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Items: 1 to 50 of 53

1.

Deficits in developmental neurogenesis and dendritic spine maturation in mice lacking the serine protease inhibitor neuroserpin.

Hermann M, Reumann R, Schostak K, Kement D, Gelderblom M, Bernreuther C, Frischknecht R, Schipanski A, Marik S, Krasemann S, Sepulveda-Falla D, Schweizer M, Magnus T, Glatzel M, Galliciotti G.

Mol Cell Neurosci. 2020 Jan;102:103420. doi: 10.1016/j.mcn.2019.103420. Epub 2019 Dec 2.

2.

Intravenous Immunoglobulin (IVIg) Induce a Protective Phenotype in Microglia Preventing Neuronal Cell Death in Ischaemic Stroke.

Häußler V, Daehn T, Rissiek B, Roth V, Gerloff C, Arumugam TV, Magnus T, Gelderblom M.

Neuromolecular Med. 2020 Mar;22(1):121-132. doi: 10.1007/s12017-019-08571-5. Epub 2019 Sep 26.

PMID:
31559534
3.

Fatal PCR-negative herpes simplex virus-1 encephalitis with GABAA receptor antibodies.

Schuster S, Abrante L, Matschke J, Lütgehetmann M, Holst B, Gelderblom M, Braass H, Leypoldt F, Magnus T.

Neurol Neuroimmunol Neuroinflamm. 2019 Sep 25;6(6). pii: e624. doi: 10.1212/NXI.0000000000000624. Print 2019 Nov. No abstract available.

4.

Peripheral nervous system alterations in infant and adult neurofibromatosis type 2.

Godel T, Bäumer P, Farschtschi S, Gugel I, Kronlage M, Hofstadler B, Heiland S, Gelderblom M, Bendszus M, Mautner VF.

Neurology. 2019 Aug 6;93(6):e590-e598. doi: 10.1212/WNL.0000000000007898. Epub 2019 Jul 12.

PMID:
31300546
5.

[Contrast-induced neurotoxicity mimicking an acute brainstem infarction].

Deb-Chatterji M, Schäfer L, Grzyska U, Gelderblom M.

Nervenarzt. 2020 Feb;91(2):148-149. doi: 10.1007/s00115-019-0727-1. German. No abstract available.

PMID:
31073669
6.

Stroke-mimics: An acute brainstem syndrome after intravenous contrast medium application as a rare cause of contrast-induced neurotoxicity.

Deb-Chatterji M, Schäfer L, Grzyska U, Gelderblom M.

Clin Neurol Neurosurg. 2018 Nov;174:244-246. doi: 10.1016/j.clineuro.2018.10.002. Epub 2018 Oct 3. No abstract available.

PMID:
30308472
7.

IL-33 modulates inflammatory brain injury but exacerbates systemic immunosuppression following ischemic stroke.

Zhang SR, Piepke M, Chu HX, Broughton BR, Shim R, Wong CH, Lee S, Evans MA, Vinh A, Sakkal S, Arumugam TV, Magnus T, Huber S, Gelderblom M, Drummond GR, Sobey CG, Kim HA.

JCI Insight. 2018 Sep 20;3(18). pii: 121560. doi: 10.1172/jci.insight.121560. eCollection 2018 Sep 20.

8.

Evidence that NLRC4 inflammasome mediates apoptotic and pyroptotic microglial death following ischemic stroke.

Poh L, Kang SW, Baik SH, Ng GYQ, She DT, Balaganapathy P, Dheen ST, Magnus T, Gelderblom M, Sobey CG, Koo EH, Fann DY, Arumugam TV.

Brain Behav Immun. 2019 Jan;75:34-47. doi: 10.1016/j.bbi.2018.09.001. Epub 2018 Sep 5.

PMID:
30195027
9.

Danger signals in stroke and their role on microglia activation after ischemia.

Gülke E, Gelderblom M, Magnus T.

Ther Adv Neurol Disord. 2018 May 22;11:1756286418774254. doi: 10.1177/1756286418774254. eCollection 2018. Review.

10.

Nerve trauma of the lower extremity: evaluation of 60,422 leg injured patients from the TraumaRegister DGU® between 2002 and 2015.

Huckhagel T, Nüchtern J, Regelsberger J, Gelderblom M, Lefering R; TraumaRegister DGU®.

Scand J Trauma Resusc Emerg Med. 2018 May 15;26(1):40. doi: 10.1186/s13049-018-0502-5.

11.

Transcriptome analysis reveals intermittent fasting-induced genetic changes in ischemic stroke.

Kim J, Kang SW, Mallilankaraman K, Baik SH, Lim JC, Balaganapathy P, She DT, Lok KZ, Fann DY, Thambiayah U, Tang SC, Stranahan AM, Dheen ST, Gelderblom M, Seet RC, Karamyan VT, Vemuganti R, Sobey CG, Mattson MP, Jo DG, Arumugam TV.

Hum Mol Genet. 2018 Jul 1;27(13):2405. doi: 10.1093/hmg/ddy138. No abstract available.

12.

Transcriptome analysis reveals intermittent fasting-induced genetic changes in ischemic stroke.

Kim J, Kang SW, Mallilankaraman K, Baik SH, Lim JC, Balaganapathy P, She DT, Lok KZ, Fann DY, Thambiayah U, Tang SC, Stranahan AM, Dheen ST, Gelderblom M, Seet RC, Karamyan VT, Vemuganti R, Sobey CG, Mattson MP, Jo DG, Arumugam TV.

Hum Mol Genet. 2018 May 1;27(9):1497-1513. doi: 10.1093/hmg/ddy057. Erratum in: Hum Mol Genet. 2018 Jul 1;27(13):2405.

13.

IL-23 (Interleukin-23)-Producing Conventional Dendritic Cells Control the Detrimental IL-17 (Interleukin-17) Response in Stroke.

Gelderblom M, Gallizioli M, Ludewig P, Thom V, Arunachalam P, Rissiek B, Bernreuther C, Glatzel M, Korn T, Arumugam TV, Sedlacik J, Gerloff C, Tolosa E, Planas AM, Magnus T.

Stroke. 2018 Jan;49(1):155-164. doi: 10.1161/STROKEAHA.117.019101. Epub 2017 Dec 6.

PMID:
29212740
14.

Ecto-ADP-ribosyltransferase ARTC2.1 functionally modulates FcγR1 and FcγR2B on murine microglia.

Rissiek B, Menzel S, Leutert M, Cordes M, Behr S, Jank L, Ludewig P, Gelderblom M, Rissiek A, Adriouch S, Haag F, Hottiger MO, Koch-Nolte F, Magnus T.

Sci Rep. 2017 Nov 28;7(1):16477. doi: 10.1038/s41598-017-16613-w.

15.

Somatosensory evoked potentials in patients with high-grade aneurysmal subarachnoid hemorrhage.

Mende KC, Gelderblom M, Schwarz C, Czorlich P, Schmidt NO, Vettorazzi E, Regelsberger J, Westphal M, Abboud T.

Neurosurg Focus. 2017 Nov;43(5):E17. doi: 10.3171/2017.7.FOCUS17427.

PMID:
29088953
16.

Therapeutic Potential of Intravenous Immunoglobulin in Acute Brain Injury.

Thom V, Arumugam TV, Magnus T, Gelderblom M.

Front Immunol. 2017 Jul 31;8:875. doi: 10.3389/fimmu.2017.00875. eCollection 2017. Review.

17.

CCR6 (CC Chemokine Receptor 6) Is Essential for the Migration of Detrimental Natural Interleukin-17-Producing γδ T Cells in Stroke.

Arunachalam P, Ludewig P, Melich P, Arumugam TV, Gerloff C, Prinz I, Magnus T, Gelderblom M.

Stroke. 2017 Jul;48(7):1957-1965. doi: 10.1161/STROKEAHA.117.016753. Epub 2017 Jun 13.

PMID:
28611085
18.

Recent progress in translational research on neurovascular and neurodegenerative disorders.

Demuth HU, Dijkhuizen RM, Farr TD, Gelderblom M, Horsburgh K, Iadecola C, Mcleod DD, Michalski D, Murphy TH, Orbe J, Otte WM, Petzold GC, Plesnila N, Reiser G, Reymann KG, Rueger MA, Saur D, Savitz SI, Schilling S, Spratt NJ, Turner RJ, Vemuganti R, Vivien D, Yepes M, Zille M, Boltze J; ISN&N meeting contributors.

Restor Neurol Neurosci. 2017;35(1):87-103. doi: 10.3233/RNN-160690. Review.

19.

An atypical role for the myeloid receptor Mincle in central nervous system injury.

Arumugam TV, Manzanero S, Furtado M, Biggins PJ, Hsieh YH, Gelderblom M, MacDonald KP, Salimova E, Li YI, Korn O, Dewar D, Macrae IM, Ashman RB, Tang SC, Rosenthal NA, Ruitenberg MJ, Magnus T, Wells CA.

J Cereb Blood Flow Metab. 2017 Jun;37(6):2098-2111. doi: 10.1177/0271678X16661201. Epub 2016 Jan 1.

20.

[Neuralgic amyotrophy: an extrahepatic manifestation of hepatitis E].

Pischke S, Ryll U, De Weerth A, Ufer F, Gelderblom M.

Dtsch Med Wochenschr. 2016 Aug;141(17):1239-42. doi: 10.1055/s-0042-102289. Epub 2016 Aug 24. German.

PMID:
27557071
21.

Muscle action potential scans and ultrasound imaging in neurofibromatosis type 2.

Farschtschi S, Gelderblom M, Buschbaum S, Bostock H, Grafe P, Mautner VF.

Muscle Nerve. 2017 Mar;55(3):350-358. doi: 10.1002/mus.25256. Epub 2016 Dec 16.

PMID:
27422240
22.

IL-17 production by CSF lymphocytes as a biomarker for cerebral vasculitis.

Thom V, Schmid S, Gelderblom M, Hackbusch R, Kolster M, Schuster S, Thomalla G, Keminer O, Pleß O, Bernreuther C, Glatzel M, Wegscheider K, Gerloff C, Magnus T, Tolosa E.

Neurol Neuroimmunol Neuroinflamm. 2016 Mar 21;3(2):e214. doi: 10.1212/NXI.0000000000000214. eCollection 2016 Apr.

23.

Dendritic cells in brain diseases.

Ludewig P, Gallizioli M, Urra X, Behr S, Brait VH, Gelderblom M, Magnus T, Planas AM.

Biochim Biophys Acta. 2016 Mar;1862(3):352-67. doi: 10.1016/j.bbadis.2015.11.003. Epub 2015 Nov 10. Review. No abstract available.

24.

Danger signals in stroke.

Gelderblom M, Sobey CG, Kleinschnitz C, Magnus T.

Ageing Res Rev. 2015 Nov;24(Pt A):77-82. doi: 10.1016/j.arr.2015.07.004. Epub 2015 Jul 22. Review.

PMID:
26210897
25.

γδ T cells as early sensors of tissue damage and mediators of secondary neurodegeneration.

Gelderblom M, Arunachalam P, Magnus T.

Front Cell Neurosci. 2014 Nov 5;8:368. doi: 10.3389/fncel.2014.00368. eCollection 2014. Review.

26.

Transient receptor potential melastatin subfamily member 2 cation channel regulates detrimental immune cell invasion in ischemic stroke.

Gelderblom M, Melzer N, Schattling B, Göb E, Hicking G, Arunachalam P, Bittner S, Ufer F, Herrmann AM, Bernreuther C, Glatzel M, Gerloff C, Kleinschnitz C, Meuth SG, Friese MA, Magnus T.

Stroke. 2014 Nov;45(11):3395-402. doi: 10.1161/STROKEAHA.114.005836. Epub 2014 Sep 18.

PMID:
25236871
27.

Role of CCR2 in inflammatory conditions of the central nervous system.

Chu HX, Arumugam TV, Gelderblom M, Magnus T, Drummond GR, Sobey CG.

J Cereb Blood Flow Metab. 2014 Sep;34(9):1425-9. doi: 10.1038/jcbfm.2014.120. Epub 2014 Jul 2. Review.

28.

Blocking of α4 integrin does not protect from acute ischemic stroke in mice.

Langhauser F, Kraft P, Göb E, Leinweber J, Schuhmann MK, Lorenz K, Gelderblom M, Bittner S, Meuth SG, Wiendl H, Magnus T, Kleinschnitz C.

Stroke. 2014 Jun;45(6):1799-806. doi: 10.1161/STROKEAHA.114.005000. Epub 2014 Apr 17.

PMID:
24743435
29.

PI3Kδ inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model.

Low PC, Manzanero S, Mohannak N, Narayana VK, Nguyen TH, Kvaskoff D, Brennan FH, Ruitenberg MJ, Gelderblom M, Magnus T, Kim HA, Broughton BR, Sobey CG, Vanhaesebroeck B, Stow JL, Arumugam TV, Meunier FA.

Nat Commun. 2014 Mar 14;5:3450. doi: 10.1038/ncomms4450.

PMID:
24625684
30.

Immune cell infiltration in malignant middle cerebral artery infarction: comparison with transient cerebral ischemia.

Chu HX, Kim HA, Lee S, Moore JP, Chan CT, Vinh A, Gelderblom M, Arumugam TV, Broughton BR, Drummond GR, Sobey CG.

J Cereb Blood Flow Metab. 2014 Mar;34(3):450-9. doi: 10.1038/jcbfm.2013.217. Epub 2013 Dec 11.

31.

Evidence that collaboration between HIF-1α and Notch-1 promotes neuronal cell death in ischemic stroke.

Cheng YL, Park JS, Manzanero S, Choi Y, Baik SH, Okun E, Gelderblom M, Fann DY, Magnus T, Launikonis BS, Mattson MP, Sobey CG, Jo DG, Arumugam TV.

Neurobiol Dis. 2014 Feb;62:286-95. doi: 10.1016/j.nbd.2013.10.009. Epub 2013 Oct 16.

32.

Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke.

Fann DY, Lee SY, Manzanero S, Tang SC, Gelderblom M, Chunduri P, Bernreuther C, Glatzel M, Cheng YL, Thundyil J, Widiapradja A, Lok KZ, Foo SL, Wang YC, Li YI, Drummond GR, Basta M, Magnus T, Jo DG, Mattson MP, Sobey CG, Arumugam TV.

Cell Death Dis. 2013 Sep 5;4:e790. doi: 10.1038/cddis.2013.326.

33.

Plasma levels of neuron specific enolase quantify the extent of neuronal injury in murine models of ischemic stroke and multiple sclerosis.

Gelderblom M, Daehn T, Schattling B, Ludewig P, Bernreuther C, Arunachalam P, Matschke J, Glatzel M, Gerloff C, Friese MA, Magnus T.

Neurobiol Dis. 2013 Nov;59:177-82. doi: 10.1016/j.nbd.2013.07.017. Epub 2013 Aug 9.

PMID:
23932916
34.

Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits MMP-9-mediated blood-brain-barrier breakdown in a mouse model for ischemic stroke.

Ludewig P, Sedlacik J, Gelderblom M, Bernreuther C, Korkusuz Y, Wagener C, Gerloff C, Fiehler J, Magnus T, Horst AK.

Circ Res. 2013 Sep 27;113(8):1013-22. doi: 10.1161/CIRCRESAHA.113.301207. Epub 2013 Jun 18.

PMID:
23780386
35.

Deficiency in serine protease inhibitor neuroserpin exacerbates ischemic brain injury by increased postischemic inflammation.

Gelderblom M, Neumann M, Ludewig P, Bernreuther C, Krasemann S, Arunachalam P, Gerloff C, Glatzel M, Magnus T.

PLoS One. 2013 May 3;8(5):e63118. doi: 10.1371/journal.pone.0063118. Print 2013.

36.

Recovery from severe frontotemporal dysfunction at 3years after N-methyl-d-aspartic acid (NMDA) receptor antibody encephalitis.

Leypoldt F, Gelderblom M, Schöttle D, Hoffmann S, Wandinger KP.

J Clin Neurosci. 2013 Apr;20(4):611-3. doi: 10.1016/j.jocn.2012.03.036. Epub 2013 Jan 11.

PMID:
23313527
37.

Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.

Gelderblom M, Weymar A, Bernreuther C, Velden J, Arunachalam P, Steinbach K, Orthey E, Arumugam TV, Leypoldt F, Simova O, Thom V, Friese MA, Prinz I, Hölscher C, Glatzel M, Korn T, Gerloff C, Tolosa E, Magnus T.

Blood. 2012 Nov 1;120(18):3793-802. doi: 10.1182/blood-2012-02-412726. Epub 2012 Sep 13.

PMID:
22976954
38.

Fluorodeoxyglucose positron emission tomography in anti-N-methyl-D-aspartate receptor encephalitis: distinct pattern of disease.

Leypoldt F, Buchert R, Kleiter I, Marienhagen J, Gelderblom M, Magnus T, Dalmau J, Gerloff C, Lewerenz J.

J Neurol Neurosurg Psychiatry. 2012 Jul;83(7):681-6. doi: 10.1136/jnnp-2011-301969. Epub 2012 May 7.

39.

Intravenous immunoglobulin protects neurons against amyloid beta-peptide toxicity and ischemic stroke by attenuating multiple cell death pathways.

Widiapradja A, Vegh V, Lok KZ, Manzanero S, Thundyil J, Gelderblom M, Cheng YL, Pavlovski D, Tang SC, Jo DG, Magnus T, Chan SL, Sobey CG, Reutens D, Basta M, Mattson MP, Arumugam TV.

J Neurochem. 2012 Jul;122(2):321-32. doi: 10.1111/j.1471-4159.2012.07754.x. Epub 2012 Apr 27.

40.

C5a receptor (CD88) inhibition improves hypothermia-induced neuroprotection in an in vitro ischemic model.

Thundyil J, Pavlovski D, Hsieh YH, Gelderblom M, Magnus T, Fairlie DP, Arumugam TV.

Neuromolecular Med. 2012 Mar;14(1):30-9. doi: 10.1007/s12017-012-8167-0. Epub 2012 Jan 17.

PMID:
22249919
41.

The flavonoid fisetin attenuates postischemic immune cell infiltration, activation and infarct size after transient cerebral middle artery occlusion in mice.

Gelderblom M, Leypoldt F, Lewerenz J, Birkenmayer G, Orozco D, Ludewig P, Thundyil J, Arumugam TV, Gerloff C, Tolosa E, Maher P, Magnus T.

J Cereb Blood Flow Metab. 2012 May;32(5):835-43. doi: 10.1038/jcbfm.2011.189. Epub 2012 Jan 11.

42.

Calorie restriction and stroke.

Manzanero S, Gelderblom M, Magnus T, Arumugam TV.

Exp Transl Stroke Med. 2011 Sep 12;3:8. doi: 10.1186/2040-7378-3-8.

43.

Intestinal ischemia-reperfusion injury leads to inflammatory changes in the brain.

Hsieh YH, McCartney K, Moore TA, Thundyil J, Gelderblom M, Manzanero S, Arumugam TV.

Shock. 2011 Oct;36(4):424-30. doi: 10.1097/SHK.0b013e3182295f91.

PMID:
21701413
44.

CD38 exacerbates focal cytokine production, postischemic inflammation and brain injury after focal cerebral ischemia.

Choe CU, Lardong K, Gelderblom M, Ludewig P, Leypoldt F, Koch-Nolte F, Gerloff C, Magnus T.

PLoS One. 2011;6(5):e19046. doi: 10.1371/journal.pone.0019046. Epub 2011 May 13. Erratum in: PLoS One. 2011;6(7). doi:10.1371/annotation/295c388d-013d-4bb9-b4e4-da8e88317594.

45.

Evidence that gamma-secretase-mediated Notch signaling induces neuronal cell death via the nuclear factor-kappaB-Bcl-2-interacting mediator of cell death pathway in ischemic stroke.

Arumugam TV, Cheng YL, Choi Y, Choi YH, Yang S, Yun YK, Park JS, Yang DK, Thundyil J, Gelderblom M, Karamyan VT, Tang SC, Chan SL, Magnus T, Sobey CG, Jo DG.

Mol Pharmacol. 2011 Jul;80(1):23-31. doi: 10.1124/mol.111.071076. Epub 2011 Mar 30. Erratum in: Mol Pharmacol. 2011 Sep;80(3):550.

PMID:
21450930
46.

Benefits and pitfalls of scientific research during undergraduate medical education.

Kuhnigk O, Böthern AM, Reimer J, Schäfer I, Biegler A, Jueptner M, Gelderblom M, Harendza S.

GMS Z Med Ausbild. 2010;27(5):Doc72. doi: 10.3205/zma000709. Epub 2010 Nov 15.

47.

Dimethylarginine dimethylaminohydrolase-1 transgenic mice are not protected from ischemic stroke.

Leypoldt F, Choe CU, Gelderblom M, von Leitner EC, Atzler D, Schwedhelm E, Gerloff C, Sydow K, Böger RH, Magnus T.

PLoS One. 2009 Oct 7;4(10):e7337. doi: 10.1371/journal.pone.0007337.

48.

Temporal and spatial dynamics of cerebral immune cell accumulation in stroke.

Gelderblom M, Leypoldt F, Steinbach K, Behrens D, Choe CU, Siler DA, Arumugam TV, Orthey E, Gerloff C, Tolosa E, Magnus T.

Stroke. 2009 May;40(5):1849-57. doi: 10.1161/STROKEAHA.108.534503. Epub 2009 Mar 5.

PMID:
19265055
49.

The neuropeptide head activator is a high-affinity ligand for the orphan G-protein-coupled receptor GPR37.

Rezgaoui M, Süsens U, Ignatov A, Gelderblom M, Glassmeier G, Franke I, Urny J, Imai Y, Takahashi R, Schaller HC.

J Cell Sci. 2006 Feb 1;119(Pt 3):542-9. Erratum in: J Cell Sci. 2006 Mar 1;119(5):970.

50.

c-Jun N-terminal kinases (JNKs) and the cytoskeleton--functions beyond neurodegeneration.

Gelderblom M, Eminel S, Herdegen T, Waetzig V.

Int J Dev Neurosci. 2004 Nov;22(7):559-64. Review.

PMID:
15465286

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