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Items: 1 to 50 of 201

1.

Activated zinc transporter ZIP7 as an indicator of anti-hormone resistance in breast cancer.

Ziliotto S, Gee JMW, Ellis IO, Green AR, Finlay P, Gobbato A, Taylor KM.

Metallomics. 2019 Sep 1;11(9):1579-1592. doi: 10.1039/c9mt00136k. Epub 2019 Sep 4.

PMID:
31483418
2.

PAK4 regulates stemness and progression in endocrine resistant ER-positive metastatic breast cancer.

Santiago-Gómez A, Kedward T, Simões BM, Dragoni I, NicAmhlaoibh R, Trivier E, Sabin V, Gee JM, Sims AH, Howell SJ, Clarke RB.

Cancer Lett. 2019 Aug 28;458:66-75. doi: 10.1016/j.canlet.2019.05.014. Epub 2019 May 20.

3.

Assessing Behavioral Associations in a Hybrid Zone through Social Network Analysis: Complex Assortative Behaviors Structure Associations in a Hybrid Quail Population.

Zonana DM, Gee JM, Bridge ES, Breed MD, Doak DF.

Am Nat. 2019 Jun;193(6):852-865. doi: 10.1086/703158. Epub 2019 Apr 17.

PMID:
31094596
4.

MicroRNA-196a is regulated by ER and is a prognostic biomarker in ER+ breast cancer.

Milevskiy MJG, Gujral U, Del Lama Marques C, Stone A, Northwood K, Burke LJ, Gee JMW, Nephew K, Clark S, Brown MA.

Br J Cancer. 2019 Mar;120(6):621-632. doi: 10.1038/s41416-019-0395-8. Epub 2019 Feb 20.

5.

Correction to: Heregulin β1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells.

Hutcheson IR, Knowlden JM, Hiscox SE, Barrow D, Gee JMW, Robertson JF, Ellis IO, Nicholson RI.

Breast Cancer Res. 2018 Aug 30;20(1):98. doi: 10.1186/s13058-018-0999-6.

6.

Evaluation of Complications and Costs During Overlapping Transsphenoidal Surgery in the Treatment of Pituitary Adenoma.

Karsy M, Bowers CA, Scoville J, Kundu B, Azab MA, Gee JM, Guan J, Couldwell WT.

Neurosurgery. 2019 May 1;84(5):1104-1111. doi: 10.1093/neuros/nyy269. Erratum in: Neurosurgery. 2018 Oct 1;83(4):845.

PMID:
29897572
7.

Implementing a Multisite Clinical Trial in the Midst of an Ebola Outbreak: Lessons Learned From the Sierra Leone Trial to Introduce a Vaccine Against Ebola.

Carter RJ, Idriss A, Widdowson MA, Samai M, Schrag SJ, Legardy-Williams JK, Estivariz CF, Callis A, Carr W, Webber W, Fischer ME, Hadler S, Sahr F, Thompson M, Greby SM, Edem-Hotah J, Momoh RM, McDonald W, Gee JM, Kallon AF, Spencer-Walters D, Bresee JS, Cohn A, Hersey S, Gibson L, Schuchat A, Seward JF.

J Infect Dis. 2018 May 18;217(suppl_1):S16-S23. doi: 10.1093/infdis/jix657.

8.

Ruptured Persistent Trigeminal Artery Causing Direct Cavernous Sinus Fistula Treated with Pipeline Embolization and Minimal Coiling.

Yoon NK, Awad AW, Gee JM, Taussky P.

World Neurosurg. 2018 Jan;109:471-475.e1. doi: 10.1016/j.wneu.2017.10.017. Epub 2017 Oct 16.

PMID:
29042328
9.

Long-range regulators of the lncRNA HOTAIR enhance its prognostic potential in breast cancer.

Milevskiy MJ, Al-Ejeh F, Saunus JM, Northwood KS, Bailey PJ, Betts JA, McCart Reed AE, Nephew KP, Stone A, Gee JM, Dowhan DH, Dray E, Shewan AM, French JD, Edwards SL, Clark SJ, Lakhani SR, Brown MA.

Hum Mol Genet. 2016 Aug 1;25(15):3269-3283. doi: 10.1093/hmg/ddw177. Epub 2016 Jul 4.

10.

ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells.

Gallego-Ortega D, Ledger A, Roden DL, Law AM, Magenau A, Kikhtyak Z, Cho C, Allerdice SL, Lee HJ, Valdes-Mora F, Herrmann D, Salomon R, Young AI, Lee BY, Sergio CM, Kaplan W, Piggin C, Conway JR, Rabinovich B, Millar EK, Oakes SR, Chtanova T, Swarbrick A, Naylor MJ, O'Toole S, Green AR, Timpson P, Gee JM, Ellis IO, Clark SJ, Ormandy CJ.

PLoS Biol. 2015 Dec 30;13(12):e1002330. doi: 10.1371/journal.pbio.1002330. eCollection 2015 Dec.

11.

Knockdown of the small conductance Ca(2+) -activated K(+) channels is potently cytotoxic in breast cancer cell lines.

Abdulkareem ZA, Gee JM, Cox CD, Wann KT.

Br J Pharmacol. 2016 Jan;173(1):177-90. doi: 10.1111/bph.13357. Epub 2015 Dec 5.

12.

Altered structure and function of astrocytes following status epilepticus.

Wilcox KS, Gee JM, Gibbons MB, Tvrdik P, White JA.

Epilepsy Behav. 2015 Aug;49:17-9. doi: 10.1016/j.yebeh.2015.05.002. Epub 2015 Jul 26. Review.

13.

Biological effects of fulvestrant on estrogen receptor positive human breast cancer: short, medium and long-term effects based on sequential biopsies.

Agrawal A, Robertson JF, Cheung KL, Gutteridge E, Ellis IO, Nicholson RI, Gee JM.

Int J Cancer. 2016 Jan 1;138(1):146-59. doi: 10.1002/ijc.29682. Epub 2015 Jul 30.

14.

DNA methylation of oestrogen-regulated enhancers defines endocrine sensitivity in breast cancer.

Stone A, Zotenko E, Locke WJ, Korbie D, Millar EK, Pidsley R, Stirzaker C, Graham P, Trau M, Musgrove EA, Nicholson RI, Gee JM, Clark SJ.

Nat Commun. 2015 Jul 14;6:7758. doi: 10.1038/ncomms8758.

15.

Intracellular calcium dynamics in cortical microglia responding to focal laser injury in the PC::G5-tdT reporter mouse.

Pozner A, Xu B, Palumbos S, Gee JM, Tvrdik P, Capecchi MR.

Front Mol Neurosci. 2015 May 8;8:12. doi: 10.3389/fnmol.2015.00012. eCollection 2015.

16.

Imaging activity in astrocytes and neurons with genetically encoded calcium indicators following in utero electroporation.

Gee JM, Gibbons MB, Taheri M, Palumbos S, Morris SC, Smeal RM, Flynn KF, Economo MN, Cizek CG, Capecchi MR, Tvrdik P, Wilcox KS, White JA.

Front Mol Neurosci. 2015 Apr 15;8:10. doi: 10.3389/fnmol.2015.00010. eCollection 2015.

17.

A good drug made better: the fulvestrant dose-response story.

Robertson JF, Lindemann J, Garnett S, Anderson E, Nicholson RI, Kuter I, Gee JM.

Clin Breast Cancer. 2014 Dec;14(6):381-9. doi: 10.1016/j.clbc.2014.06.005. Epub 2014 Jun 24. Review.

PMID:
25457991
18.

Imaging activity in neurons and glia with a Polr2a-based and cre-dependent GCaMP5G-IRES-tdTomato reporter mouse.

Gee JM, Smith NA, Fernandez FR, Economo MN, Brunert D, Rothermel M, Morris SC, Talbot A, Palumbos S, Ichida JM, Shepherd JD, West PJ, Wachowiak M, Capecchi MR, Wilcox KS, White JA, Tvrdik P.

Neuron. 2014 Sep 3;83(5):1058-72. doi: 10.1016/j.neuron.2014.07.024. Epub 2014 Aug 21.

19.

Impact of dual mTORC1/2 mTOR kinase inhibitor AZD8055 on acquired endocrine resistance in breast cancer in vitro.

Jordan NJ, Dutkowski CM, Barrow D, Mottram HJ, Hutcheson IR, Nicholson RI, Guichard SM, Gee JM.

Breast Cancer Res. 2014 Jan 23;16(1):R12. doi: 10.1186/bcr3604.

20.

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.

Eccles SA, Aboagye EO, Ali S, Anderson AS, Armes J, Berditchevski F, Blaydes JP, Brennan K, Brown NJ, Bryant HE, Bundred NJ, Burchell JM, Campbell AM, Carroll JS, Clarke RB, Coles CE, Cook GJ, Cox A, Curtin NJ, Dekker LV, Silva Idos S, Duffy SW, Easton DF, Eccles DM, Edwards DR, Edwards J, Evans D, Fenlon DF, Flanagan JM, Foster C, Gallagher WM, Garcia-Closas M, Gee JM, Gescher AJ, Goh V, Groves AM, Harvey AJ, Harvie M, Hennessy BT, Hiscox S, Holen I, Howell SJ, Howell A, Hubbard G, Hulbert-Williams N, Hunter MS, Jasani B, Jones LJ, Key TJ, Kirwan CC, Kong A, Kunkler IH, Langdon SP, Leach MO, Mann DJ, Marshall JF, Martin L, Martin SG, Macdougall JE, Miles DW, Miller WR, Morris JR, Moss SM, Mullan P, Natrajan R, O'Connor JP, O'Connor R, Palmieri C, Pharoah PD, Rakha EA, Reed E, Robinson SP, Sahai E, Saxton JM, Schmid P, Smalley MJ, Speirs V, Stein R, Stingl J, Streuli CH, Tutt AN, Velikova G, Walker RA, Watson CJ, Williams KJ, Young LS, Thompson AM.

Breast Cancer Res. 2013 Oct 1;15(5):R92. doi: 10.1186/bcr3493. Review.

21.

Role of endoplasmic reticulum stress induction by the plant toxin, persin, in overcoming resistance to the apoptotic effects of tamoxifen in human breast cancer cells.

McCloy RA, Shelley EJ, Roberts CG, Boslem E, Biden TJ, Nicholson RI, Gee JM, Sutherland RL, Musgrove EA, Burgess A, Butt AJ.

Br J Cancer. 2013 Dec 10;109(12):3034-41. doi: 10.1038/bjc.2013.693. Epub 2013 Oct 31.

22.

Global characterization of signalling networks associated with tamoxifen resistance in breast cancer.

Browne BC, Hochgräfe F, Wu J, Millar EK, Barraclough J, Stone A, McCloy RA, Lee CS, Roberts C, Ali NA, Boulghourjian A, Schmich F, Linding R, Farrow L, Gee JM, Nicholson RI, O'Toole SA, Sutherland RL, Musgrove EA, Butt AJ, Daly RJ.

FEBS J. 2013 Nov;280(21):5237-57. doi: 10.1111/febs.12441. Epub 2013 Aug 19.

23.

BCL-2 hypermethylation is a potential biomarker of sensitivity to antimitotic chemotherapy in endocrine-resistant breast cancer.

Stone A, Cowley MJ, Valdes-Mora F, McCloy RA, Sergio CM, Gallego-Ortega D, Caldon CE, Ormandy CJ, Biankin AV, Gee JM, Nicholson RI, Print CG, Clark SJ, Musgrove EA.

Mol Cancer Ther. 2013 Sep;12(9):1874-85. doi: 10.1158/1535-7163.MCT-13-0012. Epub 2013 Jul 16.

24.

A randomized trial to assess the biological activity of short-term (pre-surgical) fulvestrant 500 mg plus anastrozole versus fulvestrant 500 mg alone or anastrozole alone on primary breast cancer.

Robertson JF, Dixon JM, Sibbering DM, Jahan A, Ellis IO, Channon E, Hyman-Taylor P, Nicholson RI, Gee JM.

Breast Cancer Res. 2013 Mar 5;15(2):R18. doi: 10.1186/bcr3393.

25.

ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer.

Kalyuga M, Gallego-Ortega D, Lee HJ, Roden DL, Cowley MJ, Caldon CE, Stone A, Allerdice SL, Valdes-Mora F, Launchbury R, Statham AL, Armstrong N, Alles MC, Young A, Egger A, Au W, Piggin CL, Evans CJ, Ledger A, Brummer T, Oakes SR, Kaplan W, Gee JM, Nicholson RI, Sutherland RL, Swarbrick A, Naylor MJ, Clark SJ, Carroll JS, Ormandy CJ.

PLoS Biol. 2012;10(12):e1001461. doi: 10.1371/journal.pbio.1001461. Epub 2012 Dec 27.

26.

Tamoxifen-induced epigenetic silencing of oestrogen-regulated genes in anti-hormone resistant breast cancer.

Stone A, Valdés-Mora F, Gee JM, Farrow L, McClelland RA, Fiegl H, Dutkowski C, McCloy RA, Sutherland RL, Musgrove EA, Nicholson RI.

PLoS One. 2012;7(7):e40466. doi: 10.1371/journal.pone.0040466. Epub 2012 Jul 10.

27.

Cyclin E2 overexpression is associated with endocrine resistance but not insensitivity to CDK2 inhibition in human breast cancer cells.

Caldon CE, Sergio CM, Kang J, Muthukaruppan A, Boersma MN, Stone A, Barraclough J, Lee CS, Black MA, Miller LD, Gee JM, Nicholson RI, Sutherland RL, Print CG, Musgrove EA.

Mol Cancer Ther. 2012 Jul;11(7):1488-99. doi: 10.1158/1535-7163.MCT-11-0963. Epub 2012 May 7.

28.

SodA is a major metabolic antioxidant in Brucella abortus 2308 that plays a significant, but limited, role in the virulence of this strain in the mouse model.

Martin DW, Baumgartner JE, Gee JM, Anderson ES, Roop RM 2nd.

Microbiology. 2012 Jul;158(Pt 7):1767-74. doi: 10.1099/mic.0.059584-0. Epub 2012 May 3.

29.

Dose-dependent change in biomarkers during neoadjuvant endocrine therapy with fulvestrant: results from NEWEST, a randomized Phase II study.

Kuter I, Gee JM, Hegg R, Singer CF, Badwe RA, Lowe ES, Emeribe UA, Anderson E, Sapunar F, Finlay P, Nicholson RI, Bines J, Harbeck N.

Breast Cancer Res Treat. 2012 May;133(1):237-46. doi: 10.1007/s10549-011-1947-7.

PMID:
22286314
30.

erbB3 recruitment of insulin receptor substrate 1 modulates insulin-like growth factor receptor signalling in oestrogen receptor-positive breast cancer cell lines.

Knowlden JM, Gee JM, Barrow D, Robertson JF, Ellis IO, Nicholson RI, Hutcheson IR.

Breast Cancer Res. 2011 Sep 22;13(5):R93. doi: 10.1186/bcr3018.

31.

A review of the biological and clinical characteristics of luminal-like oestrogen receptor-positive breast cancer.

Habashy HO, Powe DG, Abdel-Fatah TM, Gee JM, Nicholson RI, Green AR, Rakha EA, Ellis IO.

Histopathology. 2012 May;60(6):854-63. doi: 10.1111/j.1365-2559.2011.03912.x. Epub 2011 Sep 10. Review.

PMID:
21906125
32.

Autoimmune responses to the brain after stroke are associated with worse outcome.

Becker KJ, Kalil AJ, Tanzi P, Zierath DK, Savos AV, Gee JM, Hadwin J, Carter KT, Shibata D, Cain KC.

Stroke. 2011 Oct;42(10):2763-9. doi: 10.1161/STROKEAHA.111.619593. Epub 2011 Jul 28.

33.

A novel g.-1258G>A mutation in a conserved putative regulatory element of PAX9 is associated with autosomal dominant molar hypodontia.

Mendoza-Fandino GA, Gee JM, Ben-Dor S, Gonzalez-Quevedo C, Lee K, Kobayashi Y, Hartiala J, Myers RM, Leal SM, Allayee H, Patel PI.

Clin Genet. 2011 Sep;80(3):265-72. doi: 10.1111/j.1399-0004.2010.01529.x. Epub 2010 Sep 8.

34.

Fulvestrant-induced expression of ErbB3 and ErbB4 receptors sensitizes oestrogen receptor-positive breast cancer cells to heregulin β1.

Hutcheson IR, Goddard L, Barrow D, McClelland RA, Francies HE, Knowlden JM, Nicholson RI, Gee JM.

Breast Cancer Res. 2011 Mar 11;13(2):R29. doi: 10.1186/bcr2848.

35.

Antihormone induced compensatory signalling in breast cancer: an adverse event in the development of endocrine resistance.

Gee JM, Nicholson RI, Barrow D, Dutkowski CM, Goddard L, Jordan NJ, McClelland RA, Knowlden JM, Francies HE, Hiscox SE, Hutcheson IR.

Horm Mol Biol Clin Investig. 2011 Mar 1;5(2):67-77. doi: 10.1515/HMBCI.2011.009.

PMID:
25961242
36.

Post-stroke infection: a role for IL-1ra?

Tanzi P, Cain K, Kalil A, Zierath D, Savos A, Gee JM, Shibata D, Hadwin J, Carter K, Becker K.

Neurocrit Care. 2011 Apr;14(2):244-52. doi: 10.1007/s12028-010-9490-7.

37.

α-MSH: a potential neuroprotective and immunomodulatory agent for the treatment of stroke.

Savos AV, Gee JM, Zierath D, Becker KJ.

J Cereb Blood Flow Metab. 2011 Feb;31(2):606-13. doi: 10.1038/jcbfm.2010.130. Epub 2010 Aug 11.

38.

Long term immunologic consequences of experimental stroke and mucosal tolerance.

Gee JM, Zierath D, Hadwin J, Savos A, Kalil A, Thullbery M, Becker KJ.

Exp Transl Stroke Med. 2009 Oct 21;1:3. doi: 10.1186/2040-7378-1-3.

39.

Sex-dependent species discrimination in auditory forebrain of naturally hybridizing birds.

Gee JM, Tomaszycki ML, Adkins-Regan E.

Brain Behav Evol. 2009;74(4):258-67. doi: 10.1159/000264661. Epub 2009 Dec 8.

40.

CNS immune responses following experimental stroke.

Zierath D, Thullbery M, Hadwin J, Gee JM, Savos A, Kalil A, Becker KJ.

Neurocrit Care. 2010 Apr;12(2):274-84. doi: 10.1007/s12028-009-9270-4. Epub 2009 Aug 28.

41.

Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen.

Habashy HO, Powe DG, Staka CM, Rakha EA, Ball G, Green AR, Aleskandarany M, Paish EC, Douglas Macmillan R, Nicholson RI, Ellis IO, Gee JM.

Breast Cancer Res Treat. 2010 Jan;119(2):283-93. doi: 10.1007/s10549-009-0345-x. Epub 2009 Feb 24.

PMID:
19238537
42.

Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival.

Law JH, Habibi G, Hu K, Masoudi H, Wang MY, Stratford AL, Park E, Gee JM, Finlay P, Jones HE, Nicholson RI, Carboni J, Gottardis M, Pollak M, Dunn SE.

Cancer Res. 2008 Dec 15;68(24):10238-46. doi: 10.1158/0008-5472.CAN-08-2755.

43.

Overexpression of TFAP2C in invasive breast cancer correlates with a poorer response to anti-hormone therapy and reduced patient survival.

Gee JM, Eloranta JJ, Ibbitt JC, Robertson JF, Ellis IO, Williams T, Nicholson RI, Hurst HC.

J Pathol. 2009 Jan;217(1):32-41. doi: 10.1002/path.2430.

44.

In vitro effects on MCF-7 breast cancer cells of signal transduction inhibitor/tamoxifen/eicosapentaenoic acid combinations and their simultaneous delivery across skin.

Davison Z, Dutkowski C, Gee JM, Nicholson RI, Heard CM.

Pharm Res. 2008 Nov;25(11):2516-25. doi: 10.1007/s11095-008-9665-5. Epub 2008 Jul 12.

PMID:
18622691
45.

Flavonoids and intestinal cancers.

Pierini R, Gee JM, Belshaw NJ, Johnson IT.

Br J Nutr. 2008 May;99 E Suppl 1:ES53-9. doi: 10.1017/S0007114508965764. Review.

PMID:
18503735
46.

Incidence of neonatal herpes simplex virus infections in two managed care organizations: implications for surveillance.

Xu F, Gee JM, Naleway A, Zangwill KM, Ackerson B, Eriksen E, Weintraub ES, Hutchins K, Wei F, Berman SM, Markowitz LE.

Sex Transm Dis. 2008 Jun;35(6):592-8. doi: 10.1097/OLQ.0b013e3181666af5.

PMID:
18418296
47.

Induction of immunologic tolerance to myelin basic protein prevents central nervous system autoimmunity and improves outcome after stroke.

Gee JM, Kalil A, Thullbery M, Becker KJ.

Stroke. 2008 May;39(5):1575-82. doi: 10.1161/STROKEAHA.107.501486. Epub 2008 Mar 6.

48.

The Bacteroides fragilis transcriptome response to oxygen and H2O2: the role of OxyR and its effect on survival and virulence.

Sund CJ, Rocha ER, Tzianabos AO, Wells WG, Gee JM, Reott MA, O'Rourke DP, Smith CJ.

Mol Microbiol. 2008 Jan;67(1):129-42. Epub 2007 Nov 28. Erratum in: Mol Microbiol. 2008 Jun;68(5):1340. Tzinabos, Arthur O [corrected to Tzianabos, Arthur O].

49.

Protein kinase C isoform expression as a predictor of disease outcome on endocrine therapy in breast cancer.

Assender JW, Gee JM, Lewis I, Ellis IO, Robertson JF, Nicholson RI.

J Clin Pathol. 2007 Nov;60(11):1216-21.

50.

Insulin receptor substrate-1 involvement in epidermal growth factor receptor and insulin-like growth factor receptor signalling: implication for Gefitinib ('Iressa') response and resistance.

Knowlden JM, Jones HE, Barrow D, Gee JM, Nicholson RI, Hutcheson IR.

Breast Cancer Res Treat. 2008 Sep;111(1):79-91. Epub 2007 Sep 28.

PMID:
17902048

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