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Items: 1 to 50 of 95

1.

Citrofulvicin, an Antiosteoporotic Polyketide from Penicillium velutinum.

Chen Y, Jiang N, Wei YJ, Li X, Ge HM, Jiao RH, Tan RX.

Org Lett. 2018 Jun 21. doi: 10.1021/acs.orglett.8b01272. [Epub ahead of print]

PMID:
29927257
2.

Genome Mining and Comparative Biosynthesis of Meroterpenoids from Two Phylogenetically Distinct Fungi.

Zhang X, Wang TT, Xu QL, Xiong Y, Zhang L, Han H, Xu K, Guo WJ, Xu Q, Tan RX, Ge HM.

Angew Chem Int Ed Engl. 2018 May 24. doi: 10.1002/anie.201804317. [Epub ahead of print]

PMID:
29797385
3.

Discovery, Biosynthesis, and Heterologous Production of Streptoseomycin, an Anti-Microaerophilic Bacteria Macrodilactone.

Zhang B, Wang KB, Wang W, Bi SF, Mei YN, Deng XZ, Jiao RH, Tan RX, Ge HM.

Org Lett. 2018 May 18;20(10):2967-2971. doi: 10.1021/acs.orglett.8b01006. Epub 2018 Apr 26.

PMID:
29697266
4.

Acaulins A and B, Trimeric Macrodiolides from Acaulium sp. H-JQSF.

Wang TT, Wei YJ, Ge HM, Jiao RH, Tan RX.

Org Lett. 2018 Apr 20;20(8):2490-2493. doi: 10.1021/acs.orglett.8b00883. Epub 2018 Apr 6.

PMID:
29624065
5.

Structure and biosynthesis of mayamycin B, a new polyketide with antibacterial activity from Streptomyces sp. 120454.

Bo ST, Xu ZF, Yang L, Cheng P, Tan RX, Jiao RH, Ge HM.

J Antibiot (Tokyo). 2018 Jun;71(6):601-605. doi: 10.1038/s41429-018-0039-x. Epub 2018 Mar 7.

PMID:
29515228
6.

Ginsenoside Rh2 inhibits vascular endothelial growth factor-induced corneal neovascularization.

Zhang XP, Li KR, Yu Q, Yao MD, Ge HM, Li XM, Jiang Q, Yao J, Cao C.

FASEB J. 2018 Feb 20:fj201701074RR. doi: 10.1096/fj.201701074RR. [Epub ahead of print]

PMID:
29465315
7.

Long non-coding RNA MEG3 silencing protects against light-induced retinal degeneration.

Zhu YX, Yao J, Liu C, Hu HT, Li XM, Ge HM, Zhou YF, Shan K, Jiang Q, Yan B.

Biochem Biophys Res Commun. 2018 Feb 19;496(4):1236-1242. doi: 10.1016/j.bbrc.2018.01.177. Epub 2018 Feb 1.

PMID:
29409883
8.

New Antibacterial Phenone Derivatives Asperphenone A-C from Mangrove-Derived Fungus Aspergillus sp. YHZ-1.

Guo ZK, Zhou YQ, Han H, Wang W, Xiang L, Deng XZ, Ge HM, Jiao RH.

Mar Drugs. 2018 Jan 30;16(2). pii: E45. doi: 10.3390/md16020045.

9.

Acaulide, an Osteogenic Macrodiolide from Acaulium sp. H-JQSF, an Isopod-Associated Fungus.

Wang TT, Wei YJ, Ge HM, Jiao RH, Tan RX.

Org Lett. 2018 Feb 16;20(4):1007-1010. doi: 10.1021/acs.orglett.7b03949. Epub 2018 Jan 27.

PMID:
29376657
10.

Amycolamycins A and B, Two Enediyne-Derived Compounds from a Locust-Associated Actinomycete.

Ma SY, Xiao YS, Zhang B, Shao FL, Guo ZK, Zhang JJ, Jiao RH, Sun Y, Xu Q, Tan RX, Ge HM.

Org Lett. 2017 Nov 17;19(22):6208-6211. doi: 10.1021/acs.orglett.7b03113. Epub 2017 Nov 1.

PMID:
29090939
11.

Strepchazolins A and B: Two New Alkaloids from a Marine Streptomyces chartreusis NA02069.

Yang CL, Wang YS, Liu CL, Zeng YJ, Cheng P, Jiao RH, Bao SX, Huang HQ, Tan RX, Ge HM.

Mar Drugs. 2017 Aug 2;15(8). pii: E244. doi: 10.3390/md15080244.

12.

Anti-hyperuricemic and anti-inflammatory actions of vaticaffinol isolated from Dipterocarpus alatus in hyperuricemic mice.

Chen YS, Chen CJ, Yan W, Ge HM, Kong LD.

Chin J Nat Med. 2017 May;15(5):330-340. doi: 10.1016/S1875-5364(17)30053-5.

PMID:
28558868
13.

Novel chaetospirolactone and orsellide F from an endophytic fungus Chaetomium sp.

Xu QL, Xiao YS, Shen Y, Wu HM, Zhang X, Deng XZ, Wang TT, Li W, Tan RX, Jiao RH, Ge HM.

J Asian Nat Prod Res. 2018 Mar;20(3):234-241. doi: 10.1080/10286020.2017.1320548. Epub 2017 May 8.

PMID:
28478698
14.

Rifamorpholines A-E, potential antibiotics from locust-associated actinobacteria Amycolatopsis sp. Hca4.

Xiao YS, Zhang B, Zhang M, Guo ZK, Deng XZ, Shi J, Li W, Jiao RH, Tan RX, Ge HM.

Org Biomol Chem. 2017 May 10;15(18):3909-3916. doi: 10.1039/c7ob00614d.

PMID:
28422262
15.

Aurachin SS, a new antibiotic from Streptomyces sp. NA04227.

Zhang M, Yang CL, Xiao YS, Zhang B, Deng XZ, Yang L, Shi J, Wang YS, Li W, Jiao RH, Tan RX, Ge HM.

J Antibiot (Tokyo). 2017 Jul;70(7):853-855. doi: 10.1038/ja.2017.50. Epub 2017 Apr 19. No abstract available.

PMID:
28420868
16.

Polyketides from mantis-associated fungus Daldinia eschscholzii IFB-TL01.

Wang G, Fan JY, Zhang WJ, Hua CP, Chen CJ, Yan W, Ge HM, Jiao RH, Tan RX.

Chem Biodivers. 2015 Sep;12(9):1349-55. doi: 10.1002/cbdv.201400414.

PMID:
26363879
17.

Actinotetraose L, a new tetrasaccharide derivative isolated from the mycelia of Amycolatopsis sp. HCa1.

Guo ZK, Yan W, Tan RX, Ge HM.

J Asian Nat Prod Res. 2015;17(11):1109-13. doi: 10.1080/10286020.2015.1052413. Epub 2015 Jul 28.

PMID:
26218137
18.

Synthesis and evaluation of 8,4'-dideshydroxy-leinamycin revealing new insights into the structure-activity relationship of the anticancer natural product leinamycin.

Liu T, Ma M, Ge HM, Yang C, Cleveland J, Shen B.

Bioorg Med Chem Lett. 2015 Nov 1;25(21):4899-4902. doi: 10.1016/j.bmcl.2015.05.078. Epub 2015 May 30.

19.

New ansamycin analogues from the mutant strain of Streptomyces seoulensis.

Song YN, Zhang WJ, Bi SF, Jiao RH, Tan RX, Ge HM.

J Antibiot (Tokyo). 2015 Dec;68(12):757-9. doi: 10.1038/ja.2015.65. Epub 2015 Jun 10. No abstract available.

PMID:
26058569
20.

Malibatol A regulates microglia M1/M2 polarization in experimental stroke in a PPARγ-dependent manner.

Pan J, Jin JL, Ge HM, Yin KL, Chen X, Han LJ, Chen Y, Qian L, Li XX, Xu Y.

J Neuroinflammation. 2015 Mar 14;12:51. doi: 10.1186/s12974-015-0270-3.

21.

Drimane sesquiterpenoids from the Aspergillus oryzae QXPC-4.

Ren R, Chen CJ, Hu SS, Ge HM, Zhu WY, Tan RX, Jiao RH.

Chem Biodivers. 2015 Mar;12(3):371-9. doi: 10.1002/cbdv.201400119.

PMID:
25766910
22.

Antiviral activity of Paulownia tomentosa against enterovirus 71 of hand, foot, and mouth disease.

Ji P, Chen C, Hu Y, Zhan Z, Pan W, Li R, Li E, Ge HM, Yang G.

Biol Pharm Bull. 2015;38(1):1-6. doi: 10.1248/bpb.b14-00357.

23.

New ansamycin derivatives generated by simultaneous mutasynthesis.

Song YN, Jiao RH, Zhang WJ, Zhao GY, Dou H, Jiang R, Zhang AH, Hou YY, Bi SF, Ge HM, Tan RX.

Org Lett. 2015 Feb 6;17(3):556-9. doi: 10.1021/ol5035639. Epub 2015 Jan 22.

PMID:
25611625
24.

Aspergiloid I, an unprecedented spirolactone norditerpenoid from the plant-derived endophytic fungus Aspergillus sp. YXf3.

Guo ZK, Wang R, Huang W, Li XN, Jiang R, Tan RX, Ge HM.

Beilstein J Org Chem. 2014 Nov 17;10:2677-82. doi: 10.3762/bjoc.10.282. eCollection 2014.

25.

Pictet-Spengler reaction-based biosynthetic machinery in fungi.

Yan W, Ge HM, Wang G, Jiang N, Mei YN, Jiang R, Li SJ, Chen CJ, Jiao RH, Xu Q, Ng SW, Tan RX.

Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18138-43. doi: 10.1073/pnas.1417304111. Epub 2014 Nov 25.

26.

New tricycloalternarenes from fungus Alternaria sp.

Shi X, Wei W, Zhang WJ, Hua CP, Chen CJ, Ge HM, Tan RX, Jiao RH.

J Asian Nat Prod Res. 2015;17(2):143-8. doi: 10.1080/10286020.2014.970536. Epub 2014 Nov 17.

PMID:
25402226
27.

Oligostilbenoids with acetylcholinesterase inhibitory activity from Dipterocarpus alatus.

Chen CJ, Jiang R, Wang G, Jiao RH, Tancharoen C, Sudto K, Vajarothai S, Hannongbua S, Ge HM, Tan RX.

Planta Med. 2014 Nov;80(17):1641-6. doi: 10.1055/s-0034-1383194. Epub 2014 Oct 15.

PMID:
25317771
28.

Diaporine, a novel endophyte-derived regulator of macrophage differentiation.

Wu HC, Ge HM, Zang le Y, Bei YC, Niu ZY, Wei W, Feng XJ, Ding S, Ng SW, Shen PP, Tan RX.

Org Biomol Chem. 2014 Sep 14;12(34):6545-8. doi: 10.1039/c4ob01123f.

PMID:
25051017
29.

Cytotoxic and antimicrobial flavonoids from Cryptocarya concinna.

Huang W, Zhang WJ, Cheng YQ, Jiang R, Wei W, Chen CJ, Wang G, Jiao RH, Tan RX, Ge HM.

Planta Med. 2014 Jul;80(11):925-30. doi: 10.1055/s-0034-1368613. Epub 2014 Jul 16.

PMID:
25029174
30.

Enediyne polyketide synthases stereoselectively reduce the β-ketoacyl intermediates to β-D-hydroxyacyl intermediates in enediyne core biosynthesis.

Ge HM, Huang T, Rudolf JD, Lohman JR, Huang SX, Guo X, Shen B.

Org Lett. 2014 Aug 1;16(15):3958-61. doi: 10.1021/ol501767v. Epub 2014 Jul 14.

31.

An antibacterial metabolite from Lasiodiplodia pseudotheobromae F2.

Wei W, Jiang N, Mei YN, Chu YL, Ge HM, Song YC, Ng SW, Tan RX.

Phytochemistry. 2014 Apr;100:103-9. doi: 10.1016/j.phytochem.2014.01.003. Epub 2014 Feb 12.

PMID:
24529576
32.

Discovery of a new class of immunosuppressants from Trichothecium roseum co-inspired by cross-kingdom similarity in innate immunity and pharmacophore motif.

Zhang AH, Wang XQ, Han WB, Sun Y, Guo Y, Wu Q, Ge HM, Song YC, Ng SW, Xu Q, Tan RX.

Chem Asian J. 2013 Dec;8(12):3101-7. doi: 10.1002/asia.201300734. Epub 2013 Sep 20.

PMID:
24108442
33.

Antitumor effects of naturally occurring oligomeric resveratrol derivatives.

Qiao H, Chen X, Xu L, Wang J, Zhao G, Hou Y, Ge HM, Tan RX, Li E.

FASEB J. 2013 Nov;27(11):4561-71. doi: 10.1096/fj.13-231613. Epub 2013 Aug 7.

PMID:
23925653
34.

Polyketides from the plant endophytic fungus Cladosporium sp. IFB3lp-2.

Wuringege, Guo ZK, Wei W, Jiao RH, Yan T, Zang LY, Jiang R, Tan RX, Ge HM.

J Asian Nat Prod Res. 2013 Sep;15(9):928-33. doi: 10.1080/10286020.2013.817389. Epub 2013 Aug 5.

PMID:
23909809
35.

Efficacy, safety, and immunology of an inactivated alum-adjuvant enterovirus 71 vaccine in children in China: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.

Zhu FC, Meng FY, Li JX, Li XL, Mao QY, Tao H, Zhang YT, Yao X, Chu K, Chen QH, Hu YM, Wu X, Liu P, Zhu LY, Gao F, Jin H, Chen YJ, Dong YY, Liang YC, Shi NM, Ge HM, Liu L, Chen SG, Ai X, Zhang ZY, Ji YG, Luo FJ, Chen XQ, Zhang Y, Zhu LW, Liang ZL, Shen XL.

Lancet. 2013 Jun 8;381(9882):2024-32. doi: 10.1016/S0140-6736(13)61049-1. Epub 2013 May 29.

PMID:
23726161
36.

Cytotoxic constitutents from Cryptocarya maclurei.

Feng R, Wang T, Wei W, Tan RX, Ge HM.

Phytochemistry. 2013 Jun;90:147-53. doi: 10.1016/j.phytochem.2013.01.009. Epub 2013 Mar 13.

PMID:
23489577
37.

New flavonol and diterpenoids from the endophytic fungus Aspergillus sp. YXf3.

Yan T, Guo ZK, Jiang R, Wei W, Wang T, Guo Y, Song YC, Jiao RH, Tan RX, Ge HM.

Planta Med. 2013 Mar;79(5):348-52. doi: 10.1055/s-0032-1328260. Epub 2013 Mar 1.

PMID:
23457022
38.

Glycyrrhizic acid as the antiviral component of Glycyrrhiza uralensis Fisch. against coxsackievirus A16 and enterovirus 71 of hand foot and mouth disease.

Wang J, Chen X, Wang W, Zhang Y, Yang Z, Jin Y, Ge HM, Li E, Yang G.

J Ethnopharmacol. 2013 May 2;147(1):114-21. doi: 10.1016/j.jep.2013.02.017. Epub 2013 Feb 27.

PMID:
23454684
39.

New alkaloid from Streptomyces koyangensis residing in Odontotermes formosanus.

Bi SF, Guo ZK, Jiang N, Jiao RH, Ge HM, Tan RX.

J Asian Nat Prod Res. 2013;15(4):422-5. doi: 10.1080/10286020.2013.767246. Epub 2013 Feb 18.

PMID:
23418739
40.

Actinotetraoses I-K: tetrasaccharide metabolites produced by an insect-derived actinobacteria, Amycolatopsis sp. HCa1.

Guo ZK, Jiao RH, Dai HF, Mei WL, Tan RX, Ge HM.

Chem Biodivers. 2013 Feb;10(2):296-302. doi: 10.1002/cbdv.201200224.

PMID:
23418177
41.

Immunogenicity and safety of an enterovirus 71 vaccine in healthy Chinese children and infants: a randomised, double-blind, placebo-controlled phase 2 clinical trial.

Zhu FC, Liang ZL, Li XL, Ge HM, Meng FY, Mao QY, Zhang YT, Hu YM, Zhang ZY, Li JX, Gao F, Chen QH, Zhu QY, Chu K, Wu X, Yao X, Guo HJ, Chen XQ, Liu P, Dong YY, Li FX, Shen XL, Wang JZ.

Lancet. 2013 Mar 23;381(9871):1037-45.

PMID:
23352749
42.

Neuraminidase inhibitors from marine-derived actinomycete Streptomyces seoulensis.

Jiao RH, Xu H, Cui JT, Ge HM, Tan RX.

J Appl Microbiol. 2013 Apr;114(4):1046-53. doi: 10.1111/jam.12136. Epub 2013 Feb 8.

43.

Vaticaffinol, a resveratrol tetramer, exerts more preferable immunosuppressive activity than its precursor in vitro and in vivo through multiple aspects against activated T lymphocytes.

Feng LL, Wu XF, Liu HL, Guo WJ, Luo Q, Tao FF, Ge HM, Shen Y, Tan RX, Xu Q, Sun Y.

Toxicol Appl Pharmacol. 2013 Mar 1;267(2):167-73. doi: 10.1016/j.taap.2012.12.017. Epub 2012 Dec 29.

PMID:
23276654
44.

Angucyclines from an insect-derived actinobacterium Amycolatopsis sp. HCa1 and their cytotoxic activity.

Guo ZK, Liu SB, Jiao RH, Wang T, Tan RX, Ge HM.

Bioorg Med Chem Lett. 2012 Dec 15;22(24):7490-3. doi: 10.1016/j.bmcl.2012.10.048. Epub 2012 Oct 23.

PMID:
23131338
45.

Sesquiterpenoids from the mangrove-derived endophytic fungus Diaporthe sp.

Zang le Y, Wei W, Guo Y, Wang T, Jiao RH, Ng SW, Tan RX, Ge HM.

J Nat Prod. 2012 Oct 26;75(10):1744-9. doi: 10.1021/np3004112. Epub 2012 Sep 24.

PMID:
23006147
46.

Naphthol radical couplings determine structural features and enantiomeric excess of dalesconols in Daldinia eschscholzii.

Fang W, Ji S, Jiang N, Wang W, Zhao GY, Zhang S, Ge HM, Xu Q, Zhang AH, Zhang YL, Song YC, Zhang J, Tan RX.

Nat Commun. 2012;3:1039. doi: 10.1038/ncomms2031.

PMID:
22948821
47.

Reactogenicity and immunogenicity of an enterovirus 71 vaccine in Chinese healthy children and infants.

Zhu FC, Wang JZ, Li XL, Liang ZL, Ge HM, Meng FY, Mao QY, Zhang YT, Zhang ZY, Ji H, Gao F, Guo HJ, Zhu QY, Chu K, Wu X, Li JX, Chen QH, Chen XQ, Zhang WW, Hu YM, Li L, Li FX, Yao X, Liu P, Wang H, Shen XL.

Pediatr Infect Dis J. 2012 Nov;31(11):1158-65. doi: 10.1097/INF.0b013e31826eba74.

PMID:
22926209
48.

Thaxtomin A-deficient endophytic Streptomyces sp. enhances plant disease resistance to pathogenic Streptomyces scabies.

Lin L, Ge HM, Yan T, Qin YH, Tan RX.

Planta. 2012 Dec;236(6):1849-61. doi: 10.1007/s00425-012-1741-8. Epub 2012 Aug 25.

PMID:
22922880
49.

Protecting group-free total synthesis of (-)-lannotinidine B.

Ge HM, Zhang LD, Tan RX, Yao ZJ.

J Am Chem Soc. 2012 Aug 1;134(30):12323-5. doi: 10.1021/ja305261h. Epub 2012 Jul 17.

PMID:
22799615
50.

Polyphenolic acetylcholinesterase inhibitors from Hopea chinensis.

Yan T, Wang T, Wei W, Jiang N, Qin YH, Tan RX, Ge HM.

Planta Med. 2012 Jun;78(10):1015-9. doi: 10.1055/s-0031-1298623. Epub 2012 May 24.

PMID:
22628156

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