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Items: 1 to 50 of 356

1.

Incidence of epidural hematoma from use of epidural analgesia for hepatic resection surgery: A retrospective study.

Su J, Soliz JM, Popat KU, Gebhardt R.

J Clin Anesth. 2020 Jan 16;62:109719. doi: 10.1016/j.jclinane.2020.109719. [Epub ahead of print] No abstract available.

PMID:
31955129
2.

Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human.

Kolbe E, Aleithe S, Rennert C, Spormann L, Ott F, Meierhofer D, Gajowski R, Stöpel C, Hoehme S, Kücken M, Brusch L, Seifert M, von Schoenfels W, Schafmayer C, Brosch M, Hofmann U, Damm G, Seehofer D, Hampe J, Gebhardt R, Matz-Soja M.

Cell Rep. 2019 Dec 24;29(13):4553-4567.e7. doi: 10.1016/j.celrep.2019.11.104.

3.

Influence of Liver Fibrosis on Lobular Zonation.

Ghallab A, Myllys M, Holland CH, Zaza A, Murad W, Hassan R, Ahmed YA, Abbas T, Abdelrahim EA, Schneider KM, Matz-Soja M, Reinders J, Gebhardt R, Berres ML, Hatting M, Drasdo D, Saez-Rodriguez J, Trautwein C, Hengstler JG.

Cells. 2019 Dec 2;8(12). pii: E1556. doi: 10.3390/cells8121556.

4.

Complications of Postoperative Epidural Analgesia For Oncologic Surgery: A Review of 18,895 Cases.

Su J, Soliz JM, Popat KU, Gebhardt R.

Clin J Pain. 2019 Jul;35(7):589-593. doi: 10.1097/AJP.0000000000000718.

PMID:
31008725
5.

β-Catenin and Yes-Associated Protein 1 Cooperate in Hepatoblastoma Pathogenesis.

Min Q, Molina L, Li J, Adebayo Michael AO, Russell JO, Preziosi ME, Singh S, Poddar M, Matz-Soja M, Ranganathan S, Bell AW, Gebhardt R, Gaunitz F, Yu J, Tao J, Monga SP.

Am J Pathol. 2019 May;189(5):1091-1104. doi: 10.1016/j.ajpath.2019.02.002. Epub 2019 Feb 19. Erratum in: Am J Pathol. 2019 Aug;189(8):1680.

PMID:
30794807
6.

Tick-tock hedgehog-mutual crosstalk with liver circadian clock promotes liver steatosis.

Marbach-Breitrück E, Matz-Soja M, Abraham U, Schmidt-Heck W, Sales S, Rennert C, Kern M, Aleithe S, Spormann L, Thiel C, Gerlini R, Arnold K, Klöting N, Guthke R, Rozman D, Teperino R, Shevchenko A, Kramer A, Gebhardt R.

J Hepatol. 2019 Jun;70(6):1192-1202. doi: 10.1016/j.jhep.2019.01.022. Epub 2019 Feb 1.

PMID:
30711403
7.

The Diurnal Timing of Starvation Differently Impacts Murine Hepatic Gene Expression and Lipid Metabolism - A Systems Biology Analysis Using Self-Organizing Maps.

Rennert C, Vlaic S, Marbach-Breitrück E, Thiel C, Sales S, Shevchenko A, Gebhardt R, Matz-Soja M.

Front Physiol. 2018 Sep 10;9:1180. doi: 10.3389/fphys.2018.01180. eCollection 2018.

8.

Epidural Analgesia and Subcutaneous Heparin 3 Times Daily in Cancer Patients With Acute Postoperative Pain.

Su J, Soliz JM, Popat KU, Gebhardt R.

Anesth Analg. 2018 Oct;127(4):e57-e59. doi: 10.1213/ANE.0000000000003603.

PMID:
29958215
9.

The Wnt/β-catenin pathway determines the predisposition and efficiency of liver-to-pancreas reprogramming.

Cohen H, Barash H, Meivar-Levy I, Molakandov K, Ben-Shimon M, Gurevich M, Zoabi F, Har-Zahav A, Gebhardt R, Gaunitz F, Gurevich M, Mor E, Ravassard P, Greenberger S, Ferber S.

Hepatology. 2018 Oct;68(4):1589-1603. doi: 10.1002/hep.29827. Epub 2018 May 24.

PMID:
29394503
10.

On the complexity of measuring forests microclimate and interpreting its relevance in habitat ecology: the example of Ixodes ricinus ticks.

Boehnke D, Gebhardt R, Petney T, Norra S.

Parasit Vectors. 2017 Nov 6;10(1):549. doi: 10.1186/s13071-017-2498-5.

11.

Oleate ameliorates palmitate-induced reduction of NAMPT activity and NAD levels in primary human hepatocytes and hepatocarcinoma cells.

Penke M, Schuster S, Gorski T, Gebhardt R, Kiess W, Garten A.

Lipids Health Dis. 2017 Oct 3;16(1):191. doi: 10.1186/s12944-017-0583-6.

12.

Influence of β-lactoglobulin and calcium chloride on the molecular structure and interactions of casein micelles.

Zhuang Y, Ueda I, Kulozik U, Gebhardt R.

Int J Biol Macromol. 2018 Feb;107(Pt A):560-566. doi: 10.1016/j.ijbiomac.2017.09.021. Epub 2017 Sep 12.

PMID:
28916382
13.

Demonstration of a beam loaded nanocoulomb-class laser wakefield accelerator.

Couperus JP, Pausch R, Köhler A, Zarini O, Krämer JM, Garten M, Huebl A, Gebhardt R, Helbig U, Bock S, Zeil K, Debus A, Bussmann M, Schramm U, Irman A.

Nat Commun. 2017 Sep 8;8(1):487. doi: 10.1038/s41467-017-00592-7.

14.

Efficient laser-driven proton acceleration from cylindrical and planar cryogenic hydrogen jets.

Obst L, Göde S, Rehwald M, Brack FE, Branco J, Bock S, Bussmann M, Cowan TE, Curry CB, Fiuza F, Gauthier M, Gebhardt R, Helbig U, Huebl A, Hübner U, Irman A, Kazak L, Kim JB, Kluge T, Kraft S, Loeser M, Metzkes J, Mishra R, Rödel C, Schlenvoigt HP, Siebold M, Tiggesbäumker J, Wolter S, Ziegler T, Schramm U, Glenzer SH, Zeil K.

Sci Rep. 2017 Aug 31;7(1):10248. doi: 10.1038/s41598-017-10589-3.

15.

Conditional loss of hepatocellular Hedgehog signaling in female mice leads to the persistence of hepatic steroidogenesis, androgenization and infertility.

Rennert C, Eplinius F, Hofmann U, Johänning J, Rolfs F, Schmidt-Heck W, Guthke R, Gebhardt R, Ricken AM, Matz-Soja M.

Arch Toxicol. 2017 Nov;91(11):3677-3687. doi: 10.1007/s00204-017-1999-5. Epub 2017 May 30.

PMID:
28560483
16.

Hedgehog signalling in myeloid cells impacts on body weight, adipose tissue inflammation and glucose metabolism.

Braune J, Weyer U, Matz-Soja M, Hobusch C, Kern M, Kunath A, Klöting N, Kralisch S, Blüher M, Gebhardt R, Zavros Y, Bechmann I, Gericke M.

Diabetologia. 2017 May;60(5):889-899. doi: 10.1007/s00125-017-4223-5. Epub 2017 Feb 23.

PMID:
28233033
17.

Disrupting Hepatocyte Cyp51 from Cholesterol Synthesis Leads to Progressive Liver Injury in the Developing Mouse and Decreases RORC Signalling.

Urlep Ž, Lorbek G, Perše M, Jeruc J, Juvan P, Matz-Soja M, Gebhardt R, Björkhem I, Hall JA, Bonneau R, Littman DR, Rozman D.

Sci Rep. 2017 Jan 18;7:40775. doi: 10.1038/srep40775.

18.

Dietary fructose as a risk factor for non-alcoholic fatty liver disease (NAFLD).

Alwahsh SM, Gebhardt R.

Arch Toxicol. 2017 Apr;91(4):1545-1563. doi: 10.1007/s00204-016-1892-7. Epub 2016 Dec 19. Review.

PMID:
27995280
19.

Tailoring Nanoscale Morphology of Polymer:Fullerene Blends Using Electrostatic Field.

Elshobaki M, Gebhardt R, Carr J, Lindemann W, Wang W, Grieser E, Venkatesan S, Ngo E, Bhattacharjee U, Strzalka J, Jiang Z, Qiao Q, Petrich J, Vaknin D, Chaudhary S.

ACS Appl Mater Interfaces. 2017 Jan 25;9(3):2678-2685. doi: 10.1021/acsami.6b10870. Epub 2016 Dec 16.

PMID:
27982563
20.

Cancer Seeding Risk from an Epidural Blood Patch in Patients with Leukemia or Lymphoma.

Demaree CJ, Soliz JM, Gebhardt R.

Pain Med. 2017 Apr 1;18(4):786-790. doi: 10.1093/pm/pnw218.

PMID:
27558856
21.

Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue.

Godoy P, Widera A, Schmidt-Heck W, Campos G, Meyer C, Cadenas C, Reif R, Stöber R, Hammad S, Pütter L, Gianmoena K, Marchan R, Ghallab A, Edlund K, Nüssler A, Thasler WE, Damm G, Seehofer D, Weiss TS, Dirsch O, Dahmen U, Gebhardt R, Chaudhari U, Meganathan K, Sachinidis A, Kelm J, Hofmann U, Zahedi RP, Guthke R, Blüthgen N, Dooley S, Hengstler JG.

Arch Toxicol. 2016 Oct;90(10):2513-29. doi: 10.1007/s00204-016-1761-4. Epub 2016 Jun 23.

22.

Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis.

Matz-Soja M, Rennert C, Schönefeld K, Aleithe S, Boettger J, Schmidt-Heck W, Weiss TS, Hovhannisyan A, Zellmer S, Klöting N, Schulz A, Kratzsch J, Guthke R, Gebhardt R.

Elife. 2016 May 17;5. pii: e13308. doi: 10.7554/eLife.13308.

23.

Characterization of chemical-induced sterile inflammation in vitro: application of the model compound ketoconazole in a human hepatic co-culture system.

Wewering F, Jouy F, Wissenbach DK, Gebauer S, Blüher M, Gebhardt R, Pirow R, von Bergen M, Kalkhof S, Luch A, Zellmer S.

Arch Toxicol. 2017 Feb;91(2):799-810. doi: 10.1007/s00204-016-1686-y. Epub 2016 Mar 10.

PMID:
26965496
24.

Stereological assessment of sexual dimorphism in the rat liver reveals differences in hepatocytes and Kupffer cells but not hepatic stellate cells.

Marcos R, Lopes C, Malhão F, Correia-Gomes C, Fonseca S, Lima M, Gebhardt R, Rocha E.

J Anat. 2016 Jun;228(6):996-1005. doi: 10.1111/joa.12448. Epub 2016 Feb 19.

25.

Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases.

Ghallab A, Cellière G, Henkel SG, Driesch D, Hoehme S, Hofmann U, Zellmer S, Godoy P, Sachinidis A, Blaszkewicz M, Reif R, Marchan R, Kuepfer L, Häussinger D, Drasdo D, Gebhardt R, Hengstler JG.

J Hepatol. 2016 Apr;64(4):860-71. doi: 10.1016/j.jhep.2015.11.018. Epub 2015 Nov 27.

26.

Optimality in the zonation of ammonia detoxification in rodent liver.

Bartl M, Pfaff M, Ghallab A, Driesch D, Henkel SG, Hengstler JG, Schuster S, Kaleta C, Gebhardt R, Zellmer S, Li P.

Arch Toxicol. 2015 Nov;89(11):2069-78. doi: 10.1007/s00204-015-1596-4. Epub 2015 Oct 5.

PMID:
26438405
27.

Estimating Ixodes ricinus densities on the landscape scale.

Boehnke D, Brugger K, Pfäffle M, Sebastian P, Norra S, Petney T, Oehme R, Littwin N, Lebl K, Raith J, Walter M, Gebhardt R, Rubel F.

Int J Health Geogr. 2015 Aug 14;14:23. doi: 10.1186/s12942-015-0015-7.

28.

Liposomes as carriers: not as innocent as one would like.

Gebhardt R, Matz-Soja M.

Arch Toxicol. 2015 Sep;89(9):1399-400. doi: 10.1007/s00204-015-1574-x. Epub 2015 Aug 6. No abstract available.

PMID:
26245945
29.

The Combined Effect of High Hydrostatic Pressure and Calcium Salts on the Stability, Solubility and Gel Formation of β-Lactoglobulin.

Saalfeld D, Riegel I, Kulozik U, Gebhardt R.

Foods. 2015 Jun 8;4(2):229-239. doi: 10.3390/foods4020229.

30.

Fuzzy modeling reveals a dynamic self-sustaining network of the GLI transcription factors controlling important metabolic regulators in adult mouse hepatocytes.

Schmidt-Heck W, Matz-Soja M, Aleithe S, Marbach E, Guthke R, Gebhardt R.

Mol Biosyst. 2015 Aug;11(8):2190-7. doi: 10.1039/c5mb00129c.

PMID:
26010061
31.

Using computed tomography scans and patient demographic data to estimate thoracic epidural space depth.

Kosturakis A, Soliz J, Su J, Cata JP, Feng L, Harun N, Amsbaugh A, Gebhardt R.

Pain Res Treat. 2015;2015:470240. doi: 10.1155/2015/470240. Epub 2015 Apr 16.

32.

Lessons from hepatocyte-specific Cyp51 knockout mice: impaired cholesterol synthesis leads to oval cell-driven liver injury.

Lorbek G, Perše M, Jeruc J, Juvan P, Gutierrez-Mariscal FM, Lewinska M, Gebhardt R, Keber R, Horvat S, Björkhem I, Rozman D.

Sci Rep. 2015 Mar 5;5:8777. doi: 10.1038/srep08777.

33.

Zonation of hepatic fatty acid metabolism - The diversity of its regulation and the benefit of modeling.

Schleicher J, Tokarski C, Marbach E, Matz-Soja M, Zellmer S, Gebhardt R, Schuster S.

Biochim Biophys Acta. 2015 May;1851(5):641-56. doi: 10.1016/j.bbalip.2015.02.004. Epub 2015 Feb 9. Review.

PMID:
25677822
34.

FK866-induced NAMPT inhibition activates AMPK and downregulates mTOR signaling in hepatocarcinoma cells.

Schuster S, Penke M, Gorski T, Gebhardt R, Weiss TS, Kiess W, Garten A.

Biochem Biophys Res Commun. 2015 Mar 6;458(2):334-40. doi: 10.1016/j.bbrc.2015.01.111. Epub 2015 Feb 3.

PMID:
25656579
35.

Reducing optical losses in organic solar cells using microlens arrays: theoretical and experimental investigation of microlens dimensions.

Chen Y, Elshobaki M, Gebhardt R, Bergeson S, Noack M, Park JM, Hillier AC, Ho KM, Biswas R, Chaudhary S.

Phys Chem Chem Phys. 2015 Feb 7;17(5):3723-30. doi: 10.1039/c4cp05221h. Epub 2015 Jan 5.

PMID:
25556607
36.

Application of confocal Raman microscopy to investigate casein micro-particles in blend casein/pectin films.

Zhuang Y, Sterr J, Kulozik U, Gebhardt R.

Int J Biol Macromol. 2015 Mar;74:44-8. doi: 10.1016/j.ijbiomac.2014.11.017. Epub 2014 Dec 4.

PMID:
25482531
37.

A systematic evaluation of the use of physiologically based pharmacokinetic modeling for cross-species extrapolation.

Thiel C, Schneckener S, Krauss M, Ghallab A, Hofmann U, Kanacher T, Zellmer S, Gebhardt R, Hengstler JG, Kuepfer L.

J Pharm Sci. 2015 Jan;104(1):191-206. doi: 10.1002/jps.24214. Epub 2014 Nov 12.

PMID:
25393841
38.

The virtual liver: state of the art and future perspectives.

Drasdo D, Bode J, Dahmen U, Dirsch O, Dooley S, Gebhardt R, Ghallab A, Godoy P, Häussinger D, Hammad S, Hoehme S, Holzhütter HG, Klingmüller U, Kuepfer L, Timmer J, Zerial M, Hengstler JG.

Arch Toxicol. 2014 Dec;88(12):2071-5. doi: 10.1007/s00204-014-1384-6. No abstract available.

PMID:
25331938
39.

Global increase of p16INK4a in APC-deficient mouse liver drives clonal growth of p16INK4a-negative tumors.

Ueberham E, Glöckner P, Göhler C, Straub BK, Teupser D, Schönig K, Braeuning A, Höhn AK, Jerchow B, Birchmeier W, Gaunitz F, Arendt T, Sansom O, Gebhardt R, Ueberham U.

Mol Cancer Res. 2015 Feb;13(2):239-49. doi: 10.1158/1541-7786.MCR-14-0278-T. Epub 2014 Sep 30.

40.

The many faces of Hedgehog signalling in the liver: recent progress reveals striking cellular diversity and the importance of microenvironments.

Matz-Soja M, Gebhardt R.

J Hepatol. 2014 Dec;61(6):1449-50. doi: 10.1016/j.jhep.2014.06.041. Epub 2014 Aug 23. No abstract available.

41.

Liver zonation: Novel aspects of its regulation and its impact on homeostasis.

Gebhardt R, Matz-Soja M.

World J Gastroenterol. 2014 Jul 14;20(26):8491-504. doi: 10.3748/wjg.v20.i26.8491. Review.

42.

Virus particle assembly into crystalline domains enabled by the coffee ring effect.

Gebhardt R, Teulon JM, Pellequer JL, Burghammer M, Colletier JP, Riekel C.

Soft Matter. 2014 Aug 14;10(30):5458-62. doi: 10.1039/c4sm00414k.

PMID:
24930741
43.

Speeding up hepatocyte proliferation: how triiodothyronine and β-catenin join forces.

Gebhardt R.

Hepatology. 2014 Jun;59(6):2074-6. doi: 10.1002/hep.26984. Epub 2014 Apr 29. No abstract available.

PMID:
24919451
44.

[The ecology of ticks, tick-borne diseases and biological tick control in Baden-Württemberg].

Sebastian P, Mackenstedt U, Wassermann M, Wurst E, Hartelt K, Petney T, Pfäffle M, Littwin N, Steidle JL, Selzer P, Norra S, Böhnke D, Gebhardt R, Kahl O, Dautel H, Oehme R.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2014 May;57(5):549-56. doi: 10.1007/s00103-013-1929-5. German.

PMID:
24781912
45.

Liver-restricted Repin1 deficiency improves whole-body insulin sensitivity, alters lipid metabolism, and causes secondary changes in adipose tissue in mice.

Kern M, Kosacka J, Hesselbarth N, Brückner J, Heiker JT, Flehmig G, Klöting I, Kovacs P, Matz-Soja M, Gebhardt R, Krohn K, Sales S, Abshagen K, Shevchenko A, Stumvoll M, Blüher M, Klöting N.

Diabetes. 2014 Oct;63(10):3295-309. doi: 10.2337/db13-0933. Epub 2014 Apr 23.

46.

Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue microarchitecture by image processing and analysis.

Hammad S, Hoehme S, Friebel A, von Recklinghausen I, Othman A, Begher-Tibbe B, Reif R, Godoy P, Johann T, Vartak A, Golka K, Bucur PO, Vibert E, Marchan R, Christ B, Dooley S, Meyer C, Ilkavets I, Dahmen U, Dirsch O, Böttger J, Gebhardt R, Drasdo D, Hengstler JG.

Arch Toxicol. 2014 May;88(5):1161-83. doi: 10.1007/s00204-014-1243-5. Epub 2014 Apr 19.

47.

Integrated metabolic spatial-temporal model for the prediction of ammonia detoxification during liver damage and regeneration.

Schliess F, Hoehme S, Henkel SG, Ghallab A, Driesch D, Böttger J, Guthke R, Pfaff M, Hengstler JG, Gebhardt R, Häussinger D, Drasdo D, Zellmer S.

Hepatology. 2014 Dec;60(6):2040-51. doi: 10.1002/hep.27136. Epub 2014 May 12.

48.

Recent advances in select interventional approaches to cancer-related pain.

Chai T, Smith LS, Gebhardt R.

Pain Manag. 2013 Nov;3(6):503-9. doi: 10.2217/pmt.13.54.

PMID:
24654905
49.

Resveratrol differentially regulates NAMPT and SIRT1 in Hepatocarcinoma cells and primary human hepatocytes.

Schuster S, Penke M, Gorski T, Petzold-Quinque S, Damm G, Gebhardt R, Kiess W, Garten A.

PLoS One. 2014 Mar 6;9(3):e91045. doi: 10.1371/journal.pone.0091045. eCollection 2014.

50.

Simulation of the shape and size of casein micelles in a film state.

Gebhardt R, Kulozik U.

Food Funct. 2014 Apr;5(4):780-5. doi: 10.1039/c3fo60369e.

PMID:
24569528

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