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Items: 1 to 50 of 116

1.

Hydrogel vehicles for sequential delivery of protein drugs to promote vascular regeneration.

Wei Z, Volkova E, Blatchley MR, Gerecht S.

Adv Drug Deliv Rev. 2019 Aug 14. pii: S0169-409X(19)30141-3. doi: 10.1016/j.addr.2019.08.005. [Epub ahead of print]

PMID:
31421149
2.

Regenerative and durable small-diameter graft as an arterial conduit.

Elliott MB, Ginn B, Fukunishi T, Bedja D, Suresh A, Chen T, Inoue T, Dietz HC, Santhanam L, Mao HQ, Hibino N, Gerecht S.

Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):12710-12719. doi: 10.1073/pnas.1905966116. Epub 2019 Jun 10.

PMID:
31182572
3.

Chipping Away at Blood-Brain-Barrier Modeling.

Jamieson JJ, Gerecht S.

Cell Stem Cell. 2019 Jun 6;24(6):831-832. doi: 10.1016/j.stem.2019.05.014.

PMID:
31173708
4.

Role of iPSC-derived pericytes on barrier function of iPSC-derived brain microvascular endothelial cells in 2D and 3D.

Jamieson JJ, Linville RM, Ding YY, Gerecht S, Searson PC.

Fluids Barriers CNS. 2019 Jun 6;16(1):15. doi: 10.1186/s12987-019-0136-7.

5.

Engineering an Artificial T-Cell Stimulating Matrix for Immunotherapy.

Hickey JW, Dong Y, Chung JW, Salathe SF, Pruitt HC, Li X, Chang C, Fraser AK, Bessell CA, Ewald AJ, Gerecht S, Mao HQ, Schneck JP.

Adv Mater. 2019 Jun;31(23):e1807359. doi: 10.1002/adma.201807359. Epub 2019 Apr 10.

PMID:
30968468
6.

Hypoxia and matrix viscoelasticity sequentially regulate endothelial progenitor cluster-based vasculogenesis.

Blatchley MR, Hall F, Wang S, Pruitt HC, Gerecht S.

Sci Adv. 2019 Mar 20;5(3):eaau7518. doi: 10.1126/sciadv.aau7518. eCollection 2019 Mar.

7.

A Feedback Loop between Hypoxia and Matrix Stress Relaxation Increases Oxygen-Axis Migration and Metastasis in Sarcoma.

Lewis DM, Pruitt H, Jain N, Ciccaglione M, McCaffery JM, Xia Z, Weber K, Eisinger-Mathason TSK, Gerecht S.

Cancer Res. 2019 Apr 15;79(8):1981-1995. doi: 10.1158/0008-5472.CAN-18-1984. Epub 2019 Feb 18.

PMID:
30777851
8.

Collagen fiber structure guides 3D motility of cytotoxic T lymphocytes.

Pruitt HC, Lewis D, Ciccaglione M, Connor S, Smith Q, Hickey JW, Schneck JP, Gerecht S.

Matrix Biol. 2019 Feb 16. pii: S0945-053X(18)30458-X. doi: 10.1016/j.matbio.2019.02.003. [Epub ahead of print]

PMID:
30776427
9.

Pericytes Derived from Human Pluripotent Stem Cells.

Jamieson J, Macklin B, Gerecht S.

Adv Exp Med Biol. 2018;1109:111-124. doi: 10.1007/978-3-030-02601-1_9. Review.

PMID:
30523593
10.

Engineered Heart Slice Model of Arrhythmogenic Cardiomyopathy Using Plakophilin-2 Mutant Myocytes.

Blazeski A, Lowenthal J, Wang Y, Teuben R, Zhu R, Gerecht S, Tomaselli G, Tung L.

Tissue Eng Part A. 2019 May;25(9-10):725-735. doi: 10.1089/ten.TEA.2018.0272. Epub 2019 Feb 15.

PMID:
30520705
11.

A self-healing hydrogel as an injectable instructive carrier for cellular morphogenesis.

Wei Z, Gerecht S.

Biomaterials. 2018 Dec;185:86-96. doi: 10.1016/j.biomaterials.2018.09.003. Epub 2018 Sep 7.

12.

Differential HDAC6 Activity Modulates Ciliogenesis and Subsequent Mechanosensing of Endothelial Cells Derived from Pluripotent Stem Cells.

Smith Q, Macklin B, Chan XY, Jones H, Trempel M, Yoder MC, Gerecht S.

Cell Rep. 2018 Aug 14;24(7):1930. doi: 10.1016/j.celrep.2018.08.005. No abstract available.

13.

Acellular and cellular approaches to improve diabetic wound healing.

Cho H, Blatchley MR, Duh EJ, Gerecht S.

Adv Drug Deliv Rev. 2018 Aug 1. pii: S0169-409X(18)30193-5. doi: 10.1016/j.addr.2018.07.019. [Epub ahead of print] Review.

PMID:
30075168
14.

Differential HDAC6 Activity Modulates Ciliogenesis and Subsequent Mechanosensing of Endothelial Cells Derived from Pluripotent Stem Cells.

Smith Q, Macklin B, Chan XY, Jones H, Trempel M, Yoder MC, Gerecht S.

Cell Rep. 2018 Jul 24;24(4):895-908.e6. doi: 10.1016/j.celrep.2018.06.083. Erratum in: Cell Rep. 2018 Aug 14;24(7):1930.

15.

Cytoskeletal tension regulates mesodermal spatial organization and subsequent vascular fate.

Smith Q, Rochman N, Carmo AM, Vig D, Chan XY, Sun S, Gerecht S.

Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8167-8172. doi: 10.1073/pnas.1808021115. Epub 2018 Jul 23.

16.

Microfluidic platform for the real time measurement and observation of endothelial barrier function under shear stress.

Lewis DM, Mavrogiannis N, Gagnon Z, Gerecht S.

Biomicrofluidics. 2018 May 15;12(4):042202. doi: 10.1063/1.5026901. eCollection 2018 Jul.

17.

Engineering the human blood-brain barrier in vitro.

Jamieson JJ, Searson PC, Gerecht S.

J Biol Eng. 2017 Dec 4;11:37. doi: 10.1186/s13036-017-0076-1. eCollection 2017. Review.

18.

Human Pluripotent Stem Cells to Engineer Blood Vessels.

Chan XY, Elliott MB, Macklin B, Gerecht S.

Adv Biochem Eng Biotechnol. 2018;163:147-168. doi: 10.1007/10_2017_28. Review.

PMID:
29090328
19.

Sex differences in the mitochondrial bioenergetics of astrocytes but not microglia at a physiologically relevant brain oxygen tension.

Jaber SM, Bordt EA, Bhatt NM, Lewis DM, Gerecht S, Fiskum G, Polster BM.

Neurochem Int. 2018 Jul;117:82-90. doi: 10.1016/j.neuint.2017.09.003. Epub 2017 Sep 6.

20.

Integrin binding: Sticking around vessels.

Blatchley MR, Gerecht S.

Nat Mater. 2017 Aug 29;16(9):881-883. doi: 10.1038/nmat4977. No abstract available.

PMID:
28850117
21.

O2-controllable hydrogels for studying cellular responses to hypoxic gradients in three dimensions in vitro and in vivo.

Lewis DM, Blatchley MR, Park KM, Gerecht S.

Nat Protoc. 2017 Aug;12(8):1620-1638. doi: 10.1038/nprot.2017.059. Epub 2017 Jul 20.

22.

Bioinspired Hydrogels to Engineer Cancer Microenvironments.

Park KM, Lewis D, Gerecht S.

Annu Rev Biomed Eng. 2017 Jun 21;19:109-133. doi: 10.1146/annurev-bioeng-071516-044619. Review.

23.

Compliant substratum guides endothelial commitment from human pluripotent stem cells.

Smith Q, Chan XY, Carmo AM, Trempel M, Saunders M, Gerecht S.

Sci Adv. 2017 May 31;3(5):e1602883. doi: 10.1126/sciadv.1602883. eCollection 2017 May.

24.

Dual Cross-Linked Biofunctional and Self-Healing Networks to Generate User-Defined Modular Gradient Hydrogel Constructs.

Wei Z, Lewis DM, Xu Y, Gerecht S.

Adv Healthc Mater. 2017 Aug;6(16). doi: 10.1002/adhm.201700523. Epub 2017 May 23.

PMID:
28544647
25.

Enhanced elastin synthesis and maturation in human vascular smooth muscle tissue derived from induced-pluripotent stem cells.

Eoh JH, Shen N, Burke JA, Hinderer S, Xia Z, Schenke-Layland K, Gerecht S.

Acta Biomater. 2017 Apr 1;52:49-59. doi: 10.1016/j.actbio.2017.01.083. Epub 2017 Feb 3.

PMID:
28163239
26.

Diffusing Colloidal Probes of kT-Scale Biomaterial-Cell Interactions.

Duncan GA, Gerecht S, Fairbrother DH, Bevan MA.

Langmuir. 2016 Nov 22;32(46):12212-12220. Epub 2016 Nov 7.

PMID:
27788001
27.

Stem Cell Fate Is a Touchy Subject.

Smith Q, Gerecht S.

Cell Stem Cell. 2016 Sep 1;19(3):289-90. doi: 10.1016/j.stem.2016.08.015.

28.

Engineered Biopolymeric Scaffolds for Chronic Wound Healing.

Dickinson LE, Gerecht S.

Front Physiol. 2016 Aug 5;7:341. doi: 10.3389/fphys.2016.00341. eCollection 2016. Review.

29.

Intratumoral oxygen gradients mediate sarcoma cell invasion.

Lewis DM, Park KM, Tang V, Xu Y, Pak K, Eisinger-Mathason TS, Simon MC, Gerecht S.

Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):9292-7. doi: 10.1073/pnas.1605317113. Epub 2016 Aug 2.

30.

Engineered human vascularized constructs accelerate diabetic wound healing.

Shen YI, Cho H, Papa AE, Burke JA, Chan XY, Duh EJ, Gerecht S.

Biomaterials. 2016 Sep;102:107-19. doi: 10.1016/j.biomaterials.2016.06.009. Epub 2016 Jun 4.

PMID:
27328431
31.

Human Brain Microvascular Endothelial Cells Derived from the BC1 iPS Cell Line Exhibit a Blood-Brain Barrier Phenotype.

Katt ME, Xu ZS, Gerecht S, Searson PC.

PLoS One. 2016 Apr 12;11(4):e0152105. doi: 10.1371/journal.pone.0152105. eCollection 2016.

32.

Fibronectin Deposition Participates in Extracellular Matrix Assembly and Vascular Morphogenesis.

Hielscher A, Ellis K, Qiu C, Porterfield J, Gerecht S.

PLoS One. 2016 Jan 26;11(1):e0147600. doi: 10.1371/journal.pone.0147600. eCollection 2016.

33.

To Serve and Protect: Hydrogels to Improve Stem Cell-Based Therapies.

Burdick JA, Mauck RL, Gerecht S.

Cell Stem Cell. 2016 Jan 7;18(1):13-5. doi: 10.1016/j.stem.2015.12.004.

34.

Endothelial progenitor cell recruitment in a microfluidic vascular model.

Lewis DM, Abaci HE, Xu Y, Gerecht S.

Biofabrication. 2015 Dec 22;7(4):045010. doi: 10.1088/1758-5090/7/4/045010.

PMID:
26693599
35.

Designer Hydrogels for Precision Control of Oxygen Tension and Mechanical Properties.

Blatchley M, Park KM, Gerecht S.

J Mater Chem B. 2015 Oct 28;3(40):7939-7949. Epub 2015 Aug 5.

36.

Three-Dimensional Vascular Network Assembly From Diabetic Patient-Derived Induced Pluripotent Stem Cells.

Chan XY, Black R, Dickerman K, Federico J, Lévesque M, Mumm J, Gerecht S.

Arterioscler Thromb Vasc Biol. 2015 Dec;35(12):2677-85. doi: 10.1161/ATVBAHA.115.306362. Epub 2015 Oct 8.

37.

Stem cell-derived vasculature: A potent and multidimensional technology for basic research, disease modeling, and tissue engineering.

Lowenthal J, Gerecht S.

Biochem Biophys Res Commun. 2016 May 6;473(3):733-42. doi: 10.1016/j.bbrc.2015.09.127. Epub 2015 Sep 30. Review.

38.

Review: in vitro microvessel models.

Bogorad MI, DeStefano J, Karlsson J, Wong AD, Gerecht S, Searson PC.

Lab Chip. 2015 Nov 21;15(22):4242-55. doi: 10.1039/c5lc00832h. Review.

PMID:
26364747
39.

Acellular Hydrogels for Regenerative Burn Wound Healing: Translation from a Porcine Model.

Shen YI, Song HG, Papa A, Burke J, Volk SW, Gerecht S.

J Invest Dermatol. 2015 Oct;135(10):2519-2529. doi: 10.1038/jid.2015.182. Epub 2015 May 8.

40.

Stochasticity and Spatial Interaction Govern Stem Cell Differentiation Dynamics.

Smith Q, Stukalin E, Kusuma S, Gerecht S, Sun SX.

Sci Rep. 2015 Jul 31;5:12617. doi: 10.1038/srep12617.

41.

Biomechanical strain induces elastin and collagen production in human pluripotent stem cell-derived vascular smooth muscle cells.

Wanjare M, Agarwal N, Gerecht S.

Am J Physiol Cell Physiol. 2015 Aug 15;309(4):C271-81. doi: 10.1152/ajpcell.00366.2014. Epub 2015 Jun 24.

42.

Deregulation of the Hippo pathway in soft-tissue sarcoma promotes FOXM1 expression and tumorigenesis.

Eisinger-Mathason TS, Mucaj V, Biju KM, Nakazawa MS, Gohil M, Cash TP, Yoon SS, Skuli N, Park KM, Gerecht S, Simon MC.

Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):E3402-11. doi: 10.1073/pnas.1420005112. Epub 2015 Jun 15.

43.

Fabrication of 3-dimensional multicellular microvascular structures.

Barreto-Ortiz SF, Fradkin J, Eoh J, Trivero J, Davenport M, Ginn B, Mao HQ, Gerecht S.

FASEB J. 2015 Aug;29(8):3302-14. doi: 10.1096/fj.14-263343. Epub 2015 Apr 21.

44.

Acellular implantable and injectable hydrogels for vascular regeneration.

Blatchley MR, Gerecht S.

Biomed Mater. 2015 Mar 16;10(3):034001. doi: 10.1088/1748-6041/10/3/034001. Review.

PMID:
25775039
45.

Micropattern size-dependent endothelial differentiation from a human induced pluripotent stem cell line.

Kusuma S, Smith Q, Facklam A, Gerecht S.

J Tissue Eng Regen Med. 2017 Mar;11(3):855-861. doi: 10.1002/term.1985. Epub 2015 Jan 30.

46.

Capillary Network-Like Organization of Endothelial Cells in PEGDA Scaffolds Encoded with Angiogenic Signals via Triple Helical Hybridization.

Stahl PJ, Chan TR, Shen YI, Sun G, Gerecht S, Yu SM.

Adv Funct Mater. 2014 Jun 4;24(21):3213-3225. No abstract available.

47.

Derivation of Endothelial Cells and Pericytes from Human Pluripotent Stem Cells.

Kusuma S, Gerecht S.

Methods Mol Biol. 2016;1307:213-22. doi: 10.1007/7651_2014_149.

PMID:
25515528
48.

The design of dextran-based hypoxia-inducible hydrogels via in situ oxygen-consuming reaction.

Park KM, Blatchley MR, Gerecht S.

Macromol Rapid Commun. 2014 Nov;35(22):1968-75. doi: 10.1002/marc.201400369. Epub 2014 Oct 9.

49.

Hypoxia and free radicals: role in tumor progression and the use of engineering-based platforms to address these relationships.

Hielscher A, Gerecht S.

Free Radic Biol Med. 2015 Feb;79:281-91. doi: 10.1016/j.freeradbiomed.2014.09.015. Epub 2014 Oct 22. Review.

50.

Characterizing human pluripotent-stem-cell-derived vascular cells for tissue engineering applications.

Kusuma S, Facklam A, Gerecht S.

Stem Cells Dev. 2015 Feb 15;24(4):451-8. doi: 10.1089/scd.2014.0377. Epub 2014 Oct 27.

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