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Items: 1 to 50 of 203


The Bio-inspired Artificial Pancreas for Type 1 Diabetes Control in the Home: System Architecture and Preliminary Results.

Herrero P, El-Sharkawy M, Daniels J, Jugnee N, Uduku CN, Reddy M, Oliver N, Georgiou P.

J Diabetes Sci Technol. 2019 Oct 14:1932296819881456. doi: 10.1177/1932296819881456. [Epub ahead of print]


Long-Term Glucose Forecasting Using a Physiological Model and Deconvolution of the Continuous Glucose Monitoring Signal.

Liu C, Vehí J, Avari P, Reddy M, Oliver N, Georgiou P, Herrero P.

Sensors (Basel). 2019 Oct 8;19(19). pii: E4338. doi: 10.3390/s19194338.


Quantitative and rapid Plasmodium falciparum malaria diagnosis and artemisinin-resistance detection using a CMOS Lab-on-Chip platform.

Malpartida-Cardenas K, Miscourides N, Rodriguez-Manzano J, Yu LS, Moser N, Baum J, Georgiou P.

Biosens Bioelectron. 2019 Sep 7;145:111678. doi: 10.1016/j.bios.2019.111678. [Epub ahead of print]


Predicting Quality of Overnight Glycaemic Control in Type 1 Diabetes using Binary Classifiers.

Guemes A, Cappon G, Hernandez B, Reddy M, Oliver N, Georgiou P, Herrero P.

IEEE J Biomed Health Inform. 2019 Sep 13. doi: 10.1109/JBHI.2019.2938305. [Epub ahead of print]


Classical conditioning of antidepressant placebo effects in mice.

Krimmel SR, Zanos P, Georgiou P, Colloca L, Gould TD.

Psychopharmacology (Berl). 2019 Aug 17. doi: 10.1007/s00213-019-05347-4. [Epub ahead of print]


GluNet: A Deep Learning Framework For Accurate Glucose Forecasting.

Li K, Liu C, Zhu T, Herrero P, Georgiou P.

IEEE J Biomed Health Inform. 2019 Jul 29. doi: 10.1109/JBHI.2019.2931842. [Epub ahead of print]


Classification of Postprandial Glycemic Status with Application to Insulin Dosing in Type 1 Diabetes-An In Silico Proof-of-Concept.

Cappon G, Facchinetti A, Sparacino G, Georgiou P, Herrero P.

Sensors (Basel). 2019 Jul 18;19(14). pii: E3168. doi: 10.3390/s19143168.


Tuning the membrane permeability of polymersome nanoreactors developed by aqueous emulsion polymerization-induced self-assembly.

Varlas S, Foster JC, Georgiou PG, Keogh R, Husband JT, Williams DS, O'Reilly RK.

Nanoscale. 2019 Jul 14;11(26):12643-12654. doi: 10.1039/c9nr02507c. Epub 2019 Jun 25.


Artificial intelligence can improve decision-making in infection management.

Rawson TM, Ahmad R, Toumazou C, Georgiou P, Holmes AH.

Nat Hum Behav. 2019 Jun;3(6):543-545. doi: 10.1038/s41562-019-0583-9. No abstract available.


Tumor Angiogenesis Is Differentially Regulated by Phosphorylation of Endothelial Cell Focal Adhesion Kinase Tyrosines-397 and -861.

Pedrosa AR, Bodrug N, Gomez-Escudero J, Carter EP, Reynolds LE, Georgiou PN, Fernandez I, Lees DM, Kostourou V, Alexopoulou AN, Batista S, Tavora B, Serrels B, Parsons M, Iskratsch T, Hodivala-Dilke KM.

Cancer Res. 2019 Sep 1;79(17):4371-4386. doi: 10.1158/0008-5472.CAN-18-3934. Epub 2019 Jun 12.


A Modular Safety System for an Insulin Dose Recommender: A Feasibility Study.

Liu C, Avari P, Leal Y, Wos M, Sivasithamparam K, Georgiou P, Reddy M, Fernández-Real JM, Martin C, Fernández-Balsells M, Oliver N, Herrero P.

J Diabetes Sci Technol. 2019 May 22:1932296819851135. doi: 10.1177/1932296819851135. [Epub ahead of print]


Framework for DNA Quantification and Outlier Detection Using Multidimensional Standard Curves.

Moniri A, Rodriguez-Manzano J, Malpartida-Cardenas K, Yu LS, Didelot X, Holmes A, Georgiou P.

Anal Chem. 2019 Jun 4;91(11):7426-7434. doi: 10.1021/acs.analchem.9b01466. Epub 2019 May 14.


Connectivity of rapid-testing diagnostics and surveillance of infectious diseases.

Ming D, Rawson T, Sangkaew S, Rodriguez-Manzano J, Georgiou P, Holmes A.

Bull World Health Organ. 2019 Mar 1;97(3):242-244. doi: 10.2471/BLT.18.219691. Epub 2019 Feb 4. No abstract available.


Design feasibility of an automated, machine-learning based feedback system for motivational interviewing.

Imel ZE, Pace BT, Soma CS, Tanana M, Hirsch T, Gibson J, Georgiou P, Narayanan S, Atkins DC.

Psychotherapy (Chic). 2019 Jun;56(2):318-328. doi: 10.1037/pst0000221. Epub 2019 Apr 8.


Convolutional Recurrent Neural Networks for Glucose Prediction.

Li K, Daniels J, Liu C, Herrero-Vinas P, Georgiou P.

IEEE J Biomed Health Inform. 2019 Apr 1. doi: 10.1109/JBHI.2019.2908488. [Epub ahead of print]


Subchondral Cyst-Like Lesion of the Hand in a Patient With Rheumatoid Arthritis.

Ntelis K, Melissaropoulos K, Georgiou P.

J Clin Rheumatol. 2019 Apr 3. doi: 10.1097/RHU.0000000000001033. [Epub ahead of print] No abstract available.


(R)-Ketamine exerts antidepressant actions partly via conversion to (2R,6R)-hydroxynorketamine, while causing adverse effects at sub-anaesthetic doses.

Zanos P, Highland JN, Liu X, Troppoli TA, Georgiou P, Lovett J, Morris PJ, Stewart BW, Thomas CJ, Thompson SM, Moaddel R, Gould TD.

Br J Pharmacol. 2019 Jul;176(14):2573-2592. doi: 10.1111/bph.14683. Epub 2019 May 13.


Group II metabotropic glutamate receptor blockade promotes stress resilience in mice.

Highland JN, Zanos P, Georgiou P, Gould TD.

Neuropsychopharmacology. 2019 Sep;44(10):1788-1796. doi: 10.1038/s41386-019-0380-1. Epub 2019 Apr 2.


(2R,6R)-hydroxynorketamine exerts mGlu2 receptor-dependent antidepressant actions.

Zanos P, Highland JN, Stewart BW, Georgiou P, Jenne CE, Lovett J, Morris PJ, Thomas CJ, Moaddel R, Zarate CA Jr, Gould TD.

Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6441-6450. doi: 10.1073/pnas.1819540116. Epub 2019 Mar 13.


Sex-Specific Involvement of Estrogen Receptors in Behavioral Responses to Stress and Psychomotor Activation.

Georgiou P, Zanos P, Jenne CE, Gould TD.

Front Psychiatry. 2019 Feb 26;10:81. doi: 10.3389/fpsyt.2019.00081. eCollection 2019.


Modeling the effect of the cephalic phase of insulin secretion on glucose metabolism.

Güemes A, Herrero P, Bondia J, Georgiou P.

Med Biol Eng Comput. 2019 Jun;57(6):1173-1186. doi: 10.1007/s11517-019-01950-x. Epub 2019 Jan 26.


Simultaneous Single-Channel Multiplexing and Quantification of Carbapenem-Resistant Genes Using Multidimensional Standard Curves.

Rodriguez-Manzano J, Moniri A, Malpartida-Cardenas K, Dronavalli J, Davies F, Holmes A, Georgiou P.

Anal Chem. 2019 Feb 5;91(3):2013-2020. doi: 10.1021/acs.analchem.8b04412. Epub 2019 Jan 24.


Supervised machine learning for the prediction of infection on admission to hospital: a prospective observational cohort study.

Rawson TM, Hernandez B, Moore LSP, Blandy O, Herrero P, Gilchrist M, Gordon A, Toumazou C, Sriskandan S, Georgiou P, Holmes AH.

J Antimicrob Chemother. 2019 Apr 1;74(4):1108-1115. doi: 10.1093/jac/dky514.


Rapid and Sensitive Detection of Azole-Resistant Aspergillus fumigatus by Tandem Repeat Loop-Mediated Isothermal Amplification.

Yu LS, Rodriguez-Manzano J, Malpartida-Cardenas K, Sewell T, Bader O, Armstrong-James D, Fisher MC, Georgiou P.

J Mol Diagn. 2019 Mar;21(2):286-295. doi: 10.1016/j.jmoldx.2018.10.004. Epub 2018 Dec 4.


Triple combination of meropenem, colistin and tigecycline was bactericidal in a dynamic model despite mere additive interactions in chequerboard assays against carbapenemase-producing Klebsiella pneumoniae isolates.

Tsala M, Vourli S, Georgiou PC, Pournaras S, Daikos GRL, Mouton JW, Meletiadis J.

J Antimicrob Chemother. 2019 Feb 1;74(2):387-394. doi: 10.1093/jac/dky422.


Poly(sarcosine)-Based Nano-Objects with Multi-Protease Resistance by Aqueous Photoinitiated Polymerization-Induced Self-Assembly (Photo-PISA).

Varlas S, Georgiou PG, Bilalis P, Jones JR, Hadjichristidis N, O'Reilly RK.

Biomacromolecules. 2018 Nov 12;19(11):4453-4462. doi: 10.1021/acs.biomac.8b01326. Epub 2018 Nov 1.


Allele-Specific Isothermal Amplification Method Using Unmodified Self-Stabilizing Competitive Primers.

Malpartida-Cardenas K, Rodriguez-Manzano J, Yu LS, Delves MJ, Nguon C, Chotivanich K, Baum J, Georgiou P.

Anal Chem. 2018 Oct 16;90(20):11972-11980. doi: 10.1021/acs.analchem.8b02416. Epub 2018 Oct 2.


Chronic nicotine administration restores brain region specific upregulation of oxytocin receptor binding levels in a G72 mouse model of schizophrenia.

Zanos P, Keyworth H, Georgiou P, Hambsch B, Otte DM, Kitchen I, Zimmer A, Bailey A.

Eur J Neurosci. 2019 Aug;50(3):2255-2263. doi: 10.1111/ejn.14155. Epub 2018 Oct 10.


Clinical and immunological parameters of Sjögren's syndrome.

Psianou K, Panagoulias I, Papanastasiou AD, de Lastic AL, Rodi M, Spantidea PI, Degn SE, Georgiou P, Mouzaki A.

Autoimmun Rev. 2018 Oct;17(10):1053-1064. doi: 10.1016/j.autrev.2018.05.005. Epub 2018 Aug 10. Review.


Public acceptability of computer-controlled antibiotic management: An exploration of automated dosing and opportunities for implementation.

Rawson TM, Ming D, Gowers SA, Freeman DM, Herrero P, Georgiou P, Cass AE, O'Hare D, Holmes AH.

J Infect. 2019 Jan;78(1):75-86. doi: 10.1016/j.jinf.2018.08.005. Epub 2018 Aug 10.


Poly(Pentafluorophenyl Methacrylate)-Based Nano-Objects Developed by Photo-PISA as Scaffolds for Post-Polymerization Functionalization.

Couturaud B, Georgiou PG, Varlas S, Jones JR, Arno MC, Foster JC, O'Reilly RK.

Macromol Rapid Commun. 2019 Jan;40(2):e1800460. doi: 10.1002/marc.201800460. Epub 2018 Jul 30.


A 12.8 k Current-Mode Velocity-Saturation ISFET Array for On-Chip Real-Time DNA Detection.

Miscourides N, Yu LS, Rodriguez-Manzano J, Georgiou P.

IEEE Trans Biomed Circuits Syst. 2018 Oct;12(5):1202-1214. doi: 10.1109/TBCAS.2018.2851448. Epub 2018 Jul 16.


Adapting ISFETs for Epigenetics: An Overview.

Ma D, Rodriguez-Manzano J, de Mateo Lopez S, Kalofonou M, Georgiou P, Toumazou C.

IEEE Trans Biomed Circuits Syst. 2018 Oct;12(5):1186-1201. doi: 10.1109/TBCAS.2018.2838153. Epub 2018 Jul 13.


Closed-Loop Control for Precision Antimicrobial Delivery: An In Silico Proof-of-Concept.

Herrero P, Rawson TM, Philip A, Moore LSP, Holmes AH, Georgiou P.

IEEE Trans Biomed Eng. 2018 Oct;65(10):2231-2236. doi: 10.1109/TBME.2017.2787423. Epub 2017 Dec 25.


7B2 chaperone knockout in APP model mice results in reduced plaque burden.

Jarvela TS, Womack T, Georgiou P, Gould TD, Eriksen JL, Lindberg I.

Sci Rep. 2018 Jun 28;8(1):9813. doi: 10.1038/s41598-018-28031-7.


Correction to: Improving Dengue Diagnostics and Management Through Innovative Technology.

Rodriguez-Manzano J, Chia PY, Yeo TW, Holmes A, Georgiou P, Yacoub S.

Curr Infect Dis Rep. 2018 Jun 27;20(8):28. doi: 10.1007/s11908-018-0646-5.


Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms.

Zanos P, Moaddel R, Morris PJ, Riggs LM, Highland JN, Georgiou P, Pereira EFR, Albuquerque EX, Thomas CJ, Zarate CA Jr, Gould TD.

Pharmacol Rev. 2018 Jul;70(3):621-660. doi: 10.1124/pr.117.015198. Review. Erratum in: Pharmacol Rev. 2018 Oct;70(4):879.


Environmental enrichment enhances conditioned place preference to ethanol via an oxytocinergic-dependent mechanism in male mice.

Rae M, Zanos P, Georgiou P, Chivers P, Bailey A, Camarini R.

Neuropharmacology. 2018 Aug;138:267-274. doi: 10.1016/j.neuropharm.2018.06.013. Epub 2018 Jun 21.


Improving Dengue Diagnostics and Management Through Innovative Technology.

Rodriguez-Manzano J, Chia PY, Yeo TW, Holmes A, Georgiou P, Yacoub S.

Curr Infect Dis Rep. 2018 Jun 7;20(8):25. doi: 10.1007/s11908-018-0633-x. Review. Erratum in: Curr Infect Dis Rep. 2018 Jun 27;20(8):28.


Inhibition of alpha7 nicotinic receptors in the ventral hippocampus selectively attenuates reinstatement of morphine-conditioned place preference and associated changes in AMPA receptor binding.

Wright VL, Georgiou P, Bailey A, Heal DJ, Bailey CP, Wonnacott S.

Addict Biol. 2019 Jul;24(4):590-603. doi: 10.1111/adb.12624. Epub 2018 Apr 17.


Cardiovascular Reactivity During Marital Conflict in Laboratory and Naturalistic Settings: Differential Associations with Relationship and Individual Functioning Across Contexts.

Baucom BRW, Baucom KJW, Hogan JN, Crenshaw AO, Bourne SV, Crowell SE, Georgiou P, Goodwin MS.

Fam Process. 2018 Sep;57(3):662-678. doi: 10.1111/famp.12353. Epub 2018 Mar 25.


A Scalable ISFET Sensing and Memory Array With Sensor Auto-Calibration for On-Chip Real-Time DNA Detection.

Moser N, Rodriguez-Manzano J, Lande TS, Georgiou P.

IEEE Trans Biomed Circuits Syst. 2018 Apr;12(2):390-401. doi: 10.1109/TBCAS.2017.2789161.


Vital Sign Monitoring Through the Back Using an UWB Impulse Radar With Body Coupled Antennas.

Schires E, Georgiou P, Lande TS.

IEEE Trans Biomed Circuits Syst. 2018 Apr;12(2):292-302. doi: 10.1109/TBCAS.2018.2799322.


Development of a patient-centred intervention to improve knowledge and understanding of antibiotic therapy in secondary care.

Rawson TM, Moore LSP, Castro-Sanchez E, Charani E, Hernandez B, Alividza V, Husson F, Toumazou C, Ahmad R, Georgiou P, Holmes AH.

Antimicrob Resist Infect Control. 2018 Mar 20;7:43. doi: 10.1186/s13756-018-0333-1. eCollection 2018.


Exploring the Use of C-Reactive Protein to Estimate the Pharmacodynamics of Vancomycin.

Rawson TM, Charani E, Moore LSP, Gilchrist M, Georgiou P, Hope W, Holmes AH.

Ther Drug Monit. 2018 Jun;40(3):315-321. doi: 10.1097/FTD.0000000000000507.


Automatic Adaptation of Basal Insulin Using Sensor-Augmented Pump Therapy.

Herrero P, Bondia J, Giménez M, Oliver N, Georgiou P.

J Diabetes Sci Technol. 2018 Mar;12(2):282-294. doi: 10.1177/1932296818761752.


Glutamatergic Ventral Pallidal Neurons Modulate Activity of the Habenula-Tegmental Circuitry and Constrain Reward Seeking.

Tooley J, Marconi L, Alipio JB, Matikainen-Ankney B, Georgiou P, Kravitz AV, Creed MC.

Biol Psychiatry. 2018 Jun 15;83(12):1012-1023. doi: 10.1016/j.biopsych.2018.01.003. Epub 2018 Jan 12.


Association between spectral characteristics of paraspinal muscles and functional disability in patients with low back pain: a cohort study.

Chiou SY, Koutsos E, Georgiou P, Strutton PH.

BMJ Open. 2018 Feb 14;8(2):e017091. doi: 10.1136/bmjopen-2017-017091.


Methamphetamine withdrawal induces activation of CRF neurons in the brain stress system in parallel with an increased activity of cardiac sympathetic pathways.

García-Carmona JA, Georgiou P, Zanos P, Bailey A, Laorden ML.

Naunyn Schmiedebergs Arch Pharmacol. 2018 Apr;391(4):423-434. doi: 10.1007/s00210-018-1470-z. Epub 2018 Jan 30.


Exploring colistin pharmacodynamics against Klebsiella pneumoniae: a need to revise current susceptibility breakpoints.

Tsala M, Vourli S, Georgiou PC, Pournaras S, Tsakris A, Daikos GL, Mouton JW, Meletiadis J.

J Antimicrob Chemother. 2018 Apr 1;73(4):953-961. doi: 10.1093/jac/dkx522.


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