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Items: 50

1.

AcrAB-TolC Inhibition by Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers Restores Antibiotic Activity in Vitro and in Vivo.

Sturge CR, Felder-Scott CF, Pifer R, Pybus C, Jain R, Geller BL, Greenberg DE.

ACS Infect Dis. 2019 Aug 9;5(8):1446-1455. doi: 10.1021/acsinfecdis.9b00123. Epub 2019 Jun 11.

PMID:
31119935
2.

Morpholino oligomers tested in vitro, in biofilm and in vivo against multidrug-resistant Klebsiella pneumoniae.

Geller BL, Li L, Martinez F, Sully E, Sturge CR, Daly SM, Pybus C, Greenberg DE.

J Antimicrob Chemother. 2018 Jun 1;73(6):1611-1619. doi: 10.1093/jac/dky058.

3.

Antisense Inhibitors Retain Activity in Pulmonary Models of Burkholderia Infection.

Daly SM, Sturge CR, Marshall-Batty KR, Felder-Scott CF, Jain R, Geller BL, Greenberg DE.

ACS Infect Dis. 2018 May 11;4(5):806-814. doi: 10.1021/acsinfecdis.7b00235. Epub 2018 Mar 1.

4.

MCR-1 Inhibition with Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers Restores Sensitivity to Polymyxin in Escherichia coli.

Daly SM, Sturge CR, Felder-Scott CF, Geller BL, Greenberg DE.

MBio. 2017 Nov 7;8(6). pii: e01315-17. doi: 10.1128/mBio.01315-17.

5.

Inhibition of Pseudomonas aeruginosa by Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers.

Howard JJ, Sturge CR, Moustafa DA, Daly SM, Marshall-Batty KR, Felder CF, Zamora D, Yabe-Gill M, Labandeira-Rey M, Bailey SM, Wong M, Goldberg JB, Geller BL, Greenberg DE.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e01938-16. doi: 10.1128/AAC.01938-16. Print 2017 Apr.

6.

Peptide-conjugated phosphorodiamidate morpholino oligomer (PPMO) restores carbapenem susceptibility to NDM-1-positive pathogens in vitro and in vivo.

Sully EK, Geller BL, Li L, Moody CM, Bailey SM, Moore AL, Wong M, Nordmann P, Daly SM, Sturge CR, Greenberg DE.

J Antimicrob Chemother. 2017 Mar 1;72(3):782-790. doi: 10.1093/jac/dkw476.

7.

Antimicrobial activity of antisense peptide-peptide nucleic acid conjugates against non-typeable Haemophilus influenzae in planktonic and biofilm forms.

Otsuka T, Brauer AL, Kirkham C, Sully EK, Pettigrew MM, Kong Y, Geller BL, Murphy TF.

J Antimicrob Chemother. 2017 Jan;72(1):137-144. Epub 2016 Sep 28.

8.

Antisense antimicrobial therapeutics.

Sully EK, Geller BL.

Curr Opin Microbiol. 2016 Oct;33:47-55. doi: 10.1016/j.mib.2016.05.017. Epub 2016 Jun 29. Review.

9.

Simultaneous Host-Pathogen Transcriptome Analysis during Granulibacter bethesdensis Infection of Neutrophils from Healthy Subjects and Patients with Chronic Granulomatous Disease.

Greenberg DE, Sturdevant DE, Marshall-Batty KR, Chu J, Pettinato AM, Virtaneva K, Lane J, Geller BL, Porcella SF, Gallin JI, Holland SM, Zarember KA.

Infect Immun. 2015 Nov;83(11):4277-92. doi: 10.1128/IAI.00778-15. Epub 2015 Aug 17.

10.

Peptide-conjugated phosphorodiamidate morpholino oligomers: a new strategy for tackling antibiotic resistance.

Geller BL, Greenberg DE.

Ther Deliv. 2014 Mar;5(3):243-5. doi: 10.4155/tde.13.145. No abstract available.

PMID:
24592949
11.

Gene-silencing antisense oligomers inhibit acinetobacter growth in vitro and in vivo.

Geller BL, Marshall-Batty K, Schnell FJ, McKnight MM, Iversen PL, Greenberg DE.

J Infect Dis. 2013 Nov 15;208(10):1553-60. doi: 10.1093/infdis/jit460. Epub 2013 Oct 14.

12.

A Novel Lactococcal Vaccine Expressing a Peptide from the M2 Antigen of H5N2 Highly Pathogenic Avian Influenza A Virus Prolongs Survival of Vaccinated Chickens.

Reese KA, Lupfer C, Johnson RC, Mitev GM, Mullen VM, Geller BL, Pastey M.

Vet Med Int. 2013;2013:316926. doi: 10.1155/2013/316926. Epub 2013 May 22.

13.

Bacterial resistance to antisense peptide phosphorodiamidate morpholino oligomers.

Puckett SE, Reese KA, Mitev GM, Mullen V, Johnson RC, Pomraning KR, Mellbye BL, Tilley LD, Iversen PL, Freitag M, Geller BL.

Antimicrob Agents Chemother. 2012 Dec;56(12):6147-53. doi: 10.1128/AAC.00850-12. Epub 2012 Sep 17.

14.

Peptide conjugated phosphorodiamidate morpholino oligomers increase survival of mice challenged with Ames Bacillus anthracis.

Panchal RG, Geller BL, Mellbye B, Lane D, Iversen PL, Bavari S.

Nucleic Acid Ther. 2012 Oct;22(5):316-22. doi: 10.1089/nat.2012.0362. Epub 2012 Sep 14.

15.

Antisense phosphorodiamidate morpholino oligomers targeted to an essential gene inhibit Burkholderia cepacia complex.

Greenberg DE, Marshall-Batty KR, Brinster LR, Zarember KA, Shaw PA, Mellbye BL, Iversen PL, Holland SM, Geller BL.

J Infect Dis. 2010 Jun 15;201(12):1822-30. doi: 10.1086/652807.

16.

Cationic phosphorodiamidate morpholino oligomers efficiently prevent growth of Escherichia coli in vitro and in vivo.

Mellbye BL, Weller DD, Hassinger JN, Reeves MD, Lovejoy CE, Iversen PL, Geller BL.

J Antimicrob Chemother. 2010 Jan;65(1):98-106. doi: 10.1093/jac/dkp392.

PMID:
19884121
17.

Inhibition of intracellular growth of Salmonella enterica serovar Typhimurium in tissue culture by antisense peptide-phosphorodiamidate morpholino oligomer.

Mitev GM, Mellbye BL, Iversen PL, Geller BL.

Antimicrob Agents Chemother. 2009 Sep;53(9):3700-4. doi: 10.1128/AAC.00099-09. Epub 2009 Jul 6.

18.

Variations in amino acid composition of antisense peptide-phosphorodiamidate morpholino oligomer affect potency against Escherichia coli in vitro and in vivo.

Mellbye BL, Puckett SE, Tilley LD, Iversen PL, Geller BL.

Antimicrob Agents Chemother. 2009 Feb;53(2):525-30. doi: 10.1128/AAC.00917-08. Epub 2008 Nov 17.

19.

Antisense peptide-phosphorodiamidate morpholino oligomer conjugate: dose-response in mice infected with Escherichia coli.

Tilley LD, Mellbye BL, Puckett SE, Iversen PL, Geller BL.

J Antimicrob Chemother. 2007 Jan;59(1):66-73. Epub 2006 Oct 31.

PMID:
17079242
20.

Subcellular location of phage infection protein (Pip) in Lactococcus lactis.

Mooney DT, Jann M, Geller BL.

Can J Microbiol. 2006 Jul;52(7):664-72.

PMID:
16917523
21.
22.

Antisense phosphorodiamidate morpholino oligomer inhibits viability of Escherichia coli in pure culture and in mouse peritonitis.

Geller BL, Deere J, Tilley L, Iversen PL.

J Antimicrob Chemother. 2005 Jun;55(6):983-8. Epub 2005 May 4.

PMID:
15872045
23.

Antibacterial antisense.

Geller BL.

Curr Opin Mol Ther. 2005 Apr;7(2):109-13. Review.

PMID:
15844617
24.

Lactococcal 936-species phage attachment to surface of Lactococcus lactis.

Geller BL, Ngo HT, Mooney DT, Su P, Dunn N.

J Dairy Sci. 2005 Mar;88(3):900-7.

25.
27.

Differential activation of the NF-kappaB-like factors Relish and Dif in Drosophila melanogaster by fungi and Gram-positive bacteria.

Hedengren-Olcott M, Olcott MC, Mooney DT, Ekengren S, Geller BL, Taylor BJ.

J Biol Chem. 2004 May 14;279(20):21121-7. Epub 2004 Feb 25.

28.

Inhibition of gene expression in Escherichia coli by antisense phosphorodiamidate morpholino oligomers.

Geller BL, Deere JD, Stein DA, Kroeker AD, Moulton HM, Iversen PL.

Antimicrob Agents Chemother. 2003 Oct;47(10):3233-9.

29.

Surface expression of the conserved C repeat region of streptococcal M6 protein within the Pip bacteriophage receptor of Lactococcus lactis.

Geller BL, Wade N, Gilberts TD, Hruby DE, Johanson R, Topisirovic L.

Appl Environ Microbiol. 2001 Dec;67(12):5370-6.

30.

Molecular characterization of a new abortive infection system (AbiU) from Lactococcus lactis LL51-1.

Dai G, Su P, Allison GE, Geller BL, Zhu P, Kim WS, Dunn NW.

Appl Environ Microbiol. 2001 Nov;67(11):5225-32.

32.

Characterization of a cloned gene (pip) from lactococcus lactis required for phage infection.

Babu KS, Spence WS, Monteville MR, Geller BL.

Dev Biol Stand. 1995;85:569-75. No abstract available.

PMID:
8586234
33.
34.

Isolation and characterization of sulfite mutants of Saccharomyces cerevisiae.

Xu X, Wightman JD, Geller BL, Avram D, Bakalinsky AT.

Curr Genet. 1994 Jun;25(6):488-96.

PMID:
8082198
35.

Cloning of a chromosomal gene required for phage infection of Lactococcus lactis subsp. lactis C2.

Geller BL, Ivey RG, Trempy JE, Hettinger-Smith B.

J Bacteriol. 1993 Sep;175(17):5510-9.

36.

A membrane protein is required for bacteriophage c2 infection of Lactococcus lactis subsp. lactis C2.

Valyasevi R, Sandine WE, Geller BL.

J Bacteriol. 1991 Oct;173(19):6095-100.

37.
39.
41.
42.

The amino terminus of the yeast F1-ATPase beta-subunit precursor functions as a mitochondrial import signal.

Emr SD, Vassarotti A, Garrett J, Geller BL, Takeda M, Douglas MG.

J Cell Biol. 1986 Feb;102(2):523-33.

43.

M13 procoat inserts into liposomes in the absence of other membrane proteins.

Geller BL, Wickner W.

J Biol Chem. 1985 Oct 25;260(24):13281-5.

44.
45.

Subcellular distribution of superoxide dismutases in rat liver.

Geller BL, Winge DR.

Methods Enzymol. 1984;105:105-14. No abstract available.

PMID:
6328174
46.

A method for distinguishing Cu,Zn- and Mn-containing superoxide dismutases.

Geller BL, Winge DR.

Anal Biochem. 1983 Jan;128(1):86-92.

PMID:
6846803
47.

Rat liver Cu,Zn-superoxide dismutase. Subcellular location in lysosomes.

Geller BL, Winge DR.

J Biol Chem. 1982 Aug 10;257(15):8945-52.

48.

Metal binding sites of rat liver Cu-thionein.

Geller BL, Winge DR.

Arch Biochem Biophys. 1982 Jan;213(1):109-17. No abstract available.

PMID:
6277248
49.

Isolation of copper thionein from rat liver.

Winge DR, Geller BL, Garvey J.

Arch Biochem Biophys. 1981 Apr 15;208(1):160-6. No abstract available.

PMID:
7259175
50.

Antimalarial properties of a variety of substituted p-sulfamoylphenylazo compounds.

Harmon RE, Geller BL, Gupta SK, Herbert MH, Chitharanjan D.

J Pharm Sci. 1970 Jul;59(7):1031-3. No abstract available.

PMID:
5428076

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