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Exposure to passive nicotine vapor in male adolescent rats produces a withdrawal-like state and facilitates nicotine self-administration during adulthood.

Kallupi M, de Guglielmo G, Larrosa E, George O.

Eur Neuropsychopharmacol. 2019 Aug 26. pii: S0924-977X(19)30858-2. doi: 10.1016/j.euroneuro.2019.08.299. [Epub ahead of print]


Systemic Administration of the Cyclin-Dependent Kinase Inhibitor (S)-CR8 Selectively Reduces Escalated Ethanol Intake in Dependent Rats.

Goulding SP, de Guglielmo G, Carrette LLG, George O, Contet C.

Alcohol Clin Exp Res. 2019 Aug 12. doi: 10.1111/acer.14177. [Epub ahead of print]


Adolescent Facial Acne Vulgaris and Body Mass Index: Any Relationship?

Anaba LE, Ogunbiyi OA, George OA.

West Afr J Med. 2019 May-Aug;36(2):129-132.


Inactivation of a CRF-dependent amygdalofugal pathway reverses addiction-like behaviors in alcohol-dependent rats.

de Guglielmo G, Kallupi M, Pomrenze MB, Crawford E, Simpson S, Schweitzer P, Koob GF, Messing RO, George O.

Nat Commun. 2019 Mar 18;10(1):1238. doi: 10.1038/s41467-019-09183-0.


Genotoxic, Histopathological and Oxidative Stress Responses in Catfish, Clarias gariepinus, Exposed to Two Antifouling Paints.

George OO, Amaeze NH, Babatunde E, Otitoloju AA.

J Health Pollut. 2017 Dec 18;7(16):71-82. doi: 10.5696/2156-9614-7.16.71. eCollection 2017 Dec.


An enzymatic approach reverses nicotine dependence, decreases compulsive-like intake, and prevents relapse.

Kallupi M, Xue S, Zhou B, Janda KD, George O.

Sci Adv. 2018 Oct 17;4(10):eaat4751. doi: 10.1126/sciadv.aat4751. eCollection 2018 Oct.


Red colour venous flow in the suprasternal view: a red flag sign.

Mahajan S, Ghosh GC, George OK.

BMJ Case Rep. 2018 Sep 30;2018. pii: bcr-2018-227257. doi: 10.1136/bcr-2018-227257. No abstract available.


Fourteen-year-old boy with decreased appetite and pedal swelling.

Ghosh GC, S A, George OK.

Heart. 2018 Sep 21. pii: heartjnl-2018-313646. doi: 10.1136/heartjnl-2018-313646. [Epub ahead of print]


Adolescent cannabinoid exposure induces irritability-like behavior and cocaine cross-sensitization without affecting the escalation of cocaine self-administration in adulthood.

Kononoff J, Melas PA, Kallupi M, de Guglielmo G, Kimbrough A, Scherma M, Fadda P, Kandel DB, Kandel ER, George O.

Sci Rep. 2018 Sep 17;8(1):13893. doi: 10.1038/s41598-018-31921-5.


Voluntary urination control by brainstem neurons that relax the urethral sphincter.

Keller JA, Chen J, Simpson S, Wang EH, Lilascharoen V, George O, Lim BK, Stowers L.

Nat Neurosci. 2018 Sep;21(9):1229-1238. doi: 10.1038/s41593-018-0204-3. Epub 2018 Aug 13.


Systemic and Intra-Habenular Activation of the Orphan G Protein-Coupled Receptor GPR139 Decreases Compulsive-Like Alcohol Drinking and Hyperalgesia in Alcohol-Dependent Rats.

Kononoff J, Kallupi M, Kimbrough A, Conlisk D, de Guglielmo G, George O.

eNeuro. 2018 Jul 2;5(3). pii: ENEURO.0153-18.2018. doi: 10.1523/ENEURO.0153-18.2018. eCollection 2018 May-Jun.


Subthalamic nucleus high frequency stimulation prevents and reverses escalated cocaine use.

Pelloux Y, Degoulet M, Tiran-Cappello A, Cohen C, Lardeux S, George O, Koob GF, Ahmed SH, Baunez C.

Mol Psychiatry. 2018 Dec;23(12):2266-2276. doi: 10.1038/s41380-018-0080-y. Epub 2018 Jun 7.


An unusual case of cerebrovascular accident in a child.

Ghosh GC, Rajan RJ, Leena RV, George OK.

Eur Heart J Cardiovasc Imaging. 2018 Sep 1;19(9):1071. doi: 10.1093/ehjci/jey070. No abstract available.


Contemporary outcomes of percutaneous closure of patent ductus arteriosus in adolescents and adults.

P S, Jose J, George OK.

Indian Heart J. 2018 Mar - Apr;70(2):308-315. doi: 10.1016/j.ihj.2017.08.001. Epub 2017 Aug 9.


Carbon dioxide Angiography-Guided Renal-Related Interventions in Patients with Takayasu Arteritis and Renal Insufficiency.

Chacko S, Joseph G, Thomson V, George P, George O, Danda D.

Cardiovasc Intervent Radiol. 2018 Jul;41(7):998-1007. doi: 10.1007/s00270-018-1936-x. Epub 2018 Mar 16.


Inhibition of Glyoxalase 1 reduces alcohol self-administration in dependent and nondependent rats.

de Guglielmo G, Conlisk DE, Barkley-Levenson AM, Palmer AA, George O.

Pharmacol Biochem Behav. 2018 Apr;167:36-41. doi: 10.1016/j.pbb.2018.03.001. Epub 2018 Mar 2.


Radiation dose from percutaneous transluminal coronary angioplasty procedure performed using a flat detector for different clinical angiographic projections.

Varghese A, Livingstone RS, Varghese L, Dey S, Jose J, Thomson VS, George OK, George PV.

J Radiol Prot. 2018 Jun;38(2):511-524. doi: 10.1088/1361-6498/aaab71. Epub 2018 Jan 30.


Median and Dorsal Raphe Serotonergic Neurons Control Moderate Versus Compulsive Cocaine Intake.

Verheij MMM, Contet C, Karel P, Latour J, van der Doelen RHA, Geenen B, van Hulten JA, Meyer F, Kozicz T, George O, Koob GF, Homberg JR.

Biol Psychiatry. 2018 Jun 15;83(12):1024-1035. doi: 10.1016/j.biopsych.2017.10.031. Epub 2017 Nov 20.


Self-administered nicotine increases fat metabolism and suppresses weight gain in male rats.

Rupprecht LE, Kreisler AD, Spierling SR, de Guglielmo G, Kallupi M, George O, Donny EC, Zorrilla EP, Sved AF.

Psychopharmacology (Berl). 2018 Apr;235(4):1131-1140. doi: 10.1007/s00213-018-4830-y. Epub 2018 Jan 21.


An enzymatic advance in nicotine cessation therapy.

Xue S, Kallupi M, Zhou B, Smith LC, Miranda PO, George O, Janda KD.

Chem Commun (Camb). 2018 Feb 13;54(14):1686-1689. doi: 10.1039/c7cc09134f.


Individual differences in the neuropsychopathology of addiction.

George O, Koob GF.

Dialogues Clin Neurosci. 2017 Sep;19(3):217-229. Review.


The Heart of the Matter: Cardiac Manifestations of Endocrine Disease.

Binu AJ, Cherian KE, Kapoor N, Chacko ST, George O, Paul TV.

Indian J Endocrinol Metab. 2017 Nov-Dec;21(6):919-925. doi: 10.4103/ijem.IJEM_212_17. Review.


An Adult with Atrial Septal Defect Presenting with a Brain Abscess.

Nair BR, Jonathan E, Moorthy RK, Rajshekhar V, George O.

Asian J Neurosurg. 2017 Oct-Dec;12(4):743-745. doi: 10.4103/ajns.AJNS_194_14.


Dynorphin Counteracts Orexin in the Paraventricular Nucleus of the Thalamus: Cellular and Behavioral Evidence.

Matzeu A, Kallupi M, George O, Schweitzer P, Martin-Fardon R.

Neuropsychopharmacology. 2018 Apr;43(5):1010-1020. doi: 10.1038/npp.2017.250. Epub 2017 Oct 20.


CRF1 Receptor-Dependent Increases in Irritability-Like Behavior During Abstinence from Chronic Intermittent Ethanol Vapor Exposure.

Kimbrough A, de Guglielmo G, Kononoff J, Kallupi M, Zorrilla EP, George O.

Alcohol Clin Exp Res. 2017 Nov;41(11):1886-1895. doi: 10.1111/acer.13484. Epub 2017 Sep 22.


Compulsive-Like Sufentanil Vapor Self-Administration in Rats.

Vendruscolo JCM, Tunstall BJ, Carmack SA, Schmeichel BE, Lowery-Gionta EG, Cole M, George O, Vandewater SA, Taffe MA, Koob GF, Vendruscolo LF.

Neuropsychopharmacology. 2018 Mar;43(4):801-809. doi: 10.1038/npp.2017.172. Epub 2017 Aug 16.


Intermittent Access to Ethanol Drinking Facilitates the Transition to Excessive Drinking After Chronic Intermittent Ethanol Vapor Exposure.

Kimbrough A, Kim S, Cole M, Brennan M, George O.

Alcohol Clin Exp Res. 2017 Aug;41(8):1502-1509. doi: 10.1111/acer.13434. Epub 2017 Jul 5.


Nicotine Vapor Method to Induce Nicotine Dependence in Rodents.

Kallupi M, George O.

Curr Protoc Neurosci. 2017 Jul 5;80:8.41.1-8.41.10. doi: 10.1002/cpns.34.


Cebranopadol Blocks the Escalation of Cocaine Intake and Conditioned Reinstatement of Cocaine Seeking in Rats.

de Guglielmo G, Matzeu A, Kononoff J, Mattioni J, Martin-Fardon R, George O.

J Pharmacol Exp Ther. 2017 Sep;362(3):378-384. doi: 10.1124/jpet.117.241042. Epub 2017 Jun 23.


Deletion of α5 nicotine receptor subunits abolishes nicotinic aversive motivational effects in a manner that phenocopies dopamine receptor antagonism.

Grieder TE, George O, Yee M, Bergamini MA, Chwalek M, Maal-Bared G, Vargas-Perez H, van der Kooy D.

Eur J Neurosci. 2017 Jul;46(1):1673-1681. doi: 10.1111/ejn.13605. Epub 2017 Jun 21.


Cortical and amygdalar neuronal ensembles in alcohol seeking, drinking and withdrawal.

George O, Hope BT.

Neuropharmacology. 2017 Aug 1;122:107-114. doi: 10.1016/j.neuropharm.2017.04.031. Epub 2017 Apr 20. Review.


Alcohol Dependence Disrupts Amygdalar L-Type Voltage-Gated Calcium Channel Mechanisms.

Varodayan FP, de Guglielmo G, Logrip ML, George O, Roberto M.

J Neurosci. 2017 Apr 26;37(17):4593-4603. doi: 10.1523/JNEUROSCI.3721-16.2017. Epub 2017 Mar 31.


Voluntary induction and maintenance of alcohol dependence in rats using alcohol vapor self-administration.

de Guglielmo G, Kallupi M, Cole MD, George O.

Psychopharmacology (Berl). 2017 Jul;234(13):2009-2018. doi: 10.1007/s00213-017-4608-7. Epub 2017 Mar 24.


Genetic and Pharmacologic Manipulation of TLR4 Has Minimal Impact on Ethanol Consumption in Rodents.

Harris RA, Bajo M, Bell RL, Blednov YA, Varodayan FP, Truitt JM, de Guglielmo G, Lasek AW, Logrip ML, Vendruscolo LF, Roberts AJ, Roberts E, George O, Mayfield J, Billiar TR, Hackam DJ, Mayfield RD, Koob GF, Roberto M, Homanics GE.

J Neurosci. 2017 Feb 1;37(5):1139-1155. doi: 10.1523/JNEUROSCI.2002-16.2016. Epub 2016 Dec 16.


High-Frequency Stimulation of the Subthalamic Nucleus Blocks Compulsive-Like Re-Escalation of Heroin Taking in Rats.

Wade CL, Kallupi M, Hernandez DO, Breysse E, de Guglielmo G, Crawford E, Koob GF, Schweitzer P, Baunez C, George O.

Neuropsychopharmacology. 2017 Aug;42(9):1850-1859. doi: 10.1038/npp.2016.270. Epub 2016 Dec 5.


Transjugular balloon mitral valvotomy in a patient with severe kyphoscoliosis.

Joseph G, Varghese MJ, George OK.

Indian Heart J. 2016 Sep;68 Suppl 2:S11-S14. doi: 10.1016/j.ihj.2016.01.015. Epub 2016 Jan 29.


Authors' response.

Nair V, Madan H, Sofat S, Ganguli P, Jacob MJ, Datta R, Bharadwaj P, Sarkar RS, Pandit AJ, Nityanand S, Goel PK, Garg N, Gambhir S, George PV, Chandy S, Mathews V, George OK, Talwar KK, Bahl A, Marwah N, Bhatacharya A, Bhargava B, Airan B, Mohanty S, Patel CD, Sharma A, Bhatnagar S, Mondal A, Jose J, Srivastava A; for MI3 Trial.

Indian J Med Res. 2016 Jun;143(6):833. doi: 10.4103/0971-5916.192081. No abstract available.


Recruitment of a Neuronal Ensemble in the Central Nucleus of the Amygdala Is Required for Alcohol Dependence.

de Guglielmo G, Crawford E, Kim S, Vendruscolo LF, Hope BT, Brennan M, Cole M, Koob GF, George O.

J Neurosci. 2016 Sep 7;36(36):9446-53. doi: 10.1523/JNEUROSCI.1395-16.2016.


Radiation doses and estimated risk from angiographic projections during coronary angiography performed using novel flat detector.

Varghese A, Livingstone RS, Varghese L, Kumar P, Srinath SC, George OK, George PV.

J Appl Clin Med Phys. 2016 May 8;17(3):433-441. doi: 10.1120/jacmp.v17i3.5926.


Unraveling the Mystery Behind A Patient with 'Refractory Seizures'.

Varghese MJ, Lahiri A, Kumar V, Manuel DA, George OK.

J Clin Diagn Res. 2016 Feb;10(2):OD01-2. doi: 10.7860/JCDR/2016/15308.7174. Epub 2016 Feb 1.


T-wave inversions with a difference.

Lahiri A, Alex AG, George OK.

BMJ Case Rep. 2016 Mar 31;2016. pii: bcr2015214307. doi: 10.1136/bcr-2015-214307. No abstract available.


Transcatheter closure of ruptured sinus of valsalva to left ventricle.

Manuel DA, Lahiri A, George OK.

Ann Pediatr Cardiol. 2016 Jan-Apr;9(1):72-4. doi: 10.4103/0974-2069.171386.


A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits.

Pomrenze MB, Millan EZ, Hopf FW, Keiflin R, Maiya R, Blasio A, Dadgar J, Kharazia V, De Guglielmo G, Crawford E, Janak PH, George O, Rice KC, Messing RO.

Front Neurosci. 2015 Dec 24;9:487. doi: 10.3389/fnins.2015.00487. eCollection 2015.


Rate-related hypercoagulable state in mitral stenosis with atrial fibrillation: Can strict rate control prevent thrombus formation?

Panduranga P, Chase D, George O.

Indian Heart J. 2015 Dec;67 Suppl 2:S7-9. doi: 10.1016/j.ihj.2015.07.047. Epub 2015 Nov 10. No abstract available.


Transcatheter closure of direct right pulmonary artery to left atrial communication using vascular plug.

Kumar V, Varghese MJ, George OK.

BMJ Case Rep. 2015 Nov 24;2015. pii: bcr2015212878. doi: 10.1136/bcr-2015-212878.


Pseudoaneurysm following transradial coronary angiogram.

Kumar V, Varghese MJ, Raveendran S, George OK.

Eur Heart J. 2016 Jan 14;37(3):252. doi: 10.1093/eurheartj/ehv425. Epub 2015 Sep 10. No abstract available.


Efficacy of stem cell in improvement of left ventricular function in acute myocardial infarction--MI3 Trial.

Nair V, Madan H, Sofat S, Ganguli P, Jacob MJ, Datta R, Bharadwaj P, Sarkar RS, Pandit AJ, Nityanand S, Goel PK, Garg N, Gambhir S, George PV, Chandy S, Mathews V, George OK, Talwar KK, Bahl A, Marwah N, Bhatacharya A, Bhargava B, Airan B, Mohanty S, Patel CD, Sharma A, Bhatnagar S, Mondal A, Jose J, Srivastava A; MI3 Trial.

Indian J Med Res. 2015 Aug;142(2):165-74. doi: 10.4103/0971-5916.164245.


Smoked out!

Varghese MJ, George OK.

Eur Heart J. 2016 Mar 14;37(11):918. doi: 10.1093/eurheartj/ehv362. Epub 2015 Aug 10. No abstract available.


Transition from image intensifier to flat panel detector in interventional cardiology: Impact of radiation dose.

Livingstone RS, Chase D, Varghese A, George PV, George OK.

J Med Phys. 2015 Jan-Mar;40(1):24-8. doi: 10.4103/0971-6203.152241.

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