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A Novel Approach to Chemical Mixture Risk Assessment-Linking Data from Population-Based Epidemiology and Experimental Animal Tests.

Bornehag CG, Kitraki E, Stamatakis A, Panagiotidou E, Rudén C, Shu H, Lindh C, Ruegg J, Gennings C.

Risk Anal. 2019 Jun 7. doi: 10.1111/risa.13323. [Epub ahead of print]


Gestational exposure to an epidemiologically defined mixture of phthalates leads to gonadal dysfunction in mouse offspring of both sexes.

Repouskou A, Panagiotidou E, Panagopoulou L, Bisting PL, Tuck AR, Sjödin MOD, Lindberg J, Bozas E, Rüegg J, Gennings C, Bornehag CG, Damdimopoulou P, Stamatakis A, Kitraki E.

Sci Rep. 2019 Apr 23;9(1):6424. doi: 10.1038/s41598-019-42377-6.


In utero metal exposures measured in deciduous teeth and birth outcomes in a racially-diverse urban cohort.

Cassidy-Bushrow AE, Wu KH, Sitarik AR, Park SK, Bielak LF, Austin C, Gennings C, Curtin P, Johnson CC, Arora M.

Environ Res. 2019 Apr;171:444-451. doi: 10.1016/j.envres.2019.01.054. Epub 2019 Jan 31.


Modeling the health effects of time-varying complex environmental mixtures: Mean field variational Bayes for lagged kernel machine regression.

Liu SH, Bobb JF, Claus Henn B, Schnaas L, Tellez-Rojo MM, Gennings C, Arora M, Wright RO, Coull BA, Wand MP.

Environmetrics. 2018 Jun;29(4). pii: e2504. doi: 10.1002/env.2504. Epub 2018 May 18.


Assessing the contributions of metals in environmental media to exposure biomarkers in a region of ferroalloy industry.

Butler L, Gennings C, Peli M, Borgese L, Placidi D, Zimmerman N, Hsu HL, Coull BA, Wright RO, Smith DR, Lucchini RG, Claus Henn B.

J Expo Sci Environ Epidemiol. 2018 Oct 18. doi: 10.1038/s41370-018-0081-6. [Epub ahead of print]


Bayesian varying coefficient kernel machine regression to assess neurodevelopmental trajectories associated with exposure to complex mixtures.

Liu SH, Bobb JF, Claus Henn B, Gennings C, Schnaas L, Tellez-Rojo M, Bellinger D, Arora M, Wright RO, Coull BA.

Stat Med. 2018 Dec 30;37(30):4680-4694. doi: 10.1002/sim.7947. Epub 2018 Sep 12.


Sources of clinically significant neonatal intensive care unit phthalate exposure.

Stroustrup A, Bragg JB, Busgang SA, Andra SS, Curtin P, Spear EA, Just AC, Arora M, Gennings C.

J Expo Sci Environ Epidemiol. 2018 Sep 21. doi: 10.1038/s41370-018-0069-2. [Epub ahead of print]


PVC flooring at home and uptake of phthalates in pregnant women.

Shu H, Jönsson BAG, Gennings C, Lindh CH, Nånberg E, Bornehag CG.

Indoor Air. 2019 Jan;29(1):43-54. doi: 10.1111/ina.12508. Epub 2018 Nov 10.


Dentine biomarkers of prenatal and early childhood exposure to manganese, zinc and lead and childhood behavior.

Horton MK, Hsu L, Claus Henn B, Margolis A, Austin C, Svensson K, Schnaas L, Gennings C, Hu H, Wright R, Rojo MMT, Arora M.

Environ Int. 2018 Dec;121(Pt 1):148-158. doi: 10.1016/j.envint.2018.08.045. Epub 2018 Sep 8.


Incorporating regulatory guideline values in analysis of epidemiology data.

Gennings C, Shu H, Rudén C, Öberg M, Lindh C, Kiviranta H, Bornehag CG.

Environ Int. 2018 Nov;120:535-543. doi: 10.1016/j.envint.2018.08.039. Epub 2018 Aug 28.


Prenatal lead exposure modifies the effect of shorter gestation on increased blood pressure in children.

Sanders AP, Svensson K, Gennings C, Burris HH, Oken E, Amarasiriwardena C, Basnet P, Pizano-Zarate ML, Schnaas L, Tamayo-Ortiz M, Baccarelli AA, Satlin LM, Wright RO, Tellez-Rojo MM.

Environ Int. 2018 Nov;120:464-471. doi: 10.1016/j.envint.2018.08.038. Epub 2018 Aug 23.


Intrauterine multi-metal exposure is associated with reduced fetal growth through modulation of the placental gene network.

Deyssenroth MA, Gennings C, Liu SH, Peng S, Hao K, Lambertini L, Jackson BP, Karagas MR, Marsit CJ, Chen J.

Environ Int. 2018 Nov;120:373-381. doi: 10.1016/j.envint.2018.08.010. Epub 2018 Aug 17.


Quality of Prenatal and Childhood Diet Predicts Neurodevelopmental Outcomes among Children in Mexico City.

Malin AJ, Busgang SA, Cantoral AJ, Svensson K, Orjuela MA, Pantic I, Schnaas L, Oken E, Baccarelli AA, Téllez-Rojo MM, Wright RO, Gennings C.

Nutrients. 2018 Aug 15;10(8). pii: E1093. doi: 10.3390/nu10081093.


Dynamical features in fetal and postnatal zinc-copper metabolic cycles predict the emergence of autism spectrum disorder.

Curtin P, Austin C, Curtin A, Gennings C, Arora M; (for the Emergent Dynamical Systems Group), Tammimies K, Willfors C, Berggren S, Siper P, Rai D, Meyering K, Kolevzon A, Mollon J, David AS, Lewis G, Zammit S, Heilbrun L, Palmer RF, Wright RO, Bölte S, Reichenberg A.

Sci Adv. 2018 May 30;4(5):eaat1293. doi: 10.1126/sciadv.aat1293. eCollection 2018 May.


How similar is similar enough? A sufficient similarity case study with Ginkgo biloba extract.

Catlin NR, Collins BJ, Auerbach SS, Ferguson SS, Harnly JM, Gennings C, Waidyanatha S, Rice GE, Smith-Roe SL, Witt KL, Rider CV.

Food Chem Toxicol. 2018 Aug;118:328-339. doi: 10.1016/j.fct.2018.05.013. Epub 2018 May 9.


Modeling Pediatric Body Mass Index and Neighborhood Environment at Different Spatial Scales.

Grant LP, Gennings C, Wickham EP, Chapman D, Sun S, Wheeler DC.

Int J Environ Res Public Health. 2018 Mar 8;15(3). pii: E473. doi: 10.3390/ijerph15030473.


Neonatal intensive care unit phthalate exposure and preterm infant neurobehavioral performance.

Stroustrup A, Bragg JB, Andra SS, Curtin PC, Spear EA, Sison DB, Just AC, Arora M, Gennings C.

PLoS One. 2018 Mar 5;13(3):e0193835. doi: 10.1371/journal.pone.0193835. eCollection 2018.


Temporal trends of phthalate exposures during 2007-2010 in Swedish pregnant women.

Shu H, Jönsson BA, Gennings C, Svensson Å, Nånberg E, Lindh CH, Knutz M, Takaro TK, Bornehag CG.

J Expo Sci Environ Epidemiol. 2018 Sep;28(5):437-447. doi: 10.1038/s41370-018-0020-6. Epub 2018 Feb 22.


Uncovering neurodevelopmental windows of susceptibility to manganese exposure using dentine microspatial analyses.

Claus Henn B, Austin C, Coull BA, Schnaas L, Gennings C, Horton MK, Hernández-Ávila M, Hu H, Téllez-Rojo MM, Wright RO, Arora M.

Environ Res. 2018 Feb;161:588-598. doi: 10.1016/j.envres.2017.12.003.


Recurrence quantification analysis to characterize cyclical components of environmental elemental exposures during fetal and postnatal development.

Curtin P, Curtin A, Austin C, Gennings C, Tammimies K, Bölte S, Arora M.

PLoS One. 2017 Nov 7;12(11):e0187049. doi: 10.1371/journal.pone.0187049. eCollection 2017.


New Research Strategy for Measuring Pre- and Postnatal Metal Dysregulation in Psychotic Disorders.

Velthorst E, Smith L, Bello G, Austin C, Gennings C, Modabbernia A, Franke N, Frangou S, Wright R, de Haan L, Reichenberg A, Arora M.

Schizophr Bull. 2017 Oct 21;43(6):1153-1157. doi: 10.1093/schbul/sbx112.


Lagged kernel machine regression for identifying time windows of susceptibility to exposures of complex mixtures.

Liu SH, Bobb JF, Lee KH, Gennings C, Claus Henn B, Bellinger D, Austin C, Schnaas L, Tellez-Rojo MM, Hu H, Wright RO, Arora M, Coull BA.

Biostatistics. 2018 Jul 1;19(3):325-341. doi: 10.1093/biostatistics/kxx036.


Corrigendum to "Extending the Distributed Lag Model framework to handle chemical mixtures" [Environ. Res. 156 (2017) 253-264].

Bello GA, Arora M, Austin C, Horton MK, Wright RO, Gennings C.

Environ Res. 2017 Nov;159:650. doi: 10.1016/j.envres.2017.09.001. Epub 2017 Sep 13. No abstract available.


Prenatal Stress, Methylation in Inflammation-Related Genes, and Adiposity Measures in Early Childhood: the Programming Research in Obesity, Growth Environment and Social Stress Cohort Study.

Wu S, Gennings C, Wright RJ, Wilson A, Burris HH, Just AC, Braun JM, Svensson K, Zhong J, Brennan KJM, Dereix A, Cantoral A, Schnaas L, Téllez-Rojo MM, Wright RO, Baccarelli AA.

Psychosom Med. 2018 Jan;80(1):34-41. doi: 10.1097/PSY.0000000000000517.


Prenatal exposure to PM2.5 and birth weight: A pooled analysis from three North American longitudinal pregnancy cohort studies.

Rosa MJ, Pajak A, Just AC, Sheffield PE, Kloog I, Schwartz J, Coull B, Enlow MB, Baccarelli AA, Huddleston K, Niederhuber JE, Rojo MMT, Wright RO, Gennings C, Wright RJ.

Environ Int. 2017 Oct;107:173-180. doi: 10.1016/j.envint.2017.07.012. Epub 2017 Jul 22.


Maternal Lifetime Stress and Prenatal Psychological Functioning and Decreased Placental Mitochondrial DNA Copy Number in the PRISM Study.

Brunst KJ, Sanchez Guerra M, Gennings C, Hacker M, Jara C, Bosquet Enlow M, Wright RO, Baccarelli A, Wright RJ.

Am J Epidemiol. 2017 Dec 1;186(11):1227-1236. doi: 10.1093/aje/kwx183.


Fetal and postnatal metal dysregulation in autism.

Arora M, Reichenberg A, Willfors C, Austin C, Gennings C, Berggren S, Lichtenstein P, Anckarsäter H, Tammimies K, Bölte S.

Nat Commun. 2017 Jun 1;8:15493. doi: 10.1038/ncomms15493.


Extending the Distributed Lag Model framework to handle chemical mixtures.

Bello GA, Arora M, Austin C, Horton MK, Wright RO, Gennings C.

Environ Res. 2017 Jul;156:253-264. doi: 10.1016/j.envres.2017.03.031. Epub 2017 Apr 3. Erratum in: Environ Res. 2017 Nov;159:650.


Big and disparate data: considerations for pediatric consortia.

Stingone JA, Mervish N, Kovatch P, McGuinness DL, Gennings C, Teitelbaum SL.

Curr Opin Pediatr. 2017 Apr;29(2):231-239. doi: 10.1097/MOP.0000000000000467. Review.


Bacterial and cytokine mixtures predict the length of gestation and are associated with miRNA expression in the cervix.

Sanders AP, Gennings C, Svensson K, Motta V, Mercado-Garcia A, Solano M, Baccarelli AA, Tellez-Rojo MM, Wright RO, Burris HH.

Epigenomics. 2017 Jan;9(1):33-45. doi: 10.2217/epi-2016-0095. Epub 2016 Dec 12.


Statistical Approaches for Assessing Health Effects of Environmental Chemical Mixtures in Epidemiology: Lessons from an Innovative Workshop.

Taylor KW, Joubert BR, Braun JM, Dilworth C, Gennings C, Hauser R, Heindel JJ, Rider CV, Webster TF, Carlin DJ.

Environ Health Perspect. 2016 Dec 1;124(12):A227-A229. No abstract available.


Association Between Dietary Intake and Function in Amyotrophic Lateral Sclerosis.

Nieves JW, Gennings C, Factor-Litvak P, Hupf J, Singleton J, Sharf V, Oskarsson B, Fernandes Filho JA, Sorenson EJ, D'Amico E, Goetz R, Mitsumoto H; Amyotrophic Lateral Sclerosis Multicenter Cohort Study of Oxidative Stress (ALS COSMOS) Study Group.

JAMA Neurol. 2016 Dec 1;73(12):1425-1432. doi: 10.1001/jamaneurol.2016.3401.


Manipulation of pre and postnatal androgen environments and anogenital distance in rats.

Kita DH, Meyer KB, Venturelli AC, Adams R, Machado DL, Morais RN, Swan SH, Gennings C, Martino-Andrade AJ.

Toxicology. 2016 Aug 10;368-369:152-161. doi: 10.1016/j.tox.2016.08.021. Epub 2016 Sep 14.


Early-life metal exposure and schizophrenia: A proof-of-concept study using novel tooth-matrix biomarkers.

Modabbernia A, Velthorst E, Gennings C, De Haan L, Austin C, Sutterland A, Mollon J, Frangou S, Wright R, Arora M, Reichenberg A.

Eur Psychiatry. 2016 Aug;36:1-6. doi: 10.1016/j.eurpsy.2016.03.006. Epub 2016 Jun 14.


Effects of an environmentally-relevant mixture of pyrethroid insecticides on spontaneous activity in primary cortical networks on microelectrode arrays.

Johnstone AFM, Strickland JD, Crofton KM, Gennings C, Shafer TJ.

Neurotoxicology. 2017 May;60:234-239. doi: 10.1016/j.neuro.2016.05.005. Epub 2016 May 10.


Telephone based cognitive-behavioral screening for frontotemporal changes in patients with amyotrophic lateral sclerosis (ALS).

Christodoulou G, Gennings C, Hupf J, Factor-Litvak P, Murphy J, Goetz RR, Mitsumoto H.

Amyotroph Lateral Scler Frontotemporal Degener. 2016 Oct - Nov;17(7-8):482-488. Epub 2016 Apr 28.


Phenotypic and molecular analyses of primary lateral sclerosis.

Mitsumoto H, Nagy PL, Gennings C, Murphy J, Andrews H, Goetz R, Floeter MK, Hupf J, Singleton J, Barohn RJ, Nations S, Shoesmith C, Kasarskis E, Factor-Litvak P.

Neurol Genet. 2015 Apr 14;1(1):e3. doi: 10.1212/01.NXG.0000464294.88607.dd. eCollection 2015 Jun.


What Can Epidemiological Studies Tell Us about the Impact of Chemical Mixtures on Human Health?

Braun JM, Gennings C, Hauser R, Webster TF.

Environ Health Perspect. 2016 Jan;124(1):A6-9. doi: 10.1289/ehp.1510569.


Lifetime exposure to traumatic and other stressful life events and hair cortisol in a multi-racial/ethnic sample of pregnant women.

Schreier HM, Enlow MB, Ritz T, Coull BA, Gennings C, Wright RO, Wright RJ.

Stress. 2016;19(1):45-52. doi: 10.3109/10253890.2015.1117447. Epub 2015 Dec 8.


Associations between Prenatal Exposure to Black Carbon and Memory Domains in Urban Children: Modification by Sex and Prenatal Stress.

Cowell WJ, Bellinger DC, Coull BA, Gennings C, Wright RO, Wright RJ.

PLoS One. 2015 Nov 6;10(11):e0142492. doi: 10.1371/journal.pone.0142492. eCollection 2015.


Validation of a Food Frequency Questionnaire for Estimating Micronutrient Intakes in an Urban US Sample of Multi-Ethnic Pregnant Women.

Brunst KJ, Kannan S, Ni YM, Gennings C, Ganguri HB, Wright RJ.

Matern Child Health J. 2016 Feb;20(2):250-60. doi: 10.1007/s10995-015-1824-9.


CO-occurring exposure to perchlorate, nitrate and thiocyanate alters thyroid function in healthy pregnant women.

Horton MK, Blount BC, Valentin-Blasini L, Wapner R, Whyatt R, Gennings C, Factor-Litvak P.

Environ Res. 2015 Nov;143(Pt A):1-9. doi: 10.1016/j.envres.2015.09.013. Epub 2015 Sep 25.


Development and Validation of a Clinical Risk-Assessment Tool Predictive of All-Cause Mortality.

Bello GA, Dumancas GG, Gennings C.

Bioinform Biol Insights. 2015 Sep 1;9(Suppl 3):1-10. doi: 10.4137/BBI.S30172. eCollection 2015.


Childhood abuse is associated with increased hair cortisol levels among urban pregnant women.

Schreier HM, Enlow MB, Ritz T, Gennings C, Wright RJ.

J Epidemiol Community Health. 2015 Dec;69(12):1169-74. doi: 10.1136/jech-2015-205541. Epub 2015 Jul 28.


Assessment of weighted quantile sum regression for modeling chemical mixtures and cancer risk.

Czarnota J, Gennings C, Wheeler DC.

Cancer Inform. 2015 May 13;14(Suppl 2):159-71. doi: 10.4137/CIN.S17295. eCollection 2015.


Evaluating geographically weighted regression models for environmental chemical risk analysis.

Czarnota J, Wheeler DC, Gennings C.

Cancer Inform. 2015 May 5;14(Suppl 2):117-27. doi: 10.4137/CIN.S17296. eCollection 2015.


Selecting spatial scale of covariates in regression models of environmental exposures.

Grant LP, Gennings C, Wheeler DC.

Cancer Inform. 2015 Apr 27;14(Suppl 2):81-96. doi: 10.4137/CIN.S17302. eCollection 2015.


Assessment of phthalates/phthalate alternatives in children's toys and childcare articles: Review of the report including conclusions and recommendation of the Chronic Hazard Advisory Panel of the Consumer Product Safety Commission.

Lioy PJ, Hauser R, Gennings C, Koch HM, Mirkes PE, Schwetz BA, Kortenkamp A.

J Expo Sci Environ Epidemiol. 2015 Jul-Aug;25(4):343-53. doi: 10.1038/jes.2015.33. Epub 2015 May 6. Review.


Analysis of Environmental Chemical Mixtures and Non-Hodgkin Lymphoma Risk in the NCI-SEER NHL Study.

Czarnota J, Gennings C, Colt JS, De Roos AJ, Cerhan JR, Severson RK, Hartge P, Ward MH, Wheeler DC.

Environ Health Perspect. 2015 Oct;123(10):965-70. doi: 10.1289/ehp.1408630. Epub 2015 Mar 6.


Characterization of Weighted Quantile Sum Regression for Highly Correlated Data in a Risk Analysis Setting.

Carrico C, Gennings C, Wheeler DC, Factor-Litvak P.

J Agric Biol Environ Stat. 2015 Mar;20(1):100-120. doi: 10.1007/s13253-014-0180-3. Epub 2014 Dec 24.

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