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Items: 1 to 50 of 266

1.

Disease modifying mitochondrial uncouplers, MP101, and a slow release ProDrug, MP201, in models of Multiple Sclerosis.

Bando Y, Geisler JG.

Neurochem Int. 2019 Oct 1:104561. doi: 10.1016/j.neuint.2019.104561. [Epub ahead of print]

PMID:
31585135
2.

The NEOLETEXE trial: a neoadjuvant cross-over study exploring the lack of cross resistance between aromatase inhibitors.

Bahrami N, Sauer T, Engebretsen S, Aljabri B, Bemanian V, Lindstrøm J, Lüders T, Kristensen V, Lorentzen A, Loeng M, Ødegård HP, Kvaløy JØ, Vestøl IB, Geisler SB, Gravdehaug B, Gundersen JM, Geisler J.

Future Oncol. 2019 Sep 12. doi: 10.2217/fon-2019-0258. [Epub ahead of print]

3.

The emerging role of human cytomegalovirus infection in human carcinogenesis: a review of current evidence and potential therapeutic implications.

Nauclér CS, Geisler J, Vetvik K.

Oncotarget. 2019 Jul 2;10(42):4333-4347. doi: 10.18632/oncotarget.27016. eCollection 2019 Jul 2. Review.

4.

The NAME trial: a direct comparison of classical oral Navelbine versus Metronomic Navelbine in metastatic breast cancer.

Langkjer ST, Kenholm J, Jensen JD, Wedervang K, Brixen AT, Grunnet M, Stenbygaard L, Gilje B, Danø H, Glavicic V, Jacobsen EH, Brems-Eskildsen AS, Kruse HL, Dongsgaard T, Neimann J, Geisler J.

Future Oncol. 2019 Aug;15(22):2561-2569. doi: 10.2217/fon-2019-0124. Epub 2019 Jun 19.

5.

Human cytomegalovirus infection is correlated with enhanced cyclooxygenase-2 and 5-lipoxygenase protein expression in breast cancer.

Costa H, Touma J, Davoudi B, Benard M, Sauer T, Geisler J, Vetvik K, Rahbar A, Söderberg-Naucler C.

J Cancer Res Clin Oncol. 2019 Aug;145(8):2083-2095. doi: 10.1007/s00432-019-02946-8. Epub 2019 Jun 15.

6.

Evidence for convergent evolution of ultrasonic hearing in toothed whales (Cetacea: Odontoceti).

Racicot RA, Boessenecker RW, Darroch SAF, Geisler JH.

Biol Lett. 2019 May 31;15(5):20190083. doi: 10.1098/rsbl.2019.0083.

PMID:
31088283
7.

Whale Evolution: Dispersal by Paddle or Fluke.

Geisler JH.

Curr Biol. 2019 Apr 22;29(8):R294-R296. doi: 10.1016/j.cub.2019.03.005.

PMID:
31014490
8.

2,4 Dinitrophenol as Medicine.

Geisler JG.

Cells. 2019 Mar 23;8(3). pii: E280. doi: 10.3390/cells8030280. Review.

9.

PEPCK1 Antisense Oligonucleotide Prevents Adiposity and Impairs Hepatic Glycogen Synthesis in High-Fat Male Fed Rats.

Beddow SA, Gattu AK, Vatner DF, Paolella L, Alqarzaee A, Tashkandi N, Popov VB, Church CD, Rodeheffer MS, Cline GW, Geisler JG, Bhanot S, Samuel VT.

Endocrinology. 2019 Jan 1;160(1):205-219. doi: 10.1210/en.2018-00630.

PMID:
30445425
10.
11.

Somatic EP300-G211S mutations are associated with overall somatic mutational patterns and breast cancer specific survival in triple-negative breast cancer.

Bemanian V, Noone JC, Sauer T, Touma J, Vetvik K, Søderberg-Naucler C, Lindstrøm JC, Bukholm IR, Kristensen VN, Geisler J.

Breast Cancer Res Treat. 2018 Nov;172(2):339-351. doi: 10.1007/s10549-018-4927-3. Epub 2018 Aug 21.

PMID:
30132219
12.

Mitochondrial uncoupling prodrug improves tissue sparing, cognitive outcome, and mitochondrial bioenergetics after traumatic brain injury in male mice.

Hubbard WB, Harwood CL, Geisler JG, Vekaria HJ, Sullivan PG.

J Neurosci Res. 2018 Oct;96(10):1677-1688. doi: 10.1002/jnr.24271. Epub 2018 Jul 31.

13.

Patterns of genomic evolution in advanced melanoma.

Birkeland E, Zhang S, Poduval D, Geisler J, Nakken S, Vodak D, Meza-Zepeda LA, Hovig E, Myklebost O, Knappskog S, Lønning PE.

Nat Commun. 2018 Jul 10;9(1):2665. doi: 10.1038/s41467-018-05063-1.

14.

Prevention of Underage Drinking on California Indian Reservations Using Individual- and Community-Level Approaches.

Moore RS, Gilder DA, Grube JW, Lee JP, Geisler JA, Friese B, Calac DJ, Finan LJ, Ehlers CL.

Am J Public Health. 2018 Aug;108(8):1035-1041. doi: 10.2105/AJPH.2018.304447. Epub 2018 Jun 21.

15.

Evolution: More Mysticete Mysteries.

Geisler JH.

Curr Biol. 2018 May 21;28(10):R603-R605. doi: 10.1016/j.cub.2018.04.049.

16.

Evolution of cranial telescoping in echolocating whales (Cetacea: Odontoceti).

Churchill M, Geisler JH, Beatty BL, Goswami A.

Evolution. 2018 May;72(5):1092-1108. doi: 10.1111/evo.13480. Epub 2018 Apr 25.

PMID:
29624668
17.

Enhancer variants reveal a conserved transcription factor network governed by PU.1 during osteoclast differentiation.

Carey HA, Hildreth BE 3rd, Geisler JA, Nickel MC, Cabrera J, Ghosh S, Jiang Y, Yan J, Lee J, Makam S, Young NA, Valiente GR, Jarjour WN, Huang K, Rosol TJ, Toribio RE, Charles JF, Ostrowski MC, Sharma SM.

Bone Res. 2018 Mar 28;6:8. doi: 10.1038/s41413-018-0011-1. eCollection 2018.

18.

In breast cancer subtypes steroid sulfatase (STS) is associated with less aggressive tumour characteristics.

McNamara KM, Guestini F, Sauer T, Touma J, Bukholm IR, Lindstrøm JC, Sasano H, Geisler J.

Br J Cancer. 2018 May;118(9):1208-1216. doi: 10.1038/s41416-018-0034-9. Epub 2018 Mar 22.

19.

Neurohormonal Blockade and Circulating Cardiovascular Biomarkers During Anthracycline Therapy in Breast Cancer Patients: Results From the PRADA (Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy) Study.

Gulati G, Heck SL, Røsjø H, Ree AH, Hoffmann P, Hagve TA, Norseth J, Gravdehaug B, Steine K, Geisler J, Omland T.

J Am Heart Assoc. 2017 Nov 8;6(11). pii: e006513. doi: 10.1161/JAHA.117.006513.

20.
21.

Effect of candesartan and metoprolol on myocardial tissue composition during anthracycline treatment: the PRADA trial.

Heck SL, Gulati G, Hoffmann P, von Knobelsdorff-Brenkenhoff F, Storås TH, Ree AH, Gravdehaug B, Røsjø H, Steine K, Geisler J, Schulz-Menger J, Omland T.

Eur Heart J Cardiovasc Imaging. 2018 May 1;19(5):544-552. doi: 10.1093/ehjci/jex159.

PMID:
29106497
22.

A pilot randomized trial of Motivational Interviewing compared to Psycho-Education for reducing and preventing underage drinking in American Indian adolescents.

Gilder DA, Geisler JR, Luna JA, Calac D, Monti PM, Spillane NS, Lee JP, Moore RS, Ehlers CL.

J Subst Abuse Treat. 2017 Nov;82:74-81. doi: 10.1016/j.jsat.2017.09.004. Epub 2017 Sep 9.

23.

A toothless dwarf dolphin (Odontoceti: Xenorophidae) points to explosive feeding diversification of modern whales (Neoceti).

Boessenecker RW, Fraser D, Churchill M, Geisler JH.

Proc Biol Sci. 2017 Aug 30;284(1861). pii: 20170531. doi: 10.1098/rspb.2017.0531.

24.

Indazole-based ligands for estrogen-related receptor α as potential anti-diabetic agents.

Patch RJ, Huang H, Patel S, Cheung W, Xu G, Zhao BP, Beauchamp DA, Rentzeperis D, Geisler JG, Askari HB, Liu J, Kasturi J, Towers M, Gaul MD, Player MR.

Eur J Med Chem. 2017 Sep 29;138:830-853. doi: 10.1016/j.ejmech.2017.07.015. Epub 2017 Jul 14.

PMID:
28735214
25.

Mitochondrial Uncoupler Prodrug of 2,4-Dinitrophenol, MP201, Prevents Neuronal Damage and Preserves Vision in Experimental Optic Neuritis.

Khan RS, Dine K, Geisler JG, Shindler KS.

Oxid Med Cell Longev. 2017;2017:7180632. doi: 10.1155/2017/7180632. Epub 2017 Jun 7.

26.

The Origin of Filter Feeding in Whales.

Geisler JH, Boessenecker RW, Brown M, Beatty BL.

Curr Biol. 2017 Jul 10;27(13):2036-2042.e2. doi: 10.1016/j.cub.2017.06.003. Epub 2017 Jun 29.

27.

Evolution: Hearing and Feeding in Fossil Whales.

Geisler JH.

Curr Biol. 2017 Jun 19;27(12):R596-R598. doi: 10.1016/j.cub.2017.05.007.

28.

Low Expression of Estrogen Receptor-α and Progesterone Receptor in Human Breast Cancer Tissues Is Associated With High-Grade Human Cytomegalovirus Protein Expression.

Rahbar A, Touma J, Costa H, Davoudi B, Bukholm IR, Sauer T, Vetvik K, Geisler J, Söderberg-Naucler C.

Clin Breast Cancer. 2017 Nov;17(7):526-535.e1. doi: 10.1016/j.clbc.2017.04.013. Epub 2017 May 11.

PMID:
28595965
29.

WITHDRAWN: A randomized trial of motivational interviewing for the prevention of underage drinking in American Indian adolescents.

Gilder DA, Geisler JR, Luna JA, Calac D, Monti PM, Spillane NS, Lee JP, Moore RS, Ehlers CL.

J Subst Abuse Treat. 2017 Apr 23. pii: S0740-5472(17)30170-8. doi: 10.1016/j.jsat.2017.04.015. [Epub ahead of print] No abstract available.

PMID:
28487187
30.

2,4 DNP improves motor function, preserves medium spiny neuronal identity, and reduces oxidative stress in a mouse model of Huntington's disease.

Wu B, Jiang M, Peng Q, Li G, Hou Z, Milne GL, Mori S, Alonso R, Geisler JG, Duan W.

Exp Neurol. 2017 Jul;293:83-90. doi: 10.1016/j.expneurol.2017.03.020. Epub 2017 Mar 28.

PMID:
28359739
31.

Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome.

Aure MR, Vitelli V, Jernström S, Kumar S, Krohn M, Due EU, Haukaas TH, Leivonen SK, Vollan HK, Lüders T, Rødland E, Vaske CJ, Zhao W, Møller EK, Nord S, Giskeødegård GF, Bathen TF, Caldas C, Tramm T, Alsner J, Overgaard J, Geisler J, Bukholm IR, Naume B, Schlichting E, Sauer T, Mills GB, Kåresen R, Mælandsmo GM, Lingjærde OC, Frigessi A, Kristensen VN, Børresen-Dale AL, Sahlberg KK; OSBREAC.

Breast Cancer Res. 2017 Mar 29;19(1):44. doi: 10.1186/s13058-017-0812-y.

32.

Cotargeting of CYP-19 (aromatase) and emerging, pivotal signalling pathways in metastatic breast cancer.

Daldorff S, Mathiesen RM, Yri OE, Ødegård HP, Geisler J.

Br J Cancer. 2017 Jan 3;116(1):10-20. doi: 10.1038/bjc.2016.405. Epub 2016 Dec 6. Review.

33.

The High Prevalence of Functional Complement Defects Induced by Chemotherapy.

Keizer MP, Kamp AM, Aarts C, Geisler J, Caron HN, van de Wetering MD, Wouters D, Kuijpers TW.

Front Immunol. 2016 Oct 17;7:420. eCollection 2016.

34.

DNP, mitochondrial uncoupling, and neuroprotection: A little dab'll do ya.

Geisler JG, Marosi K, Halpern J, Mattson MP.

Alzheimers Dement. 2017 May;13(5):582-591. doi: 10.1016/j.jalz.2016.08.001. Epub 2016 Sep 4.

35.

The Origin of High-Frequency Hearing in Whales.

Churchill M, Martinez-Caceres M, de Muizon C, Mnieckowski J, Geisler JH.

Curr Biol. 2016 Aug 22;26(16):2144-9. doi: 10.1016/j.cub.2016.06.004. Epub 2016 Aug 4.

36.

Discovery of novel potent imidazo[1,2-b]pyridazine PDE10a inhibitors.

Meegalla SK, Huang H, Illig CR, Parks DJ, Chen J, Lee YK, Wilson KJ, Patel SK, Cheung WS, Lu T, Kirchner T, Askari HB, Geisler J, Patch RJ, Gibbs AC, Rady B, Connelly M, Player MR.

Bioorg Med Chem Lett. 2016 Sep 1;26(17):4216-22. doi: 10.1016/j.bmcl.2016.07.054. Epub 2016 Jul 25.

PMID:
27491708
37.

Is the routine use of bevacizumab in the treatment of women with advanced or recurrent cancer of the cervix sustainable?

Klag N, Walter AC, Sheely KM, Manahan KJ, Geisler JP.

Clinicoecon Outcomes Res. 2016 Jun 21;8:287-91. doi: 10.2147/CEOR.S71218. eCollection 2016.

38.

An economic analysis of cisplatin alone versus cisplatin doublets in the treatment of women with advanced or recurrent cervical cancer.

McKim A, Walter AC, Sheely KM, Manahan KJ, Geisler JP.

Eur J Gynaecol Oncol. 2016;37(3):353-6.

PMID:
27352563
39.

Treatment with aromatase inhibitors stimulates the expression of epidermal growth factor receptor-1 and neuregulin 1 in ER positive/HER-2/neu non-amplified primary breast cancers.

Flågeng MH, Larionov A, Geisler J, Knappskog S, Prestvik WS, Bjørkøy G, Lilleng PK, Dixon JM, Miller WR, Lønning PE, Mellgren G.

J Steroid Biochem Mol Biol. 2017 Jan;165(Pt B):228-235. doi: 10.1016/j.jsbmb.2016.06.011. Epub 2016 Jun 22.

PMID:
27343990
40.

Vascular endothelial growth factor (VEGF) and cyclooxygenase 2 (COX 2) immunostaining in ovarian cancer.

Whynott RM, Manahan P, Geisler JP.

Eur J Gynaecol Oncol. 2016;37(2):164-6.

PMID:
27172738
41.

Recurrent Pseudomembranous Colitis in an Ovarian Cancer Patient Undergoing Carboplatin Chemotherapy.

Allen VA, Manahan KJ, Geisler JP.

Case Rep Obstet Gynecol. 2016;2016:7540302. doi: 10.1155/2016/7540302. Epub 2016 Mar 8.

42.

Prevention of cardiac dysfunction during adjuvant breast cancer therapy (PRADA): a 2 × 2 factorial, randomized, placebo-controlled, double-blind clinical trial of candesartan and metoprolol.

Gulati G, Heck SL, Ree AH, Hoffmann P, Schulz-Menger J, Fagerland MW, Gravdehaug B, von Knobelsdorff-Brenkenhoff F, Bratland Å, Storås TH, Hagve TA, Røsjø H, Steine K, Geisler J, Omland T.

Eur Heart J. 2016 Jun 1;37(21):1671-80. doi: 10.1093/eurheartj/ehw022. Epub 2016 Feb 21.

43.

Breast Cancer is Common in Women With Ovarian Malignant Mixed Mullerian Tumors.

Whynott RM, Manahan KJ, Geisler JP.

Am J Clin Oncol. 2018 Mar;41(3):286-288. doi: 10.1097/COC.0000000000000266.

PMID:
26757435
44.

Electrosurgical Settings and Vaginal Cuff Complications.

Lawlor ML, Rao R, Manahan KJ, Geisler JP.

JSLS. 2015 Sep-Dec;19(4). pii: e2015.00088. doi: 10.4293/JSLS.2015.00088.

45.

DNA methylation subgroups in melanoma are associated with proliferative and immunological processes.

Lauss M, Ringnér M, Karlsson A, Harbst K, Busch C, Geisler J, Lønning PE, Staaf J, Jönsson G.

BMC Med Genomics. 2015 Nov 6;8:73. doi: 10.1186/s12920-015-0147-4.

46.

Modular Assembly of Allosteric MEK Inhibitor Structural Elements Unravels Potency and Feedback-Modulation Handles.

Hartung IV, Pühler F, Neuhaus R, Scholz A, Siemeister G, Geisler J, Hillig RC, von Ahsen O, Hitchcock M.

ChemMedChem. 2015 Dec;10(12):2004-13. doi: 10.1002/cmdc.201500442. Epub 2015 Nov 6.

PMID:
26541480
47.

The epidermal growth factor receptor (EGFR / HER-1) gatekeeper mutation T790M is present in European patients with early breast cancer.

Bemanian V, Sauer T, Touma J, Lindstedt BA, Chen Y, Ødegård HP, Vetvik KM, Bukholm IR, Geisler J.

PLoS One. 2015 Aug 12;10(8):e0134398. doi: 10.1371/journal.pone.0134398. eCollection 2015.

48.

Cyclin E is overexpressed by clear cell carcinomas of the endometrium and is a prognostic indicator of survival.

Zapiecki K, Manahan KJ, Miller GA, Geisler JP.

Eur J Gynaecol Oncol. 2015;36(2):114-6.

PMID:
26050345
49.

Genome-Wide DNA Methylation Analysis in Melanoma Reveals the Importance of CpG Methylation in MITF Regulation.

Lauss M, Haq R, Cirenajwis H, Phung B, Harbst K, Staaf J, Rosengren F, Holm K, Aine M, Jirström K, Borg Å, Busch C, Geisler J, Lønning PE, Ringnér M, Howlin J, Fisher DE, Jönsson G.

J Invest Dermatol. 2015 Jul;135(7):1820-1828. doi: 10.1038/jid.2015.61. Epub 2015 Feb 23.

50.

[Advanced radioiodine-refractory differentiated thyroid cancer].

Spitzweg C, Auernhammer CJ, Geisler J, Böck S, Heinemann V, Bartenstein P, Göke B.

Dtsch Med Wochenschr. 2015 Feb;140(3):168-71. doi: 10.1055/s-0041-100196. Epub 2015 Feb 6. Review. German. No abstract available.

PMID:
25658401

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