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What happens at the lesion does not stay at the lesion: Transcription-coupled nucleotide excision repair and the effects of DNA damage on transcription in cis and trans.

Geijer ME, Marteijn JA.

DNA Repair (Amst). 2018 Aug 23. pii: S1568-7864(18)30172-1. doi: 10.1016/j.dnarep.2018.08.007. [Epub ahead of print]


DNA damage-induced replication stress results in PA200-proteasome-mediated degradation of acetylated histones.

Mandemaker IK, Geijer ME, Kik I, Bezstarosti K, Rijkers E, Raams A, Janssens RC, Lans H, Hoeijmakers JH, Demmers JA, Vermeulen W, Marteijn JA.

EMBO Rep. 2018 Aug 13. pii: e45566. doi: 10.15252/embr.201745566. [Epub ahead of print]


Live-cell analysis of endogenous GFP-RPB1 uncovers rapid turnover of initiating and promoter-paused RNA Polymerase II.

Steurer B, Janssens RC, Geverts B, Geijer ME, Wienholz F, Theil AF, Chang J, Dealy S, Pothof J, van Cappellen WA, Houtsmuller AB, Marteijn JA.

Proc Natl Acad Sci U S A. 2018 May 8;115(19):E4368-E4376. doi: 10.1073/pnas.1717920115. Epub 2018 Apr 9.

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