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Items: 1 to 50 of 151

1.

Identification of new transmembrane proteins concentrated at the nuclear envelope using organellar proteomics of mesenchymal cells.

Cheng LC, Baboo S, Lindsay C, Brusman L, Martinez-Bartolomé S, Tapia O, Zhang X, Yates JR 3rd, Gerace L.

Nucleus. 2019 Dec;10(1):126-143. doi: 10.1080/19491034.2019.1618175.

2.

Messages from the voices within: regulation of signaling by proteins of the nuclear lamina.

Gerace L, Tapia O.

Curr Opin Cell Biol. 2018 Jun;52:14-21. doi: 10.1016/j.ceb.2017.12.009. Epub 2018 Jan 4. Review.

3.

Luma is not essential for murine cardiac development and function.

Stroud MJ, Fang X, Zhang J, Guimarães-Camboa N, Veevers J, Dalton ND, Gu Y, Bradford WH, Peterson KL, Evans SM, Gerace L, Chen J.

Cardiovasc Res. 2018 Mar 1;114(3):378-388. doi: 10.1093/cvr/cvx205.

4.

A Survey of DDX21 Activity During Rev/RRE Complex Formation.

Hammond JA, Zhou L, Lamichhane R, Chu HY, Millar DP, Gerace L, Williamson JR.

J Mol Biol. 2018 Feb 16;430(4):537-553. doi: 10.1016/j.jmb.2017.06.023. Epub 2017 Jul 10.

5.

Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle.

Stroud MJ, Feng W, Zhang J, Veevers J, Fang X, Gerace L, Chen J.

J Cell Biol. 2017 Jul 3;216(7):1915-1924. doi: 10.1083/jcb.201612128. Epub 2017 May 22.

6.

Analysis of Nuclear Lamina Proteins in Myoblast Differentiation by Functional Complementation.

Tapia O, Gerace L.

Methods Mol Biol. 2016;1411:177-94. doi: 10.1007/978-1-4939-3530-7_11.

7.

Nuclear envelope protein Lem2 is required for mouse development and regulates MAP and AKT kinases.

Tapia O, Fong LG, Huber MD, Young SG, Gerace L.

PLoS One. 2015 Mar 19;10(3):e0116196. doi: 10.1371/journal.pone.0116196. eCollection 2015.

8.

Nuclear import of adenovirus DNA involves direct interaction of hexon with an N-terminal domain of the nucleoporin Nup214.

Cassany A, Ragues J, Guan T, Bégu D, Wodrich H, Kann M, Nemerow GR, Gerace L.

J Virol. 2015 Feb;89(3):1719-30. doi: 10.1128/JVI.02639-14. Epub 2014 Nov 19.

9.

Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.

Banerjee I, Zhang J, Moore-Morris T, Pfeiffer E, Buchholz KS, Liu A, Ouyang K, Stroud MJ, Gerace L, Evans SM, McCulloch A, Chen J.

PLoS Genet. 2014 Feb 20;10(2):e1004114. doi: 10.1371/journal.pgen.1004114. eCollection 2014 Feb.

10.

Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis.

Huber MD, Vesely PW, Datta K, Gerace L.

J Cell Biol. 2013 Nov 11;203(3):427-36. doi: 10.1083/jcb.201305076.

11.

Caregivers' beliefs associated with medication adherence among children and adolescents with epilepsy.

Miner PJ, Alexander J, Ewing H, Gerace L.

J Neurosci Nurs. 2013 Aug;45(4):211-8. doi: 10.1097/JNN.0b013e3182986127.

PMID:
23812051
12.

Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production.

Naji S, Ambrus G, Cimermančič P, Reyes JR, Johnson JR, Filbrandt R, Huber MD, Vesely P, Krogan NJ, Yates JR 3rd, Saphire AC, Gerace L.

Mol Cell Proteomics. 2012 Apr;11(4):M111.015313. doi: 10.1074/mcp.M111.015313. Epub 2011 Dec 15.

13.

Nuclear lamina at the crossroads of the cytoplasm and nucleus.

Gerace L, Huber MD.

J Struct Biol. 2012 Jan;177(1):24-31. doi: 10.1016/j.jsb.2011.11.007. Epub 2011 Nov 22. Review.

14.

The structure of the NXF2/NXT1 heterodimeric complex reveals the combined specificity and versatility of the NTF2-like fold.

Kerkow DE, Carmel AB, Menichelli E, Ambrus G, Hills RD Jr, Gerace L, Williamson JR.

J Mol Biol. 2012 Jan 27;415(4):649-65. doi: 10.1016/j.jmb.2011.11.027. Epub 2011 Nov 22.

15.

DDX1 is an RNA-dependent ATPase involved in HIV-1 Rev function and virus replication.

Edgcomb SP, Carmel AB, Naji S, Ambrus-Aikelin G, Reyes JR, Saphire AC, Gerace L, Williamson JR.

J Mol Biol. 2012 Jan 6;415(1):61-74. doi: 10.1016/j.jmb.2011.10.032. Epub 2011 Oct 25.

16.

Small molecule peptidomimetic inhibitors of importin α/β mediated nuclear transport.

Ambrus G, Whitby LR, Singer EL, Trott O, Choi E, Olson AJ, Boger DL, Gerace L.

Bioorg Med Chem. 2010 Nov 1;18(21):7611-20. doi: 10.1016/j.bmc.2010.08.038. Epub 2010 Aug 21.

17.

Identification of a small molecule inhibitor of importin β mediated nuclear import by confocal on-bead screening of tagged one-bead one-compound libraries.

Hintersteiner M, Ambrus G, Bednenko J, Schmied M, Knox AJ, Meisner NC, Gstach H, Seifert JM, Singer EL, Gerace L, Auer M.

ACS Chem Biol. 2010 Oct 15;5(10):967-79. doi: 10.1021/cb100094k.

18.

Karyopherin binding interactions and nuclear import mechanism of nuclear pore complex protein Tpr.

Ben-Efraim I, Frosst PD, Gerace L.

BMC Cell Biol. 2009 Oct 16;10:74. doi: 10.1186/1471-2121-10-74.

19.

Repression of classical nuclear export by S-nitrosylation of CRM1.

Wang P, Liu GH, Wu K, Qu J, Huang B, Zhang X, Zhou X, Gerace L, Chen C.

J Cell Sci. 2009 Oct 15;122(Pt 20):3772-9. doi: 10.1242/jcs.057026.

20.

Sumoylation regulates nuclear localization of lipin-1alpha in neuronal cells.

Liu GH, Gerace L.

PLoS One. 2009 Sep 15;4(9):e7031. doi: 10.1371/journal.pone.0007031.

21.
22.

Reduction of a 4q35-encoded nuclear envelope protein in muscle differentiation.

Ostlund C, Guan T, Figlewicz DA, Hays AP, Worman HJ, Gerace L, Schirmer EC.

Biochem Biophys Res Commun. 2009 Nov 13;389(2):279-83. doi: 10.1016/j.bbrc.2009.08.133. Epub 2009 Aug 28.

23.

NET37, a nuclear envelope transmembrane protein with glycosidase homology, is involved in myoblast differentiation.

Datta K, Guan T, Gerace L.

J Biol Chem. 2009 Oct 23;284(43):29666-76. doi: 10.1074/jbc.M109.034041. Epub 2009 Aug 25.

24.

Regulation of myoblast differentiation by the nuclear envelope protein NET39.

Liu GH, Guan T, Datta K, Coppinger J, Yates J 3rd, Gerace L.

Mol Cell Biol. 2009 Nov;29(21):5800-12. doi: 10.1128/MCB.00684-09. Epub 2009 Aug 24.

25.

Reconstitution of nuclear import in permeabilized cells.

Cassany A, Gerace L.

Methods Mol Biol. 2009;464:181-205. doi: 10.1007/978-1-60327-461-6_11.

26.

Neutralizing antibody blocks adenovirus infection by arresting microtubule-dependent cytoplasmic transport.

Smith JG, Cassany A, Gerace L, Ralston R, Nemerow GR.

J Virol. 2008 Jul;82(13):6492-500. doi: 10.1128/JVI.00557-08. Epub 2008 Apr 30.

27.

Protein structure and oligomerization are important for the formation of export-competent HIV-1 Rev-RRE complexes.

Edgcomb SP, Aschrafi A, Kompfner E, Williamson JR, Gerace L, Hennig M.

Protein Sci. 2008 Mar;17(3):420-30. doi: 10.1110/ps.073246608. Epub 2008 Jan 24.

28.

The size-wise nucleus: nuclear volume control in eukaryotes.

Huber MD, Gerace L.

J Cell Biol. 2007 Nov 19;179(4):583-4. Epub 2007 Nov 12.

29.

Nuclear envelope transmembrane proteins (NETs) that are up-regulated during myogenesis.

Chen IH, Huber M, Guan T, Bubeck A, Gerace L.

BMC Cell Biol. 2006 Oct 24;7:38.

30.

Adenovirus core protein pVII is translocated into the nucleus by multiple import receptor pathways.

Wodrich H, Cassany A, D'Angelo MA, Guan T, Nemerow G, Gerace L.

J Virol. 2006 Oct;80(19):9608-18.

31.

The nuclear membrane proteome: extending the envelope.

Schirmer EC, Gerace L.

Trends Biochem Sci. 2005 Oct;30(10):551-8. Review.

32.

Cross-talk between snurportin1 subdomains.

Ospina JK, Gonsalvez GB, Bednenko J, Darzynkiewicz E, Gerace L, Matera AG.

Mol Biol Cell. 2005 Oct;16(10):4660-71. Epub 2005 Jul 19.

33.

Mutation analysis of the HFE gene associated with hereditary hemochromatosis in a Venezuelan sample.

Vizzi E, Loureiro CL, Gerder M, de las Nieves Garcia-Casal M, Rodríguez-Larralde A, Gerace L, Ludert JE, Liprandi F, Pujol FH.

Ann Hematol. 2005 Nov;84(12):802-6. Epub 2005 Nov 12.

PMID:
15995871
34.

Identification of novel integral membrane proteins of the nuclear envelope with potential disease links using subtractive proteomics.

Schirmer EC, Florens L, Guan T, Yates JR 3rd, Gerace L.

Novartis Found Symp. 2005;264:63-76; discussion 76-80, 227-30. Review.

PMID:
15773748
35.

Adenovirus protein VI mediates membrane disruption following capsid disassembly.

Wiethoff CM, Wodrich H, Gerace L, Nemerow GR.

J Virol. 2005 Feb;79(4):1992-2000.

36.

Energy- and temperature-dependent transport of integral proteins to the inner nuclear membrane via the nuclear pore.

Ohba T, Schirmer EC, Nishimoto T, Gerace L.

J Cell Biol. 2004 Dec 20;167(6):1051-62.

37.

The clinical significance of the POLG gene polymorphism in male infertility.

Krausz C, Guarducci E, Becherini L, Degl'Innocenti S, Gerace L, Balercia G, Forti G.

J Clin Endocrinol Metab. 2004 Sep;89(9):4292-7.

PMID:
15356024
38.
39.

TorsinA and torsion dystonia: Unraveling the architecture of the nuclear envelope.

Gerace L.

Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):8839-40. Epub 2004 Jun 8. Review. No abstract available.

40.

Phospholipid scramblase 1 is imported into the nucleus by a receptor-mediated pathway and interacts with DNA.

Ben-Efraim I, Zhou Q, Wiedmer T, Gerace L, Sims PJ.

Biochemistry. 2004 Mar 30;43(12):3518-26.

PMID:
15035622
41.

Switch from capsid protein import to adenovirus assembly by cleavage of nuclear transport signals.

Wodrich H, Guan T, Cingolani G, Von Seggern D, Nemerow G, Gerace L.

EMBO J. 2003 Dec 1;22(23):6245-55.

42.

MudPIT: A powerful proteomics tool for discovery.

Schirmer EC, Yates JR 3rd, Gerace L.

Discov Med. 2003 Oct;3(18):38-9.

43.

Nuclear membrane proteins with potential disease links found by subtractive proteomics.

Schirmer EC, Florens L, Guan T, Yates JR 3rd, Gerace L.

Science. 2003 Sep 5;301(5638):1380-2.

44.

Importin beta contains a COOH-terminal nucleoporin binding region important for nuclear transport.

Bednenko J, Cingolani G, Gerace L.

J Cell Biol. 2003 Aug 4;162(3):391-401. Epub 2003 Jul 28.

45.

Nucleocytoplasmic transport: navigating the channel.

Bednenko J, Cingolani G, Gerace L.

Traffic. 2003 Mar;4(3):127-35. Review.

46.

Synergy of silent and hot spot mutations in importin beta reveals a dynamic mechanism for recognition of a nuclear localization signal.

Koerner C, Guan T, Gerace L, Cingolani G.

J Biol Chem. 2003 May 2;278(18):16216-21. Epub 2003 Feb 19.

47.

Molecular basis for the recognition of a nonclassical nuclear localization signal by importin beta.

Cingolani G, Bednenko J, Gillespie MT, Gerace L.

Mol Cell. 2002 Dec;10(6):1345-53.

48.

Influence of cargo size on Ran and energy requirements for nuclear protein import.

Lyman SK, Guan T, Bednenko J, Wodrich H, Gerace L.

J Cell Biol. 2002 Oct 14;159(1):55-67. Epub 2002 Oct 7.

49.

Analysis of nuclear protein import and export in vitro using fluorescent cargoes.

Kehlenbach RH, Gerace L.

Methods Mol Biol. 2002;189:231-45. No abstract available.

PMID:
12094590
50.

Genetic differentiation within and between populations of a hermaphroditic freshwater planarian.

Pongratz N, Gerace L, Michiels NK.

Heredity (Edinb). 2002 Jul;89(1):64-9.

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