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Items: 1 to 50 of 54

1.

Total Synthesis of Rhodonoids A, B, E, and F, Enabled by Singlet Oxygen Ene Reactions.

Burchill L, George JH.

J Org Chem. 2020 Feb 21;85(4):2260-2265. doi: 10.1021/acs.joc.9b02968. Epub 2020 Jan 17.

PMID:
31898902
2.

Biomimetic Synthetic Studies on the Bruceol Family of Meroterpenoid Natural Products.

Day AJ, Sumby CJ, George JH.

J Org Chem. 2020 Feb 21;85(4):2103-2117. doi: 10.1021/acs.joc.9b02862. Epub 2020 Jan 6.

PMID:
31849214
3.

Biomimetic Synthesis Enables the Structure Revision of Furoerioaustralasine.

Coleman MA, Burchill L, Sumby CJ, George JH.

Org Lett. 2019 Nov 1;21(21):8776-8778. doi: 10.1021/acs.orglett.9b03392. Epub 2019 Oct 11.

PMID:
31603336
4.

ortho-Quinone Methide Cyclizations Inspired by the Busseihydroquinone Family of Natural Products.

Burchill L, Pepper HP, Sumby CJ, George JH.

Org Lett. 2019 Oct 18;21(20):8304-8307. doi: 10.1021/acs.orglett.9b03060. Epub 2019 Oct 8.

PMID:
31593469
5.

Total Synthesis of Naphterpin and Marinone Natural Products.

Murray LAM, Fallon T, Sumby CJ, George JH.

Org Lett. 2019 Oct 18;21(20):8312-8315. doi: 10.1021/acs.orglett.9b03095. Epub 2019 Sep 24.

PMID:
31549845
6.

Biomimetic synthetic studies on meroterpenoids from the marine sponge Aka coralliphaga: Divergent total syntheses of siphonodictyal B, liphagal and corallidictyals A-D.

Kuan KKW, Markwell-Heys AW, Cruickshank MC, Tran DP, Adlington RM, Baldwin JE, George JH.

Bioorg Med Chem. 2019 Jun 15;27(12):2449-2465. doi: 10.1016/j.bmc.2019.02.038. Epub 2019 Feb 19.

PMID:
30992205
7.

Ion current and action potential alterations in peripheral neurons subject to uniaxial strain.

Bianchi F, Malboubi M, George JH, Jerusalem A, Thompson MS, Ye H.

J Neurosci Res. 2019 Jul;97(7):744-751. doi: 10.1002/jnr.24408. Epub 2019 Mar 30.

8.

Engineering a uniaxial substrate-stretching device for simultaneous electrophysiological measurements and imaging of strained peripheral neurons.

Bianchi F, George JH, Malboubi M, Jerusalem A, Thompson MS, Ye H.

Med Eng Phys. 2019 May;67:1-10. doi: 10.1016/j.medengphy.2019.02.014. Epub 2019 Mar 14.

9.

Membrane Mechanical Properties Regulate the Effect of Strain on Spontaneous Electrophysiology in Human iPSC-Derived Neurons.

Bianchi F, Pereno V, George JH, Thompson MS, Ye H.

Neuroscience. 2019 Apr 15;404:165-174. doi: 10.1016/j.neuroscience.2019.02.014. Epub 2019 Feb 26.

10.

Visible-Light Photoredox Catalysis Enables the Biomimetic Synthesis of Nyingchinoids A, B, and D, and Rasumatranin D.

Hart JD, Burchill L, Day AJ, Newton CG, Sumby CJ, Huang DM, George JH.

Angew Chem Int Ed Engl. 2019 Feb 25;58(9):2791-2794. doi: 10.1002/anie.201814089. Epub 2019 Feb 4.

PMID:
30648330
11.

Optogenetic control of iPS cell-derived neurons in 2D and 3D culture systems using channelrhodopsin-2 expression driven by the synapsin-1 and calcium-calmodulin kinase II promoters.

Lee SY, George JH, Nagel DA, Ye H, Kueberuwa G, Seymour LW.

J Tissue Eng Regen Med. 2019 Mar;13(3):369-384. doi: 10.1002/term.2786. Epub 2019 Jan 30.

12.

Biomimetic and Biocatalytic Synthesis of Bruceol.

Day AJ, Lee JHZ, Phan QD, Lam HC, Ametovski A, Sumby CJ, Bell SG, George JH.

Angew Chem Int Ed Engl. 2019 Jan 28;58(5):1427-1431. doi: 10.1002/anie.201812432. Epub 2018 Dec 28.

PMID:
30548759
13.

Total Enzyme Syntheses of Napyradiomycins A1 and B1.

McKinnie SMK, Miles ZD, Jordan PA, Awakawa T, Pepper HP, Murray LAM, George JH, Moore BS.

J Am Chem Soc. 2018 Dec 26;140(51):17840-17845. doi: 10.1021/jacs.8b10134. Epub 2018 Dec 14.

14.

A closer look at neuron interaction with track-etched microporous membranes.

George JH, Nagel D, Waller S, Hill E, Parri HR, Coleman MD, Cui Z, Ye H.

Sci Rep. 2018 Oct 19;8(1):15552. doi: 10.1038/s41598-018-33710-6.

15.

Rapid and efficient differentiation of functional motor neurons from human iPSC for neural injury modelling.

Bianchi F, Malboubi M, Li Y, George JH, Jerusalem A, Szele F, Thompson MS, Ye H.

Stem Cell Res. 2018 Oct;32:126-134. doi: 10.1016/j.scr.2018.09.006. Epub 2018 Sep 26.

16.

Total Synthesis Establishes the Biosynthetic Pathway to the Naphterpin and Marinone Natural Products.

Murray LAM, McKinnie SMK, Pepper HP, Erni R, Miles ZD, Cruickshank MC, López-Pérez B, Moore BS, George JH.

Angew Chem Int Ed Engl. 2018 Aug 20;57(34):11009-11014. doi: 10.1002/anie.201804351. Epub 2018 Jul 23.

17.

Aligned electrospun fibers for neural patterning.

Soliman E, Bianchi F, Sleigh JN, George JH, Cader MZ, Cui Z, Ye H.

Biotechnol Lett. 2018 Mar;40(3):601-607. doi: 10.1007/s10529-017-2494-z. Epub 2018 Jan 8.

18.

Engineered method for directional growth of muscle sheets on electrospun fibers.

Soliman E, Bianchi F, Sleigh JN, George JH, Cader MZ, Cui Z, Ye H.

J Biomed Mater Res A. 2018 May;106(5):1165-1176. doi: 10.1002/jbm.a.36312. Epub 2018 Jan 9.

PMID:
29266766
19.

A unifying paradigm for naphthoquinone-based meroterpenoid (bio)synthesis.

Miles ZD, Diethelm S, Pepper HP, Huang DM, George JH, Moore BS.

Nat Chem. 2017 Dec;9(12):1235-1242. doi: 10.1038/nchem.2829. Epub 2017 Jul 31.

20.

Biosynthetically Guided Structure-Activity Relationship Studies of Merochlorin A, an Antibiotic Marine Natural Product.

López-Pérez B, Pepper HP, Ma R, Fawcett BJ, Pehere AD, Wei Q, Ji Z, Polyak SW, Dai H, Song F, Abell AD, Zhang L, George JH.

ChemMedChem. 2017 Dec 7;12(23):1969-1976. doi: 10.1002/cmdc.201700451. Epub 2017 Nov 23.

PMID:
29168322
21.

Biosynthetically-inspired oxidations of capillobenzopyranol.

Pepper HP, Lam HC, George JH.

Org Biomol Chem. 2017 Jun 7;15(22):4811-4815. doi: 10.1039/c7ob00868f.

PMID:
28534902
22.

Biomimetic Total Synthesis of Rhodonoids C and D, and Murrayakonine D.

Day AJ, Lam HC, Sumby CJ, George JH.

Org Lett. 2017 May 19;19(10):2463-2465. doi: 10.1021/acs.orglett.7b00779. Epub 2017 May 3.

PMID:
28467093
23.

Biomimetic Total Synthesis of (±)-Verrubenzospirolactone.

Lam HC, Pepper HP, Sumby CJ, George JH.

Angew Chem Int Ed Engl. 2017 Jul 10;56(29):8532-8535. doi: 10.1002/anie.201700114. Epub 2017 Feb 22.

PMID:
28225178
24.

Biomimetic Total Synthesis of Hyperjapones A-E and Hyperjaponols A and C.

Lam HC, Spence JT, George JH.

Angew Chem Int Ed Engl. 2016 Aug 22;55(35):10368-71. doi: 10.1002/anie.201606091. Epub 2016 Jul 27.

PMID:
27461748
25.

A mechanistic study on the inhibition of α-chymotrypsin by a macrocyclic peptidomimetic aldehyde.

Zhang X, Bruning JB, George JH, Abell AD.

Org Biomol Chem. 2016 Aug 7;14(29):6970-8. doi: 10.1039/c6ob01159d. Epub 2016 Jun 28.

PMID:
27349772
26.

Some chemical speculation on the biosynthesis of corallidictyals A-D.

Markwell-Heys AW, George JH.

Org Biomol Chem. 2016 Jun 28;14(24):5546-9. doi: 10.1039/c6ob00171h. Epub 2016 Feb 22.

PMID:
26899804
27.

Total Synthesis of Peniphenones A-D via Biomimetic Reactions of a Common o-Quinone Methide Intermediate.

Spence JT, George JH.

Org Lett. 2015 Dec 18;17(24):5970-3. doi: 10.1021/acs.orglett.5b02902. Epub 2015 Dec 4.

PMID:
26634635
28.

Total Synthesis and Structure Revision of (-)-Siphonodictyal B and Its Biomimetic Conversion into (+)-Liphagal.

Markwell-Heys AW, Kuan KK, George JH.

Org Lett. 2015 Sep 4;17(17):4228-31. doi: 10.1021/acs.orglett.5b01973. Epub 2015 Aug 21.

PMID:
26295981
29.

Biomimetic total synthesis of (±)-yezo'otogirin A.

Lam HC, Kuan KK, George JH.

Org Biomol Chem. 2014 Apr 28;12(16):2519-22. doi: 10.1039/c4ob00186a.

PMID:
24619430
30.

Selective aliphatic carbon-hydrogen bond activation of protected alcohol substrates by cytochrome P450 enzymes.

Bell SG, Spence JT, Liu S, George JH, Wong LL.

Org Biomol Chem. 2014 Apr 21;12(15):2479-88. doi: 10.1039/c3ob42417k.

PMID:
24599100
31.

Biomimetic total synthesis of (±)-doitunggarcinone A and (+)-garcibracteatone.

Pepper HP, Tulip SJ, Nakano Y, George JH.

J Org Chem. 2014 Mar 21;79(6):2564-73. doi: 10.1021/jo500027k. Epub 2014 Feb 27.

PMID:
24575789
32.

Biomimetic total synthesis of (±)-merochlorin A.

Pepper HP, George JH.

Angew Chem Int Ed Engl. 2013 Nov 11;52(46):12170-3. doi: 10.1002/anie.201307200. Epub 2013 Sep 23. No abstract available.

PMID:
24115251
33.

Biomimetic total synthesis of ent-penilactone A and penilactone B.

Spence JT, George JH.

Org Lett. 2013 Aug 2;15(15):3891-3. doi: 10.1021/ol4017832. Epub 2013 Jul 9.

PMID:
23837511
34.

Biomimetic total synthesis of (±)-garcibracteatone.

Pepper HP, Lam HC, Bloch WM, George JH.

Org Lett. 2012 Oct 5;14(19):5162-4. doi: 10.1021/ol302524q. Epub 2012 Sep 26.

PMID:
23013382
35.

Total synthesis of (+)-aureol.

Kuan KK, Pepper HP, Bloch WM, George JH.

Org Lett. 2012 Sep 21;14(18):4710-3. Epub 2012 Sep 4.

PMID:
22946620
36.

Synthesis of a liphagal-frondosin C hybrid and speculation on the biosynthesis of the frondosins.

Pepper HP, Kuan KK, George JH.

Org Lett. 2012 Mar 16;14(6):1524-7. doi: 10.1021/ol300257v. Epub 2012 Feb 24.

PMID:
22360673
37.

Structural reassignment of cytosporolides A-C via biomimetic synthetic studies and reinterpretation of NMR data.

Spence JT, George JH.

Org Lett. 2011 Oct 7;13(19):5318-21. doi: 10.1021/ol202181g. Epub 2011 Sep 2.

PMID:
21888334
38.

Biomimetic synthesis of polycyclic polyprenylated acylphloroglucinol natural products isolated from Hypericum papuanum.

George JH, Hesse MD, Baldwin JE, Adlington RM.

Org Lett. 2010 Aug 6;12(15):3532-5. doi: 10.1021/ol101380a.

PMID:
20590087
39.

Enantiospecific, biosynthetically inspired formal total synthesis of (+)-liphagal.

George JH, Baldwin JE, Adlington RM.

Org Lett. 2010 May 21;12(10):2394-7. doi: 10.1021/ol100756z.

PMID:
20394432
40.

Synthetic polymer scaffolds for tissue engineering.

Place ES, George JH, Williams CK, Stevens MM.

Chem Soc Rev. 2009 Apr;38(4):1139-51. doi: 10.1039/b811392k. Epub 2009 Feb 16. Review.

PMID:
19421585
41.

Total synthesis of (+)-azinothricin and (+)-kettapeptin.

Hale KJ, Manaviazar S, George JH, Walters MA, Dalby SM.

Org Lett. 2009 Feb 5;11(3):733-6. doi: 10.1021/ol802817t.

PMID:
19175351
42.

Pharmacological actions of a new synthetic cyclodepsipeptide, the A83586C-citropeptin hybrid, on complement C5a and G-Proteins.

Assem ES, Peh KH, Wan BY, Manaviazar S, Walters MA, George JH, Hale KJ.

Inflamm Res. 2008;57 Suppl 1:S21-2. doi: 10.1007/s00011-007-0610-6. No abstract available.

PMID:
18345507
43.

Novel materials for bone and cartilage regeneration.

Bonzani IC, George JH, Stevens MM.

Curr Opin Chem Biol. 2006 Dec;10(6):568-75. Epub 2006 Sep 29. Review.

PMID:
17011226
44.

Empowering junior faculty: Penn State's faculty development and mentoring program.

Thorndyke LE, Gusic ME, George JH, Quillen DA, Milner RJ.

Acad Med. 2006 Jul;81(7):668-73.

PMID:
16799296
45.

Exploring and engineering the cell surface interface.

Stevens MM, George JH.

Science. 2005 Nov 18;310(5751):1135-8. Review.

PMID:
16293749
46.

Enhancing doctor-patient communication using email: a pilot study.

Leong SL, Gingrich D, Lewis PR, Mauger DT, George JH.

J Am Board Fam Pract. 2005 May-Jun;18(3):180-8.

47.

The Epstein-Barr virus encoded latent membrane protein 2A augments signaling from latent membrane protein 1.

Dawson CW, George JH, Blake SM, Longnecker R, Young LS.

Virology. 2001 Oct 25;289(2):192-207.

48.

A simple five-step method for teaching clinical skills.

George JH, Doto FX.

Fam Med. 2001 Sep;33(8):577-8. No abstract available.

PMID:
11573712
49.

What do young adolescent New Zealanders eat? Nutrient intakes of a nationwide sample of form 1 children.

George JH, Brinsdon SC, Paulin JM, Aitken EF.

N Z Med J. 1993 Feb 24;106(950):47-51.

PMID:
8437758
50.

Geometrical aspects of sorted patterned ground in recurrently frozen soil.

Gleason KJ, Krantz WB, Caine N, George JH, Gunn RD.

Science. 1986 Apr 11;232(4747):216-20.

PMID:
17780807

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