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Effects of arsenic exposure on D-serine metabolism in the hippocampus of offspring mice at different developmental stages.

Wang Y, Yang X, Yu H, Wang H, Qi Y, Geng M.

Arch Toxicol. 2019 Nov 11. doi: 10.1007/s00204-019-02616-1. [Epub ahead of print]


Short communication: Lactose utilization of Streptococcus thermophilus and correlations with β-galactosidase and urease.

Yu P, Li N, Geng M, Liu Z, Liu X, Zhang H, Zhao J, Zhang H, Chen W.

J Dairy Sci. 2019 Nov 5. pii: S0022-0302(19)30965-8. doi: 10.3168/jds.2019-17009. [Epub ahead of print]


TIPE1 accelerates atherogenesis by inducing endothelial dysfunction in response to oxidative stress.

Shao J, Li Y, Zhou C, Geng M, Zhang G, Zhang N, Jin G, Zhang L, Gao C, Liu S.

Biochim Biophys Acta Mol Basis Dis. 2020 Jan 1;1866(1):165578. doi: 10.1016/j.bbadis.2019.165578. Epub 2019 Oct 28.


Pterostilbene Attenuates Experimental Atherosclerosis through Restoring Catalase-Mediated Redox Balance in Vascular Smooth Muscle Cells.

Wang W, Wang YR, Chen J, Chen YJ, Wang ZX, Geng M, Xu DC, Wang ZY, Li JH, Xu ZD, Pan LL, Sun J.

J Agric Food Chem. 2019 Nov 20;67(46):12752-12760. doi: 10.1021/acs.jafc.9b05373. Epub 2019 Nov 8.


Targeting CDK12-mediated transcription regulation in anaplastic thyroid carcinoma.

Geng M, Yang Y, Cao X, Dang L, Zhang T, Zhang L.

Biochem Biophys Res Commun. 2019 Dec 10;520(3):544-550. doi: 10.1016/j.bbrc.2019.10.052. Epub 2019 Oct 12.


Fat-Specific Knockout of Mecp2 Upregulates Slpi to Reduce Obesity by Enhancing Browning.

Liu C, Wang J, Wei Y, Zhang W, Geng M, Yuan Y, Chen Y, Sun Y, Chen H, Zhang Y, Xiong M, Li Y, Zheng L, Huang K.

Diabetes. 2019 Oct 9. pii: db190502. doi: 10.2337/db19-0502. [Epub ahead of print]


Factors associated with appendicular skeletal muscle mass among male Chinese patients with stable chronic obstructive pulmonary disease: A hospital-based cross-sectional study.

Han Y, Wu Z, Chen Y, Kan Y, Geng M, Xu N, Qian H, Wang HF, Niu M.

Medicine (Baltimore). 2019 Oct;98(40):e17361. doi: 10.1097/MD.0000000000017361.


Automatic Seizure Detection Based on S-Transform and Deep Convolutional Neural Network.

Liu G, Zhou W, Geng M.

Int J Neural Syst. 2019 Sep 30:1950024. doi: 10.1142/S0129065719500242. [Epub ahead of print]


Screening for differential expression of genes for resistance to Sitodiplosis mosellana in bread wheat via BSR-seq analysis.

Hao Z, Geng M, Hao Y, Zhang Y, Zhang L, Wen S, Wang R, Liu G.

Theor Appl Genet. 2019 Nov;132(11):3201-3221. doi: 10.1007/s00122-019-03419-9. Epub 2019 Sep 9.


Target-inspired Pb2+-dependent DNAzyme for ultrasensitive electrochemical sensor based on MoS2-AuPt nanocomposites and hemin/G-quadruplex DNAzyme as signal amplifier.

Ji R, Niu W, Chen S, Xu W, Ji X, Yuan L, Zhao H, Geng M, Qiu J, Li C.

Biosens Bioelectron. 2019 Nov 1;144:111560. doi: 10.1016/j.bios.2019.111560. Epub 2019 Aug 3.


Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease progression.

Wang X, Sun G, Feng T, Zhang J, Huang X, Wang T, Xie Z, Chu X, Yang J, Wang H, Chang S, Gong Y, Ruan L, Zhang G, Yan S, Lian W, Du C, Yang D, Zhang Q, Lin F, Liu J, Zhang H, Ge C, Xiao S, Ding J, Geng M.

Cell Res. 2019 Oct;29(10):787-803. doi: 10.1038/s41422-019-0216-x. Epub 2019 Sep 6.


Value of ABCG2 Q141K and Q126X genotyping in predicting risk of preeclampsia in Chinese Han women population.

Hou H, Geng M, Zhang R, Liu W, Wang J, Li J, Lin Y, Liu S, Wang Z, Guo H, Guan H, Tan P.

Pregnancy Hypertens. 2019 Jul;17:197-202. doi: 10.1016/j.preghy.2019.06.006. Epub 2019 Jun 26.


Preclinical evaluation of 3D185, a novel potent inhibitor of FGFR1/2/3 and CSF-1R, in FGFR-dependent and macrophage-dominant cancer models.

Peng X, Hou P, Chen Y, Dai Y, Ji Y, Shen Y, Su Y, Liu B, Wang Y, Sun D, Jiang Y, Zha C, Xie Z, Ding J, Geng M, Ai J.

J Exp Clin Cancer Res. 2019 Aug 22;38(1):372. doi: 10.1186/s13046-019-1357-y.


Sevoflurane Exerts an Anti-depressive Action by Blocking the HMGB1/TLR4 Pathway in Unpredictable Chronic Mild Stress Rats.

Guo Z, Zhao F, Wang Y, Wang Y, Geng M, Zhang Y, Ma Q, Xu X.

J Mol Neurosci. 2019 Dec;69(4):546-556. doi: 10.1007/s12031-019-01380-2. Epub 2019 Jul 31.


Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design.

Wang Y, Dai Y, Wu X, Li F, Liu B, Li C, Liu Q, Zhou Y, Wang B, Zhu M, Cui R, Tan X, Xiong Z, Liu J, Tan M, Xu Y, Geng M, Jiang H, Liu H, Ai J, Zheng M.

J Med Chem. 2019 Aug 22;62(16):7473-7488. doi: 10.1021/acs.jmedchem.9b00510. Epub 2019 Aug 9.


EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells.

Chen YH, Lv H, Shen N, Wang XM, Tang S, Xiong B, Ding J, Geng MY, Huang M.

Acta Pharmacol Sin. 2019 Jul 17. doi: 10.1038/s41401-019-0268-y. [Epub ahead of print]


[Analyses of audiological examination in children without auditory brainstem response].

Zhang H, Geng MY, Mi YF, Shan ZL, Tang JF, Guo XY.

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Jul 7;54(7):540-543. doi: 10.3760/cma.j.issn.1673-0860.2019.07.011. Chinese.


Design, synthesis, and biological evaluation of a new class of histone acetyltransferase p300 inhibitors.

Liu R, Zhang Z, Yang H, Zhou K, Geng M, Zhou W, Zhang M, Huang X, Li Y.

Eur J Med Chem. 2019 Oct 15;180:171-190. doi: 10.1016/j.ejmech.2019.07.026. Epub 2019 Jul 9.


Abnormal Expression of DICER1 Leads to Dysregulation of Inflammatory Effectors in Human Synoviocytes.

Jiang C, Xu J, Zhu W, Cai Y, Wang S, Guo Y, Xu K, Geng M, Hussain N, Han Y, Zhang F, Ning Q, Meng L, Lu S.

Mediators Inflamm. 2019 May 28;2019:6768504. doi: 10.1155/2019/6768504. eCollection 2019.


The scrub typhus in mainland China: spatiotemporal expansion and risk prediction underpinned by complex factors.

Yao H, Wang Y, Mi X, Sun Y, Liu K, Li X, Ren X, Geng M, Yang Y, Wang L, Liu W, Fang L.

Emerg Microbes Infect. 2019;8(1):909-919. doi: 10.1080/22221751.2019.1631719.


Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer.

Jin N, Bi A, Lan X, Xu J, Wang X, Liu Y, Wang T, Tang S, Zeng H, Chen Z, Tan M, Ai J, Xie H, Zhang T, Liu D, Huang R, Song Y, Leung EL, Yao X, Ding J, Geng M, Lin SH, Huang M.

Nat Commun. 2019 Jun 20;10(1):2701. doi: 10.1038/s41467-019-10427-2.


PI3Kα inhibitors sensitize esophageal squamous cell carcinoma to radiation by abrogating survival signals in tumor cells and tumor microenvironment.

Shi JJ, Xing H, Wang YX, Zhang X, Zhan QM, Geng MY, Ding J, Meng LH.

Cancer Lett. 2019 Sep 10;459:145-155. doi: 10.1016/j.canlet.2019.05.040. Epub 2019 Jun 4.


Differential expression of the Hsf family in cassava under biotic and abiotic stresses.

Yu XY, Yao Y, Hong YH, Hou PY, Li CX, Xia ZQ, Geng MT, Chen YH.

Genome. 2019 Aug;62(8):563-569. doi: 10.1139/gen-2018-0163. Epub 2019 Jun 3.


Design and Synthesis of Potent, Selective Inhibitors of Protein Arginine Methyltransferase 4 against Acute Myeloid Leukemia.

Guo Z, Zhang Z, Yang H, Cao D, Xu X, Zheng X, Chen D, Wang Q, Li Y, Li J, Du Z, Wang X, Chen L, Ding J, Shen J, Geng M, Huang X, Xiong B.

J Med Chem. 2019 Jun 13;62(11):5414-5433. doi: 10.1021/acs.jmedchem.9b00297. Epub 2019 Jun 4.


Structural and molecular basis of angiotensin-converting enzyme by computational modeling: Insights into the mechanisms of different inhibitors.

Fang L, Geng M, Liu C, Wang J, Min W, Liu J.

PLoS One. 2019 Apr 18;14(4):e0215609. doi: 10.1371/journal.pone.0215609. eCollection 2019.


Discovery of a series of dimethoxybenzene FGFR inhibitors with 5H-pyrrolo[2,3-b]pyrazine scaffold: structure-activity relationship, crystal structural characterization and in vivo study.

Wei P, Liu B, Wang R, Gao Y, Li L, Ma Y, Qian Z, Chen Y, Cheng M, Geng M, Shen J, Zhao D, Ai J, Xiong B.

Acta Pharm Sin B. 2019 Mar;9(2):351-368. doi: 10.1016/j.apsb.2018.12.008. Epub 2018 Dec 26.


Discovery of Novel Janus Kinase (JAK) and Histone Deacetylase (HDAC) Dual Inhibitors for the Treatment of Hematological Malignancies.

Liang X, Zang J, Li X, Tang S, Huang M, Geng M, Chou CJ, Li C, Cao Y, Xu W, Liu H, Zhang Y.

J Med Chem. 2019 Apr 25;62(8):3898-3923. doi: 10.1021/acs.jmedchem.8b01597. Epub 2019 Apr 3.


Parallel Speciation of Wild Rice Associated with Habitat Shifts.

Cai Z, Zhou L, Ren NN, Xu X, Liu R, Huang L, Zheng XM, Meng QL, Du YS, Wang MX, Geng MF, Chen WL, Jing CY, Zou XH, Guo J, Chen CB, Zeng HZ, Liang YT, Wei XH, Guo YL, Zhou HF, Zhang FM, Ge S.

Mol Biol Evol. 2019 May 1;36(5):875-889. doi: 10.1093/molbev/msz029.


p53 β-hydroxybutyrylation attenuates p53 activity.

Liu K, Li F, Sun Q, Lin N, Han H, You K, Tian F, Mao Z, Li T, Tong T, Geng M, Zhao Y, Gu W, Zhao W.

Cell Death Dis. 2019 Mar 11;10(3):243. doi: 10.1038/s41419-019-1463-y.


[Clinical analysis of 54 patients with non-syndromic enlarged vestibular aqueduct].

Wang LL, Song YT, Geng MY, Mi YF, Guo XY, Wang L, Tang JF, Li Z, Li WC.

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Mar;33(3):255-258. doi: 10.13201/j.issn.1001-1781.2019.03.017. Chinese.


Sensor Fusion-Based Cooperative Trail Following for Autonomous Multi-Robot System.

Geng M, Liu S, Wu Z.

Sensors (Basel). 2019 Feb 17;19(4). pii: E823. doi: 10.3390/s19040823.


Draft Genome Sequence of the Lantibiotic-Producing Strain Streptococcus salivarius HS0302.

Geng M, Deng P, Mire T, Austin F, Smith L.

Microbiol Resour Announc. 2019 Jan 3;8(1). pii: e01410-18. doi: 10.1128/MRA.01410-18. eCollection 2019 Jan.


Effect of post-silking drought stress on the expression profiles of genes involved in carbon and nitrogen metabolism during leaf senescence in maize (Zea mays L.).

Yang M, Geng M, Shen P, Chen X, Li Y, Wen X.

Plant Physiol Biochem. 2019 Feb;135:304-309. doi: 10.1016/j.plaphy.2018.12.025. Epub 2018 Dec 25.


[Surveillance data on notifiable infectious diseases among students aged 6-22 years in China, 2011-2016].

Sun J, Yang WW, Zeng LJ, Geng MJ, Dong YH, Xing Y, Ma J, Li ZJ, Wang LP.

Zhonghua Liu Xing Bing Xue Za Zhi. 2018 Dec 10;39(12):1589-1595. doi: 10.3760/cma.j.issn.0254-6450.2018.12.010. Chinese.


Discovery and optimization of a series of 3-substituted indazole derivatives as multi-target kinase inhibitors for the treatment of lung squamous cell carcinoma.

Wang Q, Dai Y, Ji Y, Shi H, Guo Z, Chen D, Chen Y, Peng X, Gao Y, Wang X, Chen L, Jiang Y, Geng M, Shen J, Ai J, Xiong B.

Eur J Med Chem. 2019 Feb 1;163:671-689. doi: 10.1016/j.ejmech.2018.12.015. Epub 2018 Dec 7.


Fragment-based drug discovery of triazole inhibitors to block PDEδ-RAS protein-protein interaction.

Chen D, Chen Y, Lian F, Chen L, Li Y, Cao D, Wang X, Chen L, Li J, Meng T, Huang M, Geng M, Shen J, Zhang N, Xiong B.

Eur J Med Chem. 2019 Feb 1;163:597-609. doi: 10.1016/j.ejmech.2018.12.018. Epub 2018 Dec 11.


Density functional theory calculations and thermodynamic analysis of bridgmanite surface structure.

Geng M, Jónsson H.

Phys Chem Chem Phys. 2019 Jan 21;21(3):1009-1013. doi: 10.1039/c8cp06702c. Epub 2018 Dec 7.


The Secretome Engages STAT3 to Favor a Cytokine-rich Microenvironment in Mediating Acquired Resistance to FGFR Inhibitors.

Wang X, Ai J, Liu H, Peng X, Chen H, Chen Y, Su Y, Shen A, Huang X, Ding J, Geng M.

Mol Cancer Ther. 2019 Mar;18(3):667-679. doi: 10.1158/1535-7163.MCT-18-0179. Epub 2018 Dec 6.


Structural geology data and 3-D subsurface models of the Budgell Harbour Stock and associated dykes, Newfoundland, Canada.

Peace AL, Welford JK, Geng M, Sandeman H, Gaetz BD, Ryan SS.

Data Brief. 2018 Oct 25;21:1690-1696. doi: 10.1016/j.dib.2018.10.072. eCollection 2018 Dec.


[The associations between nighttime sleep duration, bedtime and preschool children's obesity].

Jiang L, Yan SQ, Geng ML, Gu CL, Huang K, Cao H, Wu XY, Tao FB.

Zhonghua Yu Fang Yi Xue Za Zhi. 2018 Nov 6;52(11):1146-1151. doi: 10.3760/cma.j.issn.0253-9624.2018.11.010. Chinese.


Discovery and structure-activity-relationship study of novel imidazole cyclopropyl amine analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors.

Zheng Q, Chen Z, Wan H, Tang S, Ye Y, Xu Y, Jiang L, Ding J, Geng M, Huang M, Huang Y.

Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3808-3812. doi: 10.1016/j.bmcl.2018.07.002. Epub 2018 Jul 4.


A new amphiphilic pillar[5]arene: synthesis and controllable self-assembly in water and application in white-light-emitting systems.

Sun S, Geng M, Huang L, Chen Y, Cen M, Lu D, Wang A, Wang Y, Shi Y, Yao Y.

Chem Commun (Camb). 2018 Nov 15;54(92):13006-13009. doi: 10.1039/c8cc07658h.


Correction to Discovery of Potent Irreversible Pan-Fibroblast Growth Factor Receptor (FGFR) Inhibitors.

Wang Y, Li L, Fan J, Dai Y, Jiang A, Geng M, Ai J, Duan W.

J Med Chem. 2018 Oct 25;61(20):9393. doi: 10.1021/acs.jmedchem.8b01414. Epub 2018 Oct 12. No abstract available.


A Novel Actin Binding Drug with In Vivo Efficacy.

Ravichandran A, Geng M, Hull KG, Li J, Romo D, Lu SE, Albee A, Nutter C, Gordon DM, Ghannoum MA, Lockless SW, Smith L.

Antimicrob Agents Chemother. 2018 Dec 21;63(1). pii: e01585-18. doi: 10.1128/AAC.01585-18. Print 2019 Jan.


Identification and expression analysis of MinD gene involved in plastid division in cassava.

Ke L, Cao LJ, Geng MT, Wang CC, Yao Y, Xiao Y, Huang W, Li RM, Min Y, Guo JC.

Biosci Biotechnol Biochem. 2019 Jan;83(1):76-86. doi: 10.1080/09168451.2018.1520075. Epub 2018 Oct 5.


Efficacious Analogs of the Lantibiotic Mutacin 1140 against a Systemic Methicillin-Resistant Staphylococcus aureus Infection.

Geng M, Ravichandran A, Escano J, Smith L.

Antimicrob Agents Chemother. 2018 Nov 26;62(12). pii: e01626-18. doi: 10.1128/AAC.01626-18. Print 2018 Dec.


Overexpression of MinE gene affects the plastid division in cassava.

Wang CC, Ke L, Cao LJ, Yao Y, Geng MT, Wang Y, Xiao Y, Huang W, Liu XH, Cao P, Guo JC, Min Y.

Biosci Biotechnol Biochem. 2018 Sep 27:1-11. doi: 10.1080/09168451.2018.1518703. [Epub ahead of print]


Cancer mortality attributable to cigarette smoking in 2005, 2010 and 2015 in Qingdao, China.

Xu Z, Qi F, Wang Y, Jia X, Lin P, Geng M, Wang R, Li S.

PLoS One. 2018 Sep 20;13(9):e0204221. doi: 10.1371/journal.pone.0204221. eCollection 2018.


CUDC-907 displays potent antitumor activity against human pancreatic adenocarcinoma in vitro and in vivo through inhibition of HDAC6 to downregulate c-Myc expression.

Fu XH, Zhang X, Yang H, Xu XW, Hu ZL, Yan J, Zheng XL, Wei RR, Zhang ZQ, Tang SR, Geng MY, Huang X.

Acta Pharmacol Sin. 2019 May;40(5):677-688. doi: 10.1038/s41401-018-0108-5. Epub 2018 Sep 17.


Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.

Huang X, Yan J, Zhang M, Wang Y, Chen Y, Fu X, Wei R, Zheng XL, Liu Z, Zhang X, Yang H, Hao B, Shen YY, Su Y, Cong X, Huang M, Tan M, Ding J, Geng M.

Cell. 2018 Sep 20;175(1):186-199.e19. doi: 10.1016/j.cell.2018.08.058. Epub 2018 Sep 13.

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