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Items: 18


High-throughput Screening of Human Tumor Antigen-specific CD4 T Cells, Including Neoantigen-reactive T Cells.

Costa-Nunes C, Cachot A, Bobisse S, Arnaud M, Genolet R, Baumgaertner P, Speiser DE, Sousa Alves PM, Sandoval F, Adotévi O, Reith W, Protti MP, Coukos G, Harari A, Romero P, Jandus C.

Clin Cancer Res. 2019 Apr 23. doi: 10.1158/1078-0432.CCR-18-1356. [Epub ahead of print]


Computational KIR copy number discovery reveals interaction between inhibitory receptor burden and survival.

Pyke RM, Genolet R, Harari A, Coukos G, Gfeller D, Carter H.

Pac Symp Biocomput. 2019;24:148-159.


Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer.

Tanyi JL, Bobisse S, Ophir E, Tuyaerts S, Roberti A, Genolet R, Baumgartner P, Stevenson BJ, Iseli C, Dangaj D, Czerniecki B, Semilietof A, Racle J, Michel A, Xenarios I, Chiang C, Monos DS, Torigian DA, Nisenbaum HL, Michielin O, June CH, Levine BL, Powell DJ Jr, Gfeller D, Mick R, Dafni U, Zoete V, Harari A, Coukos G, Kandalaft LE.

Sci Transl Med. 2018 Apr 11;10(436). pii: eaao5931. doi: 10.1126/scitranslmed.aao5931.


Sensitive and frequent identification of high avidity neo-epitope specific CD8 + T cells in immunotherapy-naive ovarian cancer.

Bobisse S, Genolet R, Roberti A, Tanyi JL, Racle J, Stevenson BJ, Iseli C, Michel A, Le Bitoux MA, Guillaume P, Schmidt J, Bianchi V, Dangaj D, Fenwick C, Derré L, Xenarios I, Michielin O, Romero P, Monos DS, Zoete V, Gfeller D, Kandalaft LE, Coukos G, Harari A.

Nat Commun. 2018 Mar 15;9(1):1092. doi: 10.1038/s41467-018-03301-0.


Label-free identification of activated T lymphocytes through tridimensional microsensors on chip.

Rollo E, Tenaglia E, Genolet R, Bianchi E, Harari A, Coukos G, Guiducci C.

Biosens Bioelectron. 2017 Aug 15;94:193-199. doi: 10.1016/j.bios.2017.02.047. Epub 2017 Mar 3.


Duality of the murine CD8 compartment.

Genolet R, Leignadier J, Østerås M, Farinelli L, Stevenson BJ, Luescher IF.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):E1007-15. doi: 10.1073/pnas.1317847111. Epub 2014 Mar 4.


CTLA-4 controls the thymic development of both conventional and regulatory T cells through modulation of the TCR repertoire.

Verhagen J, Genolet R, Britton GJ, Stevenson BJ, Sabatos-Peyton CA, Dyson J, Luescher IF, Wraith DC.

Proc Natl Acad Sci U S A. 2013 Jan 15;110(3):E221-30. doi: 10.1073/pnas.1208573110. Epub 2012 Dec 24.


Highly diverse TCRα chain repertoire of pre-immune CD8⁺ T cells reveals new insights in gene recombination.

Genolet R, Stevenson BJ, Farinelli L, Osterås M, Luescher IF.

EMBO J. 2012 Nov 5;31(21):4247-8. doi: 10.1038/emboj.2012.277. No abstract available.


The T-cell receptor is not hardwired to engage MHC ligands.

Holland SJ, Bartok I, Attaf M, Genolet R, Luescher IF, Kotsiou E, Richard A, Wang E, White M, Coe DJ, Chai JG, Ferreira C, Dyson J.

Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):E3111-8. doi: 10.1073/pnas.1210882109. Epub 2012 Oct 17.


KAP1 regulates gene networks controlling T-cell development and responsiveness.

Santoni de Sio FR, Barde I, Offner S, Kapopoulou A, Corsinotti A, Bojkowska K, Genolet R, Thomas JH, Luescher IF, Pinschewer D, Harris N, Trono D.

FASEB J. 2012 Nov;26(11):4561-75. doi: 10.1096/fj.12-206177. Epub 2012 Aug 7.


Highly diverse TCRα chain repertoire of pre-immune CD8⁺ T cells reveals new insights in gene recombination.

Genolet R, Stevenson BJ, Farinelli L, Osterås M, Luescher IF.

EMBO J. 2012 Apr 4;31(7):1666-78. doi: 10.1038/emboj.2012.48. Epub 2012 Feb 28.


The translational response of the human mdm2 gene in HEK293T cells exposed to rapamycin: a role for the 5'-UTRs.

Genolet R, Rahim G, Gubler-Jaquier P, Curran J.

Nucleic Acids Res. 2011 Feb;39(3):989-1003. doi: 10.1093/nar/gkq805. Epub 2010 Sep 28.


Definition of key variables for the induction of optimal NY-ESO-1-specific T cells in HLA transgene mice.

Johannsen A, Genolet R, Legler DF, Luther SA, Luescher IF.

J Immunol. 2010 Sep 15;185(6):3445-55. doi: 10.4049/jimmunol.1001397. Epub 2010 Aug 23.


Transcriptional and post-transcriptional profile of human chromosome 21.

Nikolaev SI, Deutsch S, Genolet R, Borel C, Parand L, Ucla C, Schütz F, Duriaux Sail G, Dupré Y, Jaquier-Gubler P, Araud T, Conne B, Descombes P, Vassalli JD, Curran J, Antonarakis SE.

Genome Res. 2009 Aug;19(8):1471-9. doi: 10.1101/gr.089425.108. Epub 2009 Jul 6.


An approach to analyse the specific impact of rapamycin on mRNA-ribosome association.

Genolet R, Araud T, Maillard L, Jaquier-Gubler P, Curran J.

BMC Med Genomics. 2008 Aug 1;1:33. doi: 10.1186/1755-8794-1-33.


Alternatively spliced isoforms of the human elk-1 mRNA within the 5' UTR: implications for ELK-1 expression.

Araud T, Genolet R, Jaquier-Gubler P, Curran J.

Nucleic Acids Res. 2007;35(14):4649-63. Epub 2007 Jun 25.


Promoter rearrangements cause species-specific hepatic regulation of the glyoxylate reductase/hydroxypyruvate reductase gene by the peroxisome proliferator-activated receptor alpha.

Genolet R, Kersten S, Braissant O, Mandard S, Tan NS, Bucher P, Desvergne B, Michalik L, Wahli W.

J Biol Chem. 2005 Jun 24;280(25):24143-52. Epub 2005 Apr 19.


PPARs as drug targets to modulate inflammatory responses?

Genolet R, Wahli W, Michalik L.

Curr Drug Targets Inflamm Allergy. 2004 Dec;3(4):361-75. Review.


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