene regulation in models of Parkinson's disease.

Gerfen CR.

Ann Neurol. 2000 Apr;47(4 Suppl 1):S42-50; discussion S50-2. Review.

PMID:
10762131
46.
47.
49.

Role of dynorphin and enkephalin in the regulation of striatal output pathways and behavior.

Steiner H, Gerfen CR.

Exp Brain Res. 1998 Nov;123(1-2):60-76. Review.

PMID:
9835393
50.

Expression of GTPase-deficient Gialpha2 results in translocation of cytoplasmic RGS4 to the plasma membrane.

Druey KM, Sullivan BM, Brown D, Fischer ER, Watson N, Blumer KJ, Gerfen CR, Scheschonka A, Kehrl JH.

J Biol Chem. 1998 Jul 17;273(29):18405-10.

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