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Defining a pathological role for the vasculature in the development of fibrosis and pulmonary hypertension in interstitial lung disease.

George PM, Mitchell JA.

Am J Physiol Lung Cell Mol Physiol. 2019 Aug 21. doi: 10.1152/ajplung.00330.2019. [Epub ahead of print] No abstract available.


King's Brief Interstitial Lung Disease questionnaire: responsiveness and minimum clinically important difference.

Nolan CM, Birring SS, Maddocks M, Maher TM, Patel S, Barker RE, Jones SE, Walsh JA, Wynne SC, George PM, Man WD.

Eur Respir J. 2019 Sep 5;54(3). pii: 1900281. doi: 10.1183/13993003.00281-2019. Print 2019 Sep.


Evaluation of a surgical task sharing training programme's logbook system in Sierra Leone.

Svendsen ØV, Helgerud C, van Duinen AJ, Salvesen Ø, George PM, Bolkan HA.

BMC Med Educ. 2019 Jun 11;19(1):198. doi: 10.1186/s12909-019-1647-2.


In patients with idiopathic pulmonary fibrosis the presence of hiatus hernia is associated with disease progression and mortality.

Mackintosh JA, Desai SR, Adamali H, Patel K, Chua F, Devaraj A, Kouranos V, Kokosi M, Margaritopoulos G, Renzoni EA, Wells AU, Molyneaux PL, Kumar S, Maher TM, George PM.

Eur Respir J. 2019 May 23;53(5). pii: 1802412. doi: 10.1183/13993003.02412-2018. Print 2019 May. No abstract available.


Comparative aspects of the care of familial hypercholesterolemia in the "Ten Countries Study".

Pang J, Chan DC, Hu M, Muir LA, Kwok S, Charng MJ, Florkowski CM, George PM, Lin J, Loi DD, Marais AD, Nawawi HM, Gonzalez-Santos LE, Su TC, Truong TH, Santos RD, Soran H, Tomlinson B, Yamashita S, Ademi Z, Watts GF.

J Clin Lipidol. 2019 Mar - Apr;13(2):287-300. doi: 10.1016/j.jacl.2019.01.009. Epub 2019 Jan 25.


Lung transplantation for idiopathic pulmonary fibrosis.

George PM, Patterson CM, Reed AK, Thillai M.

Lancet Respir Med. 2019 Mar;7(3):271-282. doi: 10.1016/S2213-2600(18)30502-2. Epub 2019 Feb 6. Review.


Gait speed and prognosis in patients with idiopathic pulmonary fibrosis: a prospective cohort study.

Nolan CM, Maddocks M, Maher TM, Banya W, Patel S, Barker RE, Jones SE, George PM, Cullinan P, Man WD.

Eur Respir J. 2019 Feb 7;53(2). pii: 1801186. doi: 10.1183/13993003.01186-2018. Print 2019 Feb.


The potential impact of azithromycin in idiopathic pulmonary fibrosis.

Macaluso C, Maritano Furcada J, Alzaher O, Chaube R, Chua F, Wells AU, Maher TM, George PM, Renzoni EA, Molyneaux PL.

Eur Respir J. 2019 Feb 14;53(2). pii: 1800628. doi: 10.1183/13993003.00628-2018. Print 2019 Feb. No abstract available.


Validity of a Novel Point-of-Care Troponin Assay for Single-Test Rule-Out of Acute Myocardial Infarction.

Pickering JW, Young JM, George PM, Watson AS, Aldous SJ, Troughton RW, Pemberton CJ, Richards AM, Cullen LA, Than MP.

JAMA Cardiol. 2018 Nov 1;3(11):1108-1112. doi: 10.1001/jamacardio.2018.3368.


Effect of ambulatory oxygen on quality of life for patients with fibrotic lung disease (AmbOx): a prospective, open-label, mixed-method, crossover randomised controlled trial.

Visca D, Mori L, Tsipouri V, Fleming S, Firouzi A, Bonini M, Pavitt MJ, Alfieri V, Canu S, Bonifazi M, Boccabella C, De Lauretis A, Stock CJW, Saunders P, Montgomery A, Hogben C, Stockford A, Pittet M, Brown J, Chua F, George PM, Molyneaux PL, Margaritopoulos GA, Kokosi M, Kouranos V, Russell AM, Birring SS, Chetta A, Maher TM, Cullinan P, Hopkinson NS, Banya W, Whitty JA, Adamali H, Spencer LG, Farquhar M, Sestini P, Wells AU, Renzoni EA.

Lancet Respir Med. 2018 Oct;6(10):759-770. doi: 10.1016/S2213-2600(18)30289-3. Epub 2018 Aug 28.


Engineered stem cell mimics to enhance stroke recovery.

George PM, Oh B, Dewi R, Hua T, Cai L, Levinson A, Liang X, Krajina BA, Bliss TM, Heilshorn SC, Steinberg GK.

Biomaterials. 2018 Sep;178:63-72. doi: 10.1016/j.biomaterials.2018.06.010. Epub 2018 Jun 14.


Restrictive lung defects: parenchymal, chest wall and neuromuscular.

Shanks AM, Desai SR, Rice A, Thomas SR, Polkey MI, George PM.

Thorax. 2018 Oct;73(10):989-991. doi: 10.1136/thoraxjnl-2018-211895. Epub 2018 Jun 7.


Monitoring Serious Adverse Events in the Sierra Leone Trial to Introduce a Vaccine Against Ebola.

Jarrett OD, Seward JF, Fombah AE, Lindblad R, Jalloh MI, El-Khorazaty J, Dawson P, Burton D, Zucker J, Carr W, Bah MM, Deen GF, George PM, James F, Lisk DR, Pratt D, Russell JBW, Sandy JD, Turay P, Hamel MJ, Schrag SJ, Walker RE, Samai M, Goldstein ST.

J Infect Dis. 2018 May 18;217(suppl_1):S24-S32. doi: 10.1093/infdis/jiy042.


Health Conditions in an Adult Population in Sierra Leone: Data Reported From the Sierra Leone Trial to Introduce a Vaccine Against Ebola (STRIVE).

Fombah AE, Goldstein ST, Jarrett OD, Jalloh MI, El-Khorazaty J, Lisk DR, Legardy-Williams J, Pratt DA, George PM, Russell JBW, Schrag SJ, Dawson P, Deen GF, Carr W, Lindblad R, James F, Bah MM, Yillia JF, Sandy JD, Turay PE, Conteh MA, Slutsker L, Mahon BE, Samai M, Seward JF.

J Infect Dis. 2018 May 18;217(suppl_1):S75-S80. doi: 10.1093/infdis/jix603.


Copy number variants implicate cardiac function and development pathways in earthquake-induced stress cardiomyopathy.

Lacey CJ, Doudney K, Bridgman PG, George PM, Mulder RT, Zarifeh JJ, Kimber B, Cadzow MJ, Black MA, Merriman TR, Lehnert K, Bickley VM, Pearson JF, Cameron VA, Kennedy MA.

Sci Rep. 2018 May 15;8(1):7548. doi: 10.1038/s41598-018-25827-5.


Detectable High-Sensitivity Cardiac Troponin within the Population Reference Interval Conveys High 5-Year Cardiovascular Risk: An Observational Study.

Than MP, Aldous SJ, Troughton RW, Pemberton CJ, Richards AM, Frampton CMA, Florkowski CM, George PM, Bailey S, Young JM, Cullen L, Greenslade JH, Parsonage WA, Everett BM, Peacock WF, Jaffe AS, Pickering JW.

Clin Chem. 2018 Jul;64(7):1044-1053. doi: 10.1373/clinchem.2017.285700. Epub 2018 May 14.


A stepwise composite echocardiographic score predicts severe pulmonary hypertension in patients with interstitial lung disease.

Bax S, Bredy C, Kempny A, Dimopoulos K, Devaraj A, Walsh S, Jacob J, Nair A, Kokosi M, Keir G, Kouranos V, George PM, McCabe C, Wilde M, Wells A, Li W, Wort SJ, Price LC.

ERJ Open Res. 2018 May 4;4(2). pii: 00124-2017. doi: 10.1183/23120541.00124-2017. eCollection 2018 Apr. Erratum in: ERJ Open Res. 2018 Jul 31;4(3):.


Rapidly Progressive Cystic Lung Disease.

Rogers C, Kent-Bramer J, Devaraj A, Nicholson AG, Molyneaux PL, Wells AU, Saikia S, Maher TM, George PM.

Am J Respir Crit Care Med. 2018 Jul 15;198(2):264. doi: 10.1164/rccm.201801-0161IM. No abstract available.


Plasma elemental responses to red meat ingestion in healthy young males and the effect of cooking method.

Barnett MPG, Chiang VSC, Milan AM, Pundir S, Walmsley TA, Grant S, Markworth JF, Quek SY, George PM, Cameron-Smith D.

Eur J Nutr. 2019 Apr;58(3):1047-1054. doi: 10.1007/s00394-018-1620-6. Epub 2018 Feb 14.


Medical Officers in Sierra Leone: Surgical Training Opportunities, Challenges and Aspirations.

Wilks L, Leather A, George PM, Kamara TB.

J Surg Educ. 2018 Jul - Aug;75(4):1028-1033. doi: 10.1016/j.jsurg.2018.01.003. Epub 2018 Feb 13.


Erratum to: Plasma betaine concentrations correlate with plasma cortisol but not with C-reactive protein in an elderly population

Lever M, Storer MK, Lewis JG, George PM, Chambers ST.

Clin Chem Lab Med. 2017 Sep 12;50(9). pii: /j/cclm.2012.50.issue-9/cclm-2017-9911/cclm-2017-9911.xml. doi: 10.1515/cclm-2017-9911. No abstract available.


Pulmonary hypertension in interstitial lung disease: Limitations of echocardiography compared to cardiac catheterization.

Keir GJ, Wort SJ, Kokosi M, George PM, Walsh SLF, Jacob J, Price L, Bax S, Renzoni EA, Maher TM, MacDonald P, Hansell DM, Wells AU.

Respirology. 2018 Jul;23(7):687-694. doi: 10.1111/resp.13250. Epub 2018 Jan 12.


Conductive polymer scaffolds to improve neural recovery.

Song S, George PM.

Neural Regen Res. 2017 Dec;12(12):1976-1978. doi: 10.4103/1673-5374.221151. No abstract available.


Disease staging and sub setting of interstitial lung disease associated with systemic sclerosis: impact on therapy.

George PM, Wells AU.

Expert Rev Clin Immunol. 2018 Feb;14(2):127-135. doi: 10.1080/1744666X.2018.1427064. Epub 2018 Jan 20.


Compound Heterozygous Inheritance of Mutations in Coenzyme Q8A Results in Autosomal Recessive Cerebellar Ataxia and Coenzyme Q10 Deficiency in a Female Sib-Pair.

Jacobsen JC, Whitford W, Swan B, Taylor J, Love DR, Hill R, Molyneux S, George PM, Mackay R, Robertson SP, Snell RG, Lehnert K.

JIMD Rep. 2018;42:31-36. doi: 10.1007/8904_2017_73. Epub 2017 Nov 21.


ICare-ACS (Improving Care Processes for Patients With Suspected Acute Coronary Syndrome): A Study of Cross-System Implementation of a National Clinical Pathway.

Than MP, Pickering JW, Dryden JM, Lord SJ, Aitken SA, Aldous SJ, Allan KE, Ardagh MW, Bonning JWN, Callender R, Chapman LRE, Christiansen JP, Cromhout APJ, Cullen L, Deely JM, Devlin GP, Ferrier KA, Florkowski CM, Frampton CMA, George PM, Hamilton GJ, Jaffe AS, Kerr AJ, Larkin GL, Makower RM, Matthews TJE, Parsonage WA, Peacock WF, Peckler BF, van Pelt NC, Poynton L, Richards AM, Scott AG, Simmonds MB, Smyth D, Thomas OP, To ACY, Du Toit SA, Troughton RW, Yates KM; ICare-ACS Implementation Group.

Circulation. 2018 Jan 23;137(4):354-363. doi: 10.1161/CIRCULATIONAHA.117.031984. Epub 2017 Nov 14.


A Risk Assessment Score and Initial High-sensitivity Troponin Combine to Identify Low Risk of Acute Myocardial Infarction in the Emergency Department.

Pickering JW, Flaws D, Smith SW, Greenslade J, Cullen L, Parsonage W, Carlton E, Mark Richards A, Troughton R, Pemberton C, George PM, Than MP.

Acad Emerg Med. 2018 Apr;25(4):434-443. doi: 10.1111/acem.13343. Epub 2017 Dec 11.


Electrical preconditioning of stem cells with a conductive polymer scaffold enhances stroke recovery.

George PM, Bliss TM, Hua T, Lee A, Oh B, Levinson A, Mehta S, Sun G, Steinberg GK.

Biomaterials. 2017 Oct;142:31-40. doi: 10.1016/j.biomaterials.2017.07.020. Epub 2017 Jul 12.


Chemical and biological assessment of metal organic frameworks (MOFs) in pulmonary cells and in an acute in vivo model: relevance to pulmonary arterial hypertension therapy.

Mohamed NA, Davies RP, Lickiss PD, Ahmetaj-Shala B, Reed DM, Gashaw HH, Saleem H, Freeman GR, George PM, Wort SJ, Morales-Cano D, Barreira B, Tetley TD, Chester AH, Yacoub MH, Kirkby NS, Moreno L, Mitchell JA.

Pulm Circ. 2017 Jul-Sep;7(3):643-653. doi: 10.1177/2045893217710224. Epub 2017 Jun 27.


Cost-Effectiveness of Two Government District Hospitals in Sub-Saharan Africa.

Grimes CE, Law R, Dare A, Day N, Reshamwalla S, Murowa M, George PM, Kamara TB, Mkandawire NC, Leather AJM, Lavy CBD.

World J Surg. 2017 Sep;41(9):2187-2192. doi: 10.1007/s00268-017-4007-6.


Design of the Familial Hypercholesterolaemia Australasia Network Registry: Creating Opportunities for Greater International Collaboration.

Bellgard MI, Walker CE, Napier KR, Lamont L, Hunter AA, Render L, Radochonski M, Pang J, Pedrotti A, Sullivan DR, Kostner K, Bishop W, George PM, O'Brien RC, Clifton PM, Bockxmeer FMV, Nicholls SJ, Hamilton-Craig I, Dawkins HJ, Watts GF.

J Atheroscler Thromb. 2017 Oct 1;24(10):1075-1084. doi: 10.5551/jat.37507. Epub 2017 Mar 24.


Pirfenidone for the treatment of idiopathic pulmonary fibrosis.

George PM, Wells AU.

Expert Rev Clin Pharmacol. 2017 May;10(5):483-491. doi: 10.1080/17512433.2017.1295846. Epub 2017 Mar 7. Review.


Is N,N-dimethylglycine N-oxide a choline and betaine metabolite?

Lever M, McEntyre CJ, George PM, Chambers ST.

Biol Chem. 2017 Jun 27;398(7):775-784. doi: 10.1515/hsz-2016-0261.


Deciphering a macro-troponin I complex; a case report.

Chew-Harris JS, Brennan SO, Florkowski CM, Troughton R, George PM.

Clin Chem Lab Med. 2017 Mar 1;55(4):e77-e79. doi: 10.1515/cclm-2016-0490. No abstract available.


An emerging interstitial lung disease.

George PM, Devaraj A, Nicholson AG, Chua F.

Lancet Respir Med. 2016 Sep;4(9):762. doi: 10.1016/S2213-2600(16)30242-9. No abstract available.


Heart Fatty Acid Binding Protein and cardiac troponin: development of an optimal rule-out strategy for acute myocardial infarction.

Young JM, Pickering JW, George PM, Aldous SJ, Wallace J, Frampton CM, Troughton RW, Richards MA, Greenslade JH, Cullen L, Than MP.

BMC Emerg Med. 2016 Aug 31;16(1):34. doi: 10.1186/s12873-016-0089-y.


Sudden Cardiac Death Due to Deficiency of the Mitochondrial Inorganic Pyrophosphatase PPA2.

Kennedy H, Haack TB, Hartill V, Mataković L, Baumgartner ER, Potter H, Mackay R, Alston CL, O'Sullivan S, McFarland R, Connolly G, Gannon C, King R, Mead S, Crozier I, Chan W, Florkowski CM, Sage M, Höfken T, Alhaddad B, Kremer LS, Kopajtich R, Feichtinger RG, Sperl W, Rodenburg RJ, Minet JC, Dobbie A, Strom TM, Meitinger T, George PM, Johnson CA, Taylor RW, Prokisch H, Doudney K, Mayr JA.

Am J Hum Genet. 2016 Sep 1;99(3):674-682. doi: 10.1016/j.ajhg.2016.06.027. Epub 2016 Aug 11.


Hypoxic Challenge Testing for Fitness to Fly with Severe Asthma.

George PM, Orton C, Ward S, Menzies-Gow A, Hull JH.

Aerosp Med Hum Perform. 2016 Jun;87(6):571-574. doi: 10.3357/AMHP.4543.2016.


Unique albumin with two silent substitutions (540Thr→Ala and 546Ala→Ser): Insights into how albumin is recycled.

Brennan SO, Potter HC, Sheen CR, George PM.

Clin Chim Acta. 2016 Jun 1;457:125-9. doi: 10.1016/j.cca.2016.04.014. Epub 2016 Apr 14.


Moving Towards a More Aggressive and Comprehensive Model of Care for Children with Ebola.

Trehan I, Kelly T, Marsh RH, George PM, Callahan CW.

J Pediatr. 2016 Mar;170:28-33.e1-7. doi: 10.1016/j.jpeds.2015.11.054. Epub 2016 Jan 8. No abstract available.


Inter-rater agreement analysis of the Precise Diagnostic Score for suspected transient ischemic attack.

Cereda CW, George PM, Inoue M, Vora N, Olivot JM, Schwartz N, Lansberg MG, Kemp S, Mlynash M, Albers GW.

Int J Stroke. 2016 Jan;11(1):85-92. doi: 10.1177/1747493015607507. Erratum in: Int J Stroke. 2016 Apr;11(3):NP42-3.


The demographics of patients affected by surgical disease in district hospitals in two sub-Saharan African countries: a retrospective descriptive analysis.

Grimes CE, Billingsley ML, Dare AJ, Day N, George PM, Kamara TB, Mkandawire NC, Leather A, Lavy CB.

Springerplus. 2015 Dec 1;4:750. doi: 10.1186/s40064-015-1496-3. eCollection 2015.


Cough in interstitial lung disease.

Garner J, George PM, Renzoni E.

Pulm Pharmacol Ther. 2015 Dec;35:122-8. doi: 10.1016/j.pupt.2015.10.009. Epub 2015 Nov 3. Review.


Evaluation of Abbott Architect high-sensitivity troponin I assay for haemolysis interference.

Ryan JB, Wallace J, Sies CW, Florkowski CM, George PM.

Pathology. 2015 Dec;47(7):716-8. doi: 10.1097/PAT.0000000000000342. No abstract available.


Demographics of patients affected by surgical disease in rural hospitals in two sub-Saharan African countries: a retrospective analysis.

Grimes CE, Billingsley ML, Dare AJ, Day N, Mabey I, Naraghi S, George PM, Murowa M, Kamara TB, Mkandawire NC, Leather A, Lavy CB.

Lancet. 2015 Apr 27;385 Suppl 2:S3. doi: 10.1016/S0140-6736(15)60798-X. Epub 2015 Apr 26.


Novel TIA biomarkers identified by mass spectrometry-based proteomics.

George PM, Mlynash M, Adams CM, Kuo CJ, Albers GW, Olivot JM.

Int J Stroke. 2015 Dec;10(8):1204-11. doi: 10.1111/ijs.12603. Epub 2015 Aug 26.


Beware the dog that didn't bark: a tale of creatinine in acute kidney injury.

Chew-Harris JS, Pickering JW, George PM, Endre ZH, Florkowski CM.

Intern Med J. 2015 Aug;45(8):878-9. doi: 10.1111/imj.12826. No abstract available.


Novel Stroke Therapeutics: Unraveling Stroke Pathophysiology and Its Impact on Clinical Treatments.

George PM, Steinberg GK.

Neuron. 2015 Jul 15;87(2):297-309. doi: 10.1016/j.neuron.2015.05.041. Review.


Familial dysalbuminaemic hyperthyroxinaemia: a rapid and novel mass spectrometry approach to diagnosis.

Ryan JB, Brennan SO, Potter H, Wolmarans L, Florkowski CM, George PM.

Ann Clin Biochem. 2016 Jul;53(Pt 4):504-7. doi: 10.1177/0004563215598168. Epub 2015 Jul 13.


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