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Items: 1 to 50 of 81

1.

Abrogation of Stem Loop Binding Protein (Slbp) function leads to a failure of cells to transition from proliferation to differentiation, retinal coloboma and midline axon guidance deficits.

Turner KJ, Hoyle J, Valdivia LE, Cerveny KL, Hart W, Mangoli M, Geisler R, Rees M, Houart C, Poole RJ, Wilson SW, Gestri G.

PLoS One. 2019 Jan 29;14(1):e0211073. doi: 10.1371/journal.pone.0211073. eCollection 2019.

2.

Mutation of a serine near the catalytic site of the choline acetyltransferase a gene almost completely abolishes motility of the zebrafish embryo.

Joshi S, Virdi S, Etard C, Geisler R, Strähle U.

PLoS One. 2018 Nov 20;13(11):e0207747. doi: 10.1371/journal.pone.0207747. eCollection 2018.

3.

Report of Workshop on Euthanasia for Zebrafish-A Matter of Welfare and Science.

Köhler A, Collymore C, Finger-Baier K, Geisler R, Kaufmann L, Pounder KC, Schulte-Merker S, Valentim A, Varga ZM, Weiss J, Strähle U.

Zebrafish. 2017 Dec;14(6):547-551. doi: 10.1089/zeb.2017.1508. Epub 2017 Oct 2.

4.

The Calcineurin-FoxO-MuRF1 signaling pathway regulates myofibril integrity in cardiomyocytes.

Shimizu H, Langenbacher AD, Huang J, Wang K, Otto G, Geisler R, Wang Y, Chen JN.

Elife. 2017 Aug 19;6. pii: e27955. doi: 10.7554/eLife.27955.

5.

The impact of pharmacy monitoring and intervention in patients receiving intravenous heparin.

Lysogorski MC, Hassan AK, Lampkin SJ, Geisler R.

Int J Clin Pharm. 2017 Aug;39(4):844-850. doi: 10.1007/s11096-017-0482-y. Epub 2017 May 15.

PMID:
28508323
6.

Archiving of zebrafish lines can reduce animal experiments in biomedical research.

Geisler R, Köhler A, Dickmeis T, Strähle U.

EMBO Rep. 2017 Jan;18(1):1-2. doi: 10.15252/embr.201643561. Epub 2016 Dec 15. No abstract available.

7.

Maintenance of Zebrafish Lines at the European Zebrafish Resource Center.

Geisler R, Borel N, Ferg M, Maier JV, Strähle U.

Zebrafish. 2016 Jul;13 Suppl 1:S19-23. doi: 10.1089/zeb.2015.1205.

8.

Spermidine, but not spermine, is essential for pigment pattern formation in zebrafish.

Frohnhöfer HG, Geiger-Rudolph S, Pattky M, Meixner M, Huhn C, Maischein HM, Geisler R, Gehring I, Maderspacher F, Nüsslein-Volhard C, Irion U.

Biol Open. 2016 Jun 15;5(6):736-44. doi: 10.1242/bio.018721.

9.

pigk Mutation underlies macho behavior and affects Rohon-Beard cell excitability.

Carmean V, Yonkers MA, Tellez MB, Willer JR, Willer GB, Gregg RG, Geisler R, Neuhauss SC, Ribera AB.

J Neurophysiol. 2015 Aug;114(2):1146-57. doi: 10.1152/jn.00355.2015. Epub 2015 Jul 1.

10.

The complex aerodynamic footprint of desert locusts revealed by large-volume tomographic particle image velocimetry.

Henningsson P, Michaelis D, Nakata T, Schanz D, Geisler R, Schröder A, Bomphrey RJ.

J R Soc Interface. 2015 Jul 6;12(108):20150119. doi: 10.1098/rsif.2015.0119.

11.

The zebrafish reference genome sequence and its relationship to the human genome.

Howe K, Clark MD, Torroja CF, Torrance J, Berthelot C, Muffato M, Collins JE, Humphray S, McLaren K, Matthews L, McLaren S, Sealy I, Caccamo M, Churcher C, Scott C, Barrett JC, Koch R, Rauch GJ, White S, Chow W, Kilian B, Quintais LT, Guerra-Assunção JA, Zhou Y, Gu Y, Yen J, Vogel JH, Eyre T, Redmond S, Banerjee R, Chi J, Fu B, Langley E, Maguire SF, Laird GK, Lloyd D, Kenyon E, Donaldson S, Sehra H, Almeida-King J, Loveland J, Trevanion S, Jones M, Quail M, Willey D, Hunt A, Burton J, Sims S, McLay K, Plumb B, Davis J, Clee C, Oliver K, Clark R, Riddle C, Elliot D, Threadgold G, Harden G, Ware D, Begum S, Mortimore B, Kerry G, Heath P, Phillimore B, Tracey A, Corby N, Dunn M, Johnson C, Wood J, Clark S, Pelan S, Griffiths G, Smith M, Glithero R, Howden P, Barker N, Lloyd C, Stevens C, Harley J, Holt K, Panagiotidis G, Lovell J, Beasley H, Henderson C, Gordon D, Auger K, Wright D, Collins J, Raisen C, Dyer L, Leung K, Robertson L, Ambridge K, Leongamornlert D, McGuire S, Gilderthorp R, Griffiths C, Manthravadi D, Nichol S, Barker G, Whitehead S, Kay M, Brown J, Murnane C, Gray E, Humphries M, Sycamore N, Barker D, Saunders D, Wallis J, Babbage A, Hammond S, Mashreghi-Mohammadi M, Barr L, Martin S, Wray P, Ellington A, Matthews N, Ellwood M, Woodmansey R, Clark G, Cooper J, Tromans A, Grafham D, Skuce C, Pandian R, Andrews R, Harrison E, Kimberley A, Garnett J, Fosker N, Hall R, Garner P, Kelly D, Bird C, Palmer S, Gehring I, Berger A, Dooley CM, Ersan-Ürün Z, Eser C, Geiger H, Geisler M, Karotki L, Kirn A, Konantz J, Konantz M, Oberländer M, Rudolph-Geiger S, Teucke M, Lanz C, Raddatz G, Osoegawa K, Zhu B, Rapp A, Widaa S, Langford C, Yang F, Schuster SC, Carter NP, Harrow J, Ning Z, Herrero J, Searle SM, Enright A, Geisler R, Plasterk RH, Lee C, Westerfield M, de Jong PJ, Zon LI, Postlethwait JH, Nüsslein-Volhard C, Hubbard TJ, Roest Crollius H, Rogers J, Stemple DL.

Nature. 2013 Apr 25;496(7446):498-503. doi: 10.1038/nature12111. Epub 2013 Apr 17. Erratum in: Nature. 2014 Jan 9;505(7482):248. Cooper, James [corrected to Cooper, James D]; Eliott, David [corrected to Elliot, David]; Mortimer, Beverly [corrected to Mortimore, Beverley]; Begum, Sharmin [added]; Lloyd, Christine [added]; Lanz, Christa [added]; Raddatz, Günter [added]; Schuster, Ste.

12.

Slc45a2 and V-ATPase are regulators of melanosomal pH homeostasis in zebrafish, providing a mechanism for human pigment evolution and disease.

Dooley CM, Schwarz H, Mueller KP, Mongera A, Konantz M, Neuhauss SC, Nüsslein-Volhard C, Geisler R.

Pigment Cell Melanoma Res. 2013 Mar;26(2):205-17. doi: 10.1111/pcmr.12053. Epub 2012 Dec 20.

PMID:
23205854
13.

EuFishBioMed (COST Action BM0804): a European network to promote the use of small fishes in biomedical research.

Strähle U, Bally-Cuif L, Kelsh R, Beis D, Mione M, Panula P, Figueras A, Gothilf Y, Brösamle C, Geisler R, Knedlitschek G.

Zebrafish. 2012 Jun;9(2):90-3. doi: 10.1089/zeb.2012.0742. Epub 2012 Apr 26.

14.

Zebrafish embryos as an alternative to animal experiments--a commentary on the definition of the onset of protected life stages in animal welfare regulations.

Strähle U, Scholz S, Geisler R, Greiner P, Hollert H, Rastegar S, Schumacher A, Selderslaghs I, Weiss C, Witters H, Braunbeck T.

Reprod Toxicol. 2012 Apr;33(2):128-32. doi: 10.1016/j.reprotox.2011.06.121. Epub 2011 Jun 25. Review.

PMID:
21726626
15.

Fine-tuning of Hh signaling by the RNA-binding protein Quaking to control muscle development.

Lobbardi R, Lambert G, Zhao J, Geisler R, Kim HR, Rosa FM.

Development. 2011 May;138(9):1783-94. doi: 10.1242/dev.059121. Epub 2011 Mar 29.

16.

The light responsive transcriptome of the zebrafish: function and regulation.

Weger BD, Sahinbas M, Otto GW, Mracek P, Armant O, Dolle D, Lahiri K, Vallone D, Ettwiller L, Geisler R, Foulkes NS, Dickmeis T.

PLoS One. 2011 Feb 15;6(2):e17080. doi: 10.1371/journal.pone.0017080.

17.

Aplexone targets the HMG-CoA reductase pathway and differentially regulates arteriovenous angiogenesis.

Choi J, Mouillesseaux K, Wang Z, Fiji HD, Kinderman SS, Otto GW, Geisler R, Kwon O, Chen JN.

Development. 2011 Mar;138(6):1173-81. doi: 10.1242/dev.054049. Epub 2011 Feb 9.

18.

The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation.

Becker-Heck A, Zohn IE, Okabe N, Pollock A, Lenhart KB, Sullivan-Brown J, McSheene J, Loges NT, Olbrich H, Haeffner K, Fliegauf M, Horvath J, Reinhardt R, Nielsen KG, Marthin JK, Baktai G, Anderson KV, Geisler R, Niswander L, Omran H, Burdine RD.

Nat Genet. 2011 Jan;43(1):79-84. doi: 10.1038/ng.727. Epub 2010 Dec 5.

19.

The zebrafish mutant bumper shows a hyperproliferation of lens epithelial cells and fibre cell degeneration leading to functional blindness.

Schonthaler HB, Franz-Odendaal TA, Hodel C, Gehring I, Geisler R, Schwarz H, Neuhauss SC, Dahm R.

Mech Dev. 2010 Apr;127(3-4):203-19. doi: 10.1016/j.mod.2010.01.005. Epub 2010 Feb 1.

20.

The zebrafish dystrophic mutant softy maintains muscle fibre viability despite basement membrane rupture and muscle detachment.

Jacoby AS, Busch-Nentwich E, Bryson-Richardson RJ, Hall TE, Berger J, Berger S, Sonntag C, Sachs C, Geisler R, Stemple DL, Currie PD.

Development. 2009 Oct;136(19):3367-76. doi: 10.1242/dev.034561.

21.

Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration.

Kizil C, Otto GW, Geisler R, Nüsslein-Volhard C, Antos CL.

Dev Biol. 2009 Jan 15;325(2):329-40. doi: 10.1016/j.ydbio.2008.09.032. Epub 2008 Oct 17.

22.

Leukocyte tyrosine kinase functions in pigment cell development.

Lopes SS, Yang X, Müller J, Carney TJ, McAdow AR, Rauch GJ, Jacoby AS, Hurst LD, Delfino-Machín M, Haffter P, Geisler R, Johnson SL, Ward A, Kelsh RN.

PLoS Genet. 2008 Mar 7;4(3):e1000026. doi: 10.1371/journal.pgen.1000026.

23.

Investigator profile. An interview with Robert Geisler, Ph.D. Interview by Vicki Glaser.

Geisler R.

Zebrafish. 2005;2(4):237-41. doi: 10.1089/zeb.2005.2.237.

PMID:
18248182
24.

The zebrafish mutant lbk/vam6 resembles human multisystemic disorders caused by aberrant trafficking of endosomal vesicles.

Schonthaler HB, Fleisch VC, Biehlmaier O, Makhankov Y, Rinner O, Bahadori R, Geisler R, Schwarz H, Neuhauss SC, Dahm R.

Development. 2008 Jan;135(2):387-99. Epub 2007 Dec 12.

25.

Radiation hybrid maps of Medaka chromosomes LG 12, 17, and 22.

Su F, Osada Y, Ekker M, Chevrette M, Shimizu A, Asakawa S, Shiohama A, Sasaki T, Shimizu N, Yamanaka T, Sasado T, Mitani H, Geisler R, Kondoh H, Furutani-Seiki M.

DNA Res. 2007 Jun 30;14(3):135-40. Epub 2007 Jun 25.

26.

The UCS factor Steif/Unc-45b interacts with the heat shock protein Hsp90a during myofibrillogenesis.

Etard C, Behra M, Fischer N, Hutcheson D, Geisler R, Strähle U.

Dev Biol. 2007 Aug 1;308(1):133-43. Epub 2007 May 18.

27.

Cohesin-dependent regulation of Runx genes.

Horsfield JA, Anagnostou SH, Hu JK, Cho KH, Geisler R, Lieschke G, Crosier KE, Crosier PS.

Development. 2007 Jul;134(14):2639-49. Epub 2007 Jun 13.

28.

Assessment of inter-observer reliability of two five-level triage and acuity scales: a randomized controlled trial.

Worster A, Gilboy N, Fernandes CM, Eitel D, Eva K, Geisler R, Tanabe P.

CJEM. 2004 Jul;6(4):240-5.

PMID:
17381999
29.

The zebrafish udu gene encodes a novel nuclear factor and is essential for primitive erythroid cell development.

Liu Y, Du L, Osato M, Teo EH, Qian F, Jin H, Zhen F, Xu J, Guo L, Huang H, Chen J, Geisler R, Jiang YJ, Peng J, Wen Z.

Blood. 2007 Jul 1;110(1):99-106. Epub 2007 Mar 16.

30.

Differential gene expression as a toxicant-sensitive endpoint in zebrafish embryos and larvae.

Voelker D, Vess C, Tillmann M, Nagel R, Otto GW, Geisler R, Schirmer K, Scholz S.

Aquat Toxicol. 2007 Mar 30;81(4):355-64. Epub 2007 Jan 12.

PMID:
17292976
31.

A gene-based radiation hybrid map of the gilthead sea bream Sparus aurata refines and exploits conserved synteny with Tetraodon nigroviridis.

Sarropoulou E, Franch R, Louro B, Power DM, Bargelloni L, Magoulas A, Senger F, Tsalavouta M, Patarnello T, Galibert F, Kotoulas G, Geisler R.

BMC Genomics. 2007 Feb 7;8:44.

32.

Optic cavitation in an ultrasonic field.

Kurz T, Kröninger D, Geisler R, Lauterborn W.

Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Dec;74(6 Pt 2):066307. Epub 2006 Dec 12.

PMID:
17280148
33.

Acoustic cavitation, bubble dynamics and sonoluminescence.

Lauterborn W, Kurz T, Geisler R, Schanz D, Lindau O.

Ultrason Sonochem. 2007 Apr;14(4):484-91. Epub 2007 Jan 24.

PMID:
17254826
34.

Large-scale mapping of mutations affecting zebrafish development.

Geisler R, Rauch GJ, Geiger-Rudolph S, Albrecht A, van Bebber F, Berger A, Busch-Nentwich E, Dahm R, Dekens MP, Dooley C, Elli AF, Gehring I, Geiger H, Geisler M, Glaser S, Holley S, Huber M, Kerr A, Kirn A, Knirsch M, Konantz M, Küchler AM, Maderspacher F, Neuhauss SC, Nicolson T, Ober EA, Praeg E, Ray R, Rentzsch B, Rick JM, Rief E, Schauerte HE, Schepp CP, Schönberger U, Schonthaler HB, Seiler C, Sidi S, Söllner C, Wehner A, Weiler C, Nüsslein-Volhard C.

BMC Genomics. 2007 Jan 9;8:11.

35.

Learning from small fry: the zebrafish as a genetic model organism for aquaculture fish species.

Dahm R, Geisler R.

Mar Biotechnol (NY). 2006 Jul-Aug;8(4):329-45. Epub 2006 Apr 25. Review.

PMID:
16670967
36.

The first radiation hybrid map of a perch-like fish: the gilthead seabream (Sparus aurata L).

Senger F, Priat C, Hitte C, Sarropoulou E, Franch R, Geisler R, Bargelloni L, Power D, Galibert F.

Genomics. 2006 Jun;87(6):793-800. Epub 2006 Jan 18.

37.

Mutation in the delta-subunit of the nAChR suppresses the muscle defects caused by lack of Dystrophin.

Etard C, Behra M, Ertzer R, Fischer N, Jesuthasan S, Blader P, Geisler R, Strähle U.

Dev Dyn. 2005 Dec;234(4):1016-25.

38.

beamter/deltaC and the role of Notch ligands in the zebrafish somite segmentation, hindbrain neurogenesis and hypochord differentiation.

Jülich D, Hwee Lim C, Round J, Nicolaije C, Schroeder J, Davies A, Geisler R, Lewis J, Jiang YJ, Holley SA; Tübingen 2000 Screen Consortium.

Dev Biol. 2005 Oct 15;286(2):391-404. Epub 2005 Aug 26.

39.

The zebrafish mutants dre, uki, and lep encode negative regulators of the hedgehog signaling pathway.

Koudijs MJ, den Broeder MJ, Keijser A, Wienholds E, Houwing S, van Rooijen EM, Geisler R, van Eeden FJ.

PLoS Genet. 2005 Aug;1(2):e19. Epub 2005 Aug 19.

40.

Gene expression profiling of gilthead sea bream during early development and detection of stress-related genes by the application of cDNA microarray technology.

Sarropoulou E, Kotoulas G, Power DM, Geisler R.

Physiol Genomics. 2005 Oct 17;23(2):182-91. Epub 2005 Jul 26.

PMID:
16046618
41.

A mutation in the silver gene leads to defects in melanosome biogenesis and alterations in the visual system in the zebrafish mutant fading vision.

Schonthaler HB, Lampert JM, von Lintig J, Schwarz H, Geisler R, Neuhauss SC.

Dev Biol. 2005 Aug 15;284(2):421-36.

42.

The zebrafish shocked gene encodes a glycine transporter and is essential for the function of early neural circuits in the CNS.

Cui WW, Low SE, Hirata H, Saint-Amant L, Geisler R, Hume RI, Kuwada JY.

J Neurosci. 2005 Jul 13;25(28):6610-20.

43.

Zebrafish penner/lethal giant larvae 2 functions in hemidesmosome formation, maintenance of cellular morphology and growth regulation in the developing basal epidermis.

Sonawane M, Carpio Y, Geisler R, Schwarz H, Maischein HM, Nuesslein-Volhard C.

Development. 2005 Jul;132(14):3255-65.

44.

Histone deacetylase 1 is required for cell cycle exit and differentiation in the zebrafish retina.

Stadler JA, Shkumatava A, Norton WH, Rau MJ, Geisler R, Fischer S, Neumann CJ.

Dev Dyn. 2005 Jul;233(3):883-9.

45.

Transcriptome profiling of adult zebrafish at the late stage of chronic tuberculosis due to Mycobacterium marinum infection.

Meijer AH, Verbeek FJ, Salas-Vidal E, Corredor-Adámez M, Bussman J, van der Sar AM, Otto GW, Geisler R, Spaink HP.

Mol Immunol. 2005 Jun;42(10):1185-203. Epub 2005 Jan 12.

PMID:
15829308
46.

Integrinalpha5 and delta/notch signaling have complementary spatiotemporal requirements during zebrafish somitogenesis.

Jülich D, Geisler R, Holley SA; Tübingen 2000 Screen Consortium.

Dev Cell. 2005 Apr;8(4):575-86.

47.

Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphé neurones and cranial motoneurones.

Norton WH, Mangoli M, Lele Z, Pogoda HM, Diamond B, Mercurio S, Russell C, Teraoka H, Stickney HL, Rauch GJ, Heisenberg CP, Houart C, Schilling TF, Frohnhoefer HG, Rastegar S, Neumann CJ, Gardiner RM, Strähle U, Geisler R, Rees M, Talbot WS, Wilson SW.

Development. 2005 Feb;132(4):645-58.

48.

Axon sorting in the optic tract requires HSPG synthesis by ext2 (dackel) and extl3 (boxer).

Lee JS, von der Hardt S, Rusch MA, Stringer SE, Stickney HL, Talbot WS, Geisler R, Nüsslein-Volhard C, Selleck SB, Chien CB, Roehl H.

Neuron. 2004 Dec 16;44(6):947-60.

49.

Mutated otopetrin 1 affects the genesis of otoliths and the localization of Starmaker in zebrafish.

Söllner C, Schwarz H, Geisler R, Nicolson T.

Dev Genes Evol. 2004 Dec;214(12):582-90. Epub 2004 Oct 5.

PMID:
15480759
50.

iguana encodes a novel zinc-finger protein with coiled-coil domains essential for Hedgehog signal transduction in the zebrafish embryo.

Wolff C, Roy S, Lewis KE, Schauerte H, Joerg-Rauch G, Kirn A, Weiler C, Geisler R, Haffter P, Ingham PW.

Genes Dev. 2004 Jul 1;18(13):1565-76. Epub 2004 Jun 15.

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