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Items: 1 to 50 of 148


The Hordeum bulbosum 25S-18S rDNA region: comparison with Hordeum vulgare and other Triticeae.

Georgiev O, Mishev K, Krasnikova M, Kitanova M, Dimitrova A, Karagyozov L.

Z Naturforsch C. 2019 Aug 17. pii: /j/znc.ahead-of-print/znc-2018-0109/znc-2018-0109.xml. doi: 10.1515/znc-2018-0109. [Epub ahead of print]


Chronic obstructive pulmonary disease exacerbations and progression in relation to ambient air pollutants exposure.

Doneva M, Petrova G, Petrova D, Kamusheva M, Petkova V, Tachkov K, Pencheva V, Georgiev O.

J Thorac Dis. 2019 Jun;11(6):2490-2497. doi: 10.21037/jtd.2019.05.50.


Cognitive Impairment and Affective Disorders in Patients With Obstructive Sleep Apnea Syndrome.

Bilyukov RG, Nikolov MS, Pencheva VP, Petrova DS, Georgiev OB, Mondeshki TL, Milanova VK.

Front Psychiatry. 2018 Aug 7;9:357. doi: 10.3389/fpsyt.2018.00357. eCollection 2018.


Pericardial Effusion in Obstructive Sleep Apnea without Pulmonary Arterial Hypertension and Daily Hypoxemia - is it Unusual?

Manov EI, Pencheva VP, Runev NM, Naydenov SN, Petrova DS, Georgiev OB.

Balkan Med J. 2018 May 29;35(3):233-237. doi: 10.4274/balkanmedj.2017.0580.


Rhinovirus 3C protease suppresses apoptosis and triggers caspase-independent cell death.

Lötzerich M, Roulin PS, Boucke K, Witte R, Georgiev O, Greber UF.

Cell Death Dis. 2018 Feb 15;9(3):272. doi: 10.1038/s41419-018-0306-6.


Dysbindin links presynaptic proteasome function to homeostatic recruitment of low release probability vesicles.

Wentzel C, Delvendahl I, Sydlik S, Georgiev O, Müller M.

Nat Commun. 2018 Jan 18;9(1):267. doi: 10.1038/s41467-017-02494-0.


Assessment of the expectancy, seriousness and severity of adverse drug reactions reported for chronic obstructive pulmonary disease therapy.

Petrova G, Stoimenova A, Dimitrova M, Kamusheva M, Petrova D, Georgiev O.

SAGE Open Med. 2017 Jan 31;5:2050312117690404. doi: 10.1177/2050312117690404. eCollection 2017.


Oocyte shuttle, a recombinant protein transporting donor DNA into the Xenopus oocyte in situ.

Rungger D, Muster L, Georgiev O, Rungger-Brändle E.

Biol Open. 2017 Feb 15;6(2):290-295. doi: 10.1242/bio.022376.


Clinical characteristics, treatment patterns, and socio-economic burden of COPD in Bulgaria.

Kamusheva M, Dimitrova M, van Boven JF, Postma MJ, van der Molen T, Kocks JW, Mitov K, Doneva M, Petrova D, Georgiev O, Petkova V, Petrova G.

J Med Econ. 2017 May;20(5):503-509. doi: 10.1080/13696998.2017.1279620. Epub 2017 Jan 23.


Mapping of unmethylated sites in rDNA repeats in barley NOR deletion line.

Dimitrova AD, Georgiev O, Mishev K, Tzvetkov S, Ananiev ED, Karagyozov L.

J Plant Physiol. 2016 Oct 20;205:97-104. doi: 10.1016/j.jplph.2016.07.019. Epub 2016 Sep 17.


8-isoprostanes and resistin as markers of vascular damage in non-hypersomnolent obstructive sleep apnoea patients.

Cherneva RV, Cherneva ZV, Georgiev OB, Petrova DS, Petrova JI.

Clin Physiol Funct Imaging. 2017 Nov;37(6):695-702. doi: 10.1111/cpf.12361. Epub 2016 Jun 3.


Transcription enhancers as major determinants of SV40 polyomavirus growth efficiency and host cell tropism.

Schmidt K, Keiser S, Günther V, Georgiev O, Hirsch HH, Schaffner W, Bethge T.

J Gen Virol. 2016 Jul;97(7):1597-603. doi: 10.1099/jgv.0.000487. Epub 2016 Apr 21.


Short-lived mammals (shrew, mouse) have a less robust metal-responsive transcription factor than humans and bats.

Schmidt K, Steiner K, Petrov B, Georgiev O, Schaffner W.

Biometals. 2016 Jun;29(3):423-32. doi: 10.1007/s10534-016-9926-4. Epub 2016 Apr 11.


Risk factors for lung diseases after renal transplantation.

Pencheva VP, Petrova DS, Genov DK, Georgiev OB.

J Res Med Sci. 2015 Dec;20(12):1127-32. doi: 10.4103/1735-1995.172978.


Adeno-Associated Virus Type 2 Rep68 Can Bind to Consensus Rep-Binding Sites on the Herpes Simplex Virus 1 Genome.

Seyffert M, Glauser DL, Tobler K, Georgiev O, Vogel R, Vogt B, Agúndez L, Linden M, Büning H, Ackermann M, Fraefel C.

J Virol. 2015 Nov;89(21):11150-8. doi: 10.1128/JVI.01370-15. Epub 2015 Aug 19.


Versican upregulation in Sézary cells alters growth, motility and resistance to chemotherapy.

Fujii K, Karpova MB, Asagoe K, Georgiev O, Dummer R, Urosevic-Maiwald M.

Leukemia. 2015 Oct;29(10):2024-32. doi: 10.1038/leu.2015.103. Epub 2015 Apr 27.


Emergence of infectious simian virus 40 whose AT tract in the replication origin/early promoter region is substituted by cellular or viral DNAs.

Keiser S, Schmidt K, Bethge T, Steiger J, Hirsch HH, Schaffner W, Georgiev O.

J Gen Virol. 2015 Mar;96(Pt 3):601-6. doi: 10.1099/vir.0.071274-0. Epub 2014 Nov 10.


The legless lizard Anguis fragilis (slow worm) has a potent metal-responsive transcription factor 1 (MTF-1).

Georgiev O, Günther V, Steiner K, Schönrath K, Schaffner W.

Biol Chem. 2014 Apr;395(4):425-31. doi: 10.1515/hsz-2013-0293.


[Polycystic ovarian syndrome and obstructive sleep apnea].

Gateva A, Kamenov Z, Mondeshki Ts, Bilyukov R, Georgiev O.

Akush Ginekol (Sofiia). 2013;52(3):63-8. Review. Bulgarian.


Real life clinical study design supporting the effectiveness of extra-fine inhaled beclomethasone/formoterol at the level of small airways of asthmatics.

Popov TA, Petrova D, Kralimarkova TZ, Ivanov Y, Popova T, Peneva M, Odzhakova T, Ilieva Y, Yakovliev P, Lazarova T, Georgiev O, Hodzhev V, Hodzheva E, Staevska MT, Dimitrov VD.

Pulm Pharmacol Ther. 2013 Dec;26(6):624-9. doi: 10.1016/j.pupt.2013.06.002. Epub 2013 Jun 14.


Resistin - the link between adipose tissue dysfunction and insulin resistance in patients with obstructive sleep apnea.

Cherneva RV, Georgiev OB, Petrova DS, Mondeshki TL, Ruseva SR, Cakova AD, Mitev VI.

J Diabetes Metab Disord. 2013 Jan 10;12(1):5. doi: 10.1186/2251-6581-12-5.


A recent evolutionary change affects a regulatory element in the human FOXP2 gene.

Maricic T, Günther V, Georgiev O, Gehre S, Curlin M, Schreiweis C, Naumann R, Burbano HA, Meyer M, Lalueza-Fox C, de la Rasilla M, Rosas A, Gajovic S, Kelso J, Enard W, Schaffner W, Pääbo S.

Mol Biol Evol. 2013 Apr;30(4):844-52. doi: 10.1093/molbev/mss271. Epub 2012 Nov 28.


The role of small heat-shock protein αB-crystalline (HspB5) in COPD pathogenesis.

Cherneva RV, Georgiev OB, Petrova DS, Trifonova NL, Stamenova M, Ivanova V, Vlasov VI.

Int J Chron Obstruct Pulmon Dis. 2012;7:633-40. doi: 10.2147/COPD.S34929. Epub 2012 Oct 4.


Polyglutamine tracts as modulators of transcriptional activation from yeast to mammals.

Atanesyan L, Günther V, Dichtl B, Georgiev O, Schaffner W.

Biol Chem. 2012 Jan;393(1-2):63-70. doi: 10.1515/BC-2011-252.


Simian virus 40 strains with novel properties generated by replacing the viral enhancer with synthetic oligonucleotides.

Günther V, Strassen T, Lindert U, Dagani P, Waldvogel D, Georgiev O, Schaffner W, Bethge T.

J Virol. 2012 Mar;86(6):3135-42. doi: 10.1128/JVI.06293-11. Epub 2012 Jan 11.


Dissection of Drosophila MTF-1 reveals a domain for differential target gene activation upon copper overload vs. copper starvation.

Günther V, Waldvogel D, Nosswitz M, Georgiev O, Schaffner W.

Int J Biochem Cell Biol. 2012 Feb;44(2):404-11. doi: 10.1016/j.biocel.2011.11.016. Epub 2011 Nov 26.


A conserved cysteine cluster, essential for transcriptional activity, mediates homodimerization of human metal-responsive transcription factor-1 (MTF-1).

Günther V, Davis AM, Georgiev O, Schaffner W.

Biochim Biophys Acta. 2012 Feb;1823(2):476-83. doi: 10.1016/j.bbamcr.2011.10.006. Epub 2011 Oct 25.


Characterization of MtnE, the fifth metallothionein member in Drosophila.

Atanesyan L, Günther V, Celniker SE, Georgiev O, Schaffner W.

J Biol Inorg Chem. 2011 Oct;16(7):1047-56. doi: 10.1007/s00775-011-0825-4. Epub 2011 Aug 26.


Toxicity of Alzheimer's disease-associated Aβ peptide is ameliorated in a Drosophila model by tight control of zinc and copper availability.

Hua H, Münter L, Harmeier A, Georgiev O, Multhaup G, Schaffner W.

Biol Chem. 2011 Oct;392(10):919-26. doi: 10.1515/BC.2011.084. Epub 2011 Jul 30.


Distorted copper homeostasis with decreased sensitivity to cisplatin upon chaperone Atox1 deletion in Drosophila.

Hua H, Günther V, Georgiev O, Schaffner W.

Biometals. 2011 Jun;24(3):445-53. doi: 10.1007/s10534-011-9438-1. Epub 2011 Apr 5.


The parkin mutant phenotype in the fly is largely rescued by metal-responsive transcription factor (MTF-1).

Saini N, Georgiev O, Schaffner W.

Mol Cell Biol. 2011 May;31(10):2151-61. doi: 10.1128/MCB.05207-11. Epub 2011 Mar 7.


Extended lifespan of Drosophila parkin mutants through sequestration of redox-active metals and enhancement of anti-oxidative pathways.

Saini N, Oelhafen S, Hua H, Georgiev O, Schaffner W, Büeler H.

Neurobiol Dis. 2010 Oct;40(1):82-92. doi: 10.1016/j.nbd.2010.05.011. Epub 2010 May 17.


The Drosophila copper transporter Ctr1C functions in male fertility.

Steiger D, Fetchko M, Vardanyan A, Atanesyan L, Steiner K, Turski ML, Thiele DJ, Georgiev O, Schaffner W.

J Biol Chem. 2010 May 28;285(22):17089-97. doi: 10.1074/jbc.M109.090282. Epub 2010 Mar 29.


EGFR and hTERT Expression as a Diagnostic Approach for Non-small Cell Lung Cancer in High Risk Groups.

Cherneva R, Georgiev O, Dimova I, Rukova B, Petrov D, Toncheva D.

Biomark Cancer. 2010 Apr 8;2:57-63. doi: 10.4137/BIC.S3383. eCollection 2010.


Obstructive sleep apnea syndrome and depressive symptoms.

Bilyukov RG, Georgiev OB, Petrova DS, Mondeshki TL, Milanova VK.

Folia Med (Plovdiv). 2009 Jul-Sep;51(3):18-24. Review.


Human copper transporter Ctr1 is functional in Drosophila, revealing a high degree of conservation between mammals and insects.

Hua H, Georgiev O, Schaffner W, Steiger D.

J Biol Inorg Chem. 2010 Jan;15(1):107-13. doi: 10.1007/s00775-009-0599-0. Epub 2009 Oct 25.


Clinical usefulness of alpha-crystallin antibodies in non-small cell lung cancer patients.

Cherneva R, Petrov D, Georgiev O, Trifonova N.

Interact Cardiovasc Thorac Surg. 2010 Jan;10(1):14-7. doi: 10.1510/icvts.2009.213546. Epub 2009 Oct 1.


Metal-responsive transcription factor 1 (MTF-1) activity is regulated by a nonconventional nuclear localization signal and a metal-responsive transactivation domain.

Lindert U, Cramer M, Meuli M, Georgiev O, Schaffner W.

Mol Cell Biol. 2009 Dec;29(23):6283-93. doi: 10.1128/MCB.00847-09. Epub 2009 Sep 21.


Epidermal growth factor receptor gene copy number changes in lung cancer.

Cherneva RV, Georgiev OB, Petrov DB, Dimova II, Toncheva DI.

Folia Med (Plovdiv). 2009 Apr-Jun;51(2):12-8.


Expression profile of the small heat-shock protein alpha-B-crystallin in operated-on non-small-cell lung cancer patients: clinical implication.

Cherneva R, Petrov D, Georgiev O, Slavova Y, Toncheva D, Stamenova M, Trifonova N.

Eur J Cardiothorac Surg. 2010 Jan;37(1):44-50. doi: 10.1016/j.ejcts.2009.06.038. Epub 2009 Aug 3.


Role of amyloid-beta glycine 33 in oligomerization, toxicity, and neuronal plasticity.

Harmeier A, Wozny C, Rost BR, Munter LM, Hua H, Georgiev O, Beyermann M, Hildebrand PW, Weise C, Schaffner W, Schmitz D, Multhaup G.

J Neurosci. 2009 Jun 10;29(23):7582-90. doi: 10.1523/JNEUROSCI.1336-09.2009.


Mercury and cadmium trigger expression of the copper importer Ctr1B, which enables Drosophila to thrive on heavy metal-loaded food.

Balamurugan K, Hua H, Georgiev O, Schaffner W.

Biol Chem. 2009 Feb;390(2):109-13. doi: 10.1515/BC.2009.020.


Drosophila bloom helicase maintains genome integrity by inhibiting recombination between divergent DNA sequences.

Kappeler M, Kranz E, Woolcock K, Georgiev O, Schaffner W.

Nucleic Acids Res. 2008 Dec;36(21):6907-17. doi: 10.1093/nar/gkn793. Epub 2008 Oct 31.


Dumpy-30 family members as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila.

Vardanyan A, Atanesyan L, Egli D, Raja SJ, Steinmann-Zwicky M, Renkawitz-Pohl R, Georgiev O, Schaffner W.

BMC Dev Biol. 2008 Jun 27;8:68. doi: 10.1186/1471-213X-8-68.


Copper sensing function of Drosophila metal-responsive transcription factor-1 is mediated by a tetranuclear Cu(I) cluster.

Chen X, Hua H, Balamurugan K, Kong X, Zhang L, George GN, Georgiev O, Schaffner W, Giedroc DP.

Nucleic Acids Res. 2008 May;36(9):3128-38. doi: 10.1093/nar/gkn103. Epub 2008 Apr 13.


Visualization of cancer cells by means of the fluorescent EGFP-barnase protein.

Lebedenko EN, Balandin TG, Edelweiss EF, Georgiev O, Moiseeva ES, Petrov RV, Deyev SM.

Dokl Biochem Biophys. 2007 May-Jun;414:120-3. No abstract available.


Gemifloxacin once daily for 5 days versus 7 days for the treatment of community-acquired pneumonia: a randomized, multicentre, double-blind study.

File TM Jr, Mandell LA, Tillotson G, Kostov K, Georgiev O.

J Antimicrob Chemother. 2007 Jul;60(1):112-20. Epub 2007 May 30.


Mapping protein-protein interactions for the yeast ABC transporter Ycf1p by integrated split-ubiquitin membrane yeast two-hybrid analysis.

Paumi CM, Menendez J, Arnoldo A, Engels K, Iyer KR, Thaminy S, Georgiev O, Barral Y, Michaelis S, Stagljar I.

Mol Cell. 2007 Apr 13;26(1):15-25.


Copper homeostasis in Drosophila by complex interplay of import, storage and behavioral avoidance.

Balamurugan K, Egli D, Hua H, Rajaram R, Seisenbacher G, Georgiev O, Schaffner W.

EMBO J. 2007 Feb 21;26(4):1035-44. Epub 2007 Feb 8.

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