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Items: 21

1.

The landscape of somatic mutation in normal colorectal epithelial cells.

Lee-Six H, Olafsson S, Ellis P, Osborne RJ, Sanders MA, Moore L, Georgakopoulos N, Torrente F, Noorani A, Goddard M, Robinson P, Coorens THH, O'Neill L, Alder C, Wang J, Fitzgerald RC, Zilbauer M, Coleman N, Saeb-Parsy K, Martincorena I, Campbell PJ, Stratton MR.

Nature. 2019 Oct;574(7779):532-537. doi: 10.1038/s41586-019-1672-7. Epub 2019 Oct 23.

PMID:
31645730
2.

An Adult Patient with Early Pre-B Acute Lymphoblastic Leukemia with t(12;17)(p13;q21)/ZNF384-TAF15.

Georgakopoulos N, Diamantopoulos P, Micci F, Giannakopoulou N, Zervakis K, Dimitrakopoulou A, Viniou NA.

In Vivo. 2018 Sep-Oct;32(5):1241-1245. doi: 10.21873/invivo.11371. Review.

3.

The mycosporine-like amino acids porphyra-334 and shinorine are antioxidants and direct antagonists of Keap1-Nrf2 binding.

Gacesa R, Lawrence KP, Georgakopoulos ND, Yabe K, Dunlap WC, Barlow DJ, Wells G, Young AR, Long PF.

Biochimie. 2018 Nov;154:35-44. doi: 10.1016/j.biochi.2018.07.020. Epub 2018 Jul 30.

4.

Modified Peptide Inhibitors of the Keap1-Nrf2 Protein-Protein Interaction Incorporating Unnatural Amino Acids.

Georgakopoulos ND, Talapatra SK, Gatliff J, Kozielski F, Wells G.

Chembiochem. 2018 Sep 4;19(17):1810-1816. doi: 10.1002/cbic.201800170. Epub 2018 Jul 18.

5.

Human primary liver cancer-derived organoid cultures for disease modeling and drug screening.

Broutier L, Mastrogiovanni G, Verstegen MM, Francies HE, Gavarró LM, Bradshaw CR, Allen GE, Arnes-Benito R, Sidorova O, Gaspersz MP, Georgakopoulos N, Koo BK, Dietmann S, Davies SE, Praseedom RK, Lieshout R, IJzermans JNM, Wigmore SJ, Saeb-Parsy K, Garnett MJ, van der Laan LJ, Huch M.

Nat Med. 2017 Dec;23(12):1424-1435. doi: 10.1038/nm.4438. Epub 2017 Nov 13.

6.

Reversible Keap1 inhibitors are preferential pharmacological tools to modulate cellular mitophagy.

Georgakopoulos ND, Frison M, Alvarez MS, Bertrand H, Wells G, Campanella M.

Sci Rep. 2017 Sep 4;7(1):10303. doi: 10.1038/s41598-017-07679-7.

7.

Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids.

Sampaziotis F, Justin AW, Tysoe OC, Sawiak S, Godfrey EM, Upponi SS, Gieseck RL 3rd, de Brito MC, Berntsen NL, Gómez-Vázquez MJ, Ortmann D, Yiangou L, Ross A, Bargehr J, Bertero A, Zonneveld MCF, Pedersen MT, Pawlowski M, Valestrand L, Madrigal P, Georgakopoulos N, Pirmadjid N, Skeldon GM, Casey J, Shu W, Materek PM, Snijders KE, Brown SE, Rimland CA, Simonic I, Davies SE, Jensen KB, Zilbauer M, Gelson WTH, Alexander GJ, Sinha S, Hannan NRF, Wynn TA, Karlsen TH, Melum E, Markaki AE, Saeb-Parsy K, Vallier L.

Nat Med. 2017 Aug;23(8):954-963. doi: 10.1038/nm.4360. Epub 2017 Jul 3.

8.

Discovery of the first dual GSK3β inhibitor/Nrf2 inducer. A new multitarget therapeutic strategy for Alzheimer's disease.

Gameiro I, Michalska P, Tenti G, Cores Á, Buendia I, Rojo AI, Georgakopoulos ND, Hernández-Guijo JM, Teresa Ramos M, Wells G, López MG, Cuadrado A, Menéndez JC, León R.

Sci Rep. 2017 Mar 31;7:45701. doi: 10.1038/srep45701.

9.

The pharmacological regulation of cellular mitophagy.

Georgakopoulos ND, Wells G, Campanella M.

Nat Chem Biol. 2017 Jan 19;13(2):136-146. doi: 10.1038/nchembio.2287. Review.

PMID:
28103219
10.

Design, Synthesis, and Evaluation of Triazole Derivatives That Induce Nrf2 Dependent Gene Products and Inhibit the Keap1-Nrf2 Protein-Protein Interaction.

Bertrand HC, Schaap M, Baird L, Georgakopoulos ND, Fowkes A, Thiollier C, Kachi H, Dinkova-Kostova AT, Wells G.

J Med Chem. 2015 Sep 24;58(18):7186-94. doi: 10.1021/acs.jmedchem.5b00602.

PMID:
26348784
11.

PMI: a ΔΨm independent pharmacological regulator of mitophagy.

East DA, Fagiani F, Crosby J, Georgakopoulos ND, Bertrand H, Schaap M, Fowkes A, Wells G, Campanella M.

Chem Biol. 2014 Nov 20;21(11):1585-96. doi: 10.1016/j.chembiol.2014.09.019.

12.

Conservative treatment of closed subtalar dislocation: a case report and 2 years follow-up.

Gantsos A, Giotis D, Giannoulis DK, Vasiliadis HS, Georgakopoulos N, Mitsionis GI.

Foot (Edinb). 2013 Jun-Sep;23(2-3):107-10. doi: 10.1016/j.foot.2013.06.001. Epub 2013 Jul 27.

PMID:
23896287
13.

Traumatic pneumorrhachis: etiology, pathomechanism, diagnosis, and treatment.

Gelalis ID, Karageorgos A, Arnaoutoglou C, Gartzonikas D, Politis A, Georgakopoulos N, Petsanas AP, Matzaroglou C, Xenakis T.

Spine J. 2011 Feb;11(2):153-7. doi: 10.1016/j.spinee.2010.12.010. Review.

PMID:
21296300
14.

Acute apenditis in patient with acute promyelocytic leukemia.

Papageorgiou SG, Foukas P, Economopoulou C, Tsirigotis P, Sakorafas G, Georgakopoulos N, Kefala M, Pappa V, Economopoulos T, Panayiotides I, Papageorgiou E, Dervenoulas J.

Leuk Res. 2011 Jan;35(1):e4-5. doi: 10.1016/j.leukres.2010.08.015. Epub 2010 Sep 19. No abstract available.

PMID:
20855112
15.

Traumatic periprosthetic acetabular fracture treated by acute one-stage revision arthroplasty. A case report and review of the literature.

Gelalis ID, Politis AN, Arnaoutoglou CM, Georgakopoulos N, Mitsiou D, Xenakis TA.

Injury. 2010 Apr;41(4):421-4. doi: 10.1016/j.injury.2009.10.005. Epub 2009 Nov 5. Review. No abstract available.

PMID:
19896125
16.

Electrical therapy in patients with congestive heart failure introduction.

Blanck Z, Georgakopoulos ND, Berger M, Cooley R, Dhala A, Sra J, Deshpande S, Akhtar M.

Curr Probl Cardiol. 2002 Feb;27(2):45-93. Review. No abstract available.

PMID:
11893983
17.

Correlation of spontaneous and induced premature atrial complexes initiating atrial fibrillation in humans: electrophysiologic parameters for guiding therapy.

Sra J, Zaidi ST, Krum D, Georgakopoulos N, Ahmad A, Akhtar M.

J Cardiovasc Electrophysiol. 2001 Dec;12(12):1347-52.

PMID:
11797990
18.

Left ventricular function during interval and steady state exercise.

Foster C, Meyer K, Georgakopoulos N, Ellestad AJ, Fitzgerald DJ, Tilman K, Weinstein H, Young H, Roskamm H.

Med Sci Sports Exerc. 1999 Aug;31(8):1157-62.

PMID:
10449018
19.

Comparison of left ventricular function during interval versus steady-state exercise training in patients with chronic congestive heart failure.

Meyer K, Foster C, Georgakopoulos N, Hajric R, Westbrook S, Ellestad A, Tilman K, Fitzgerald D, Young H, Weinstein H, Roskamm H.

Am J Cardiol. 1998 Dec 1;82(11):1382-7.

PMID:
9856924
20.

Physiological and pathological aspects of exercise left ventricular function.

Foster C, Georgakopoulos N, Meyer K.

Med Sci Sports Exerc. 1998 Oct;30(10 Suppl):S379-86. Review.

PMID:
9789864
21.

[Isolation of Chromobacterium prodigiosum in a case of chronic atypical pneumonia].

MICHAEL KP, GEORGAKOPOULOS N.

Delt Hell Mikrobiol Hygieinol Hetair. 1961 Sep-Dec;6:144-9. Greek, Modern. No abstract available.

PMID:
14473317

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