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Items: 35

1.

Immunosuppressive therapy for pediatric aplastic anemia: a North American Pediatric Aplastic Anemia Consortium study.

Rogers ZR, Nakano TA, Olson TS, Bertuch AA, Wang W, Gillio A, Coates TD, Chawla A, Castillo P, Kurre P, Gamper C, Bennett CM, Joshi S, Geddis AE, Boklan J, Nalepa G, Rothman JA, Huang JN, Kupfer GM, Cada M, Glader B, Walkovich KJ, Thompson AA, Hanna R, Vlachos A, Malsch M, Weller EA, Williams DA, Shimamura A.

Haematologica. 2019 Apr 4. pii: haematol.2018.206540. doi: 10.3324/haematol.2018.206540. [Epub ahead of print]

2.

Bone Marrow Morphology Associated With Germline RUNX1 Mutations in Patients With Familial Platelet Disorder With Associated Myeloid Malignancy.

Chisholm KM, Denton C, Keel S, Geddis AE, Xu M, Appel BE, Cantor AB, Fleming MD, Shimamura A.

Pediatr Dev Pathol. 2019 Jul-Aug;22(4):315-328. doi: 10.1177/1093526618822108. Epub 2019 Jan 2.

PMID:
30600763
3.

Medical Management of Vascular Anomalies.

Padia R, Bly R, Bull C, Geddis AE, Perkins J.

Curr Treat Options Pediatr. 2018 Jun;4(2):221-236. doi: 10.1007/s40746-018-0130-3. Epub 2018 Apr 27.

4.

Evaluation of the Utility of Bone Marrow Morphology and Ancillary Studies in Pediatric Patients Under Surveillance for Myelodysplastic Syndrome.

Chisholm KM, Xu M, Davis B, Ogi A, Pacheco MC, Geddis AE, Tsuchiya KD, Rutledge JC.

Am J Clin Pathol. 2018 Apr 25;149(6):499-513. doi: 10.1093/ajcp/aqy007.

PMID:
29659673
5.

Allogeneic Hematopoietic Cell Transplantation Using Treosulfan-Based Conditioning for Treatment of Marrow Failure Disorders.

Burroughs LM, Shimamura A, Talano JA, Domm JA, Baker KK, Delaney C, Frangoul H, Margolis DA, Baker KS, Nemecek ER, Geddis AE, Sandmaier BM, Deeg HJ, Storb R, Woolfrey AE.

Biol Blood Marrow Transplant. 2017 Oct;23(10):1669-1677. doi: 10.1016/j.bbmt.2017.06.002. Epub 2017 Jun 7.

6.

A novel compound heterozygous form of severe protein C deficiency causing bleeding without purpura fulminans.

Herrick NL, Geddis AE, Lovejoy AE, Kim J, Schiff D, Thornburg CD.

Pediatr Blood Cancer. 2017 Nov;64(11). doi: 10.1002/pbc.26626. Epub 2017 May 9. No abstract available.

PMID:
28485122
7.

ANKRD26-related thrombocytopenia and myeloid malignancies.

Noris P, Favier R, Alessi MC, Geddis AE, Kunishima S, Heller PG, Giordano P, Niederhoffer KY, Bussel JB, Podda GM, Vianelli N, Kersseboom R, Pecci A, Gnan C, Marconi C, Auvrignon A, Cohen W, Yu JC, Iguchi A, Miller Imahiyerobo A, Boehlen F, Ghalloussi D, De Rocco D, Magini P, Civaschi E, Biino G, Seri M, Savoia A, Balduini CL.

Blood. 2013 Sep 12;122(11):1987-9. doi: 10.1182/blood-2013-04-499319. No abstract available.

8.

Inherited thrombocytopenias: an approach to diagnosis and management.

Geddis AE.

Int J Lab Hematol. 2013 Feb;35(1):14-25. doi: 10.1111/j.1751-553X.2012.01454.x. Epub 2012 Jul 30. Review.

PMID:
22846067
9.

A POTEntial new gene for thrombocytopenia.

Geddis AE.

Blood. 2011 Jun 16;117(24):6406-8. doi: 10.1182/blood-2011-04-348383. No abstract available.

10.

Congenital amegakaryocytic thrombocytopenia.

Geddis AE.

Pediatr Blood Cancer. 2011 Aug;57(2):199-203. doi: 10.1002/pbc.22927. Epub 2011 Feb 18. Review.

PMID:
21337678
11.

Shedding light on endomitosis.

Geddis AE.

Blood. 2010 Sep 30;116(13):2202-3. doi: 10.1182/blood-2010-07-293449. No abstract available.

12.

Megakaryopoiesis.

Geddis AE.

Semin Hematol. 2010 Jul;47(3):212-9. doi: 10.1053/j.seminhematol.2010.03.001. Review.

14.

Ubiquitination and degradation of the thrombopoietin receptor c-Mpl.

Saur SJ, Sangkhae V, Geddis AE, Kaushansky K, Hitchcock IS.

Blood. 2010 Feb 11;115(6):1254-63. doi: 10.1182/blood-2009-06-227033. Epub 2009 Oct 30.

15.

The regulation of proplatelet production.

Geddis AE.

Haematologica. 2009 Jun;94(6):756-9. doi: 10.3324/haematol.2009.006577. No abstract available.

16.

Congenital amegakaryocytic thrombocytopenia and thrombocytopenia with absent radii.

Geddis AE.

Hematol Oncol Clin North Am. 2009 Apr;23(2):321-31. doi: 10.1016/j.hoc.2009.01.012. Review.

17.

Compound heterozygous c-Mpl mutations in a child with congenital amegakaryocytic thrombocytopenia: functional characterization and a review of the literature.

Fox NE, Chen R, Hitchcock I, Keates-Baleeiro J, Frangoul H, Geddis AE.

Exp Hematol. 2009 Apr;37(4):495-503. doi: 10.1016/j.exphem.2009.01.001. Review.

18.

Inhibition of GSK-3beta promotes survival and proliferation of megakaryocytic cells through a beta-catenin-independent pathway.

Soda M, Willert K, Kaushansky K, Geddis AE.

Cell Signal. 2008 Dec;20(12):2317-23. doi: 10.1016/j.cellsig.2008.09.001. Epub 2008 Sep 6.

19.
20.

Diagnosis of immune thrombocytopenic purpura in children.

Geddis AE, Balduini CL.

Curr Opin Hematol. 2007 Sep;14(5):520-5. Review.

PMID:
17934362
21.

Immunology. The root of platelet production.

Geddis AE, Kaushansky K.

Science. 2007 Sep 21;317(5845):1689-91. No abstract available.

PMID:
17885117
22.

Endomitotic megakaryocytes that form a bipolar spindle exhibit cleavage furrow ingression followed by furrow regression.

Geddis AE, Fox NE, Tkachenko E, Kaushansky K.

Cell Cycle. 2007 Feb 15;6(4):455-60. Epub 2007 Feb 8.

PMID:
17312391
23.
24.

Endomitotic megakaryocytes form a midzone in anaphase but have a deficiency in cleavage furrow formation.

Geddis AE, Kaushansky K.

Cell Cycle. 2006 Mar;5(5):538-45. Epub 2006 Mar 1.

PMID:
16552179
25.
26.
27.

The molecular basis of congenital thrombocytopenias: insights into megakaryopoiesis.

Geddis AE.

Hematology. 2005;10 Suppl 1:299-305. Review. No abstract available.

PMID:
16188691
28.

Megakaryocytes express functional Aurora-B kinase in endomitosis.

Geddis AE, Kaushansky K.

Blood. 2004 Aug 15;104(4):1017-24. Epub 2004 May 6.

29.

Inherited thrombocytopenias: toward a molecular understanding of disorders of platelet production.

Geddis AE, Kaushansky K.

Curr Opin Pediatr. 2004 Feb;16(1):15-22. Review.

PMID:
14758109
30.

Cross-reactivity between erythropoietin and thrombopoietin at the level of Mpl does not account for the thrombocytosis seen in iron deficiency.

Geddis AE, Kaushansky K.

J Pediatr Hematol Oncol. 2003 Nov;25(11):919-20; author reply 920. No abstract available.

PMID:
14608207
31.

Studies with chimeric Mpl/JAK2 receptors indicate that both JAK2 and the membrane-proximal domain of Mpl are required for cellular proliferation.

Drachman JG, Miyakawa Y, Luthi JN, Dahlen DD, Raney A, Geddis AE, Kaushansky K.

J Biol Chem. 2002 Jun 28;277(26):23544-53. Epub 2002 Apr 29.

32.

Thrombopoietin: a pan-hematopoietic cytokine.

Geddis AE, Linden HM, Kaushansky K.

Cytokine Growth Factor Rev. 2002 Feb;13(1):61-73. Review.

PMID:
11750880

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