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Items: 6


Noncanonical STAT1 phosphorylation expands its transcriptional activity into promoting LPS-induced IL-6 and IL-12p40 production.

Metwally H, Tanaka T, Li S, Parajuli G, Kang S, Hanieh H, Hashimoto S, Chalise JP, Gemechu Y, Standley DM, Kishimoto T.

Sci Signal. 2020 Mar 24;13(624). pii: eaay0574. doi: 10.1126/scisignal.aay0574.


Feedback regulation of Arid5a and Ppar-γ2 maintains adipose tissue homeostasis.

Chalise JP, Hashimoto S, Parajuli G, Kang S, Singh SK, Gemechu Y, Metwally H, Nyati KK, Dubey PK, Zaman MM, Nagahama Y, Hamza H, Masuda K, Kishimoto T.

Proc Natl Acad Sci U S A. 2019 Jul 23;116(30):15128-15133. doi: 10.1073/pnas.1906712116. Epub 2019 Jul 9.


Humanized cereblon mice revealed two distinct therapeutic pathways of immunomodulatory drugs.

Gemechu Y, Millrine D, Hashimoto S, Prakash J, Sanchenkova K, Metwally H, Gyanu P, Kang S, Kishimoto T.

Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):11802-11807. doi: 10.1073/pnas.1814446115. Epub 2018 Oct 29.


Rabex-5 is a lenalidomide target molecule that negatively regulates TLR-induced type 1 IFN production.

Millrine D, Tei M, Gemechu Y, Kishimoto T.

Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):10625-30. doi: 10.1073/pnas.1611751113. Epub 2016 Sep 6.


Factors associated with exclusive breastfeeding practices among mothers in dubti town, afar regional state, northeast Ethiopia: a community based cross-sectional study.

Liben ML, Gemechu YB, Adugnew M, Asrade A, Adamie B, Gebremedin E, Melak Y.

Int Breastfeed J. 2016 Mar 18;11:4. doi: 10.1186/s13006-016-0064-y. eCollection 2016.


Immunomodulatory drugs inhibit TLR4-induced type-1 interferon production independently of Cereblon via suppression of the TRIF/IRF3 pathway.

Millrine D, Miyata H, Tei M, Dubey P, Nyati K, Nakahama T, Gemechu Y, Ripley B, Kishimoto T.

Int Immunol. 2016 Jun;28(6):307-15. doi: 10.1093/intimm/dxw005. Epub 2016 Feb 10.


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