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Items: 1 to 50 of 94

1.

Mitochondrial Morphology, Function and Homeostasis Are Impaired by Expression of an N-terminal Calpain Cleavage Fragment of Ataxin-3.

Harmuth T, Prell-Schicker C, Weber JJ, Gellerich F, Funke C, Drießen S, Magg JCD, Krebiehl G, Wolburg H, Hayer SN, Hauser S, Krüger R, Schöls L, Riess O, Hübener-Schmid J.

Front Mol Neurosci. 2018 Oct 10;11:368. doi: 10.3389/fnmol.2018.00368. eCollection 2018.

2.

Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology.

Szibor M, Dhandapani PK, Dufour E, Holmström KM, Zhuang Y, Salwig I, Wittig I, Heidler J, Gizatullina Z, Gainutdinov T; German Mouse Clinic Consortium, Fuchs H, Gailus-Durner V, de Angelis MH, Nandania J, Velagapudi V, Wietelmann A, Rustin P, Gellerich FN, Jacobs HT, Braun T.

Dis Model Mech. 2017 Feb 1;10(2):163-171. doi: 10.1242/dmm.027839. Epub 2016 Dec 14.

3.

Activation of Mitochondrial Complex II-Dependent Respiration Is Beneficial for α-Synucleinopathies.

Fröhlich C, Zschiebsch K, Gröger V, Paarmann K, Steffen J, Thurm C, Schropp EM, Brüning T, Gellerich F, Radloff M, Schwabe R, Lachmann I, Krohn M, Ibrahim S, Pahnke J.

Mol Neurobiol. 2016 Sep;53(7):4728-44. doi: 10.1007/s12035-015-9399-4. Epub 2015 Aug 29.

4.

Knockout of cyclophilin D in Ppif⁻/⁻ mice increases stability of brain mitochondria against Ca²⁺ stress.

Gainutdinov T, Molkentin JD, Siemen D, Ziemer M, Debska-Vielhaber G, Vielhaber S, Gizatullina Z, Orynbayeva Z, Gellerich FN.

Arch Biochem Biophys. 2015 Aug 1;579:40-6. doi: 10.1016/j.abb.2015.05.009. Epub 2015 May 29.

PMID:
26032335
5.

Mitochondrial dysfunction in primary human fibroblasts triggers an adaptive cell survival program that requires AMPK-α.

Distelmaier F, Valsecchi F, Liemburg-Apers DC, Lebiedzinska M, Rodenburg RJ, Heil S, Keijer J, Fransen J, Imamura H, Danhauser K, Seibt A, Viollet B, Gellerich FN, Smeitink JA, Wieckowski MR, Willems PH, Koopman WJ.

Biochim Biophys Acta. 2015 Mar;1852(3):529-40. doi: 10.1016/j.bbadis.2014.12.012. Epub 2014 Dec 20.

6.

6-Hydroxydopamine impairs mitochondrial function in the rat model of Parkinson's disease: respirometric, histological, and behavioral analyses.

Kupsch A, Schmidt W, Gizatullina Z, Debska-Vielhaber G, Voges J, Striggow F, Panther P, Schwegler H, Heinze HJ, Vielhaber S, Gellerich FN.

J Neural Transm (Vienna). 2014 Oct;121(10):1245-57. doi: 10.1007/s00702-014-1185-3. Epub 2014 Mar 14.

PMID:
24627045
7.

The control of brain mitochondrial energization by cytosolic calcium: the mitochondrial gas pedal.

Gellerich FN, Gizatullina Z, Gainutdinov T, Muth K, Seppet E, Orynbayeva Z, Vielhaber S.

IUBMB Life. 2013 Mar;65(3):180-90. doi: 10.1002/iub.1131. Epub 2013 Feb 8. Review.

8.

Dilation of human atria: increased diffusion restrictions for ADP, overexpression of hexokinase 2 and its coupling to oxidative phosphorylation in cardiomyocytes.

Roosimaa M, Põdramägi T, Kadaja L, Ruusalepp A, Paju K, Puhke R, Eimre M, Orlova E, Piirsoo A, Peet N, Gellerich FN, Seppet E.

Mitochondrion. 2013 Sep;13(5):399-409. doi: 10.1016/j.mito.2012.12.005. Epub 2012 Dec 23.

PMID:
23268198
9.

Oxygen glucose deprivation causes mitochondrial dysfunction in cultivated rat hippocampal slices: protective effects of CsA, its immunosuppressive congener [D-Ser](8)CsA, the novel non-immunosuppressive cyclosporin derivative Cs9, and the NMDA receptor antagonist MK 801.

Trumbeckaite S, Gizatullina Z, Arandarcikaite O, Röhnert P, Vielhaber S, Malesevic M, Fischer G, Seppet E, Striggow F, Gellerich FN.

Mitochondrion. 2013 Sep;13(5):539-47. doi: 10.1016/j.mito.2012.07.110. Epub 2012 Jul 21.

PMID:
22824458
10.

Complex effects of 17β-estradiol on mitochondrial function.

Thiede A, Gellerich FN, Schönfeld P, Siemen D.

Biochim Biophys Acta. 2012 Oct;1817(10):1747-53. doi: 10.1016/j.bbabio.2012.02.034. Epub 2012 Mar 5.

11.

Cytosolic Ca2+ regulates the energization of isolated brain mitochondria by formation of pyruvate through the malate-aspartate shuttle.

Gellerich FN, Gizatullina Z, Trumbekaite S, Korzeniewski B, Gaynutdinov T, Seppet E, Vielhaber S, Heinze HJ, Striggow F.

Biochem J. 2012 May 1;443(3):747-55. doi: 10.1042/BJ20110765.

PMID:
22295911
12.

Impaired oxidative phosphorylation in overtrained rat myocardium.

Kadaja L, Eimre M, Paju K, Roosimaa M, Põdramägi T, Kaasik P, Pehme A, Orlova E, Mudist M, Peet N, Piirsoo A, Seene T, Gellerich FN, Seppet EK.

Exp Clin Cardiol. 2010 Winter;15(4):e116-27.

13.

Effects of cyclosporine A and its immunosuppressive or non-immunosuppressive derivatives [D-Ser]8-CsA and Cs9 on mitochondria from different brain regions.

Gizatullina ZZ, Gaynutdinov TM, Svoboda H, Jerzembek D, Knabe A, Vielhaber S, Malesevic M, Heinze HJ, Fischer G, Striggow F, Gellerich FN.

Mitochondrion. 2011 May;11(3):421-9. doi: 10.1016/j.mito.2010.12.012. Epub 2010 Dec 16.

PMID:
21167961
14.

Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1.

Krebiehl G, Ruckerbauer S, Burbulla LF, Kieper N, Maurer B, Waak J, Wolburg H, Gizatullina Z, Gellerich FN, Woitalla D, Riess O, Kahle PJ, Proikas-Cezanne T, Krüger R.

PLoS One. 2010 Feb 23;5(2):e9367. doi: 10.1371/journal.pone.0009367.

15.

The regulation of OXPHOS by extramitochondrial calcium.

Gellerich FN, Gizatullina Z, Trumbeckaite S, Nguyen HP, Pallas T, Arandarcikaite O, Vielhaber S, Seppet E, Striggow F.

Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):1018-27. doi: 10.1016/j.bbabio.2010.02.005. Epub 2010 Feb 6. Review.

16.

Extramitochondrial Ca2+ in the nanomolar range regulates glutamate-dependent oxidative phosphorylation on demand.

Gellerich FN, Gizatullina Z, Arandarcikaite O, Jerzembek D, Vielhaber S, Seppet E, Striggow F.

PLoS One. 2009 Dec 9;4(12):e8181. doi: 10.1371/journal.pone.0008181.

17.

Mitochondria and energetic depression in cell pathophysiology.

Seppet E, Gruno M, Peetsalu A, Gizatullina Z, Nguyen HP, Vielhaber S, Wussling MH, Trumbeckaite S, Arandarcikaite O, Jerzembeck D, Sonnabend M, Jegorov K, Zierz S, Striggow F, Gellerich FN.

Int J Mol Sci. 2009 May 19;10(5):2252-303. doi: 10.3390/ijms10052252. Review.

18.

Impaired regulation of brain mitochondria by extramitochondrial Ca2+ in transgenic Huntington disease rats.

Gellerich FN, Gizatullina Z, Nguyen HP, Trumbeckaite S, Vielhaber S, Seppet E, Zierz S, Landwehrmeyer B, Riess O, von Hörsten S, Striggow F.

J Biol Chem. 2008 Nov 7;283(45):30715-24. doi: 10.1074/jbc.M709555200. Epub 2008 Jul 7.

19.

Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells.

Kuznetsov AV, Veksler V, Gellerich FN, Saks V, Margreiter R, Kunz WS.

Nat Protoc. 2008;3(6):965-76. doi: 10.1038/nprot.2008.61.

PMID:
18536644
20.

Myopathy as a first symptom of Huntington's disease in a Marathon runner.

Kosinski CM, Schlangen C, Gellerich FN, Gizatullina Z, Deschauer M, Schiefer J, Young AB, Landwehrmeyer GB, Toyka KV, Sellhaus B, Lindenberg KS.

Mov Disord. 2007 Aug 15;22(11):1637-40.

PMID:
17534945
21.

Mitochondrial OXPHOS functions in R1H rhabdomyosarcoma and skeletal muscles of the rat.

Kuhnt T, Pelz T, Qu X, Hänsgen G, Dunst J, Gellerich FN.

Neurochem Res. 2007 Jun;32(6):973-80. Epub 2007 Feb 2.

PMID:
17273927
22.

Glutathione depletion in antioxidant defense of differentiated NT2-LHON cybrids.

Schoeler S, Winkler-Stuck K, Szibor R, Haroon MF, Gellerich FN, Chamaon K, Mawrin C, Kirches E.

Neurobiol Dis. 2007 Mar;25(3):536-44. Epub 2006 Dec 12.

PMID:
17169568
23.

Molecular and biochemical investigations in fumarase deficiency.

Deschauer M, Gizatullina Z, Schulze A, Pritsch M, Knöppel C, Knape M, Zierz S, Gellerich FN.

Mol Genet Metab. 2006 Jun;88(2):146-52. Epub 2006 Feb 28.

PMID:
16510303
24.

Low stability of Huntington muscle mitochondria against Ca2+ in R6/2 mice.

Gizatullina ZZ, Lindenberg KS, Harjes P, Chen Y, Kosinski CM, Landwehrmeyer BG, Ludolph AC, Striggow F, Zierz S, Gellerich FN.

Ann Neurol. 2006 Feb;59(2):407-11.

PMID:
16437579
25.

Intracellular energetic units in healthy and diseased hearts.

Seppet EK, Eimre M, Anmann T, Seppet E, Peet N, Käämbre T, Paju K, Piirsoo A, Kuznetsov AV, Vendelin M, Gellerich FN, Zierz S, Saks VA.

Exp Clin Cardiol. 2005 Fall;10(3):173-83.

26.

The problem of interlab variation in methods for mitochondrial disease diagnosis: enzymatic measurement of respiratory chain complexes.

Gellerich FN, Mayr JA, Reuter S, Sperl W, Zierz S.

Mitochondrion. 2004 Sep;4(5-6):427-39. Epub 2004 Oct 18.

PMID:
16120404
27.

Mitochondrial changes in skeletal muscle in amyotrophic lateral sclerosis and other neurogenic atrophies.

Krasnianski A, Deschauer M, Neudecker S, Gellerich FN, Müller T, Schoser BG, Krasnianski M, Zierz S.

Brain. 2005 Aug;128(Pt 8):1870-6. Epub 2005 May 18.

PMID:
15901649
28.

Mitochondrial DNA deletions sensitize cells to apoptosis at low heteroplasmy levels.

Schoeler S, Szibor R, Gellerich FN, Wartmann T, Mawrin C, Dietzmann K, Kirches E.

Biochem Biophys Res Commun. 2005 Jun 24;332(1):43-9.

PMID:
15896297
29.

Compartmentation of energy metabolism in atrial myocardium of patients undergoing cardiac surgery.

Seppet E, Eimre M, Peet N, Paju K, Orlova E, Ress M, Kõvask S, Piirsoo A, Saks VA, Gellerich FN, Zierz S, Seppet EK.

Mol Cell Biochem. 2005 Feb;270(1-2):49-61.

PMID:
15792353
30.

Elevated creatine kinase activity in primary hepatocellular carcinoma.

Meffert G, Gellerich FN, Margreiter R, Wyss M.

BMC Gastroenterol. 2005 Mar 5;5:9.

31.

Effects of extramitochondrial ADP on permeability transition of mouse liver mitochondria.

Gizatullina ZZ, Chen Y, Zierz S, Gellerich FN.

Biochim Biophys Acta. 2005 Jan 7;1706(1-2):98-104.

32.

Mitochondrial function in turkey skeletal muscle--impact on meat quality.

Opalka JR, Wicke M, Gellerich FN, Schmidt R, Rosner F, Zierz S, von Lengerken G.

Br Poult Sci. 2004 Jun;45(3):367-79.

PMID:
15327123
33.

A case of childhood Pompe disease demonstrating phenotypic variability of p.Asp645Asn.

Kroos MA, Kirschner J, Gellerich FN, Hermans MM, Van Der Ploeg AT, Reuser AJ, Korinthenberg R.

Neuromuscul Disord. 2004 Jun;14(6):371-4.

PMID:
15145338
34.

Energetic depression caused by mitochondrial dysfunction.

Gellerich FN, Trumbeckaite S, Müller T, Deschauer M, Chen Y, Gizatullina Z, Zierz S.

Mol Cell Biochem. 2004 Jan-Feb;256-257(1-2):391-405. Review.

PMID:
14977198
35.

Inhibitors of SERCA and mitochondrial Ca-uniporter decrease velocity of calcium waves in rat cardiomyocytes.

Landgraf G, Gellerich FN, Wussling MH.

Mol Cell Biochem. 2004 Jan-Feb;256-257(1-2):379-86.

PMID:
14977196
36.

Different sensitivities of CPT I and CPT II for inhibition by l-aminocarnitine in human skeletal muscle.

Traufeller K, Gellerich FN, Zierz S.

Biochim Biophys Acta. 2004 Feb 15;1608(2-3):149-54.

37.

A novel water-soluble and cell-permeable calpain inhibitor protects myocardial and mitochondrial function in postischemic reperfusion.

Neuhof C, Götte O, Trumbeckaite S, Attenberger M, Kuzkaya N, Gellerich F, Möller A, Lubisch W, Speth M, Tillmanns H, Neuhof H.

Biol Chem. 2003 Dec;384(12):1597-603.

PMID:
14719802
38.

Cryopreservation of mitochondria and mitochondrial function in cardiac and skeletal muscle fibers.

Kuznetsov AV, Kunz WS, Saks V, Usson Y, Mazat JP, Letellier T, Gellerich FN, Margreiter R.

Anal Biochem. 2003 Aug 15;319(2):296-303.

PMID:
12871725
39.

Calpain inhibitor (BSF 409425) diminishes ischemia/reperfusion-induced damage of rabbit heart mitochondria.

Trumbeckaite S, Neuhof C, Zierz S, Gellerich FN.

Biochem Pharmacol. 2003 Mar 1;65(5):911-6.

PMID:
12628497
40.

Increased metabolic muscle fatigue is caused by some but not all mitochondrial mutations.

Schulte-Mattler WJ, Müller T, Deschauer M, Gellerich FN, Iaizzo PA, Zierz S.

Arch Neurol. 2003 Jan;60(1):50-8.

PMID:
12533088
41.

Energetic depression caused by mitochondrial dysfunction.

Gellerich FN, Trumbeckaite S, Chen Y, Deschauer M, M ller T, Zierz S.

Eur Cytokine Netw. 2002 Oct-Dec;13(4):395-7. Review.

42.

Dysfunction of mitochondrial respiratory chain complex I in human failing myocardium is not due to disturbed mitochondrial gene expression.

Scheubel RJ, Tostlebe M, Simm A, Rohrbach S, Prondzinsky R, Gellerich FN, Silber RE, Holtz J.

J Am Coll Cardiol. 2002 Dec 18;40(12):2174-81.

43.

Mitochondrial dysfunction in sepsis: evidence from bacteraemic baboons and endotoxaemic rabbits.

Gellerich FN, Trumbeckaite S, Opalka JR, Gellerich JF, Chen Y, Neuhof C, Redl H, Werdan K, Zierz S.

Biosci Rep. 2002 Feb;22(1):99-113. Review.

PMID:
12418553
44.
45.

The quantitation of ADP diffusion gradients across the outer membrane of heart mitochondria in the presence of macromolecules.

Gellerich FN, Laterveer FD, Zierz S, Nicolay K.

Biochim Biophys Acta. 2002 Apr 22;1554(1-2):48-56.

46.

Effect of the new matrix metalloproteinase inhibitor RO-28-2653 on mitochondrial function.

Opalka JR, Gellerich FN, Kling L, Müller-Beckmann B, Zierz S.

Biochem Pharmacol. 2002 Feb 15;63(4):725-32.

PMID:
11992641
47.

Age and sex dependency of carnitine concentration in human serum and skeletal muscle.

Opalka JR, Gellerich FN, Zierz S.

Clin Chem. 2001 Dec;47(12):2150-3. No abstract available.

48.

Lack of dystrophin is associated with altered integration of the mitochondria and ATPases in slow-twitch muscle cells of MDX mice.

Braun U, Paju K, Eimre M, Seppet E, Orlova E, Kadaja L, Trumbeckaite S, Gellerich FN, Zierz S, Jockusch H, Seppet EK.

Biochim Biophys Acta. 2001 Jun 1;1505(2-3):258-70.

49.

Different sensitivity of rabbit heart and skeletal muscle to endotoxin-induced impairment of mitochondrial function.

Trumbeckaite S, Opalka JR, Neuhof C, Zierz S, Gellerich FN.

Eur J Biochem. 2001 Mar;268(5):1422-9.

50.

Higher proportion of mitochondrial A3243G mutation in blood than in skeletal muscle in a patient with cardiomyopathy and hearing loss.

Deschauer M, Neudecker S, Müller T, Gellerich FN, Zierz S.

Mol Genet Metab. 2000 Jul;70(3):235-7.

PMID:
10924279

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