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Items: 17


Practical considerations for printing high-density glycan microarrays to study weak carbohydrate-protein interactions.

Ruprecht C, Geissner A, Seeberger PH, Pfrengle F.

Carbohydr Res. 2019 Jul 15;481:31-35. doi: 10.1016/j.carres.2019.06.006. Epub 2019 Jun 13.


Microbe-focused glycan array screening platform.

Geissner A, Reinhardt A, Rademacher C, Johannssen T, Monteiro J, Lepenies B, Thépaut M, Fieschi F, Mrázková J, Wimmerova M, Schuhmacher F, Götze S, Grünstein D, Guo X, Hahm HS, Kandasamy J, Leonori D, Martin CE, Parameswarappa SG, Pasari S, Schlegel MK, Tanaka H, Xiao G, Yang Y, Pereira CL, Anish C, Seeberger PH.

Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):1958-1967. doi: 10.1073/pnas.1800853116. Epub 2019 Jan 22.


A modular synthetic route to size-defined immunogenic Haemophilus influenzae b antigens is key to the identification of an octasaccharide lead vaccine candidate.

Baek JY, Geissner A, Rathwell DCK, Meierhofer D, Pereira CL, Seeberger PH.

Chem Sci. 2017 Dec 11;9(5):1279-1288. doi: 10.1039/c7sc04521b. eCollection 2018 Feb 7.


Semisynthetic glycoconjugate vaccine candidate against Streptococcus pneumoniae serotype 5.

Lisboa MP, Khan N, Martin C, Xu FF, Reppe K, Geissner A, Govindan S, Witzenrath M, Pereira CL, Seeberger PH.

Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11063-11068. doi: 10.1073/pnas.1706875114. Epub 2017 Oct 2.


Automated glycan assembly of branched β-(1,3)-glucans to identify antibody epitopes.

Weishaupt MW, Hahm HS, Geissner A, Seeberger PH.

Chem Commun (Camb). 2017 Mar 23;53(25):3591-3594. doi: 10.1039/c7cc00520b.


Calcium-Independent Activation of an Allosteric Network in Langerin by Heparin Oligosaccharides.

Hanske J, Wawrzinek R, Geissner A, Wamhoff EC, Sellrie K, Schmidt H, Seeberger PH, Rademacher C.

Chembiochem. 2017 Jul 4;18(13):1183-1187. doi: 10.1002/cbic.201700027. Epub 2017 Mar 29.


A Semi-synthetic Oligosaccharide Conjugate Vaccine Candidate Confers Protection against Streptococcus pneumoniae Serotype 3 Infection.

Parameswarappa SG, Reppe K, Geissner A, Ménová P, Govindan S, Calow ADJ, Wahlbrink A, Weishaupt MW, Monnanda BP, Bell RL, Pirofski LA, Suttorp N, Sander LE, Witzenrath M, Pereira CL, Anish C, Seeberger PH.

Cell Chem Biol. 2016 Nov 17;23(11):1407-1416. doi: 10.1016/j.chembiol.2016.09.016. Epub 2016 Nov 3.


Structure binding relationship of human surfactant protein D and various lipopolysaccharide inner core structures.

Reinhardt A, Wehle M, Geissner A, Crouch EC, Kang Y, Yang Y, Anish C, Santer M, Seeberger PH.

J Struct Biol. 2016 Sep;195(3):387-395. doi: 10.1016/j.jsb.2016.06.019. Epub 2016 Jun 25.


Glycan Arrays: From Basic Biochemical Research to Bioanalytical and Biomedical Applications.

Geissner A, Seeberger PH.

Annu Rev Anal Chem (Palo Alto Calif). 2016 Jun 12;9(1):223-47. doi: 10.1146/annurev-anchem-071015-041641. Review.


Genetic characterization of an adapted pandemic 2009 H1N1 influenza virus that reveals improved replication rates in human lung epithelial cells.

Wörmann X, Lesch M, Welke RW, Okonechnikov K, Abdurishid M, Sieben C, Geissner A, Brinkmann V, Kastner M, Karner A, Zhu R, Hinterdorfer P, Anish C, Seeberger PH, Herrmann A, Meyer TF, Karlas A.

Virology. 2016 May;492:118-29. doi: 10.1016/j.virol.2016.02.002. Epub 2016 Feb 23.


Deciphering Antigenic Determinants of Streptococcus pneumoniae Serotype 4 Capsular Polysaccharide using Synthetic Oligosaccharides.

Geissner A, Pereira CL, Leddermann M, Anish C, Seeberger PH.

ACS Chem Biol. 2016 Feb 19;11(2):335-44. doi: 10.1021/acschembio.5b00768. Epub 2016 Jan 4.


Chemical Synthesis Elucidates the Immunological Importance of a Pyruvate Modification in the Capsular Polysaccharide of Streptococcus pneumoniae Serotype 4.

Pereira CL, Geissner A, Anish C, Seeberger PH.

Angew Chem Int Ed Engl. 2015 Aug 17;54(34):10016-9. doi: 10.1002/anie.201504847. Epub 2015 Jul 24.


Investigation of the protective properties of glycosylphosphatidylinositol-based vaccine candidates in a Toxoplasma gondii mouse challenge model.

Götze S, Reinhardt A, Geissner A, Azzouz N, Tsai YH, Kurucz R, Varón Silva D, Seeberger PH.

Glycobiology. 2015 Sep;25(9):984-91. doi: 10.1093/glycob/cwv040. Epub 2015 Jun 4.


Automated synthesis of arabinoxylan-oligosaccharides enables characterization of antibodies that recognize plant cell wall glycans.

Schmidt D, Schuhmacher F, Geissner A, Seeberger PH, Pfrengle F.

Chemistry. 2015 Apr 7;21(15):5709-13. doi: 10.1002/chem.201500065. Epub 2015 Feb 26.


Glycan arrays as tools for infectious disease research.

Geissner A, Anish C, Seeberger PH.

Curr Opin Chem Biol. 2014 Feb;18:38-45. doi: 10.1016/j.cbpa.2013.11.013. Epub 2013 Dec 30. Review.


Horizontal gene transfer contributed to the evolution of extracellular surface structures: the freshwater polyp Hydra is covered by a complex fibrous cuticle containing glycosaminoglycans and proteins of the PPOD and SWT (sweet tooth) families.

Böttger A, Doxey AC, Hess MW, Pfaller K, Salvenmoser W, Deutzmann R, Geissner A, Pauly B, Altstätter J, Münder S, Heim A, Gabius HJ, McConkey BJ, David CN.

PLoS One. 2012;7(12):e52278. doi: 10.1371/journal.pone.0052278. Epub 2012 Dec 27.


The SNF2 family ATPase LSH promotes phosphorylation of H2AX and efficient repair of DNA double-strand breaks in mammalian cells.

Burrage J, Termanis A, Geissner A, Myant K, Gordon K, Stancheva I.

J Cell Sci. 2012 Nov 15;125(Pt 22):5524-34. doi: 10.1242/jcs.111252. Epub 2012 Sep 3.

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