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Items: 1 to 50 of 266

1.

Overexpression of kynurenic acid and 3-hydroxyanthranilic acid after rat traumatic brain injury.

Mangas A, Heredia M, Riolobos A, De la Fuente A, Criado JM, Yajeya J, Geffard M, Coveñas R.

Eur J Histochem. 2018 Nov 14;62(4). doi: 10.4081/ejh.2018.2985.

2.

Towards a new classification of stable phase schizophrenia into major and simple neuro-cognitive psychosis: Results of unsupervised machine learning analysis.

Kanchanatawan B, Sriswasdi S, Thika S, Stoyanov D, Sirivichayakul S, Carvalho AF, Geffard M, Maes M.

J Eval Clin Pract. 2018 Aug;24(4):879-891. doi: 10.1111/jep.12945. Epub 2018 May 23.

PMID:
29790237
3.

GEMALS: A promising therapy for amyotrophic lateral sclerosis.

Geffard M, Mangas A, Bedat D, Coveñas R.

Exp Ther Med. 2018 Apr;15(4):3203-3210. doi: 10.3892/etm.2018.5868. Epub 2018 Feb 14.

4.

Deficit schizophrenia is a discrete diagnostic category defined by neuro-immune and neurocognitive features: results of supervised machine learning.

Kanchanatawan B, Sriswasdi S, Thika S, Sirivichayakul S, Carvalho AF, Geffard M, Kubera M, Maes M.

Metab Brain Dis. 2018 Aug;33(4):1053-1067. doi: 10.1007/s11011-018-0208-4. Epub 2018 Mar 11.

PMID:
29527624
5.
6.

Generation of specific antisera directed against D-amino acids: focus on the neuroanatomical distribution of D-glutamate and other D-amino acids.

Coveñas R, Mangas A, Sánchez ML, Cadena D, Husson M, Geffard M.

Folia Histochem Cytobiol. 2017;55(4):177-189. doi: 10.5603/FHC.a2017.0023. Epub 2018 Jan 24. Review.

PMID:
29363733
7.

Natural regulatory IgM-mediated autoimmune responses directed against malondialdehyde regulate oxidative and nitrosative pathways and coupled with IgM responses to nitroso adducts attenuate depressive and physiosomatic symptoms at the end of term pregnancy.

Roomruangwong C, Barbosa DS, de Farias CC, Matsumoto AK, Baltus THL, Morelli NR, Kanchanatawan B, Duleu S, Geffard M, Maes M.

Psychiatry Clin Neurosci. 2018 Feb;72(2):116-130. doi: 10.1111/pcn.12625. Epub 2018 Jan 5.

8.

Changes in Tryptophan Catabolite (TRYCAT) Pathway Patterning Are Associated with Mild Impairments in Declarative Memory in Schizophrenia and Deficits in Semantic and Episodic Memory Coupled with Increased False-Memory Creation in Deficit Schizophrenia.

Kanchanatawan B, Hemrungrojn S, Thika S, Sirivichayakul S, Ruxrungtham K, Carvalho AF, Geffard M, Anderson G, Maes M.

Mol Neurobiol. 2018 Jun;55(6):5184-5201. doi: 10.1007/s12035-017-0751-8. Epub 2017 Sep 5.

PMID:
28875464
9.

Gemst: a taylor-made combination that reverts neuroanatomical changes in stroke.

Mangas A, Yajeya J, González N, Ruiz I, Pernìa M, Geffard M, Coveñas R.

Eur J Histochem. 2017 May 25;61(2):2790. doi: 10.4081/ejh.2017.2790.

10.

Activated neuro-oxidative and neuro-nitrosative pathways at the end of term are associated with inflammation and physio-somatic and depression symptoms, while predicting outcome characteristics in mother and baby.

Roomruangwong C, Barbosa DS, Matsumoto AK, Nogueira AS, Kanchanatawan B, Sirivichayakul S, Carvalho AF, Duleu S, Geffard M, Moreira EG, Maes M.

J Affect Disord. 2017 Dec 1;223:49-58. doi: 10.1016/j.jad.2017.07.002. Epub 2017 Jul 6.

PMID:
28719808
11.

IgM-mediated autoimmune responses to oxidative specific epitopes, but not nitrosylated adducts, are significantly decreased in pregnancy: association with bacterial translocation, perinatal and lifetime major depression and the tryptophan catabolite (TRYCAT) pathway.

Roomruangwong C, Kanchanatawan B, Sirivichayakul S, Anderson G, Carvalho AF, Duleu S, Geffard M, Maes M.

Metab Brain Dis. 2017 Oct;32(5):1571-1583. doi: 10.1007/s11011-017-0040-2. Epub 2017 Jun 9.

PMID:
28600633
12.

Follow-up of multiple sclerosis patients treated with Endotherapia (GEMSP).

Geffard M, Mangas A, Coveñas R.

Biomed Rep. 2017 Mar;6(3):307-313. doi: 10.3892/br.2017.857. Epub 2017 Feb 9.

13.

IgA/IgM Responses to Gram-Negative Bacteria are not Associated with Perinatal Depression, but with Physio-Somatic Symptoms and Activation of the Tryptophan Catabolite Pathway at the End of Term and Postnatal Anxiety.

Roomruangwong C, Kanchanatawan B, Sirivichayakul S, Anderson G, Carvalho AF, Duleu S, Geffard M, Maes M.

CNS Neurol Disord Drug Targets. 2017 Apr 7. doi: 10.2174/1871527316666170407145533. [Epub ahead of print]

PMID:
28403801
14.

Deficit Schizophrenia Is Characterized by Defects in IgM-Mediated Responses to Tryptophan Catabolites (TRYCATs): a Paradigm Shift Towards Defects in Natural Self-Regulatory Immune Responses Coupled with Mucosa-Derived TRYCAT Pathway Activation.

Kanchanatawan B, Sirivichayakul S, Ruxrungtham K, Carvalho AF, Geffard M, Anderson G, Maes M.

Mol Neurobiol. 2018 Mar;55(3):2214-2226. doi: 10.1007/s12035-017-0465-y. Epub 2017 Mar 14.

PMID:
28290151
15.

Physio-somatic symptoms in schizophrenia: association with depression, anxiety, neurocognitive deficits and the tryptophan catabolite pathway.

Kanchanatawan B, Sirivichayakul S, Thika S, Ruxrungtham K, Carvalho AF, Geffard M, Anderson G, Noto C, Ivanova R, Maes M.

Metab Brain Dis. 2017 Aug;32(4):1003-1016. doi: 10.1007/s11011-017-9982-7. Epub 2017 Mar 3.

PMID:
28258445
16.

Deficit, but Not Nondeficit, Schizophrenia Is Characterized by Mucosa-Associated Activation of the Tryptophan Catabolite (TRYCAT) Pathway with Highly Specific Increases in IgA Responses Directed to Picolinic, Xanthurenic, and Quinolinic Acid.

Kanchanatawan B, Sirivichayakul S, Ruxrungtham K, Carvalho AF, Geffard M, Ormstad H, Anderson G, Maes M.

Mol Neurobiol. 2018 Feb;55(2):1524-1536. doi: 10.1007/s12035-017-0417-6. Epub 2017 Feb 8.

PMID:
28181189
17.

Overexpression of kynurenic acid in stroke: An endogenous neuroprotector?

Mangas A, Yajeya J, González N, Ruiz I, Duleu S, Geffard M, Coveñas R.

Ann Anat. 2017 May;211:33-38. doi: 10.1016/j.aanat.2017.01.002. Epub 2017 Feb 3.

PMID:
28163204
18.

3-hydroxi-anthranilic acid is early expressed in stroke.

Mangas A, Yajeya J, González N, Ruiz I, Geffard M, Coveñas R.

Eur J Histochem. 2016 Dec 2;60(4):2709. doi: 10.4081/ejh.2016.2709.

19.

Detection of pantothenic acid-immunoreactive neurons in the rat lateral septal nucleus by a newly developed antibody.

Mangas A, Yajeya J, Gonzalez N, Husson M, Geffard M, Coveñas R.

Folia Histochem Cytobiol. 2016;54(4):186-192. doi: 10.5603/FHC.a2016.0024. Epub 2016 Dec 14.

20.

NO-tryptophan: a new small molecule located in the rat brain.

Mangas A, Yajeya J, González N, Duleu S, Geffard M, Coveñas R.

Eur J Histochem. 2016 Sep 22;60(3):2692. doi: 10.4081/ejh.2016.2692.

21.

Body image dissatisfaction in pregnant and non-pregnant females is strongly predicted by immune activation and mucosa-derived activation of the tryptophan catabolite (TRYCAT) pathway.

Roomruangwong C, Kanchanatawan B, Carvalho AF, Sirivichayakul S, Duleu S, Geffard M, Maes M.

World J Biol Psychiatry. 2018 Apr;19(3):200-209. doi: 10.1080/15622975.2016.1213881. Epub 2016 Aug 30.

PMID:
27427239
22.

IgA/IgM responses to tryptophan and tryptophan catabolites (TRYCATs) are differently associated with prenatal depression, physio-somatic symptoms at the end of term and premenstrual syndrome.

Roomruangwong C, Kanchanatawan B, Sirivichayakul S, Anderson G, Carvalho AF, Duleu S, Geffard M, Maes M.

Mol Neurobiol. 2017 May;54(4):3038-3049. doi: 10.1007/s12035-016-9877-3. Epub 2016 Apr 1.

PMID:
27037573
23.

Developmental study of vitamin C distribution in children's brainstems by immunohistochemistry.

Coveñas R, González-Fuentes J, Rivas-Infante E, Lagartos-Donate MJ, Mangas A, Geffard M, Arroyo-Jiménez MM, Cebada-Sánchez S, Insausti R, Marcos P.

Ann Anat. 2015 Sep;201:65-78. doi: 10.1016/j.aanat.2015.06.001. Epub 2015 Jul 6.

PMID:
26226232
24.
25.

Aryl hydrocarbon receptor control of a disease tolerance defence pathway.

Bessede A, Gargaro M, Pallotta MT, Matino D, Servillo G, Brunacci C, Bicciato S, Mazza EM, Macchiarulo A, Vacca C, Iannitti R, Tissi L, Volpi C, Belladonna ML, Orabona C, Bianchi R, Lanz TV, Platten M, Della Fazia MA, Piobbico D, Zelante T, Funakoshi H, Nakamura T, Gilot D, Denison MS, Guillemin GJ, DuHadaway JB, Prendergast GC, Metz R, Geffard M, Boon L, Pirro M, Iorio A, Veyret B, Romani L, Grohmann U, Fallarino F, Puccetti P.

Nature. 2014 Jul 10;511(7508):184-90. doi: 10.1038/nature13323.

26.

Lauryl-poly-L-lysine: A New Antimicrobial Agent?

Vidal L, Thuault V, Mangas A, Coveñas R, Thienpont A, Geffard M.

J Amino Acids. 2014;2014:672367. doi: 10.1155/2014/672367. Epub 2014 Feb 23.

27.

GEMSP exerts a myelin-protecting role in the rat optic nerve.

Mangas A, Vecino E, David Rodríguez F, Geffard M, Coveñas R.

Neurol Res. 2013 Nov;35(9):903-11. doi: 10.1179/1743132813Y.0000000233. Epub 2013 Jun 20.

PMID:
23816275
28.

In myalgic encephalomyelitis/chronic fatigue syndrome, increased autoimmune activity against 5-HT is associated with immuno-inflammatory pathways and bacterial translocation.

Maes M, Ringel K, Kubera M, Anderson G, Morris G, Galecki P, Geffard M.

J Affect Disord. 2013 Sep 5;150(2):223-30. doi: 10.1016/j.jad.2013.03.029. Epub 2013 May 10.

PMID:
23664637
29.

In depression, bacterial translocation may drive inflammatory responses, oxidative and nitrosative stress (O&NS), and autoimmune responses directed against O&NS-damaged neoepitopes.

Maes M, Kubera M, Leunis JC, Berk M, Geffard M, Bosmans E.

Acta Psychiatr Scand. 2013 May;127(5):344-54. doi: 10.1111/j.1600-0447.2012.01908.x. Epub 2012 Aug 17.

PMID:
22900942
30.

Increased autoimmune responses against auto-epitopes modified by oxidative and nitrosative damage in depression: implications for the pathways to chronic depression and neuroprogression.

Maes M, Kubera M, Mihaylova I, Geffard M, Galecki P, Leunis JC, Berk M.

J Affect Disord. 2013 Jul;149(1-3):23-9. doi: 10.1016/j.jad.2012.06.039. Epub 2012 Aug 13.

PMID:
22898471
31.

IgM-mediated autoimmune responses directed against anchorage epitopes are greater in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) than in major depression.

Maes M, Mihaylova I, Kubera M, Leunis JC, Twisk FN, Geffard M.

Metab Brain Dis. 2012 Dec;27(4):415-23. doi: 10.1007/s11011-012-9316-8. Epub 2012 May 22.

PMID:
22614823
32.

GEMSP: a new therapeutic approach to multiple sclerosis.

Geffard M, Duleu S, Bessede A, Vigier V, Bodet D, Mangas A, Covenas R.

Cent Nerv Syst Agents Med Chem. 2012 Sep;12(3):173-81. Review.

PMID:
22533511
33.

Direct visualization of retinoic acid in the rat hypothalamus: an immunohistochemical study.

Mangas A, Bodet D, Duleu S, Yajeya J, Geffard M, Coveñas R.

Neurosci Lett. 2012 Feb 10;509(1):64-8. doi: 10.1016/j.neulet.2011.12.053. Epub 2012 Jan 3.

PMID:
22230896
34.

In utero and early-life exposure of rats to a Wi-Fi signal: screening of immune markers in sera and gestational outcome.

Aït-Aïssa S, Billaudel B, Poulletier de Gannes F, Ruffié G, Duleu S, Hurtier A, Haro E, Taxile M, Athané A, Geffard M, Wu T, Wiart J, Bodet D, Veyret B, Lagroye I.

Bioelectromagnetics. 2012 Jul;33(5):410-20. doi: 10.1002/bem.21699. Epub 2012 Jan 6.

PMID:
22228576
35.

Increased IgA responses to the LPS of commensal bacteria is associated with inflammation and activation of cell-mediated immunity in chronic fatigue syndrome.

Maes M, Twisk FN, Kubera M, Ringel K, Leunis JC, Geffard M.

J Affect Disord. 2012 Feb;136(3):909-17. doi: 10.1016/j.jad.2011.09.010. Epub 2011 Oct 2.

PMID:
21967891
36.

IgM-mediated autoimmune responses directed against multiple neoepitopes in depression: new pathways that underpin the inflammatory and neuroprogressive pathophysiology.

Maes M, Mihaylova I, Kubera M, Leunis JC, Geffard M.

J Affect Disord. 2011 Dec;135(1-3):414-8. doi: 10.1016/j.jad.2011.08.023. Epub 2011 Sep 17.

PMID:
21930301
37.

Frontiers in vitamin research: new antibodies, new data.

Coveñas R, Mangas A, Bodet D, Duleu S, Marcos P, Karakas B, Geffard M.

ScientificWorldJournal. 2011 Jun 9;11:1226-42. doi: 10.1100/tsw.2011.115. Review.

38.

(Neuro)inflammation and neuroprogression as new pathways and drug targets in depression: from antioxidants to kinase inhibitors.

Maes M, Leonard B, Fernandez A, Kubera M, Nowak G, Veerhuis R, Gardner A, Ruckoanich P, Geffard M, Altamura C, Galecki P, Berk M.

Prog Neuropsychopharmacol Biol Psychiatry. 2011 Apr 29;35(3):659-63. doi: 10.1016/j.pnpbp.2011.02.019. Epub 2011 Mar 2. No abstract available.

PMID:
21376099
39.

Endotherapia: a new frontier in the treatment of multiple sclerosis and other chronic diseases.

Geffard M, de Bisschop L, Duleu S, Hassaine N, Mangas A, Coveñas R.

Discov Med. 2010 Nov;10(54):443-51.

40.

Circulating Antibodies to IDO/THO Pathway Metabolites in Alzheimer's Disease.

Duleu S, Mangas A, Sevin F, Veyret B, Bessede A, Geffard M.

Int J Alzheimers Dis. 2010 Mar 15;2010. pii: 501541. doi: 10.4061/2010/501541.

41.

New drug therapies for multiple sclerosis.

Mangas A, Coveñas R, Geffard M.

Curr Opin Neurol. 2010 Jun;23(3):287-92. doi: 10.1097/WCO.0b013e32833960f6. Review.

PMID:
20414110
42.

Amyotrophic lateral sclerosis (ALS) and extremely-low frequency (ELF) magnetic fields: a study in the SOD-1 transgenic mouse model.

Poulletier de Gannes F, Ruffié G, Taxile M, Ladevèze E, Hurtier A, Haro E, Duleu S, Charlet de Sauvage R, Billaudel B, Geffard M, Veyret B, Lagroye I.

Amyotroph Lateral Scler. 2009 Oct-Dec;10(5-6):370-3. doi: 10.3109/17482960802320396.

PMID:
19922126
43.

A confirmation study of Russian and Ukrainian data on effects of 2450 MHz microwave exposure on immunological processes and teratology in rats.

de Gannes FP, Taxile M, Duleu S, Hurtier A, Haro E, Geffard M, Ruffié G, Billaudel B, Lévêque P, Dufour P, Lagroye I, Veyret B.

Radiat Res. 2009 Nov;172(5):617-24. doi: 10.1667/RR1541.1.

PMID:
19883230
44.

Circulating antibodies directed against "polycyclic aromatic hydrocarbon-like" structures in the sera of cancer patients.

Pouns O, Mangas A, Coveñas R, Geffard M.

Cancer Epidemiol. 2009 Jul;33(1):3-8. doi: 10.1016/j.canep.2009.04.013. Epub 2009 May 15.

PMID:
19679040
45.

A new drug candidate (GEMSP) for multiple sclerosis.

Mangas A, Coveñas R, Bodet D, Duleu S, Geffard M.

Curr Med Chem. 2009;16(25):3203-14. Epub 2009 Sep 1. Review.

PMID:
19548873
46.

Vitamins in the monkey brain: An immunocytochemical study.

Mangas A, Coveñas R, Bodet D, Duleu S, Marcos P, Geffard M.

J Chem Neuroanat. 2009 Sep;38(1):1-8. doi: 10.1016/j.jchemneu.2009.05.007. Epub 2009 May 27.

PMID:
19477264
47.

Evaluation of the effects of a new drug candidate (GEMSP) in a chronic EAE model.

Mangas A, Coveñas R, Bodet D, de León M, Duleu S, Geffard M.

Int J Biol Sci. 2008 May 22;4(3):150-60.

48.

Gemals, a new drug candidate, extends lifespan and improves electromyographic parameters in a rat model of amyotrophic lateral sclerosis.

Nicaise C, Coupier J, Dabadie MP, De Decker R, Mangas A, Bodet D, Poncelet L, Geffard M, Pochet R.

Amyotroph Lateral Scler. 2008 Apr;9(2):85-90. doi: 10.1080/17482960701788180.

PMID:
18428000
49.

Localization of L-DOPA uptake and decarboxylating neuronal structures in the cat brain using dopamine immunohistochemistry.

Kitahama K, Geffard M, Araneda S, Arai R, Ogawa K, Nagatsu I, Pequignot JM.

Brain Res. 2007 Sep 5;1167:56-70. Epub 2007 Jul 17.

PMID:
17692830
50.

Targeted and persistent effects of NO mediated by S-nitrosation of tissue thiols in arteries with endothelial dysfunction.

Sarr M, Chataigneau M, Etienne-Selloum N, Diallo AS, Schott C, Geffard M, Stoclet JC, Schini-Kerth VB, Muller B.

Nitric Oxide. 2007 Aug;17(1):1-9. Epub 2007 Apr 25.

PMID:
17566772

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