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Items: 1 to 50 of 124

1.

Conserved role for Ataxin-2 in mediating endoplasmic reticulum dynamics.

Del Castillo U, Gnazzo MM, Sorensen Turpin CG, Nguyen KCQ, Semaya E, Lam Y, de Cruz MA, Bembenek JN, Hall DH, Riggs B, Gelfand VI, Skop AR.

Traffic. 2019 Jun;20(6):436-447. doi: 10.1111/tra.12647. Epub 2019 May 8.

PMID:
30989774
2.

Repurposing Kinetochore Microtubule Attachment Machinery in Neurodevelopment.

Norkett R, Lu W, Gelfand VI.

Dev Cell. 2019 Mar 25;48(6):746-748. doi: 10.1016/j.devcel.2019.03.004.

PMID:
30913405
3.

Microtubule Dynamics, Kinesin-1 Sliding, and Dynein Action Drive Growth of Cell Processes.

Oelz DB, Del Castillo U, Gelfand VI, Mogilner A.

Biophys J. 2018 Oct 16;115(8):1614-1624. doi: 10.1016/j.bpj.2018.08.046. Epub 2018 Sep 11.

PMID:
30268540
4.

Ooplasmic flow cooperates with transport and anchorage in Drosophila oocyte posterior determination.

Lu W, Lakonishok M, Serpinskaya AS, Kirchenbüechler D, Ling SC, Gelfand VI.

J Cell Biol. 2018 Oct 1;217(10):3497-3511. doi: 10.1083/jcb.201709174. Epub 2018 Jul 23.

5.

Kinesin-dependent transport of keratin filaments: a unified mechanism for intermediate filament transport.

Robert A, Tian P, Adam SA, Kittisopikul M, Jaqaman K, Goldman RD, Gelfand VI.

FASEB J. 2019 Jan;33(1):388-399. doi: 10.1096/fj.201800604R. Epub 2018 Jun 26.

PMID:
29944446
6.

Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action.

Steinman JB, Santarossa CC, Miller RM, Yu LS, Serpinskaya AS, Furukawa H, Morimoto S, Tanaka Y, Nishitani M, Asano M, Zalyte R, Ondrus AE, Johnson AG, Ye F, Nachury MV, Fukase Y, Aso K, Foley MA, Gelfand VI, Chen JK, Carter AP, Kapoor TM.

Elife. 2017 May 19;6. pii: e25174. doi: 10.7554/eLife.25174.

7.

Microtubule-Based Transport and the Distribution, Tethering, and Organization of Organelles.

Barlan K, Gelfand VI.

Cold Spring Harb Perspect Biol. 2017 May 1;9(5). pii: a025817. doi: 10.1101/cshperspect.a025817. Review.

8.

Moonlighting Motors: Kinesin, Dynein, and Cell Polarity.

Lu W, Gelfand VI.

Trends Cell Biol. 2017 Jul;27(7):505-514. doi: 10.1016/j.tcb.2017.02.005. Epub 2017 Mar 8. Review.

9.

Role of kinesin-1-based microtubule sliding in Drosophila nervous system development.

Winding M, Kelliher MT, Lu W, Wildonger J, Gelfand VI.

Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):E4985-94. doi: 10.1073/pnas.1522416113. Epub 2016 Aug 10.

10.

Microtubule-microtubule sliding by kinesin-1 is essential for normal cytoplasmic streaming in Drosophila oocytes.

Lu W, Winding M, Lakonishok M, Wildonger J, Gelfand VI.

Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):E4995-5004. doi: 10.1073/pnas.1522424113. Epub 2016 Aug 10.

11.

Engineered kinesin motor proteins amenable to small-molecule inhibition.

Engelke MF, Winding M, Yue Y, Shastry S, Teloni F, Reddy S, Blasius TL, Soppina P, Hancock WO, Gelfand VI, Verhey KJ.

Nat Commun. 2016 Apr 5;7:11159. doi: 10.1038/ncomms11159.

12.

Methods for Determining the Cellular Functions of Vimentin Intermediate Filaments.

Ridge KM, Shumaker D, Robert A, Hookway C, Gelfand VI, Janmey PA, Lowery J, Guo M, Weitz DA, Kuczmarski E, Goldman RD.

Methods Enzymol. 2016;568:389-426. doi: 10.1016/bs.mie.2015.09.036. Epub 2015 Dec 19.

13.

A Genome-wide RNAi Screen for Microtubule Bundle Formation and Lysosome Motility Regulation in Drosophila S2 Cells.

Jolly AL, Luan CH, Dusel BE, Dunne SF, Winding M, Dixit VJ, Robins C, Saluk JL, Logan DJ, Carpenter AE, Sharma M, Dean D, Cohen AR, Gelfand VI.

Cell Rep. 2016 Jan 26;14(3):611-620. doi: 10.1016/j.celrep.2015.12.051. Epub 2016 Jan 7.

14.

Intermediate filament dynamics: What we can see now and why it matters.

Robert A, Hookway C, Gelfand VI.

Bioessays. 2016 Mar;38(3):232-43. doi: 10.1002/bies.201500142. Epub 2016 Jan 13. Review.

15.

Abnormal intermediate filament organization alters mitochondrial motility in giant axonal neuropathy fibroblasts.

Lowery J, Jain N, Kuczmarski ER, Mahammad S, Goldman A, Gelfand VI, Opal P, Goldman RD.

Mol Biol Cell. 2016 Feb 15;27(4):608-16. doi: 10.1091/mbc.E15-09-0627. Epub 2015 Dec 23.

16.

Interplay between kinesin-1 and cortical dynein during axonal outgrowth and microtubule organization in Drosophila neurons.

del Castillo U, Winding M, Lu W, Gelfand VI.

Elife. 2015 Dec 28;4:e10140. doi: 10.7554/eLife.10140.

17.

Vimentin filament precursors exchange subunits in an ATP-dependent manner.

Robert A, Rossow MJ, Hookway C, Adam SA, Gelfand VI.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):E3505-14. doi: 10.1073/pnas.1505303112. Epub 2015 Jun 24.

18.

Microtubule-dependent transport and dynamics of vimentin intermediate filaments.

Hookway C, Ding L, Davidson MW, Rappoport JZ, Danuser G, Gelfand VI.

Mol Biol Cell. 2015 May 1;26(9):1675-86. doi: 10.1091/mbc.E14-09-1398. Epub 2015 Feb 25.

19.

Kinesin-1-powered microtubule sliding initiates axonal regeneration in Drosophila cultured neurons.

Lu W, Lakonishok M, Gelfand VI.

Mol Biol Cell. 2015 Apr 1;26(7):1296-307. doi: 10.1091/mbc.E14-10-1423. Epub 2015 Feb 5.

20.

Pavarotti/MKLP1 regulates microtubule sliding and neurite outgrowth in Drosophila neurons.

Del Castillo U, Lu W, Winding M, Lakonishok M, Gelfand VI.

Curr Biol. 2015 Jan 19;25(2):200-205. doi: 10.1016/j.cub.2014.11.008. Epub 2014 Dec 31.

21.

Mitochondrial membrane potential is regulated by vimentin intermediate filaments.

Chernoivanenko IS, Matveeva EA, Gelfand VI, Goldman RD, Minin AA.

FASEB J. 2015 Mar;29(3):820-7. doi: 10.1096/fj.14-259903. Epub 2014 Nov 17.

22.

Drosophila Strip serves as a platform for early endosome organization during axon elongation.

Sakuma C, Kawauchi T, Haraguchi S, Shikanai M, Yamaguchi Y, Gelfand VI, Luo L, Miura M, Chihara T.

Nat Commun. 2014 Oct 14;5:5180. doi: 10.1038/ncomms6180.

23.

Microtubule-dependent transport of vimentin filament precursors is regulated by actin and by the concerted action of Rho- and p21-activated kinases.

Robert A, Herrmann H, Davidson MW, Gelfand VI.

FASEB J. 2014 Jul;28(7):2879-90. doi: 10.1096/fj.14-250019. Epub 2014 Mar 20.

24.

Breaking up isn't easy: myosin V and its cargoes need Dma1 ubiquitin ligase's help.

Winding M, Gelfand VI.

Dev Cell. 2014 Mar 10;28(5):479-80. doi: 10.1016/j.devcel.2014.02.016.

25.

Organelle transport in cultured Drosophila cells: S2 cell line and primary neurons.

Lu W, Del Castillo U, Gelfand VI.

J Vis Exp. 2013 Nov 20;(81):e50838. doi: 10.3791/50838.

26.

Protein kinase Darkener of apricot and its substrate EF1γ regulate organelle transport along microtubules.

Serpinskaya AS, Tuphile K, Rabinow L, Gelfand VI.

J Cell Sci. 2014 Jan 1;127(Pt 1):33-9. doi: 10.1242/jcs.123885. Epub 2013 Oct 25.

27.

Initial neurite outgrowth in Drosophila neurons is driven by kinesin-powered microtubule sliding.

Lu W, Fox P, Lakonishok M, Davidson MW, Gelfand VI.

Curr Biol. 2013 Jun 3;23(11):1018-23. doi: 10.1016/j.cub.2013.04.050. Epub 2013 May 23.

28.

The journey of the organelle: teamwork and regulation in intracellular transport.

Barlan K, Rossow MJ, Gelfand VI.

Curr Opin Cell Biol. 2013 Aug;25(4):483-8. doi: 10.1016/j.ceb.2013.02.018. Epub 2013 Mar 17. Review.

29.

Molecular motors.

Trybus KM, Gelfand VI.

Mol Biol Cell. 2013 Mar;24(6):672. doi: 10.1091/mbc.E12-12-0873. No abstract available.

30.

The microtubule-binding protein ensconsin is an essential cofactor of kinesin-1.

Barlan K, Lu W, Gelfand VI.

Curr Biol. 2013 Feb 18;23(4):317-22. doi: 10.1016/j.cub.2013.01.008. Epub 2013 Feb 7.

31.

Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein.

Firestone AJ, Weinger JS, Maldonado M, Barlan K, Langston LD, O'Donnell M, Gelfand VI, Kapoor TM, Chen JK.

Nature. 2012 Mar 18;484(7392):125-9. doi: 10.1038/nature10936.

32.

Bidirectional intracellular transport: utility and mechanism.

Jolly AL, Gelfand VI.

Biochem Soc Trans. 2011 Oct;39(5):1126-30. doi: 10.1042/BST0391126.

33.

Vimentin intermediate filaments modulate the motility of mitochondria.

Nekrasova OE, Mendez MG, Chernoivanenko IS, Tyurin-Kuzmin PA, Kuczmarski ER, Gelfand VI, Goldman RD, Minin AA.

Mol Biol Cell. 2011 Jul 1;22(13):2282-9. doi: 10.1091/mbc.E10-09-0766. Epub 2011 May 11.

34.

Cytoplasmic microtubule sliding: An unconventional function of conventional kinesin.

Jolly AL, Gelfand VI.

Commun Integr Biol. 2010 Nov;3(6):589-91. doi: 10.4161/cib.3.6.13212. Epub 2010 Nov 1.

35.

Statistics of active transport in Xenopus melanophores cells.

Snezhko A, Barlan K, Aranson IS, Gelfand VI.

Biophys J. 2010 Nov 17;99(10):3216-23. doi: 10.1016/j.bpj.2010.09.065.

36.

Intracellular transport: ER and mitochondria meet and greet along designated tracks.

Barlan K, Gelfand VI.

Curr Biol. 2010 Oct 12;20(19):R845-7. doi: 10.1016/j.cub.2010.08.058.

37.

Kinesin-1 heavy chain mediates microtubule sliding to drive changes in cell shape.

Jolly AL, Kim H, Srinivasan D, Lakonishok M, Larson AG, Gelfand VI.

Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12151-6. doi: 10.1073/pnas.1004736107. Epub 2010 Jun 21.

38.

Microtubule-mediated transport of the tumor-suppressor protein Merlin and its mutants.

Benseñor LB, Barlan K, Rice SE, Fehon RG, Gelfand VI.

Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7311-6. doi: 10.1073/pnas.0907389107. Epub 2010 Apr 5.

39.

Opposite-polarity motors activate one another to trigger cargo transport in live cells.

Ally S, Larson AG, Barlan K, Rice SE, Gelfand VI.

J Cell Biol. 2009 Dec 28;187(7):1071-82. doi: 10.1083/jcb.200908075.

40.

Myosin-Va restrains the trafficking of Na+/K+-ATPase-containing vesicles in alveolar epithelial cells.

Lecuona E, Minin A, Trejo HE, Chen J, Comellas AP, Sun H, Grillo D, Nekrasova OE, Welch LC, Szleifer I, Gelfand VI, Sznajder JI.

J Cell Sci. 2009 Nov 1;122(Pt 21):3915-22. doi: 10.1242/jcs.046953. Epub 2009 Oct 6.

41.

Role of kinesin light chain-2 of kinesin-1 in the traffic of Na,K-ATPase-containing vesicles in alveolar epithelial cells.

Trejo HE, Lecuona E, Grillo D, Szleifer I, Nekrasova OE, Gelfand VI, Sznajder JI.

FASEB J. 2010 Feb;24(2):374-82. doi: 10.1096/fj.09-137802. Epub 2009 Sep 22.

42.

The dynamic properties of intermediate filaments during organelle transport.

Chang L, Barlan K, Chou YH, Grin B, Lakonishok M, Serpinskaya AS, Shumaker DK, Herrmann H, Gelfand VI, Goldman RD.

J Cell Sci. 2009 Aug 15;122(Pt 16):2914-23. doi: 10.1242/jcs.046789. Epub 2009 Jul 28.

43.

Alpha-E-catenin binds to dynamitin and regulates dynactin-mediated intracellular traffic.

Lien WH, Gelfand VI, Vasioukhin V.

J Cell Biol. 2008 Dec 15;183(6):989-97. doi: 10.1083/jcb.200805041.

44.

The role of microtubule movement in bidirectional organelle transport.

Kulic IM, Brown AE, Kim H, Kural C, Blehm B, Selvin PR, Nelson PC, Gelfand VI.

Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10011-6. doi: 10.1073/pnas.0800031105. Epub 2008 Jul 14.

45.

Motor-cargo release: CaMKII as a traffic cop.

Ally S, Jolly AL, Gelfand VI.

Nat Cell Biol. 2008 Jan;10(1):3-5. doi: 10.1038/ncb0108-3. No abstract available.

PMID:
18172423
46.

Rab32 regulates melanosome transport in Xenopus melanophores by protein kinase a recruitment.

Park M, Serpinskaya AS, Papalopulu N, Gelfand VI.

Curr Biol. 2007 Dec 4;17(23):2030-4. Epub 2007 Nov 8.

47.

Tracking melanosomes inside a cell to study molecular motors and their interaction.

Kural C, Serpinskaya AS, Chou YH, Goldman RD, Gelfand VI, Selvin PR.

Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5378-82. Epub 2007 Mar 16.

48.

Microtubule binding by dynactin is required for microtubule organization but not cargo transport.

Kim H, Ling SC, Rogers GC, Kural C, Selvin PR, Rogers SL, Gelfand VI.

J Cell Biol. 2007 Feb 26;176(5):641-51.

49.

Paradigm lost: milton connects kinesin heavy chain to miro on mitochondria.

Rice SE, Gelfand VI.

J Cell Biol. 2006 May 22;173(4):459-61. Review.

50.

Regulation of mitochondria distribution by RhoA and formins.

Minin AA, Kulik AV, Gyoeva FK, Li Y, Goshima G, Gelfand VI.

J Cell Sci. 2006 Feb 15;119(Pt 4):659-70. Epub 2006 Jan 24.

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