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Neurons differentiate magnitude and location of mechanical stimuli.

Gaub BM, Kasuba KC, Mace E, Strittmatter T, Laskowski PR, Geissler SA, Hierlemann A, Fussenegger M, Roska B, Müller DJ.

Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):848-856. doi: 10.1073/pnas.1909933117. Epub 2019 Dec 27.


Diagnosis of Metal Hypersensitivity in Total Knee Arthroplasty: A Case Report.

Schoon J, Ort MJ, Huesker K, Geissler S, Rakow A.

Front Immunol. 2019 Nov 27;10:2758. doi: 10.3389/fimmu.2019.02758. eCollection 2019.


Preclinical Toxicity Evaluation of Clinical Grade Placenta-Derived Decidua Stromal Cells.

Sadeghi B, Moretti G, Arnberg F, Samén E, Kohein B, Catar R, Kamhieh-Milz J, Geissler S, Moll G, Holmin S, Ringdén O.

Front Immunol. 2019 Nov 19;10:2685. doi: 10.3389/fimmu.2019.02685. eCollection 2019.


Multi-Parameter Analysis of Biobanked Human Bone Marrow Stromal Cells Shows Little Influence for Donor Age and Mild Comorbidities on Phenotypic and Functional Properties.

Andrzejewska A, Catar R, Schoon J, Qazi TH, Sass FA, Jacobi D, Blankenstein A, Reinke S, Krüger D, Streitz M, Schlickeiser S, Richter S, Souidi N, Beez C, Kamhieh-Milz J, Krüger U, Zemojtel T, Jürchott K, Strunk D, Reinke P, Duda G, Moll G, Geissler S.

Front Immunol. 2019 Nov 8;10:2474. doi: 10.3389/fimmu.2019.02474. eCollection 2019.


Niche-mimicking interactions in peptide-functionalized 3D hydrogels amplify mesenchymal stromal cell paracrine effects.

Qazi TH, Mooney DJ, Duda GN, Geissler S.

Biomaterials. 2020 Feb;230:119639. doi: 10.1016/j.biomaterials.2019.119639. Epub 2019 Nov 20.


The Allergic Bone Marrow? The Immuno-Capacity of the Human Bone Marrow in Context of Metal-Associated Hypersensitivity Reactions.

Ort MJ, Geissler S, Rakow A, Schoon J.

Front Immunol. 2019 Sep 18;10:2232. doi: 10.3389/fimmu.2019.02232. eCollection 2019. Review.


Oxidized alginate beads for tunable release of osteogenically potent mesenchymal stromal cells.

Xiang G, Lippens E, Hafeez S, Duda GN, Geissler S, Qazi TH.

Mater Sci Eng C Mater Biol Appl. 2019 Nov;104:109911. doi: 10.1016/j.msec.2019.109911. Epub 2019 Jun 22.


Individual Effector/Regulator T Cell Ratios Impact Bone Regeneration.

Schlundt C, Reinke S, Geissler S, Bucher CH, Giannini C, Märdian S, Dahne M, Kleber C, Samans B, Baron U, Duda GN, Volk HD, Schmidt-Bleek K.

Front Immunol. 2019 Aug 16;10:1954. doi: 10.3389/fimmu.2019.01954. eCollection 2019.


Novel reverse thia-analogs of fosmidomycin: Synthesis and antiplasmodial activity.

Lienau C, Gräwert T, Alves Avelar LA, Illarionov B, Held J, Knaab TC, Lungerich B, van Geelen L, Meier D, Geissler S, Cynis H, Riederer U, Buchholz M, Kalscheuer R, Bacher A, Mordmüller B, Fischer M, Kurz T.

Eur J Med Chem. 2019 Nov 1;181:111555. doi: 10.1016/j.ejmech.2019.07.058. Epub 2019 Jul 22.


Cell therapy to improve regeneration of skeletal muscle injuries.

Qazi TH, Duda GN, Ort MJ, Perka C, Geissler S, Winkler T.

J Cachexia Sarcopenia Muscle. 2019 Jun;10(3):501-516. doi: 10.1002/jcsm.12416. Epub 2019 Mar 6. Review.


Intravascular Mesenchymal Stromal/Stem Cell Therapy Product Diversification: Time for New Clinical Guidelines.

Moll G, Ankrum JA, Kamhieh-Milz J, Bieback K, Ringdén O, Volk HD, Geissler S, Reinke P.

Trends Mol Med. 2019 Feb;25(2):149-163. doi: 10.1016/j.molmed.2018.12.006. Epub 2019 Jan 30. Review.


Stimulation and Artifact-Suppression Techniques for In Vitro High-Density Microelectrode Array Systems.

Shadmani A, Viswam V, Chen Y, Bounik R, Dragas J, Radivojevic M, Geissler S, Sitnikov S, Muller J, Hierlemann A.

IEEE Trans Biomed Eng. 2019 Sep;66(9):2481-2490. doi: 10.1109/TBME.2018.2890530. Epub 2019 Jan 1.


A biomaterial with a channel-like pore architecture induces endochondral healing of bone defects.

Petersen A, Princ A, Korus G, Ellinghaus A, Leemhuis H, Herrera A, Klaumünzer A, Schreivogel S, Woloszyk A, Schmidt-Bleek K, Geissler S, Heschel I, Duda GN.

Nat Commun. 2018 Oct 25;9(1):4430. doi: 10.1038/s41467-018-06504-7.


Dosage and composition of bioactive glasses differentially regulate angiogenic and osteogenic response of human MSCs.

Qazi TH, Berkmann JC, Schoon J, Geißler S, Duda GN, Boccaccini AR, Lippens E.

J Biomed Mater Res A. 2018 Nov;106(11):2827-2837. doi: 10.1002/jbm.a.36470. Epub 2018 Oct 3.


Immunomodulatory placental-expanded, mesenchymal stromal cells improve muscle function following hip arthroplasty.

Winkler T, Perka C, von Roth P, Agres AN, Plage H, Preininger B, Pumberger M, Geissler S, Hagai EL, Ofir R, Pinzur L, Eyal E, Stoltenburg-Didinger G, Meisel C, Consentius C, Streitz M, Reinke P, Duda GN, Volk HD.

J Cachexia Sarcopenia Muscle. 2018 Oct;9(5):880-897. doi: 10.1002/jcsm.12316. Epub 2018 Sep 19.


Unraveling local tissue changes within severely injured skeletal muscles in response to MSC-based intervention using MALDI Imaging mass spectrometry.

Klein O, Strohschein K, Nebrich G, Fuchs M, Thiele H, Giavalisco P, Duda GN, Winkler T, Kobarg JH, Trede D, Geissler S.

Sci Rep. 2018 Aug 23;8(1):12677. doi: 10.1038/s41598-018-30990-w.


Loss of murine Gfi1 causes neutropenia and induces osteoporosis depending on the pathogen load and systemic inflammation.

Geissler S, Textor M, Stumpp S, Seitz S, Lekaj A, Brunk S, Klaassen S, Schinke T, Klein C, Mundlos S, Kornak U, Kühnisch J.

PLoS One. 2018 Jun 7;13(6):e0198510. doi: 10.1371/journal.pone.0198510. eCollection 2018.


Structure-Guided Design, Synthesis, and Characterization of Next-Generation Meprin β Inhibitors.

Ramsbeck D, Hamann A, Richter G, Schlenzig D, Geissler S, Nykiel V, Cynis H, Schilling S, Buchholz M.

J Med Chem. 2018 May 24;61(10):4578-4592. doi: 10.1021/acs.jmedchem.8b00330. Epub 2018 May 7.


Immunology Guides Skeletal Muscle Regeneration.

Sass FA, Fuchs M, Pumberger M, Geissler S, Duda GN, Perka C, Schmidt-Bleek K.

Int J Mol Sci. 2018 Mar 13;19(3). pii: E835. doi: 10.3390/ijms19030835. Review.


Rapid detection of periprosthetic joint infection using a combination of 16s rDNA polymerase chain reaction and lateral flow immunoassay: A Pilot Study.

Janz V, Schoon J, Morgenstern C, Preininger B, Reinke S, Duda G, Breitbach A, Perka CF, Geissler S.

Bone Joint Res. 2018 Jan;7(1):12-19. doi: 10.1302/2046-3758.71.BJR-2017-0103.R2.


Biomimetic hydrogels direct spinal progenitor cell differentiation and promote functional recovery after spinal cord injury.

Geissler SA, Sabin AL, Besser RR, Gooden OM, Shirk BD, Nguyen QM, Khaing ZZ, Schmidt CE.

J Neural Eng. 2018 Apr;15(2):025004. doi: 10.1088/1741-2552/aaa55c.


Tumour necrosis factor-alpha in uraemic serum promotes osteoblastic transition and calcification of vascular smooth muscle cells via extracellular signal-regulated kinases and activator protein 1/c-FOS-mediated induction of interleukin 6 expression.

Zickler D, Luecht C, Willy K, Chen L, Witowski J, Girndt M, Fiedler R, Storr M, Kamhieh-Milz J, Schoon J, Geissler S, Ringdén O, Schindler R, Moll G, Dragun D, Catar R.

Nephrol Dial Transplant. 2018 Apr 1;33(4):574-585. doi: 10.1093/ndt/gfx316.


Multi-elemental nanoparticle exposure after tantalum component failure in hip arthroplasty: In-depth analysis of a single case.

Schoon J, Geißler S, Traeger J, Luch A, Tentschert J, Perino G, Schulze F, Duda GN, Perka C, Rakow A.

Nanomedicine. 2017 Nov;13(8):2415-2423. doi: 10.1016/j.nano.2017.08.004. Epub 2017 Aug 16.


Biomaterials that promote cell-cell interactions enhance the paracrine function of MSCs.

Qazi TH, Mooney DJ, Duda GN, Geissler S.

Biomaterials. 2017 Sep;140:103-114. doi: 10.1016/j.biomaterials.2017.06.019. Epub 2017 Jun 18.


A Multi-Functional Microelectrode Array Featuring 59760 Electrodes, 2048 Electrophysiology Channels, Stimulation, Impedance Measurement and Neurotransmitter Detection Channels.

Dragas J, Viswam V, Shadmani A, Chen Y, Bounik R, Stettler A, Radivojevic M, Geissler S, Obien M, Müller J, Hierlemann A.

IEEE J Solid-State Circuits. 2017 Jun;52(6):1576-1590. doi: 10.1109/JSSC.2017.2686580. Epub 2017 Apr 27.


Targeting the Central Nervous System (CNS): A Review of Rabies Virus-Targeting Strategies.

Oswald M, Geissler S, Goepferich A.

Mol Pharm. 2017 Jul 3;14(7):2177-2196. doi: 10.1021/acs.molpharmaceut.7b00158. Epub 2017 Jun 16. Review.


Conducting polymer-based multilayer films for instructive biomaterial coatings.

Hardy JG, Li H, Chow JK, Geissler SA, McElroy AB, Nguy L, Hernandez DS, Schmidt CE.

Future Sci OA. 2015 Nov 2;1(4):FSO79. doi: 10.4155/fso.15.79. eCollection 2015 Nov.


CD31+ Cells From Peripheral Blood Facilitate Bone Regeneration in Biologically Impaired Conditions Through Combined Effects on Immunomodulation and Angiogenesis.

Sass FA, Schmidt-Bleek K, Ellinghaus A, Filter S, Rose A, Preininger B, Reinke S, Geissler S, Volk HD, Duda GN, Dienelt A.

J Bone Miner Res. 2017 May;32(5):902-912. doi: 10.1002/jbmr.3062. Epub 2017 Mar 1.


Determination of the activity of maleimide-functionalized phospholipids during preparation of liposomes.

Oswald M, Geissler S, Goepferich A.

Int J Pharm. 2016 Nov 30;514(1):93-102. doi: 10.1016/j.ijpharm.2016.06.116.


Cryopreserved or Fresh Mesenchymal Stromal Cells: Only a Matter of Taste or Key to Unleash the Full Clinical Potential of MSC Therapy?

Moll G, Geißler S, Catar R, Ignatowicz L, Hoogduijn MJ, Strunk D, Bieback K, Ringdén O.

Adv Exp Med Biol. 2016;951:77-98. Review.


Influence of Donor Age and Stimulation Intensity on Osteogenic Differentiation of Rat Mesenchymal Stromal Cells in Response to Focused Low-Intensity Pulsed Ultrasound.

Puts R, Albers J, Kadow-Romacker A, Geissler S, Raum K.

Ultrasound Med Biol. 2016 Dec;42(12):2965-2974. doi: 10.1016/j.ultrasmedbio.2016.08.012. Epub 2016 Sep 24.


Deposition Kinetics of Bioinspired Phenolic Coatings on Titanium Surfaces.

Geißler S, Barrantes A, Tengvall P, Messersmith PB, Tiainen H.

Langmuir. 2016 Aug 16;32(32):8050-60. doi: 10.1021/acs.langmuir.6b01959. Epub 2016 Aug 4.


Synthetic niche to modulate regenerative potential of MSCs and enhance skeletal muscle regeneration.

Pumberger M, Qazi TH, Ehrentraut MC, Textor M, Kueper J, Stoltenburg-Didinger G, Winkler T, von Roth P, Reinke S, Borselli C, Perka C, Mooney DJ, Duda GN, Geißler S.

Biomaterials. 2016 Aug;99:95-108. doi: 10.1016/j.biomaterials.2016.05.009. Epub 2016 May 10.


Effect of cathodic polarization on coating doxycycline on titanium surfaces.

Geißler S, Tiainen H, Haugen HJ.

Mater Sci Eng C Mater Biol Appl. 2016 Jun;63:359-66. doi: 10.1016/j.msec.2016.03.012. Epub 2016 Mar 3.


Generation of an iPS cell line from bone marrow derived mesenchymal stromal cells from an elderly patient.

Megges M, Geissler S, Duda GN, Adjaye J.

Stem Cell Res. 2015 Nov;15(3):565-8. doi: 10.1016/j.scr.2015.10.003. Epub 2015 Oct 9.


Oral intake of 7-dehydrocholesterol increases vitamin D3 concentrations in the liver and kidney.

Kühn J, Hirche F, Geissler S, Stangl GI.

J Steroid Biochem Mol Biol. 2016 Nov;164:199-204. doi: 10.1016/j.jsbmb.2015.12.017. Epub 2015 Dec 17.


HPLC analysis as a tool for assessing targeted liposome composition.

Oswald M, Platscher M, Geissler S, Goepferich A.

Int J Pharm. 2016 Jan 30;497(1-2):293-300. doi: 10.1016/j.ijpharm.2015.11.014. Epub 2015 Nov 10.


Macromol. Rapid Commun. 21/2015.

Hardy JG, Villancio-Wolter MK, Sukhavasi RC, Mouser DJ, Aguilar D Jr, Geissler SA, Kaplan DL, Schmidt CE.

Macromol Rapid Commun. 2015 Nov;36(21):1936. doi: 10.1002/marc.201570086.


Increased vitamin D levels at birth and in early infancy increase offspring allergy risk-evidence for involvement of epigenetic mechanisms.

Junge KM, Bauer T, Geissler S, Hirche F, Thürmann L, Bauer M, Trump S, Bieg M, Weichenhan D, Gu L, Mallm JP, Ishaque N, Mücke O, Röder S, Herberth G, Diez U, Borte M, Rippe K, Plass C, Hermann C, Stangl GI, Eils R, Lehmann I.

J Allergy Clin Immunol. 2016 Feb;137(2):610-3. doi: 10.1016/j.jaci.2015.06.040. Epub 2015 Aug 15. No abstract available.


Electrical Stimulation of Human Mesenchymal Stem Cells on Conductive Nanofibers Enhances their Differentiation toward Osteogenic Outcomes.

Hardy JG, Villancio-Wolter MK, Sukhavasi RC, Mouser DJ, Aguilar D Jr, Geissler SA, Kaplan DL, Schmidt CE.

Macromol Rapid Commun. 2015 Nov;36(21):1884-1890. doi: 10.1002/marc.201500233. Epub 2015 Jul 6.


Do Matrix Metalloproteases and Tissue Inhibitors of Metalloproteases in Tenocytes of the Rotator Cuff Differ with Varying Donor Characteristics?

Klatte-Schulz F, Aleyt T, Pauly S, Geißler S, Gerhardt C, Scheibel M, Wildemann B.

Int J Mol Sci. 2015 Jun 9;16(6):13141-57. doi: 10.3390/ijms160613141.


Instructive Conductive 3D Silk Foam-Based Bone Tissue Scaffolds Enable Electrical Stimulation of Stem Cells for Enhanced Osteogenic Differentiation.

Hardy JG, Geissler SA, Aguilar D Jr, Villancio-Wolter MK, Mouser DJ, Sukhavasi RC, Cornelison RC, Tien LW, Preda RC, Hayden RS, Chow JK, Nguy L, Kaplan DL, Schmidt CE.

Macromol Biosci. 2015 Nov;15(11):1490-6. doi: 10.1002/mabi.201500171. Epub 2015 Jun 1.


Biomaterials based strategies for skeletal muscle tissue engineering: existing technologies and future trends.

Qazi TH, Mooney DJ, Pumberger M, Geissler S, Duda GN.

Biomaterials. 2015;53:502-21. doi: 10.1016/j.biomaterials.2015.02.110. Epub 2015 Mar 21. Review.


Additive effects of lupin protein and phytic acid on aortic calcification in ApoE deficient mice.

Schutkowski A, Hirche F, Geissler S, Radtke J, Stangl GI.

J Clin Transl Endocrinol. 2014 Nov 29;2(1):6-13. doi: 10.1016/j.jcte.2014.07.007. eCollection 2015 Mar.


Interaction of age and mechanical stability on bone defect healing: an early transcriptional analysis of fracture hematoma in rat.

Ode A, Duda GN, Geissler S, Pauly S, Ode JE, Perka C, Strube P.

PLoS One. 2014 Sep 4;9(9):e106462. doi: 10.1371/journal.pone.0106462. eCollection 2014.


MALDI imaging mass spectrometry: discrimination of pathophysiological regions in traumatized skeletal muscle by characteristic peptide signatures.

Klein O, Strohschein K, Nebrich G, Oetjen J, Trede D, Thiele H, Alexandrov T, Giavalisco P, Duda GN, von Roth P, Geissler S, Klose J, Winkler T.

Proteomics. 2014 Oct;14(20):2249-60. doi: 10.1002/pmic.201400088. Epub 2014 Aug 21. Erratum in: Proteomics. 2014 Nov;14(21-22):2630.


Amino-polyvinyl alcohol coated superparamagnetic iron oxide nanoparticles are suitable for monitoring of human mesenchymal stromal cells in vivo.

Schulze F, Dienelt A, Geissler S, Zaslansky P, Schoon J, Henzler K, Guttmann P, Gramoun A, Crowe LA, Maurizi L, Vallée JP, Hofmann H, Duda GN, Ode A.

Small. 2014 Nov 12;10(21):4340-51. doi: 10.1002/smll.201400707. Epub 2014 Jul 2.


Qualifying stem cell sources: how to overcome potential pitfalls in regenerative medicine?

Reinke S, Dienelt A, Blankenstein A, Duda GN, Geissler S.

J Tissue Eng Regen Med. 2016 Jan;10(1):3-10. doi: 10.1002/term.1923. Epub 2014 Jun 12. Review.


Lupin protein isolate versus casein modifies cholesterol excretion and mRNA expression of intestinal sterol transporters in a pig model.

Radtke J, Geissler S, Schutkowski A, Brandsch C, Kluge H, Duranti MM, Keller S, Jahreis G, Hirche F, Stangl GI.

Nutr Metab (Lond). 2014 Feb 3;11(1):9. doi: 10.1186/1743-7075-11-9.


In serum veritas-in serum sanitas? Cell non-autonomous aging compromises differentiation and survival of mesenchymal stromal cells via the oxidative stress pathway.

Geissler S, Textor M, Schmidt-Bleek K, Klein O, Thiele M, Ellinghaus A, Jacobi D, Ode A, Perka C, Dienelt A, Klose J, Kasper G, Duda GN, Strube P.

Cell Death Dis. 2013 Dec 19;4:e970. doi: 10.1038/cddis.2013.501.

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