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Items: 12

1.

Ficolin-2 binds to serotype 35B pneumococcus as it does to serotypes 11A and 31, and these serotypes cause more infections in older adults than in children.

Geno KA, Spencer BL, Bae S, Nahm MH.

PLoS One. 2018 Dec 26;13(12):e0209657. doi: 10.1371/journal.pone.0209657. eCollection 2018.

2.

WciG O-Acetyltransferase Functionality Differentiates Pneumococcal Serotypes 35C and 42.

Geno KA, Bush CA, Wang M, Jin C, Nahm MH, Yang J.

J Clin Microbiol. 2017 Sep;55(9):2775-2784. doi: 10.1128/JCM.00822-17. Epub 2017 Jun 28.

3.

Discovery of Novel Pneumococcal Serotype 35D, a Natural WciG-Deficient Variant of Serotype 35B.

Geno KA, Saad JS, Nahm MH.

J Clin Microbiol. 2017 May;55(5):1416-1425. doi: 10.1128/JCM.00054-17. Epub 2017 Feb 15.

4.

Ficolin-2 inhibitors are present in sera after prolonged storage at -80 °C.

Geno KA, Kennedy RE, Sawyer P, Brown CJ, Nahm MH.

PeerJ. 2016 Nov 17;4:e2705. eCollection 2016.

5.

Pneumococcus with the "6E" cps Locus Produces Serotype 6B Capsular Polysaccharide.

Burton RL, Geno KA, Saad JS, Nahm MH.

J Clin Microbiol. 2016 Apr;54(4):967-71. doi: 10.1128/JCM.03194-15. Epub 2016 Jan 27.

6.

Pneumococcal Capsules and Their Types: Past, Present, and Future.

Geno KA, Gilbert GL, Song JY, Skovsted IC, Klugman KP, Jones C, Konradsen HB, Nahm MH.

Clin Microbiol Rev. 2015 Jul;28(3):871-99. doi: 10.1128/CMR.00024-15. Review.

7.

Rapid and efficient purification of ficolin-2 using a disposable CELLine bioreactor.

Geno KA, Spencer BL, Nahm MH.

J Immunol Methods. 2015 Sep;424:106-10. doi: 10.1016/j.jim.2015.05.008. Epub 2015 May 30.

8.

Genetic, biochemical, and serological characterization of a new pneumococcal serotype, 6H, and generation of a pneumococcal strain producing three different capsular repeat units.

Park IH, Geno KA, Yu J, Oliver MB, Kim KH, Nahm MH.

Clin Vaccine Immunol. 2015 Mar;22(3):313-8. doi: 10.1128/CVI.00647-14. Epub 2015 Jan 14.

9.

Commercially available complement component-depleted sera are unexpectedly codepleted of ficolin-2.

Brady AM, Geno KA, Dalecki AG, Cheng X, Nahm MH.

Clin Vaccine Immunol. 2014 Sep;21(9):1323-9. doi: 10.1128/CVI.00370-14. Epub 2014 Jul 16.

10.

Population-based analysis of invasive nontypeable pneumococci reveals that most have defective capsule synthesis genes.

Park IH, Geno KA, Sherwood LK, Nahm MH, Beall B.

PLoS One. 2014 May 15;9(5):e97825. doi: 10.1371/journal.pone.0097825. eCollection 2014.

11.

Low invasiveness of pneumococcal serotype 11A is linked to ficolin-2 recognition of O-acetylated capsule epitopes and lectin complement pathway activation.

Brady AM, Calix JJ, Yu J, Geno KA, Cutter GR, Nahm MH.

J Infect Dis. 2014 Oct 1;210(7):1155-65. doi: 10.1093/infdis/jiu195. Epub 2014 Mar 27.

12.

Streptococcus pneumoniae phosphotyrosine phosphatase CpsB and alterations in capsule production resulting from changes in oxygen availability.

Geno KA, Hauser JR, Gupta K, Yother J.

J Bacteriol. 2014 Jun;196(11):1992-2003. doi: 10.1128/JB.01545-14. Epub 2014 Mar 21.

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