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Items: 12

1.

PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy.

Ruf S, Heberle AM, Langelaar-Makkinje M, Gelino S, Wilkinson D, Gerbeth C, Schwarz JJ, Holzwarth B, Warscheid B, Meisinger C, van Vugt MA, Baumeister R, Hansen M, Thedieck K.

Autophagy. 2017 Mar 4;13(3):486-505. doi: 10.1080/15548627.2016.1263781. Epub 2017 Jan 19.

2.

Correction: Intestinal Autophagy Improves Healthspan and Longevity in C. elegans During Dietary Restriction.

Gelino S, Chang JT, Kumsta C, She X, Davis A, Nguyen C, Panowski S, Hansen M.

PLoS Genet. 2016 Aug 16;12(8):e1006271. doi: 10.1371/journal.pgen.1006271. eCollection 2016 Aug.

3.

Intestinal Autophagy Improves Healthspan and Longevity in C. elegans during Dietary Restriction.

Gelino S, Chang JT, Kumsta C, She X, Davis A, Nguyen C, Panowski S, Hansen M.

PLoS Genet. 2016 Jul 14;12(7):e1006135. doi: 10.1371/journal.pgen.1006135. eCollection 2016 Jul. Erratum in: PLoS Genet. 2016 Aug;12(8):e1006271.

4.

C. elegans S6K Mutants Require a Creatine-Kinase-like Effector for Lifespan Extension.

McQuary PR, Liao CY, Chang JT, Kumsta C, She X, Davis A, Chu CC, Gelino S, Gomez-Amaro RL, Petrascheck M, Brill LM, Ladiges WC, Kennedy BK, Hansen M.

Cell Rep. 2016 Mar 8;14(9):2059-2067. doi: 10.1016/j.celrep.2016.02.012. Epub 2016 Feb 25.

5.

Integrin-linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF-1.

Kumsta C, Ching TT, Nishimura M, Davis AE, Gelino S, Catan HH, Yu X, Chu CC, Ong B, Panowski SH, Baird N, Bodmer R, Hsu AL, Hansen M.

Aging Cell. 2014 Jun;13(3):419-30. doi: 10.1111/acel.12189. Epub 2014 Jan 9.

6.

The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans.

Lapierre LR, De Magalhaes Filho CD, McQuary PR, Chu CC, Visvikis O, Chang JT, Gelino S, Ong B, Davis AE, Irazoqui JE, Dillin A, Hansen M.

Nat Commun. 2013;4:2267. doi: 10.1038/ncomms3267.

7.

Autophagy - An Emerging Anti-Aging Mechanism.

Gelino S, Hansen M.

J Clin Exp Pathol. 2012 Jul 12;Suppl 4. pii: 006.

8.

Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. elegans.

Schiavi A, Torgovnick A, Kell A, Megalou E, Castelein N, Guccini I, Marzocchella L, Gelino S, Hansen M, Malisan F, Condò I, Bei R, Rea SL, Braeckman BP, Tavernarakis N, Testi R, Ventura N.

Exp Gerontol. 2013 Feb;48(2):191-201. doi: 10.1016/j.exger.2012.12.002. Epub 2012 Dec 13. Erratum in: Exp Gerontol. 2013 Sep;48(9):1001.

9.

Testing predictions of the oxidative stress hypothesis of aging using a novel invertebrate model of longevity: the giant clam (Tridacna derasa).

Ungvari Z, Csiszar A, Sosnowska D, Philipp EE, Campbell CM, McQuary PR, Chow TT, Coelho M, Didier ES, Gelino S, Holmbeck MA, Kim I, Levy E, Sonntag WE, Whitby PW, Austad SN, Ridgway I.

J Gerontol A Biol Sci Med Sci. 2013 Apr;68(4):359-67. doi: 10.1093/gerona/gls159. Epub 2012 Aug 17.

10.

Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans.

Lapierre LR, Gelino S, Meléndez A, Hansen M.

Curr Biol. 2011 Sep 27;21(18):1507-14. doi: 10.1016/j.cub.2011.07.042. Epub 2011 Sep 8.

11.

Extreme longevity is associated with increased resistance to oxidative stress in Arctica islandica, the longest-living non-colonial animal.

Ungvari Z, Ridgway I, Philipp EE, Campbell CM, McQuary P, Chow T, Coelho M, Didier ES, Gelino S, Holmbeck MA, Kim I, Levy E, Sosnowska D, Sonntag WE, Austad SN, Csiszar A.

J Gerontol A Biol Sci Med Sci. 2011 Jul;66(7):741-50. doi: 10.1093/gerona/glr044. Epub 2011 Apr 12.

12.

Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy.

Egan DF, Shackelford DB, Mihaylova MM, Gelino S, Kohnz RA, Mair W, Vasquez DS, Joshi A, Gwinn DM, Taylor R, Asara JM, Fitzpatrick J, Dillin A, Viollet B, Kundu M, Hansen M, Shaw RJ.

Science. 2011 Jan 28;331(6016):456-61. doi: 10.1126/science.1196371. Epub 2010 Dec 23.

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