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Items: 1 to 50 of 1111

1.

Cranberry, D-mannose and anti-inflammatory agents prevent lower urinary tract symptoms in women undergoing prolapse surgery.

Russo E, Montt Guevara M, Giannini A, Mannella P, Palla G, Caretto M, Pancetti F, Genazzani AD, Simoncini T.

Climacteric. 2019 Nov 1:1-5. doi: 10.1080/13697137.2019.1679110. [Epub ahead of print]

PMID:
31674202
2.

A luminal EF-hand mutation in STIM1 in mice causes the clinical hallmarks of tubular aggregate myopathy.

Cordero-Sanchez C, Riva B, Reano S, Clemente N, Zaggia I, Ruffinatti FA, Potenzieri A, Pirali T, Raffa S, Sangaletti S, Colombo MP, Bertoni A, Garibaldi M, Filigheddu N, Genazzani AA.

Dis Model Mech. 2019 Oct 30. pii: dmm.041111. doi: 10.1242/dmm.041111. [Epub ahead of print]

3.

Oxaliplatin-induced neuropathy occurs via impairment of haemoglobin proton buffering and is reversed by carbonic anhydrase inhibitors.

Potenzieri A, Riva B, Rigolio R, Chiorazzi A, Pozzi E, Ballarini E, Cavaletti G, Genazzani AA.

Pain. 2019 Oct 17. doi: 10.1097/j.pain.0000000000001722. [Epub ahead of print]

PMID:
31634341
4.

Deletion of calcineurin from GFAP-expressing astrocytes impairs excitability of cerebellar and hippocampal neurons through astroglial Na+ /K+ ATPase.

Tapella L, Soda T, Mapelli L, Bortolotto V, Bondi H, Ruffinatti FA, Dematteis G, Stevano A, Dionisi M, Ummarino S, Di Ruscio A, Distasi C, Grilli M, Genazzani AA, D'Angelo E, Moccia F, Lim D.

Glia. 2019 Oct 18. doi: 10.1002/glia.23737. [Epub ahead of print]

PMID:
31626368
5.

Identification of potent triazolylpyridine nicotinamide phosphoribosyltransferase (NAMPT) inhibitors bearing a 1,2,3-triazole tail group.

Travelli C, Aprile S, Mattoteia D, Colombo G, Clemente N, Scanziani E, Terrazzino S, Alisi MA, Polenzani L, Grosa G, Genazzani AA, Tron GC, Galli U.

Eur J Med Chem. 2019 Nov 1;181:111576. doi: 10.1016/j.ejmech.2019.111576. Epub 2019 Aug 1.

PMID:
31400709
6.

Differential insulin response to oral glucose tolerance test (OGTT) in overweight/obese polycystic ovary syndrome patients undergoing to myo-inositol (MYO), alpha lipoic acid (ALA), or combination of both.

Genazzani AD, Prati A, Marchini F, Petrillo T, Napolitano A, Simoncini T.

Gynecol Endocrinol. 2019 Dec;35(12):1088-1093. doi: 10.1080/09513590.2019.1640200. Epub 2019 Jul 13.

PMID:
31304823
7.

Absinthin, an agonist of the bitter taste receptor hTAS2R46, uncovers an ER-to-mitochondria Ca2+-shuttling event.

Talmon M, Rossi S, Lim D, Pollastro F, Palattella G, Ruffinatti FA, Marotta P, Boldorini R, Genazzani AA, Fresu LG.

J Biol Chem. 2019 Aug 16;294(33):12472-12482. doi: 10.1074/jbc.RA119.007763. Epub 2019 Jun 27.

PMID:
31248983
8.

A case of premature ovarian insufficiency in Nijmegen breakage syndrome patient and review of literature. From gene mutation to clinical management.

Szeliga A, Zysnarska A, Szklarska Z, Truszkowska E, Podfigurna A, Czyzyk A, Genazzani AR, Chrzanowska K, Meczekalski B.

Gynecol Endocrinol. 2019 Nov;35(11):999-1002. doi: 10.1080/09513590.2019.1626366. Epub 2019 Jun 12.

PMID:
31187634
9.

The INN global nomenclature of biological medicines: A continuous challenge.

Robertson JS, Chui WK, Genazzani AA, Malan SF, López de la Rica Manjavacas A, Mignot G, Thorpe R, Balocco R, Rizzi M.

Biologicals. 2019 Jul;60:15-23. doi: 10.1016/j.biologicals.2019.05.006. Epub 2019 May 23. Review.

10.

Corrigendum to "Inositol and In Vitro Fertilization with Embryo Transfer".

Simi G, Genazzani AR, Obino MER, Papini F, Pinelli S, Cela V, Artini PG.

Int J Endocrinol. 2019 Apr 11;2019:8309405. doi: 10.1155/2019/8309405. eCollection 2019.

11.

Drug Discovery for Soft Drugs on TRPV1 and TRPM8 Channels Using the Passerini Reaction.

Pirali T, Galli U, Serafini M, Griglio A, Genazzani AA, Tron GC.

Methods Mol Biol. 2019;1987:207-221. doi: 10.1007/978-1-4939-9446-5_13.

PMID:
31028682
12.

Oral dehydroepiandrosterone restores ß-endorphin response to OGTT in early and late postmenopause.

Giannini A, Genazzani AD, Napolitano A, Caretto M, Stomati M, Simoncini T, Genazzani AR.

Gynecol Endocrinol. 2019 Sep;35(9):767-771. doi: 10.1080/09513590.2019.1590548. Epub 2019 Apr 2.

PMID:
30935252
13.

Nicotinamide Phosphoribosyltransferase Acts as a Metabolic Gate for Mobilization of Myeloid-Derived Suppressor Cells.

Travelli C, Consonni FM, Sangaletti S, Storto M, Morlacchi S, Grolla AA, Galli U, Tron GC, Portararo P, Rimassa L, Pressiani T, Mazzone M, Trovato R, Ugel S, Bronte V, Tripodo C, Colombo MP, Genazzani AA, Sica A.

Cancer Res. 2019 Apr 15;79(8):1938-1951. doi: 10.1158/0008-5472.CAN-18-1544. Epub 2019 Feb 18.

PMID:
30777853
14.

Brain intracrinology of allopregnanolone during pregnancy and hormonal contraception.

Pluchino N, Ansaldi Y, Genazzani AR.

Horm Mol Biol Clin Investig. 2019 Feb 11;37(1). pii: /j/hmbci.2019.37.issue-1/hmbci-2018-0032/hmbci-2018-0032.xml. doi: 10.1515/hmbci-2018-0032. Review.

PMID:
30739099
15.

Oral investigational drugs currently in phase I or phase II for the amelioration of menopausal symptoms.

Genazzani AR, Gaspard U, Foidart JM.

Expert Opin Investig Drugs. 2019 Mar;28(3):235-247. doi: 10.1080/13543784.2019.1572114. Epub 2019 Feb 1. Review.

PMID:
30677323
16.

Applications of Deuterium in Medicinal Chemistry.

Pirali T, Serafini M, Cargnin S, Genazzani AA.

J Med Chem. 2019 Jun 13;62(11):5276-5297. doi: 10.1021/acs.jmedchem.8b01808. Epub 2019 Jan 25.

PMID:
30640460
17.

Gene expression, proteome and calcium signaling alterations in immortalized hippocampal astrocytes from an Alzheimer's disease mouse model.

Rocchio F, Tapella L, Manfredi M, Chisari M, Ronco F, Ruffinatti FA, Conte E, Canonico PL, Sortino MA, Grilli M, Marengo E, Genazzani AA, Lim D.

Cell Death Dis. 2019 Jan 10;10(1):24. doi: 10.1038/s41419-018-1264-8.

18.

Optimizing quality of life through sex steroids by their effects on neurotransmitters.

Giannini A, Caretto M, Genazzani AR, Simoncini T.

Climacteric. 2019 Feb;22(1):55-59. doi: 10.1080/13697137.2018.1543265. Epub 2018 Dec 20.

PMID:
30570355
19.

Pyrtriazoles, a Novel Class of Store-Operated Calcium Entry Modulators: Discovery, Biological Profiling, and in Vivo Proof-of-Concept Efficacy in Acute Pancreatitis.

Riva B, Griglio A, Serafini M, Cordero-Sanchez C, Aprile S, Di Paola R, Gugliandolo E, Alansary D, Biocotino I, Lim D, Grosa G, Galli U, Niemeyer B, Sorba G, Canonico PL, Cuzzocrea S, Genazzani AA, Pirali T.

J Med Chem. 2018 Nov 8;61(21):9756-9783. doi: 10.1021/acs.jmedchem.8b01512. Epub 2018 Oct 30.

PMID:
30347159
20.

Oxaliplatin induces pH acidification in dorsal root ganglia neurons.

Riva B, Dionisi M, Potenzieri A, Chiorazzi A, Cordero-Sanchez C, Rigolio R, Carozzi VA, Lim D, Cavaletti G, Marmiroli P, Distasi C, Genazzani AA.

Sci Rep. 2018 Oct 10;8(1):15084. doi: 10.1038/s41598-018-33508-6.

21.

Neuronal Activity-Dependent Activation of Astroglial Calcineurin in Mouse Primary Hippocampal Cultures.

Lim D, Mapelli L, Canonico PL, Moccia F, Genazzani AA.

Int J Mol Sci. 2018 Sep 30;19(10). pii: E2997. doi: 10.3390/ijms19102997.

22.

Diagnostic accuracy of NUDT15 gene variants for thiopurine-induced leukopenia: a systematic review and meta-analysis.

Cargnin S, Genazzani AA, Canonico PL, Terrazzino S.

Pharmacol Res. 2018 Sep;135:102-111. doi: 10.1016/j.phrs.2018.07.021. Epub 2018 Jul 23.

PMID:
30048756
23.

Endometrium receptivity in premature ovarian insufficiency - how to improve fertility rate and predict diseases?

Vujović S, Ivovic M, Tančić-Gajić M, Marina L, Ljubic A, Dragojević-Dikić S, Genazzani AR.

Gynecol Endocrinol. 2018 Dec;34(12):1011-1015. doi: 10.1080/09513590.2018.1490715. Epub 2018 Jul 25. Review.

PMID:
30044147
24.

NAMPT: A pleiotropic modulator of monocytes and macrophages.

Travelli C, Colombo G, Mola S, Genazzani AA, Porta C.

Pharmacol Res. 2018 Sep;135:25-36. doi: 10.1016/j.phrs.2018.06.022. Epub 2018 Jul 18. Review.

PMID:
30031171
25.

Dehydroepiandrosterone and Cardiovascular Disease.

Mannella P, Simoncini T, Caretto M, Genazzani AR.

Vitam Horm. 2018;108:333-353. doi: 10.1016/bs.vh.2018.05.001. Epub 2018 Jul 13.

PMID:
30029733
26.

Ulipristal Acetate Interferes With Actin Remodeling Induced by 17β-Estradiol and Progesterone in Human Endometrial Stromal Cells.

Shortrede JE, Montt-Guevara MM, Pennacchio G, Finiguerra M, Giannini A, Genazzani AD, Simoncini T.

Front Endocrinol (Lausanne). 2018 Jun 27;9:350. doi: 10.3389/fendo.2018.00350. eCollection 2018.

27.

The role of kisspeptin/neurokinin B/dynorphin neurons in pathomechanism of vasomotor symptoms in postmenopausal women: from physiology to potential therapeutic applications.

Szeliga A, Czyzyk A, Podfigurna A, Genazzani AR, Genazzani AD, Meczekalski B.

Gynecol Endocrinol. 2018 Nov;34(11):913-919. doi: 10.1080/09513590.2018.1480711. Epub 2018 Jun 14. Review.

PMID:
29902942
28.

Transcriptional Remodeling in Primary Hippocampal Astrocytes from an Alzheimer's Disease Mouse Model.

Ruffinatti F, Tapella L, Gregnanin I, Stevano A, Chiorino G, Canonico PL, Distasi C, Genazzani AA, Lim D.

Curr Alzheimer Res. 2018;15(11):986-1004. doi: 10.2174/1567205015666180613113924.

PMID:
29895250
29.

Regulatory Actions of LH and Follicle-Stimulating Hormone on Breast Cancer Cells and Mammary Tumors in Rats.

Sanchez AM, Flamini MI, Zullino S, Russo E, Giannini A, Mannella P, Naccarato AG, Genazzani AR, Simoncini T.

Front Endocrinol (Lausanne). 2018 May 16;9:239. doi: 10.3389/fendo.2018.00239. eCollection 2018.

30.

Kisspeptin and LH pulsatile temporal coupling in PCOS patients.

Katulski K, Podfigurna A, Czyzyk A, Meczekalski B, Genazzani AD.

Endocrine. 2018 Jul;61(1):149-157. doi: 10.1007/s12020-018-1609-1. Epub 2018 May 4.

31.

Targeting Transient Receptor Potential Vanilloid 1 (TRPV1) Channel Softly: The Discovery of Passerini Adducts as a Topical Treatment for Inflammatory Skin Disorders.

Serafini M, Griglio A, Aprile S, Seiti F, Travelli C, Pattarino F, Grosa G, Sorba G, Genazzani AA, Gonzalez-Rodriguez S, Butron L, Devesa I, Fernandez-Carvajal A, Pirali T, Ferrer-Montiel A.

J Med Chem. 2018 May 24;61(10):4436-4455. doi: 10.1021/acs.jmedchem.8b00109. Epub 2018 May 15.

PMID:
29722529
32.

Symptoms of menopause - global prevalence, physiology and implications.

Monteleone P, Mascagni G, Giannini A, Genazzani AR, Simoncini T.

Nat Rev Endocrinol. 2018 Apr;14(4):199-215. doi: 10.1038/nrendo.2017.180. Epub 2018 Feb 2. Review.

PMID:
29393299
33.

TGF-β2 and TGF-β3 from cultured β-amyloid-treated or 3xTg-AD-derived astrocytes may mediate astrocyte-neuron communication.

Tapella L, Cerruti M, Biocotino I, Stevano A, Rocchio F, Canonico PL, Grilli M, Genazzani AA, Lim D.

Eur J Neurosci. 2018 Feb;47(3):211-221. doi: 10.1111/ejn.13819. Epub 2018 Jan 18.

PMID:
29283464
34.

Modulatory effects of alpha-lipoic acid (ALA) administration on insulin sensitivity in obese PCOS patients.

Genazzani AD, Shefer K, Della Casa D, Prati A, Napolitano A, Manzo A, Despini G, Simoncini T.

J Endocrinol Invest. 2018 May;41(5):583-590. doi: 10.1007/s40618-017-0782-z. Epub 2017 Oct 31.

PMID:
29090431
35.

Susceptibility of different mouse strains to oxaliplatin peripheral neurotoxicity: Phenotypic and genotypic insights.

Marmiroli P, Riva B, Pozzi E, Ballarini E, Lim D, Chiorazzi A, Meregalli C, Distasi C, Renn CL, Semperboni S, Morosi L, Ruffinatti FA, Zucchetti M, Dorsey SG, Cavaletti G, Genazzani A, Carozzi VA.

PLoS One. 2017 Oct 11;12(10):e0186250. doi: 10.1371/journal.pone.0186250. eCollection 2017.

36.

Correlation between allopregnanolone levels and depressive symptoms during late menopausal transition and early postmenopause.

Slopien R, Pluchino N, Warenik-Szymankiewicz A, Sajdak S, Luisi M, Drakopoulos P, Genazzani AR.

Gynecol Endocrinol. 2018 Feb;34(2):144-147. doi: 10.1080/09513590.2017.1371129. Epub 2017 Aug 31.

PMID:
28857628
37.

Inositol supplementation in women with polycystic ovary syndrome undergoing intracytoplasmic sperm injection: a systematic review and meta-analysis of randomized controlled trials.

Mendoza N, Pérez L, Simoncini T, Genazzani A.

Reprod Biomed Online. 2017 Nov;35(5):529-535. doi: 10.1016/j.rbmo.2017.07.005. Epub 2017 Jul 14. Review.

PMID:
28756130
38.

Chemotherapy-induced peripheral neurotoxicity: management informed by pharmacogenetics.

Argyriou AA, Bruna J, Genazzani AA, Cavaletti G.

Nat Rev Neurol. 2017 Aug;13(8):492-504. doi: 10.1038/nrneurol.2017.88. Epub 2017 Jun 30. Review.

PMID:
28664909
39.

Severe hyperandrogenemia in postmenopausal woman as a presentation of ovarian hyperthecosis. Case report and mini review of the literature.

Czyzyk A, Latacz J, Filipowicz D, Podfigurna A, Moszynski R, Jasinski P, Sajdak S, Gaca M, Genazzani AR, Meczekalski B.

Gynecol Endocrinol. 2017 Nov;33(11):836-839. doi: 10.1080/09513590.2017.1337094. Epub 2017 Jun 11. Review.

PMID:
28604129
40.

Modulatory effects of l-carnitine plus l-acetyl-carnitine on neuroendocrine control of hypothalamic functions in functional hypothalamic amenorrhea (FHA).

Genazzani AD, Despini G, Czyzyk A, Podfigurna A, Simoncini T, Meczekalski B.

Gynecol Endocrinol. 2017 Dec;33(12):963-967. doi: 10.1080/09513590.2017.1332587. Epub 2017 Jun 2.

PMID:
28573875
41.

Metabolic regulation of suppressive myeloid cells in cancer.

Sica A, Strauss L, Consonni FM, Travelli C, Genazzani A, Porta C.

Cytokine Growth Factor Rev. 2017 Jun;35:27-35. doi: 10.1016/j.cytogfr.2017.05.002. Epub 2017 May 3. Review.

PMID:
28499577
42.

Homer1b/c clustering is impaired in Phelan-McDermid Syndrome iPSCs derived neurons.

Vicidomini C, Ponzoni L, Lim D, Schmeisser MJ, Reim D, Morello N, Orellana D, Tozzi A, Durante V, Scalmani P, Mantegazza M, Genazzani AA, Giustetto M, Sala M, Calabresi P, Boeckers TM, Sala C, Verpelli C.

Mol Psychiatry. 2017 May;22(5):637. doi: 10.1038/mp.2017.82. No abstract available.

PMID:
28428614
43.

Synthesis and Degradation of Adenosine 5'-Tetraphosphate by Nicotinamide and Nicotinate Phosphoribosyltransferases.

Amici A, Grolla AA, Del Grosso E, Bellini R, Bianchi M, Travelli C, Garavaglia S, Sorci L, Raffaelli N, Ruggieri S, Genazzani AA, Orsomando G.

Cell Chem Biol. 2017 May 18;24(5):553-564.e4. doi: 10.1016/j.chembiol.2017.03.010. Epub 2017 Apr 13.

44.

Inositol and In Vitro Fertilization with Embryo Transfer.

Simi G, Genazzani AR, Obino ME, Papini F, Pinelli S, Cela V, Artini PG.

Int J Endocrinol. 2017;2017:5469409. doi: 10.1155/2017/5469409. Epub 2017 Feb 28. Review. Erratum in: Int J Endocrinol. 2019 Apr 11;2019:8309405.

45.

Pilot cohort study on the potential role of TCF7L2 rs7903146 on ischemic heart disease among non-diabetic kidney transplant recipients.

Quaglia M, Musetti C, Merlotti G, Genazzani AA, Cargnin S, Cena T, Cantaluppi V, Terrazzino S.

Clin Transplant. 2017 Jun;31(6). doi: 10.1111/ctr.12959. Epub 2017 Apr 17.

PMID:
28299838
46.

The role of progesterone therapy in early pregnancy: from physiological role to therapeutic utility.

Czyzyk A, Podfigurna A, Genazzani AR, Meczekalski B.

Gynecol Endocrinol. 2017 Jun;33(6):421-424. doi: 10.1080/09513590.2017.1291615. Epub 2017 Feb 28. Review.

PMID:
28277122
47.

Brain-derived neurotrophic factor (BDNF) plasma concentration in patients diagnosed with premature ovarian insufficiency (POI).

Czyzyk A, Filipowicz D, Podfigurna A, Ptas P, Piestrzynska M, Smolarczyk R, Genazzani AR, Meczekalski B.

Gynecol Endocrinol. 2017 May;33(5):413-417. doi: 10.1080/09513590.2017.1290073. Epub 2017 Feb 28.

PMID:
28277119
48.

Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity.

Travelli C, Aprile S, Rahimian R, Grolla AA, Rogati F, Bertolotti M, Malagnino F, di Paola R, Impellizzeri D, Fusco R, Mercalli V, Massarotti A, Stortini G, Terrazzino S, Del Grosso E, Fakhfouri G, Troiani MP, Alisi MA, Grosa G, Sorba G, Canonico PL, Orsomando G, Cuzzocrea S, Genazzani AA, Galli U, Tron GC.

J Med Chem. 2017 Mar 9;60(5):1768-1792. doi: 10.1021/acs.jmedchem.6b01392. Epub 2017 Feb 22.

PMID:
28165742
49.

A novel gain-of-function mutation in ORAI1 causes late-onset tubular aggregate myopathy and congenital miosis.

Garibaldi M, Fattori F, Riva B, Labasse C, Brochier G, Ottaviani P, Sacconi S, Vizzaccaro E, Laschena F, Romero NB, Genazzani A, Bertini E, Antonini G.

Clin Genet. 2017 May;91(5):780-786. doi: 10.1111/cge.12888. Epub 2016 Nov 23.

PMID:
27882542
50.

Celecoxib inhibits proliferation and survival of chronic myelogeous leukemia (CML) cells via AMPK-dependent regulation of β-catenin and mTORC1/2.

Riva B, De Dominici M, Gnemmi I, Mariani SA, Minassi A, Minieri V, Salomoni P, Canonico PL, Genazzani AA, Calabretta B, Condorelli F.

Oncotarget. 2016 Dec 6;7(49):81555-81570. doi: 10.18632/oncotarget.13146.

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