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Items: 1 to 50 of 69

1.

Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions.

Teixeira VH, Pipinikas CP, Pennycuick A, Lee-Six H, Chandrasekharan D, Beane J, Morris TJ, Karpathakis A, Feber A, Breeze CE, Ntolios P, Hynds RE, Falzon M, Capitanio A, Carroll B, Durrenberger PF, Hardavella G, Brown JM, Lynch AG, Farmery H, Paul DS, Chambers RC, McGranahan N, Navani N, Thakrar RM, Swanton C, Beck S, George PJ, Spira A, Campbell PJ, Thirlwell C, Janes SM.

Nat Med. 2019 Mar;25(3):517-525. doi: 10.1038/s41591-018-0323-0. Epub 2019 Jan 21.

PMID:
30664780
2.

The parasite-derived rOv-ASP-1 is an effective antigen-sparing CD4+ T cell-dependent adjuvant for the trivalent inactivated influenza vaccine, and functions in the absence of MyD88 pathway.

Jain S, George PJ, Deng W, Koussa J, Parkhouse K, Hensley SE, Jiang J, Lu J, Liu Z, Wei J, Zhan B, Bottazzi ME, Shen H, Lustigman S.

Vaccine. 2018 Jun 14;36(25):3650-3665. doi: 10.1016/j.vaccine.2018.05.029.

3.

CADM1 inhibits squamous cell carcinoma progression by reducing STAT3 activity.

Vallath S, Sage EK, Kolluri KK, Lourenco SN, Teixeira VS, Chimalapati S, George PJ, Janes SM, Giangreco A.

Sci Rep. 2016 Apr 1;6:24006. doi: 10.1038/srep24006.

4.

Positive (18)Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography Predicts Preinvasive Endobronchial Lesion Progression to Invasive Cancer.

Fraioli F, Kayani I, Smith LJ, Bomanji JB, Capitanio A, Falzon M, Carroll B, Navani N, Brown J, Thakrar RM, George PJ, Groves AM, Janes SM.

Am J Respir Crit Care Med. 2016 Mar 1;193(5):576-9. doi: 10.1164/rccm.201508-1617LE. No abstract available.

5.

Modulation of pro- and anti-inflammatory cytokines in active and latent tuberculosis by coexistent Strongyloides stercoralis infection.

George PJ, Pavan Kumar N, Jaganathan J, Dolla C, Kumaran P, Nair D, Banurekha VV, Shen K, Nutman TB, Babu S.

Tuberculosis (Edinb). 2015 Dec;95(6):822-828. doi: 10.1016/j.tube.2015.09.009. Epub 2015 Oct 8.

6.

Coincident diabetes mellitus modulates Th1-, Th2-, and Th17-cell responses in latent tuberculosis in an IL-10- and TGF-β-dependent manner.

Kumar NP, Moideen K, George PJ, Dolla C, Kumaran P, Babu S.

Eur J Immunol. 2016 Feb;46(2):390-9. doi: 10.1002/eji.201545973. Epub 2015 Nov 19.

7.

Impaired Cytokine but Enhanced Cytotoxic Marker Expression in Mycobacterium tuberculosis-Induced CD8+ T Cells in Individuals With Type 2 Diabetes and Latent Mycobacterium tuberculosis Infection.

Kumar NP, Moideen K, George PJ, Dolla C, Kumaran P, Babu S.

J Infect Dis. 2016 Mar 1;213(5):866-70. doi: 10.1093/infdis/jiv484. Epub 2015 Oct 20.

8.

Not always asthma: clinical and legal consequences of delayed diagnosis of laryngotracheal stenosis.

Nunn AC, Nouraei SA, George PJ, Sandhu GS, Nouraei SA.

Case Rep Otolaryngol. 2014;2014:325048. doi: 10.1155/2014/325048. Epub 2014 Dec 18.

9.

Coincident helminth infection modulates systemic inflammation and immune activation in active pulmonary tuberculosis.

George PJ, Kumar NP, Sridhar R, Hanna LE, Nair D, Banurekha VV, Nutman TB, Babu S.

PLoS Negl Trop Dis. 2014 Nov 6;8(11):e3289. doi: 10.1371/journal.pntd.0003289. eCollection 2014.

10.

Interleukin-10- and transforming growth factor β-independent regulation of CD8⁺ T cells expressing type 1 and type 2 cytokines in human lymphatic filariasis.

Anuradha R, George PJ, Kumaran P, Nutman TB, Babu S.

Clin Vaccine Immunol. 2014 Dec;21(12):1620-7. doi: 10.1128/CVI.00598-14. Epub 2014 Sep 24.

11.

Helminth infections coincident with active pulmonary tuberculosis inhibit mono- and multifunctional CD4+ and CD8+ T cell responses in a process dependent on IL-10.

George PJ, Anuradha R, Kumar NP, Sridhar R, Banurekha VV, Nutman TB, Babu S.

PLoS Pathog. 2014 Sep 11;10(9):e1004375. doi: 10.1371/journal.ppat.1004375. eCollection 2014 Sep.

12.

Diminished systemic and antigen-specific type 1, type 17, and other proinflammatory cytokines in diabetic and prediabetic individuals with latent Mycobacterium tuberculosis infection.

Kumar NP, George PJ, Kumaran P, Dolla CK, Nutman TB, Babu S.

J Infect Dis. 2014 Nov 15;210(10):1670-8. doi: 10.1093/infdis/jiu329. Epub 2014 Jun 6.

13.

Interleukin 1 (IL-1)- and IL-23-mediated expansion of filarial antigen-specific Th17 and Th22 cells in filarial lymphedema.

Anuradha R, George PJ, Chandrasekaran V, Kumaran PP, Nutman TB, Babu S.

Clin Vaccine Immunol. 2014 Jul;21(7):960-5. doi: 10.1128/CVI.00257-14. Epub 2014 May 7.

14.

Moving in an environment of induced sensorimotor incongruence does not influence pain sensitivity in healthy volunteers: a randomised within-subject experiment.

Wand BM, Szpak L, George PJ, Bulsara MK, O'Connell NE, Moseley GL.

PLoS One. 2014 Apr 7;9(4):e93701. doi: 10.1371/journal.pone.0093701. eCollection 2014.

15.

Expansion of parasite-specific CD4+ and CD8+ T cells expressing IL-10 superfamily cytokine members and their regulation in human lymphatic filariasis.

Anuradha R, George PJ, Hanna LE, Kumaran P, Chandrasekaran V, Nutman TB, Babu S.

PLoS Negl Trop Dis. 2014 Apr 3;8(4):e2762. doi: 10.1371/journal.pntd.0002762. eCollection 2014 Apr.

16.

Assessing self-perception in patients with chronic low back pain: development of a back-specific body-perception questionnaire.

Wand BM, James M, Abbaszadeh S, George PJ, Formby PM, Smith AJ, O'Connell NE.

J Back Musculoskelet Rehabil. 2014;27(4):463-73. doi: 10.3233/BMR-140467.

PMID:
24614834
17.

Illusory touch temporarily improves sensation in areas of chronic numbness: a brief communication.

Wand BM, Stephens SE, Mangharam EI, George PJ, Bulsara MK, O'Connell NE, Moseley GL.

Neurorehabil Neural Repair. 2014 Oct;28(8):797-9. doi: 10.1177/1545968314524827. Epub 2014 Feb 24.

PMID:
24566987
18.

Parasite-antigen driven expansion of IL-5(-) and IL-5(+) Th2 human subpopulations in lymphatic filariasis and their differential dependence on IL-10 and TGFβ.

Anuradha R, George PJ, Hanna LE, Chandrasekaran V, Kumaran PP, Nutman TB, Babu S.

PLoS Negl Trop Dis. 2014 Jan 30;8(1):e2658. doi: 10.1371/journal.pntd.0002658. eCollection 2014.

19.

Impact of EBUS-TBNA on modalities for tissue acquisition in patients with lung cancer.

José RJ, Shaw P, Taylor M, Lawrence DR, George PJ, Janes SM, Navani N.

QJM. 2014 Mar;107(3):201-6. doi: 10.1093/qjmed/hct233. Epub 2013 Nov 19.

20.

Microalbuminuria and C-reactive protein as a predictor of coronary artery disease in patients of acute chest pain.

Sharma S, Ghalaut VS, Dixit R, Kumar S, George PJ.

J Cardiovasc Dis Res. 2013 Mar;4(1):37-9. doi: 10.1016/j.jcdr.2013.02.014. Epub 2013 Feb 27.

21.

IL-4-, TGF-β-, and IL-1-dependent expansion of parasite antigen-specific Th9 cells is associated with clinical pathology in human lymphatic filariasis.

Anuradha R, George PJ, Hanna LE, Chandrasekaran V, Kumaran P, Nutman TB, Babu S.

J Immunol. 2013 Sep 1;191(5):2466-73. doi: 10.4049/jimmunol.1300911. Epub 2013 Aug 2.

22.

Management and prognosis of primary tracheal cancer: a national analysis.

Nouraei SM, Middleton SE, Nouraei SA, Virk JS, George PJ, Hayward M, Sandhu GS.

Laryngoscope. 2014 Jan;124(1):145-50. doi: 10.1002/lary.24123. Epub 2013 Jul 19.

PMID:
23868448
23.

Mislocalization of sensory information in people with chronic low back pain: a preliminary investigation.

Wand BM, Keeves J, Bourgoin C, George PJ, Smith AJ, O'Connell NE, Moseley GL.

Clin J Pain. 2013 Aug;29(8):737-43. doi: 10.1097/AJP.0b013e318274b320.

PMID:
23835768
24.

Diagnosis of laryngotracheal stenosis from routine pulmonary physiology using the expiratory disproportion index.

Nouraei SA, Nouraei SM, Patel A, Murphy K, Giussani DA, Koury EF, Brown JM, George PJ, Cummins AC, Sandhu GS.

Laryngoscope. 2013 Dec;123(12):3099-104. doi: 10.1002/lary.24192. Epub 2013 Oct 5.

PMID:
23686716
25.

Modulation of mycobacterial-specific Th1 and Th17 cells in latent tuberculosis by coincident hookworm infection.

George PJ, Anuradha R, Kumaran PP, Chandrasekaran V, Nutman TB, Babu S.

J Immunol. 2013 May 15;190(10):5161-8. doi: 10.4049/jimmunol.1203311. Epub 2013 Apr 10.

26.

Evidence of microbial translocation associated with perturbations in T cell and antigen-presenting cell homeostasis in hookworm infections.

George PJ, Anuradha R, Kumar NP, Kumaraswami V, Nutman TB, Babu S.

PLoS Negl Trop Dis. 2012;6(10):e1830. doi: 10.1371/journal.pntd.0001830. Epub 2012 Oct 4.

27.

Seeing it helps: movement-related back pain is reduced by visualization of the back during movement.

Wand BM, Tulloch VM, George PJ, Smith AJ, Goucke R, O'Connell NE, Moseley GL.

Clin J Pain. 2012 Sep;28(7):602-8.

PMID:
22699134
28.

Circulating microbial products and acute phase proteins as markers of pathogenesis in lymphatic filarial disease.

Anuradha R, George PJ, Pavan Kumar N, Fay MP, Kumaraswami V, Nutman TB, Babu S.

PLoS Pathog. 2012;8(6):e1002749. doi: 10.1371/journal.ppat.1002749. Epub 2012 Jun 7.

29.

Toll-like receptor- and filarial antigen-mediated, mitogen-activated protein kinase- and NF-κB-dependent regulation of angiogenic growth factors in filarial lymphatic pathology.

Babu S, Anuradha R, Kumar NP, George PJ, Kumaraswami V, Nutman TB.

Infect Immun. 2012 Jul;80(7):2509-18. doi: 10.1128/IAI.06179-11. Epub 2012 Apr 16.

30.

β-Catenin determines upper airway progenitor cell fate and preinvasive squamous lung cancer progression by modulating epithelial-mesenchymal transition.

Giangreco A, Lu L, Vickers C, Teixeira VH, Groot KR, Butler CR, Ilieva EV, George PJ, Nicholson AG, Sage EK, Watt FM, Janes SM.

J Pathol. 2012 Mar;226(4):575-87. doi: 10.1002/path.3962. Epub 2012 Jan 17.

31.

Filarial lymphatic pathology reflects augmented toll-like receptor-mediated, mitogen-activated protein kinase-mediated proinflammatory cytokine production.

Babu S, Anuradha R, Kumar NP, George PJ, Kumaraswami V, Nutman TB.

Infect Immun. 2011 Nov;79(11):4600-8. doi: 10.1128/IAI.05419-11. Epub 2011 Aug 29.

32.

Outcome of treating airway compromise due to bronchial stenosis with intralesional corticosteroids and cutting-balloon bronchoplasty.

Nouraei SA, Mills H, Butler CR, Ghufoor K, Sandhu GS, George PJ.

Otolaryngol Head Neck Surg. 2011 Oct;145(4):623-7. doi: 10.1177/0194599811413683. Epub 2011 Jul 11.

PMID:
21746843
33.

Genomic evidence of pre-invasive clonal expansion, dispersal and progression in bronchial dysplasia.

McCaughan F, Pipinikas CP, Janes SM, George PJ, Rabbitts PH, Dear PH.

J Pathol. 2011 Jun;224(2):153-9. doi: 10.1002/path.2887. Epub 2011 Apr 19.

34.

Progressive 3q amplification consistently targets SOX2 in preinvasive squamous lung cancer.

McCaughan F, Pole JC, Bankier AT, Konfortov BA, Carroll B, Falzon M, Rabbitts TH, George PJ, Dear PH, Rabbitts PH.

Am J Respir Crit Care Med. 2010 Jul 1;182(1):83-91. doi: 10.1164/rccm.201001-0005OC. Epub 2010 Mar 18.

35.

Microdissection molecular copy-number counting (microMCC)--unlocking cancer archives with digital PCR.

McCaughan F, Darai-Ramqvist E, Bankier AT, Konfortov BA, Foster N, George PJ, Rabbitts TH, Kost-Alimova M, Rabbitts PH, Dear PH.

J Pathol. 2008 Nov;216(3):307-16. doi: 10.1002/path.2413.

PMID:
18773450
36.

Clonal divergence in lung cancer development is associated with allelic loss on chromosome 4.

Banerjee AK, Read CA, Griffiths MH, George PJ, Rabbitts PH.

Genes Chromosomes Cancer. 2007 Sep;46(9):852-60.

PMID:
17592619
37.

Presence of telomerase activity with undetectable p16 gene mutation in Malaysian patients with brain tumor.

Jafri AM, Sarina S, George PJ, Nizam IM.

Med J Malaysia. 2004 Oct;59(4):480-5.

38.

Imaging bronchial carcinoma in situ: possible roles for combined positron emission tomography (PET)-CT.

Kayani I, Groves AM, Ell PJ, George PJ, Bomanji J.

Lancet Oncol. 2005 Mar;6(3):190. No abstract available.

PMID:
15737837
39.

Analysis of pediatric subdural empyema outcome in relation to computerized tomography brain scan.

Md Ralib AR, Ariff AR, Shuaib IL, Naing NN, George PJ, Abdullah JM.

Southeast Asian J Trop Med Public Health. 2004 Jun;35(2):434-44.

PMID:
15691152
40.

Preinvasive bronchial lesions: surveillance or intervention?

Banerjee AK, Rabbitts PH, George PJ.

Chest. 2004 May;125(5 Suppl):95S-6S. No abstract available.

PMID:
15136433
41.

Telomerase activity in Malaysian patients with central nervous system tumors.

Isa MN, Sulong S, Sidek MR, George PJ, Abdullah JM.

Southeast Asian J Trop Med Public Health. 2003 Dec;34(4):872-6.

PMID:
15115103
42.

Are all high-grade preinvasive lesions premalignant, and should they all be treated?

Banerjee AK, Rabbitts PH, George PJ.

Am J Respir Crit Care Med. 2002 May 15;165(10):1452-3; author reply 1453. No abstract available.

PMID:
12016112
43.

Fluorescence bronchoscopy for the early detection of lung cancer.

George PJ.

Thorax. 1999 Feb;54(2):180-3. Review. No abstract available.

44.

Upper airways sarcoidosis presenting as obstructive sleep apnoea.

Shah RN, Mills PR, George PJ, Wedzicha JA.

Thorax. 1998 Mar;53(3):232-3.

45.

Delays in the management of lung cancer.

George PJ.

Thorax. 1997 Feb;52(2):107-8. No abstract available.

46.

Clinical spectrum and mortality of extradural haematoma in rural versus urban India.

Sharma V, Mohanty S, George PJ.

Neurol India. 1995 Jul-Sep;43(3):144-148.

PMID:
29542510
47.

Preoperative laser therapy in a patient with resectable bronchogenic carcinoma and severe coronary artery disease.

Powney J, Scott AD, George PJ, Feneck RO, Wright J, Barnes NC.

Thorax. 1992 Dec;47(12):1075-6.

48.

Role of the Gianturco expandable metal stent in the management of tracheobronchial obstruction.

George PJ, Irving JD, Khaghani A, Dick R.

Cardiovasc Intervent Radiol. 1992 Nov-Dec;15(6):375-81.

PMID:
1477862
49.

Susceptibility status of five species of Japanese encephalitis vectors to insecticides from Kolar district, Karnataka.

Kulkarni SM, Geevarghese G, George PJ.

Indian J Med Res. 1992 Nov;95:297-300.

PMID:
1337898
50.

Medium dose rate endobronchial radiotherapy with caesium-137.

George PJ, Hadley JM, Mantell BS, Rudd RM.

Thorax. 1992 Jun;47(6):474-7. No abstract available.

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