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Items: 1 to 50 of 338

1.

The landscape of tiered regulation of breast cancer cell metabolism.

Katzir R, Polat IH, Harel M, Katz S, Foguet C, Selivanov VA, Sabatier P, Cascante M, Geiger T, Ruppin E.

Sci Rep. 2019 Nov 28;9(1):17760. doi: 10.1038/s41598-019-54221-y.

2.

Programmed death-ligand 1 expression influenced by tissue sample size. Scoring based on tissue microarrays' and cross-validation with resections, in patients with, stage I-III, non-small cell lung carcinoma of the European Thoracic Oncology Platform Lungscape cohort.

Thunnissen E, Kerr KM, Dafni U, Bubendorf L, Finn SP, Soltermann A, Biernat W, Cheney R, Verbeken E, Warth A, Marchetti A, Speel EM, Pokharel S, Quinn AM, Monkhorst K, Navarro A, Madsen LB, Tsourti Z, Geiger T, Kammler R, Peters S, Stahel RA; European Thoracic Oncology Platform Lungscape Consortium.

Mod Pathol. 2019 Nov 18. doi: 10.1038/s41379-019-0383-9. [Epub ahead of print]

PMID:
31740722
3.

MicroRNAs Affect Complement Regulator Expression and Mitochondrial Activity to Modulate Cell Resistance to Complement-Dependent Cytotoxicity.

Hillman Y, Mardamshina M, Pasmanik-Chor M, Ziporen L, Geiger T, Shomron N, Fishelson Z.

Cancer Immunol Res. 2019 Dec;7(12):1970-1983. doi: 10.1158/2326-6066.CIR-18-0818. Epub 2019 Sep 19.

PMID:
31537542
4.

Anti-TNF therapy in IBD exerts its therapeutic effect through macrophage IL-10 signalling.

Koelink PJ, Bloemendaal FM, Li B, Westera L, Vogels EWM, van Roest M, Gloudemans AK, van 't Wout AB, Korf H, Vermeire S, Te Velde AA, Ponsioen CY, D'Haens GR, Verbeek JS, Geiger TL, Wildenberg ME, van den Brink GR.

Gut. 2019 Sep 10. pii: gutjnl-2019-318264. doi: 10.1136/gutjnl-2019-318264. [Epub ahead of print]

5.

Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence.

Harel M, Ortenberg R, Varanasi SK, Mangalhara KC, Mardamshina M, Markovits E, Baruch EN, Tripple V, Arama-Chayoth M, Greenberg E, Shenoy A, Ayasun R, Knafo N, Xu S, Anafi L, Yanovich-Arad G, Barnabas GD, Ashkenazi S, Besser MJ, Schachter J, Bosenberg M, Shadel GS, Barshack I, Kaech SM, Markel G, Geiger T.

Cell. 2019 Sep 19;179(1):236-250.e18. doi: 10.1016/j.cell.2019.08.012. Epub 2019 Sep 5.

PMID:
31495571
6.

FKBP51 and FKBP12.6-Novel and tight interactors of Glomulin.

Hähle A, Geiger TM, Merz S, Meyners C, Tianqi M, Kolos J, Hausch F.

PLoS One. 2019 Sep 6;14(9):e0221926. doi: 10.1371/journal.pone.0221926. eCollection 2019.

7.

Preloading budding yeast with all-in-one CRISPR/Cas9 vectors for easy and high-efficient genome editing.

Degreif D, Kremenovic M, Geiger T, Bertl A.

J Biol Methods. 2018 Sep 12;5(3):e98. doi: 10.14440/jbm.2018.254. eCollection 2018.

8.

Ultra-Porous Nanocellulose Foams: A Facile and Scalable Fabrication Approach.

Antonini C, Wu T, Zimmermann T, Kherbeche A, Thoraval MJ, Nyström G, Geiger T.

Nanomaterials (Basel). 2019 Aug 9;9(8). pii: E1142. doi: 10.3390/nano9081142.

9.

CRISPR/Cas9-mediated Knockout of the Neuropsychiatric Risk Gene KCTD13 Causes Developmental Deficits in Human Cortical Neurons Derived from Induced Pluripotent Stem Cells.

Kizner V, Naujock M, Fischer S, Jäger S, Reich S, Schlotthauer I, Zuckschwerdt K, Geiger T, Hildebrandt T, Lawless N, Macartney T, Dorner-Ciossek C, Gillardon F.

Mol Neurobiol. 2019 Aug 11. doi: 10.1007/s12035-019-01727-1. [Epub ahead of print]

PMID:
31402430
10.

Synthesis and Photodimerization of 2- and 2,3-Disubstituted Anthracenes: Influence of Steric Interactions and London Dispersion on Diastereoselectivity.

Geiger T, Haupt A, Maichle-Mössmer C, Schrenk C, Schnepf A, Bettinger HF.

J Org Chem. 2019 Aug 16;84(16):10120-10135. doi: 10.1021/acs.joc.9b01317. Epub 2019 Aug 7.

PMID:
31390211
11.

Proteomic and genomic signatures of repeat instability in cancer and adjacent normal tissues.

Persi E, Prandi D, Wolf YI, Pozniak Y, Barnabas GD, Levanon K, Barshack I, Barbieri C, Gasperini P, Beltran H, Faltas BM, Rubin MA, Geiger T, Koonin EV, Demichelis F, Horn D.

Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):16987-16996. doi: 10.1073/pnas.1908790116. Epub 2019 Aug 6.

PMID:
31387980
12.

Systematic Detection of Amino Acid Substitutions in Proteomes Reveals Mechanistic Basis of Ribosome Errors and Selection for Translation Fidelity.

Mordret E, Dahan O, Asraf O, Rak R, Yehonadav A, Barnabas GD, Cox J, Geiger T, Lindner AB, Pilpel Y.

Mol Cell. 2019 Aug 8;75(3):427-441.e5. doi: 10.1016/j.molcel.2019.06.041. Epub 2019 Jul 25.

PMID:
31353208
13.

Comparing pathologic outcomes for robotic versus laparoscopic Surgery in rectal cancer resection: a propensity adjusted analysis of 7616 patients.

Hopkins MB, Geiger TM, Bethurum AJ, Ford MM, Muldoon RL, Beck DE, Stewart TG, Hawkins AT.

Surg Endosc. 2019 Jul 25. doi: 10.1007/s00464-019-07032-1. [Epub ahead of print]

PMID:
31346754
14.

Impact of delayed and prolonged fixation on the evaluation of immunohistochemical staining on lung carcinoma resection specimen.

van Seijen M, Brcic L, Gonzales AN, Sansano I, Bendek M, Brcic I, Lissenberg-Witte B, Korkmaz HI, Geiger T, Kammler R, Stahel R, Thunnissen E; ETOP.

Virchows Arch. 2019 Aug;475(2):191-199. doi: 10.1007/s00428-019-02595-9. Epub 2019 Jul 1.

15.

Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8+ T cell responses.

Zamora AE, Crawford JC, Allen EK, Guo XJ, Bakke J, Carter RA, Abdelsamed HA, Moustaki A, Li Y, Chang TC, Awad W, Dallas MH, Mullighan CG, Downing JR, Geiger TL, Chen T, Green DR, Youngblood BA, Zhang J, Thomas PG.

Sci Transl Med. 2019 Jun 26;11(498). pii: eaat8549. doi: 10.1126/scitranslmed.aat8549.

PMID:
31243155
16.

Assessing Hereditary Colorectal Cancer Referral Patterns to a Tertiary Care Center: A Novel Approach Using Geographic Information System Mapping.

Ford MM, Camp JV, Geiger TM, Hopkins MB, Muldoon RL, Prestwich A, LaNeve DC, Hawkins AT.

Dis Colon Rectum. 2019 Jul;62(7):840-848. doi: 10.1097/DCR.0000000000001398.

PMID:
31188185
17.

Surgical management of primary colonic lymphoma: Big data for a rare problem.

Maguire LH, Geiger TM, Hardiman KM, Regenbogen SE, Hopkins MB, Muldoon RL, Ford MM, Hawkins AT.

J Surg Oncol. 2019 Sep;120(3):431-437. doi: 10.1002/jso.25582. Epub 2019 Jun 11.

PMID:
31187517
18.

Correction to: Progression of anal intraepithelial neoplasia in HIV-positive individuals: predisposing factors.

McCutcheon T, Hawkins AT, Muldoon RL, Hopkins MB, Geiger TM, Ford MM.

Tech Coloproctol. 2019 Jun;23(6):611. doi: 10.1007/s10151-019-02012-y.

PMID:
31168776
19.

Simultaneous Integration of Multi-omics Data Improves the Identification of Cancer Driver Modules.

Silverbush D, Cristea S, Yanovich-Arad G, Geiger T, Beerenwinkel N, Sharan R.

Cell Syst. 2019 May 22;8(5):456-466.e5. doi: 10.1016/j.cels.2019.04.005. Epub 2019 May 15.

PMID:
31103572
20.

American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Perioperative Opioid Minimization in Opioid-Naïve Patients.

Wu CL, King AB, Geiger TM, Grant MC, Grocott MPW, Gupta R, Hah JM, Miller TE, Shaw AD, Gan TJ, Thacker JKM, Mythen MG, McEvoy MD; Fourth Perioperative Quality Initiative Workgroup.

Anesth Analg. 2019 Aug;129(2):567-577. doi: 10.1213/ANE.0000000000004194.

PMID:
31082966
21.

Mitochondrial Regulation of the Hippocampal Firing Rate Set Point and Seizure Susceptibility.

Styr B, Gonen N, Zarhin D, Ruggiero A, Atsmon R, Gazit N, Braun G, Frere S, Vertkin I, Shapira I, Harel M, Heim LR, Katsenelson M, Rechnitz O, Fadila S, Derdikman D, Rubinstein M, Geiger T, Ruppin E, Slutsky I.

Neuron. 2019 Jun 5;102(5):1009-1024.e8. doi: 10.1016/j.neuron.2019.03.045. Epub 2019 Apr 29.

22.

Patient Factors that Predict Completion Proctectomy in Crohn's Disease.

Kavalukas SL, Hawkins AT, Baucom RB, Muldoon RL, Hopkins MB, Geiger TM, Ford MM.

Am Surg. 2019 Apr 1;85(4):431-433. No abstract available.

PMID:
31043206
23.

A retrospective cohort study of PD-L1 prevalence, molecular associations and clinical outcomes in patients with NSCLC: Results from the European Thoracic Oncology Platform (ETOP) Lungscape Project.

Kerr KM, Thunnissen E, Dafni U, Finn SP, Bubendorf L, Soltermann A, Verbeken E, Biernat W, Warth A, Marchetti A, Speel EM, Pokharel S, Quinn AM, Monkhorst K, Navarro A, Madsen LB, Radonic T, Wilson J, De Luca G, Gray SG, Cheney R, Savic S, Martorell M, Muley T, Baas P, Meldgaard P, Blackhall F, Dingemans AM, Dziadziuszko R, Vansteenkiste J, Weder W, Polydoropoulou V, Geiger T, Kammler R, Peters S, Stahel R; Lungscape Consortium.

Lung Cancer. 2019 May;131:95-103. doi: 10.1016/j.lungcan.2019.03.012. Epub 2019 Mar 15.

PMID:
31027705
24.

Progression of anal intraepithelial neoplasia in HIV-positive individuals: predisposing factors.

McCutcheon T, Hawkins AT, Muldoon RL, Hopkins MB, Geiger TM, Ford MM.

Tech Coloproctol. 2019 Apr;23(4):325-332. doi: 10.1007/s10151-019-01951-w. Epub 2019 Apr 23. Erratum in: Tech Coloproctol. 2019 Jun 5;:.

PMID:
31016550
25.

Assessing Hereditary Colorectal Cancer Referral Patterns to a Tertiary Care Center: A Novel Approach Using Geographic Information System Mapping.

Ford MM, Camp JV, Geiger TM, Hopkins MB, Muldoon RL, Prestwich A, LaNeve DC, Hawkins AT.

Dis Colon Rectum. 2019 Apr 5. doi: 10.1097/DCR.0000000000001398. [Epub ahead of print]

PMID:
30964760
26.

Specific inhibition of splicing factor activity by decoy RNA oligonucleotides.

Denichenko P, Mogilevsky M, Cléry A, Welte T, Biran J, Shimshon O, Barnabas GD, Danan-Gotthold M, Kumar S, Yavin E, Levanon EY, Allain FH, Geiger T, Levkowitz G, Karni R.

Nat Commun. 2019 Apr 8;10(1):1590. doi: 10.1038/s41467-019-09523-0.

27.

The AAMC Standardized Video Interview: Reactions and Use by Residency Programs During the 2018 Application Cycle.

Gallahue FE, Hiller KM, Bird SB, Calderone Haas MR, Deiorio NM, Hern HG, Jarou ZJ, Pierce A, Geiger T, Fletcher L.

Acad Med. 2019 Oct;94(10):1506-1512. doi: 10.1097/ACM.0000000000002714.

PMID:
30893064
28.

Microvesicle Proteomic Profiling of Uterine Liquid Biopsy for Ovarian Cancer Early Detection.

Barnabas GD, Bahar-Shany K, Sapoznik S, Helpman L, Kadan Y, Beiner M, Weitzner O, Arbib N, Korach J, Perri T, Katz G, Blecher A, Brandt B, Friedman E, Stockheim D, Jakobson-Setton A, Eitan R, Armon S, Brand H, Zadok O, Aviel-Ronen S, Harel M, Geiger T, Levanon K.

Mol Cell Proteomics. 2019 May;18(5):865-875. doi: 10.1074/mcp.RA119.001362. Epub 2019 Feb 13.

PMID:
30760538
29.

Identification of nucleolar protein NOM1 as a novel nuclear IGF1R-interacting protein.

Solomon-Zemler R, Pozniak Y, Geiger T, Werner H.

Mol Genet Metab. 2019 Mar;126(3):259-265. doi: 10.1016/j.ymgme.2019.01.002. Epub 2019 Jan 4.

PMID:
30639046
30.

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors.

Jachimowicz RD, Beleggia F, Isensee J, Velpula BB, Goergens J, Bustos MA, Doll MA, Shenoy A, Checa-Rodriguez C, Wiederstein JL, Baranes-Bachar K, Bartenhagen C, Hertwig F, Teper N, Nishi T, Schmitt A, Distelmaier F, Lüdecke HJ, Albrecht B, Krüger M, Schumacher B, Geiger T, Hoon DSB, Huertas P, Fischer M, Hucho T, Peifer M, Ziv Y, Reinhardt HC, Wieczorek D, Shiloh Y.

Cell. 2019 Jan 24;176(3):505-519.e22. doi: 10.1016/j.cell.2018.11.024. Epub 2019 Jan 3.

PMID:
30612738
31.

Diels-Alder adduct formation at solid interfaces between fullerenes and acenes.

Breuer T, Geiger T, Bettinger HF, Witte G.

J Phys Condens Matter. 2019 Jan 23;31(3):034003. doi: 10.1088/1361-648X/aaf01b.

PMID:
30524049
32.

Modulation of PI3K signaling to improve CAR T cell function.

Zheng W, Jones LL, Geiger TL.

Oncotarget. 2018 Nov 9;9(88):35807-35808. doi: 10.18632/oncotarget.26334. eCollection 2018 Nov 9. No abstract available.

33.

Ketorolac Use and Anastomotic Leak in Elective Colorectal Surgery: A Detailed Analysis.

Hawkins AT, McEvoy MD, Wanderer JP, Ford MM, Hopkins MB, Muldoon RL, Martin BJ, King AB, Geiger TM.

Dis Colon Rectum. 2018 Dec;61(12):1426-1434. doi: 10.1097/DCR.0000000000001244.

PMID:
30371548
34.

An enhanced recovery program in colorectal surgery is associated with decreased organ level rates of complications: a difference-in-differences analysis.

Hawkins AT, Geiger TM, King AB, Wanderer JP, Tiwari V, Muldoon RL, Ford MM, Dmochowski RR, Sandberg WS, Martin B, Hopkins MB, McEvoy MD.

Surg Endosc. 2019 Jul;33(7):2222-2230. doi: 10.1007/s00464-018-6508-2. Epub 2018 Oct 17.

PMID:
30334161
35.

IL-6 Promotes T Cell Proliferation and Expansion under Inflammatory Conditions in Association with Low-Level RORγt Expression.

Li B, Jones LL, Geiger TL.

J Immunol. 2018 Nov 15;201(10):2934-2946. doi: 10.4049/jimmunol.1800016. Epub 2018 Oct 12.

36.

Peptidoglycan editing by a specific LD-transpeptidase controls the muramidase-dependent secretion of typhoid toxin.

Geiger T, Pazos M, Lara-Tejero M, Vollmer W, Galán JE.

Nat Microbiol. 2018 Nov;3(11):1243-1254. doi: 10.1038/s41564-018-0248-x. Epub 2018 Sep 24.

PMID:
30250245
37.

Computer-Based Intensity Measurement Assists Pathologists in Scoring Phosphatase and Tensin Homolog Immunohistochemistry - Clinical Associations in NSCLC Patients of the European Thoracic Oncology Platform Lungscape Cohort.

Rulle U, Tsourti Z, Casanova R, Deml KF, Verbeken E, Thunnissen E, Warth A, Cheney R, Sejda A, Speel EJ, Madsen LB, Nonaka D, Navarro A, Sansano I, Marchetti A, Finn SP, Monkhorst K, Kerr KM, Haberecker M, Wu C, Zygoura P, Kammler R, Geiger T, Gendreau S, Schulze K, Vrugt B, Wild P, Moch H, Weder W, Ciftlik AT, Dafni U, Peters S, Bubendorf L, Stahel RA, Soltermann A.

J Thorac Oncol. 2018 Dec;13(12):1851-1863. doi: 10.1016/j.jtho.2018.08.2034. Epub 2018 Sep 18.

38.

Cell shape alteration during adipogenesis is associated with coordinated matrix cues.

Mor-Yossef Moldovan L, Lustig M, Naftaly A, Mardamshina M, Geiger T, Gefen A, Benayahu D.

J Cell Physiol. 2019 Apr;234(4):3850-3863. doi: 10.1002/jcp.27157. Epub 2018 Sep 7.

PMID:
30191963
39.

Use of the American College of Surgeons National Surgical Quality Improvement Program Surgical Risk Calculator During Preoperative Risk Discussion: The Patient Perspective.

Raymond BL, Wanderer JP, Hawkins AT, Geiger TM, Ehrenfeld JM, Stokes JW, McEvoy MD.

Anesth Analg. 2019 Apr;128(4):643-650. doi: 10.1213/ANE.0000000000003718.

PMID:
30169413
40.

Clinical Proteomics of Breast Cancer Reveals a Novel Layer of Breast Cancer Classification.

Yanovich G, Agmon H, Harel M, Sonnenblick A, Peretz T, Geiger T.

Cancer Res. 2018 Oct 15;78(20):6001-6010. doi: 10.1158/0008-5472.CAN-18-1079. Epub 2018 Aug 28.

41.

Principles of Systems Biology, No. 31.

Cho H, Berger B, Peng J, Galitzine C, Vitek O, Beltran PMJ, Cristea IM, Görtler F, Solbrig S, Wettig T, Oefner PJ, Spang R, Altenbuchinger M, Basso RS, Hochbaum D, Vandin F, Silverbush D, Cristea S, Yanovich G, Geiger T, Beerenwinkel N, Sharan R, Zhou Z, Luhmann N, Alikhan NF, Achtman M.

Cell Syst. 2018 Aug 22;7(2):133-135. doi: 10.1016/j.cels.2018.08.005.

42.

The Proteome of Prostate Cancer Bone Metastasis Reveals Heterogeneity with Prognostic Implications.

Iglesias-Gato D, Thysell E, Tyanova S, Crnalic S, Santos A, Lima TS, Geiger T, Cox J, Widmark A, Bergh A, Mann M, Flores-Morales A, Wikström P.

Clin Cancer Res. 2018 Nov 1;24(21):5433-5444. doi: 10.1158/1078-0432.CCR-18-1229. Epub 2018 Jul 24.

43.

Resection for anal melanoma: Is there an optimal approach?

Ford MM, Kauffmann RM, Geiger TM, Hopkins MB, Muldoon RL, Hawkins AT.

Surgery. 2018 Sep;164(3):466-472. doi: 10.1016/j.surg.2018.05.026. Epub 2018 Jul 2.

PMID:
30041967
44.

Neoadjuvant radiation for clinical T4 colon cancer: A potential improvement to overall survival.

Hawkins AT, Ford MM, Geiger TM, Hopkins MB, Kachnic LA, Muldoon RL, Glasgow SC.

Surgery. 2019 Feb;165(2):469-475. doi: 10.1016/j.surg.2018.06.015. Epub 2018 Jul 14.

PMID:
30017250
45.

Regulation of the opposing (p)ppGpp synthetase and hydrolase activities in a bifunctional RelA/SpoT homologue from Staphylococcus aureus.

Gratani FL, Horvatek P, Geiger T, Borisova M, Mayer C, Grin I, Wagner S, Steinchen W, Bange G, Velic A, Maček B, Wolz C.

PLoS Genet. 2018 Jul 9;14(7):e1007514. doi: 10.1371/journal.pgen.1007514. eCollection 2018 Jul.

46.

Haploidentical Donor Transplantation Using a Novel Clofarabine-containing Conditioning Regimen for Very High-risk Hematologic Malignant Neoplasms.

Sharma A, Kang G, Sunkara A, Inaba H, Jeha S, Cross SJ, Geiger T, Triplett B.

J Pediatr Hematol Oncol. 2018 Nov;40(8):e479-e485. doi: 10.1097/MPH.0000000000001222.

47.

Colorectal Cancer Screening and Diagnosis: A Patient-Centered Approach to Understanding Avoidance.

Geiger TM.

Dis Colon Rectum. 2018 Apr;61(4):417-418. doi: 10.1097/DCR.0000000000000968. No abstract available.

PMID:
29521819
48.

Bridging the Gap between Pentacene and Perfluoropentacene: Synthesis and Characterization of 2,3,9,10-Tetrafluoropentacene in the Neutral, Cationic, and Dicationic States.

Shen B, Geiger T, Einholz R, Reicherter F, Schundelmeier S, Maichle-Mössmer C, Speiser B, Bettinger HF.

J Org Chem. 2018 Mar 16;83(6):3149-3158. doi: 10.1021/acs.joc.7b03241. Epub 2018 Feb 27.

PMID:
29485868
49.

PI3K orchestration of the in vivo persistence of chimeric antigen receptor-modified T cells.

Zheng W, O'Hear CE, Alli R, Basham JH, Abdelsamed HA, Palmer LE, Jones LL, Youngblood B, Geiger TL.

Leukemia. 2018 May;32(5):1157-1167. doi: 10.1038/s41375-017-0008-6. Epub 2018 Feb 2.

50.

How good are we at selecting students that meet our mission? Outcomes of the 2011 and 2012 entering classes selected by a locally developed multiple mini interview.

Terregino CA, Copeland HL, Laumbach SG, Mehan D, Dunleavy D, Geiger T.

Med Teach. 2018 Dec;40(12):1300-1305. doi: 10.1080/0142159X.2018.1436165. Epub 2018 Feb 19.

PMID:
29457915

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