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Items: 1 to 50 of 66

1.

Experimental autoimmune encephalomyelitis potentiates mouse mast cell protease 4-dependent pressor responses to centrally or systemically administered big endothelin-1.

Desbiens L, Lapointe C, Gendron L, Gharagozloo M, Vincent L, Pejler G, Gris D, D'Orleans-Juste P.

J Pharmacol Exp Ther. 2019 Jun 27. pii: jpet.118.256016. doi: 10.1124/jpet.118.256016. [Epub ahead of print]

2.

Monitoring the Aggregation of GPCRs by Fluorescence Microscopy.

Génier S, Degrandmaison J, Lavoie CL, Gendron L, Parent JL.

Methods Mol Biol. 2019;1947:289-302. doi: 10.1007/978-1-4939-9121-1_16.

PMID:
30969423
3.

The combination of opioid and neurotensin receptor agonists improves their analgesic/adverse effect ratio.

Eiselt E, Côté J, Longpré JM, Blais V, Sarret P, Gendron L.

Eur J Pharmacol. 2019 Apr 5;848:80-87. doi: 10.1016/j.ejphar.2019.01.048. Epub 2019 Jan 29.

PMID:
30707956
4.

N-Guanidyl and C-Tetrazole Leu-Enkephalin Derivatives: Efficient Mu and Delta Opioid Receptor Agonists with Improved Pharmacological Properties.

Beaudeau JL, Blais V, Holleran BJ, Bergeron A, Piñeyro G, Guérin B, Gendron L, Dory YL.

ACS Chem Neurosci. 2019 Mar 20;10(3):1615-1626. doi: 10.1021/acschemneuro.8b00550. Epub 2019 Jan 23.

PMID:
30614675
5.

Active mind-body movement therapies as an adjunct to or in comparison with pulmonary rehabilitation for people with chronic obstructive pulmonary disease.

Gendron LM, Nyberg A, Saey D, Maltais F, Lacasse Y.

Cochrane Database Syst Rev. 2018 Oct 10;10:CD012290. doi: 10.1002/14651858.CD012290.pub2.

PMID:
30306545
6.

Corrigendum to "Chemical space screening around Phe3 in opioid peptides: Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings" [Bioorg. Med. Chem. Lett. 28(13) (2018) 2320-2323].

Willemse T, Eiselt E, Hollanders K, Schepens W, van Vlijmen HWT, Chung NN, Blais V, Holleran B, Longpré JM, Schiller PW, Maes BUW, Sarret P, Gendron L, Ballet S.

Bioorg Med Chem Lett. 2018 Nov 1;28(20):3418. doi: 10.1016/j.bmcl.2018.08.023. Epub 2018 Sep 5. No abstract available.

PMID:
30195888
7.

Chemical space screening around Phe3 in opioid peptides: Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings.

Willemse T, Eiselt E, Hollanders K, Schepens W, van Vlijmen HWT, Chung NN, Blais V, Holleran B, Longpré JM, Schiller PW, Maes BUW, Sarret P, Gendron L, Ballet S.

Bioorg Med Chem Lett. 2018 Jul 15;28(13):2320-2323. doi: 10.1016/j.bmcl.2018.05.015. Epub 2018 May 12. Erratum in: Bioorg Med Chem Lett. 2018 Nov 1;28(20):3418.

8.

Adeno-associated virus 2/9 delivery of Cre recombinase in mouse primary afferents.

Abdallah K, Nadeau F, Bergeron F, Blouin S, Blais V, Bradbury KM, Lavoie CL, Parent JL, Gendron L.

Sci Rep. 2018 May 9;8(1):7321. doi: 10.1038/s41598-018-25626-y.

9.

Delta Opioid Receptor Signaling Promotes Resilience to Stress Under the Repeated Social Defeat Paradigm in Mice.

Henry MS, Bisht K, Vernoux N, Gendron L, Torres-Berrio A, Drolet G, Tremblay MÈ.

Front Mol Neurosci. 2018 Apr 6;11:100. doi: 10.3389/fnmol.2018.00100. eCollection 2018.

10.

Delta opioid receptors recycle to the membrane after sorting to the degradation path.

Charfi I, Abdallah K, Gendron L, Pineyro G.

Cell Mol Life Sci. 2018 Jun;75(12):2257-2271. doi: 10.1007/s00018-017-2732-5. Epub 2017 Dec 29.

PMID:
29288293
11.

χ-Space Screening of Dermorphin-Based Tetrapeptides through Use of Constrained Arylazepinone and Quinolinone Scaffolds.

Van der Poorten O, Van Den Hauwe R, Eiselt E, Betti C, Guillemyn K, Chung NN, Hallé F, Bihel F, Schiller PW, Tourwé D, Sarret P, Gendron L, Ballet S.

ACS Med Chem Lett. 2017 Oct 4;8(11):1177-1182. doi: 10.1021/acsmedchemlett.7b00347. eCollection 2017 Nov 9.

12.

Enkephalins: Endogenous Analgesics with an Emerging Role in Stress Resilience.

Henry MS, Gendron L, Tremblay ME, Drolet G.

Neural Plast. 2017;2017:1546125. doi: 10.1155/2017/1546125. Epub 2017 Jul 11. Review.

13.

The Delta Opioid Receptor in Pain Control.

Abdallah K, Gendron L.

Handb Exp Pharmacol. 2018;247:147-177. doi: 10.1007/164_2017_32. Review.

PMID:
28510066
14.

Synthesis and Evaluation of a 64Cu-Conjugate, a Selective δ-Opioid Receptor Positron Emission Tomography Imaging Agent.

Pirisedigh A, Blais V, Ait-Mohand S, Abdallah K, Holleran BJ, Leduc R, Dory YL, Gendron L, Guérin B.

Org Lett. 2017 Apr 21;19(8):2018-2021. doi: 10.1021/acs.orglett.7b00575. Epub 2017 Apr 3.

PMID:
28368122
15.

Involvement of the coatomer protein complex I in the intracellular traffic of the delta opioid receptor.

St-Louis É, Degrandmaison J, Grastilleur S, Génier S, Blais V, Lavoie C, Parent JL, Gendron L.

Mol Cell Neurosci. 2017 Mar;79:53-63. doi: 10.1016/j.mcn.2016.12.005. Epub 2016 Dec 30.

16.

Synthesis of Gly-ψ[(Z)CF═CH]-Phe, a Fluoroalkene Dipeptide Isostere, and Its Incorporation into a Leu-enkephalin Peptidomimetic.

Nadon JF, Rochon K, Grastilleur S, Langlois G, Dao TT, Blais V, Guérin B, Gendron L, Dory YL.

ACS Chem Neurosci. 2017 Jan 18;8(1):40-49. doi: 10.1021/acschemneuro.6b00163. Epub 2016 Nov 3.

PMID:
27762555
17.

Increased radiosensitivity of colorectal tumors with intra-tumoral injection of low dose of gold nanoparticles.

Shi M, Paquette B, Thippayamontri T, Gendron L, Guérin B, Sanche L.

Int J Nanomedicine. 2016 Oct 12;11:5323-5333. eCollection 2016.

18.

Molecular Pharmacology of δ-Opioid Receptors.

Gendron L, Cahill CM, von Zastrow M, Schiller PW, Pineyro G.

Pharmacol Rev. 2016 Jul;68(3):631-700. doi: 10.1124/pr.114.008979. Review.

19.

iRAGE as a novel carboxymethylated peptide that prevents advanced glycation end product-induced apoptosis and endoplasmic reticulum stress in vascular smooth muscle cells.

Maltais JS, Simard E, Froehlich U, Denault JB, Gendron L, Grandbois M.

Pharmacol Res. 2016 Feb;104:176-85. doi: 10.1016/j.phrs.2015.12.015. Epub 2015 Dec 17.

PMID:
26707030
20.
21.

Regulation of μ and δ opioid receptor functions: involvement of cyclin-dependent kinase 5.

Beaudry H, Mercier-Blais AA, Delaygue C, Lavoie C, Parent JL, Neugebauer W, Gendron L.

Br J Pharmacol. 2015 May;172(10):2573-87. doi: 10.1111/bph.13088. Epub 2015 Mar 24.

22.

Identification of N-[(5-{[(4-methylphenyl)sulfonyl]amino}-3-(trifluoroacetyl)-1H-indol-1-yl)acetyl]-l-leucine (NTRC-824), a neurotensin-like nonpeptide compound selective for the neurotensin receptor type 2.

Thomas JB, Giddings AM, Wiethe RW, Olepu S, Warner KR, Sarret P, Gendron L, Longpre JM, Zhang Y, Runyon SP, Gilmour BP.

J Med Chem. 2014 Sep 11;57(17):7472-7. doi: 10.1021/jm500857r. Epub 2014 Aug 26.

23.

Label-free monitoring of μ-opioid receptor-mediated signaling.

Bourassa P, Tudashki HB, Pineyro G, Grandbois M, Gendron L.

Mol Pharmacol. 2014 Aug;86(2):138-49. doi: 10.1124/mol.114.093450. Epub 2014 May 29.

PMID:
24874699
24.

Identification of 1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane carboxylic acid as a selective nonpeptide neurotensin receptor type 2 compound.

Thomas JB, Giddings AM, Wiethe RW, Olepu S, Warner KR, Sarret P, Gendron L, Longpre JM, Zhang Y, Runyon SP, Gilmour BP.

J Med Chem. 2014 Jun 26;57(12):5318-32. doi: 10.1021/jm5003843. Epub 2014 Jun 5.

25.

Recent advances on the δ opioid receptor: from trafficking to function.

Gendron L, Mittal N, Beaudry H, Walwyn W.

Br J Pharmacol. 2015 Jan;172(2):403-19. doi: 10.1111/bph.12706. Epub 2014 Jul 1. Review.

26.

Involvement of cannabinoid receptors in peripheral and spinal morphine analgesia.

Desroches J, Bouchard JF, Gendron L, Beaulieu P.

Neuroscience. 2014 Mar 7;261:23-42. doi: 10.1016/j.neuroscience.2013.12.030. Epub 2013 Dec 21.

27.

Systematic replacement of amides by 1,4-disubstituted[1,2,3]triazoles in Leu-enkephalin and the impact on the delta opioid receptor activity.

Proteau-Gagné A, Rochon K, Roy M, Albert PJ, Guérin B, Gendron L, Dory YL.

Bioorg Med Chem Lett. 2013 Oct 1;23(19):5267-9. doi: 10.1016/j.bmcl.2013.08.020. Epub 2013 Aug 12.

28.

Spinal μ and δ opioids inhibit both thermal and mechanical pain in rats.

Normandin A, Luccarini P, Molat JL, Gendron L, Dallel R.

J Neurosci. 2013 Jul 10;33(28):11703-14. doi: 10.1523/JNEUROSCI.1631-13.2013.

29.

Preparation and evaluation at the delta opioid receptor of a series of linear leu-enkephalin analogues obtained by systematic replacement of the amides.

Rochon K, Proteau-Gagné A, Bourassa P, Nadon JF, Côté J, Bournival V, Gobeil F Jr, Guérin B, Dory YL, Gendron L.

ACS Chem Neurosci. 2013 Aug 21;4(8):1204-16. doi: 10.1021/cn4000583. Epub 2013 May 20.

30.

Pain after discontinuation of morphine treatment is associated with synaptic increase of GluA4-containing AMPAR in the dorsal horn of the spinal cord.

Cabañero D, Baker A, Zhou S, Hargett GL, Irie T, Xia Y, Beaudry H, Gendron L, Melyan Z, Carlton SM, Morón JA.

Neuropsychopharmacology. 2013 Jul;38(8):1472-84. doi: 10.1038/npp.2013.46. Epub 2013 Feb 12.

31.

Label-free monitoring of apoptosis by surface plasmon resonance detection of morphological changes.

Maltais JS, Denault JB, Gendron L, Grandbois M.

Apoptosis. 2012 Aug;17(8):916-25. doi: 10.1007/s10495-012-0737-y.

PMID:
22644572
32.

Increased anxiety-like behaviors in rats experiencing chronic inflammatory pain.

Parent AJ, Beaudet N, Beaudry H, Bergeron J, Bérubé P, Drolet G, Sarret P, Gendron L.

Behav Brain Res. 2012 Apr 1;229(1):160-7. doi: 10.1016/j.bbr.2012.01.001. Epub 2012 Jan 8.

33.

Evaluation of bacterial contaminants found on unused paper towels and possible postcontamination after handwashing: a pilot study.

Gendron LM, Trudel L, Moineau S, Duchaine C.

Am J Infect Control. 2012 Mar;40(2):e5-9. doi: 10.1016/j.ajic.2011.07.007. Epub 2011 Dec 16.

PMID:
22177666
34.

Activation of spinal mu- and delta-opioid receptors potently inhibits substance P release induced by peripheral noxious stimuli.

Beaudry H, Dubois D, Gendron L.

J Neurosci. 2011 Sep 14;31(37):13068-77. doi: 10.1523/JNEUROSCI.1817-11.2011.

35.

Spinal activation of delta opioid receptors alleviates cancer-related bone pain.

Otis V, Sarret P, Gendron L.

Neuroscience. 2011 Jun 2;183:221-9. doi: 10.1016/j.neuroscience.2011.03.052. Epub 2011 Mar 31.

36.

Presence of task-1 channel in the laryngeal mucosa in the newborn lamb.

Bournival V, Desjardins R, Campbell S, Roberge C, Doueik A, Gendron L, Payet MD, Gallo-Payet N, Day R, Praud JP.

Exp Lung Res. 2011 May;37(4):205-11. doi: 10.3109/01902148.2010.536610. Epub 2011 Feb 11.

PMID:
21309733
37.

Detection of airborne lactococcal bacteriophages in cheese manufacturing plants.

Verreault D, Gendron L, Rousseau GM, Veillette M, Massé D, Lindsley WG, Moineau S, Duchaine C.

Appl Environ Microbiol. 2011 Jan;77(2):491-7. doi: 10.1128/AEM.01391-10. Epub 2010 Nov 29.

38.

Exploring the Backbone of Enkephalins To Adjust Their Pharmacological Profile for the δ-Opioid Receptor.

Proteau-Gagné A, Bournival V, Rochon K, Dory YL, Gendron L.

ACS Chem Neurosci. 2010 Nov 17;1(11):757-69. doi: 10.1021/cn1000759. Epub 2010 Sep 17.

39.

Behavioral, medical imaging and histopathological features of a new rat model of bone cancer pain.

Doré-Savard L, Otis V, Belleville K, Lemire M, Archambault M, Tremblay L, Beaudoin JF, Beaudet N, Lecomte R, Lepage M, Gendron L, Sarret P.

PLoS One. 2010 Oct 29;5(10):e13774. doi: 10.1371/journal.pone.0013774.

40.

Delta opioid receptor-mediated analgesia is not altered in preprotachykinin A knockout mice.

Dubois D, Gendron L.

Eur J Neurosci. 2010 Dec;32(11):1921-9. doi: 10.1111/j.1460-9568.2010.07466.x. Epub 2010 Oct 29.

PMID:
21044181
41.

Altered morphine-induced analgesia in neurotensin type 1 receptor null mice.

Roussy G, Beaudry H, Lafrance M, Belleville K, Beaudet N, Wada K, Gendron L, Sarret P.

Neuroscience. 2010 Nov 10;170(4):1286-94. doi: 10.1016/j.neuroscience.2010.08.016. Epub 2010 Aug 18.

42.

Detection and identification of multiple genetically modified events using DNA insert fingerprinting.

Raymond P, Gendron L, Khalf M, Paul S, Dibley KL, Bhat S, Xie VR, Partis L, Moreau ME, Dollard C, Coté MJ, Laberge S, Emslie KR.

Anal Bioanal Chem. 2010 Mar;396(6):2091-102. doi: 10.1007/s00216-009-3295-6. Epub 2009 Nov 27.

PMID:
19943159
43.

Airborne porcine circovirus in Canadian swine confinement buildings.

Verreault D, Létourneau V, Gendron L, Massé D, Gagnon CA, Duchaine C.

Vet Microbiol. 2010 Mar 24;141(3-4):224-30. doi: 10.1016/j.vetmic.2009.09.013. Epub 2009 Sep 11.

PMID:
19773132
44.

In situ detection of antibiotic-resistance elements in single Bacillus cereus spores.

Laflamme C, Gendron L, Turgeon N, Filion G, Ho J, Duchaine C.

Syst Appl Microbiol. 2009 Aug;32(5):323-33. doi: 10.1016/j.syapm.2009.03.003. Epub 2009 May 14.

PMID:
19446419
45.

Differential noxious and motor tolerance of chronic delta opioid receptor agonists in rodents.

Beaudry H, Proteau-Gagné A, Li S, Dory Y, Chavkin C, Gendron L.

Neuroscience. 2009 Jun 30;161(2):381-91. doi: 10.1016/j.neuroscience.2009.03.053. Epub 2009 Mar 27.

46.

Essential role of mu opioid receptor in the regulation of delta opioid receptor-mediated antihyperalgesia.

Gendron L, Pintar JE, Chavkin C.

Neuroscience. 2007 Dec 19;150(4):807-17. Epub 2007 Oct 5.

47.
48.

Coexpression of somatostatin receptor subtype 5 affects internalization and trafficking of somatostatin receptor subtype 2.

Sharif N, Gendron L, Wowchuk J, Sarret P, Mazella J, Beaudet A, Stroh T.

Endocrinology. 2007 May;148(5):2095-105. Epub 2007 Feb 1.

PMID:
17272399
49.

Morphine priming in rats with chronic inflammation reveals a dichotomy between antihyperalgesic and antinociceptive properties of deltorphin.

Gendron L, Esdaile MJ, Mennicken F, Pan H, O'Donnell D, Vincent JP, Devi LA, Cahill CM, Stroh T, Beaudet A.

Neuroscience. 2007 Jan 5;144(1):263-74. Epub 2006 Oct 19.

50.

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