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Items: 42


BRD4 directs hematopoietic stem cell development and modulates macrophage inflammatory responses.

Dey A, Yang W, Gegonne A, Nishiyama A, Pan R, Yagi R, Grinberg A, Finkelman FD, Pfeifer K, Zhu J, Singer D, Zhu J, Ozato K.

EMBO J. 2019 Apr 1;38(7). pii: e100293. doi: 10.15252/embj.2018100293. Epub 2019 Mar 6.


Immature CD8 Single-Positive Thymocytes Are a Molecularly Distinct Subpopulation, Selectively Dependent on BRD4 for Their Differentiation.

Gegonne A, Chen QR, Dey A, Etzensperger R, Tai X, Singer A, Meerzaman D, Ozato K, Singer DS.

Cell Rep. 2018 Jul 3;24(1):117-129. doi: 10.1016/j.celrep.2018.06.007.


Erratum: BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin.

Devaiah BN, Case-Borden C, Gegonne A, Hsu CH, Chen Q, Meerzaman D, Dey A, Ozato K, Singer DS.

Nat Struct Mol Biol. 2017 Feb 6;24(2):194. doi: 10.1038/nsmb0217-194c. No abstract available.


Bromodomain 4: a cellular Swiss army knife.

Devaiah BN, Gegonne A, Singer DS.

J Leukoc Biol. 2016 Oct;100(4):679-686. Epub 2016 Jul 22. Review.


BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin.

Devaiah BN, Case-Borden C, Gegonne A, Hsu CH, Chen Q, Meerzaman D, Dey A, Ozato K, Singer DS.

Nat Struct Mol Biol. 2016 Jun;23(6):540-8. doi: 10.1038/nsmb.3228. Epub 2016 May 9. Erratum in: Nat Struct Mol Biol. 2017 Feb 6;24(2):194.


TAF7: traffic controller in transcription initiation.

Gegonne A, Devaiah BN, Singer DS.

Transcription. 2013 Jan-Feb;4(1):29-33. doi: 10.4161/trns.22842. Review.


The general transcription factor TAF7 is essential for embryonic development but not essential for the survival or differentiation of mature T cells.

Gegonne A, Tai X, Zhang J, Wu G, Zhu J, Yoshimoto A, Hanson J, Cultraro C, Chen QR, Guinter T, Yang Z, Hathcock K, Singer A, Rodriguez-Canales J, Tessarollo L, Mackem S, Meerzaman D, Buetow K, Singer DS.

Mol Cell Biol. 2012 May;32(10):1984-97. doi: 10.1128/MCB.06305-11. Epub 2012 Mar 12.


Novel functions for TAF7, a regulator of TAF1-independent transcription.

Devaiah BN, Lu H, Gegonne A, Sercan Z, Zhang H, Clifford RJ, Lee MP, Singer DS.

J Biol Chem. 2010 Dec 10;285(50):38772-80. doi: 10.1074/jbc.M110.173864. Epub 2010 Oct 11.


Histone modifications, but not nucleosomal positioning, correlate with major histocompatibility complex class I promoter activity in different tissues in vivo.

Kotekar AS, Weissman JD, Gegonne A, Cohen H, Singer DS.

Mol Cell Biol. 2008 Dec;28(24):7323-36. doi: 10.1128/MCB.00889-08. Epub 2008 Sep 22.


TFIID component TAF7 functionally interacts with both TFIIH and P-TEFb.

Gegonne A, Weissman JD, Lu H, Zhou M, Dasgupta A, Ribble R, Brady JN, Singer DS.

Proc Natl Acad Sci U S A. 2008 Apr 8;105(14):5367-72. doi: 10.1073/pnas.0801637105. Epub 2008 Apr 7.


TAF7: a possible transcription initiation check-point regulator.

Gegonne A, Weissman JD, Zhou M, Brady JN, Singer DS.

Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):602-7. Epub 2006 Jan 9.


A T lymphocyte-specific transcription complex containing RUNX1 activates MHC class I expression.

Howcroft TK, Weissman JD, Gegonne A, Singer DS.

J Immunol. 2005 Feb 15;174(4):2106-15.


Distinct transcriptional pathways regulate basal and activated major histocompatibility complex class I expression.

Howcroft TK, Raval A, Weissman JD, Gegonne A, Singer DS.

Mol Cell Biol. 2003 May;23(10):3377-91.


TAFII55 binding to TAFII250 inhibits its acetyltransferase activity.

Gegonne A, Weissman JD, Singer DS.

Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12432-7. Epub 2001 Oct 9.


Determinants of vitellogenin B1 promoter architecture. HNF3 and estrogen responsive transcription within chromatin.

Robyr D, Gegonne A, Wolffe AP, Wahli W.

J Biol Chem. 2000 Sep 8;275(36):28291-300.


Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation.

Wade PA, Gegonne A, Jones PL, Ballestar E, Aubry F, Wolffe AP.

Nat Genet. 1999 Sep;23(1):62-6.


Cellular and viral trans-acting factors modulate N-myc2 promoter activity in woodchuck liver tumors.

Flajolet M, Gegonne A, Ghysdael J, Tiollais P, Buendia MA, Fourel G.

Oncogene. 1997 Aug 28;15(9):1103-10.


Synergistic activation of the HTLV1 LTR Ets-responsive region by transcription factors Ets1 and Sp1.

Gégonne A, Bosselut R, Bailly RA, Ghysdael J.

EMBO J. 1993 Mar;12(3):1169-78.


A phorbol ester response element within the human T-cell receptor beta-chain enhancer.

Prosser HM, Wotton D, Gegonne A, Ghysdael J, Wang S, Speck NA, Owen MJ.

Proc Natl Acad Sci U S A. 1992 Oct 15;89(20):9934-8.


Analysis of the DNA binding and transcriptional activation properties of the Ets1 oncoprotein.

Gegonne A, Punyammalee B, Rabault B, Bosselut R, Seneca S, Crabeel M, Ghysdael J.

New Biol. 1992 May;4(5):512-9.


Sequence-specific interaction of the Ets1 protein with the long terminal repeat of the human T-lymphotropic virus type I.

Gitlin SD, Bosselut R, Gégonne A, Ghysdael J, Brady JN.

J Virol. 1991 Oct;65(10):5513-23.


Expression of ETS proto-oncogenes in astrocytes in human cortex.

Amouyel P, Gégonne A, Delacourte A, Défossez A, Stéhelin D.

Brain Res. 1988 Apr 26;447(1):149-53.


The c-ets-1 proto-oncogene is rearranged in some cases of acute lymphoblastic leukaemia.

Goyns MH, Hann IM, Stewart J, Gegonne A, Birnie GD.

Br J Cancer. 1987 Nov;56(5):611-3. No abstract available.


The bovine leukemia virus p34 is a transactivator protein.

Willems L, Gegonne A, Chen G, Burny A, Kettmann R, Ghysdael J.

EMBO J. 1987 Nov;6(11):3385-9.


Maternal origin of a de novo balanced t(21q21q) identified by ets-2 polymorphism.

Créau-Goldberg N, Gegonne A, Delabar J, Cochet C, Cabanis MO, Stehelin D, Turleau C, de Grouchy J.

Hum Genet. 1987 Aug;76(4):396-8.


Submicroscopic duplication of chromosome 21 and trisomy 21 phenotype (Down syndrome).

Delabar JM, Sinet PM, Chadefaux B, Nicole A, Gegonne A, Stehelin D, Fridlansky F, Créau-Goldberg N, Turleau C, de Grouchy J.

Hum Genet. 1987 Jul;76(3):225-9.


Multiple domains for the chicken cellular sequences homologous to the v-ets oncogene of the E26 retrovirus.

Gegonne A, Leprince D, Duterque-Coquillaud M, Vandenbunder B, Flourens A, Ghysdael J, Debuire B, Stehelin D.

Mol Cell Biol. 1987 Feb;7(2):806-12.


The 5' extremity of the v-ets oncogene of avian leukemia virus E26 encodes amino acid sequences not derived from the major c-ets-encoded cellular proteins.

Gegonne A, Leprince D, Pognonec P, Dernis D, Raes MB, Stehelin D, Ghysdael J.

Virology. 1987 Jan;156(1):177-80.


Identification in chicken macrophages of a set of proteins related to, but distinct from, the chicken cellular c-ets-encoded protein p54c-ets.

Ghysdael J, Gegonne A, Pognonec P, Boulukos K, Leprince D, Dernis D, Lagrou C, Stehelin D.

EMBO J. 1986 Sep;5(9):2251-6.


Comparison of constitutional and tumor-associated 11;22 translocations: nonidentical breakpoints on chromosomes 11 and 22.

Griffin CA, McKeon C, Israel MA, Gegonne A, Ghysdael J, Stehelin D, Douglass EC, Green AE, Emanuel BS.

Proc Natl Acad Sci U S A. 1986 Aug;83(16):6122-6.


Identification and preferential expression in thymic and bursal lymphocytes of a c-ets oncogene-encoded Mr 54,000 cytoplasmic protein.

Ghysdael J, Gegonne A, Pognonec P, Dernis D, Leprince D, Stehelin D.

Proc Natl Acad Sci U S A. 1986 Mar;83(6):1714-8.


Rearrangement of chromosome 21 in Alzheimer's disease.

Delabar JM, Lamour Y, Gegonne A, Davous P, Roudier M, Nicole A, Ceballos I, Amouyel P, Stehelin D, Sinet PM.

Ann Genet. 1986;29(4):226-8.


[Abnormal localization of proto-oncogene c-ets 1 in acute leukemia with translocation t(1: 11)(q21: q23)].

Caubet JF, Gegonne A, Stéhelin D, Berger R.

C R Acad Sci III. 1986;302(16):589-91. French.


[Preparation and characterization of antisera specific to various polypeptide domains corresponding to the v-ets oncogene of the avian leukemia virus E26].

Gegonne A, Pognonec P, Leprince D, Dernis D, Remaut E, Stehelin D, Ghysdael J.

C R Acad Sci III. 1986;303(7):253-6. French.


Increased transcription of the c-myc oncogene in two methylcholanthrene-induced quail fibroblastic cell lines.

Saule S, Martin P, Gegonne A, Begue A, Lagrou C, Stehelin D.

Exp Cell Res. 1984 Dec;155(2):496-506.


Chromosomal localization of the human proto-oncogene c-ets.

de Taisne C, Gegonne A, Stehelin D, Bernheim A, Berger R.

Nature. 1984 Aug 16-22;310(5978):581-3.


A putative second cell-derived oncogene of the avian leukaemia retrovirus E26.

Leprince D, Gegonne A, Coll J, de Taisne C, Schneeberger A, Lagrou C, Stehelin D.

Nature. 1983 Nov 24-30;306(5941):395-7.


The human DNA locus related to the oncogene myb of avian myeloblastosis virus (AMV): molecular cloning and structural characterization.

Leprince D, Saule S, de Taisne C, Gegonne A, Begue A, Righi M, Stehelin D.

EMBO J. 1983;2(7):1073-8.

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