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Items: 7


Modeling blood diseases with human induced pluripotent stem cells.

Georgomanoli M, Papapetrou EP.

Dis Model Mech. 2019 Jun 4;12(6). pii: dmm039321. doi: 10.1242/dmm.039321. Review.


A Novel BaEVRless-Pseudotyped γ-Globin Lentiviral Vector Drives High and Stable Fetal Hemoglobin Expression and Improves Thalassemic Erythropoiesis In Vitro.

Drakopoulou E, Georgomanoli M, Lederer CW, Kleanthous M, Costa C, Bernadin O, Cosset FL, Voskaridou E, Verhoeyen E, Papanikolaou E, Anagnou NP.

Hum Gene Ther. 2019 May;30(5):601-617. doi: 10.1089/hum.2018.022. Epub 2019 Mar 15.


Dissecting the Contributions of Cooperating Gene Mutations to Cancer Phenotypes and Drug Responses with Patient-Derived iPSCs.

Chang CJ, Kotini AG, Olszewska M, Georgomanoli M, Teruya-Feldstein J, Sperber H, Sanchez R, DeVita R, Martins TJ, Abdel-Wahab O, Bradley RK, Papapetrou EP.

Stem Cell Reports. 2018 May 8;10(5):1610-1624. doi: 10.1016/j.stemcr.2018.03.020. Epub 2018 Apr 19.


Towards more successful gene therapy clinical trials for β-thalassemia.

Drakopoulou E, Papanikolaou E, Georgomanoli M, Anagnou NP.

Curr Mol Med. 2013 Sep;13(8):1314-30. Review.


Characterization and comparative performance of lentiviral vector preparations concentrated by either one-step ultrafiltration or ultracentrifugation.

Papanikolaou E, Kontostathi G, Drakopoulou E, Georgomanoli M, Stamateris E, Vougas K, Vlahou A, Maloy A, Ware M, Anagnou NP.

Virus Res. 2013 Jul;175(1):1-11. doi: 10.1016/j.virusres.2013.03.015. Epub 2013 Apr 11.


The new self-inactivating lentiviral vector for thalassemia gene therapy combining two HPFH activating elements corrects human thalassemic hematopoietic stem cells.

Papanikolaou E, Georgomanoli M, Stamateris E, Panetsos F, Karagiorga M, Tsaftaridis P, Graphakos S, Anagnou NP.

Hum Gene Ther. 2012 Jan;23(1):15-31. doi: 10.1089/hum.2011.048. Epub 2011 Dec 5.


Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer.

Wilber A, Hargrove PW, Kim YS, Riberdy JM, Sankaran VG, Papanikolaou E, Georgomanoli M, Anagnou NP, Orkin SH, Nienhuis AW, Persons DA.

Blood. 2011 Mar 10;117(10):2817-26. doi: 10.1182/blood-2010-08-300723. Epub 2010 Dec 14.

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