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Prognostic role of microRNAs in breast cancer: A systematic review.

Zografos E, Zagouri F, Kalapanida D, Zakopoulou R, Kyriazoglou A, Apostolidou K, Gazouli M, Dimopoulos MA.

Oncotarget. 2019 Dec 24;10(67):7156-7178. doi: 10.18632/oncotarget.27327. eCollection 2019 Dec 24.


ATG16L1 T300A polymorphism is associated with Crohn's disease in a Northwest Greek cohort, but ECM1 T130M and G290S polymorphisms are not associated with ulcerative colitis.

Tsianos VE, Kostoulas C, Gazouli M, Frillingos S, Georgiou I, Christodoulou DK, Katsanos KH, Tsianos EV.

Ann Gastroenterol. 2020 Jan-Feb;33(1):38-44. doi: 10.20524/aog.2019.0434. Epub 2019 Nov 21.


The Effect of Antioxidant Supplementation in Patients with Tinnitus and Normal Hearing or Hearing Loss: A Randomized, Double-Blind, Placebo Controlled Trial.

Petridou AI, Zagora ET, Petridis P, Korres GS, Gazouli M, Xenelis I, Kyrodimos E, Kontothanasi G, Kaliora AC.

Nutrients. 2019 Dec 12;11(12). pii: E3037. doi: 10.3390/nu11123037.


MiR-218 and miR-100 polymorphisms as markers of irinotecan-based chemotherapy response in metastatic colorectal cancer.

Lampropoulou DI, Aravantinos G, Laschos K, Theodosopoulos T, Papadimitriou C, Gazouli M.

Int J Colorectal Dis. 2019 Nov;34(11):1871-1877. doi: 10.1007/s00384-019-03401-3. Epub 2019 Oct 9.


Novel potential biomarkers for the diagnosis and monitoring of patients with ulcerative colitis.

Kourkoulis P, Kapizioni C, Michalopoulos G, Andreou NP, Papaconstantinou I, Karamanolis G, Gazouli M.

Eur J Gastroenterol Hepatol. 2019 Oct;31(10):1173-1183. doi: 10.1097/MEG.0000000000001490.


Association Between hsa-miR-30e Polymorphisms and Sporadic Primary Hyperparathyroidism Risk.

Mizamtsidi M, Nastos K, Palazzo F, Constantinides V, Dina R, Farenden M, Mastorakos G, Vassiliou I, Gazouli M.

In Vivo. 2019 Jul-Aug;33(4):1263-1269. doi: 10.21873/invivo.11598.


Differential genetic and functional background in inflammatory bowel disease phenotypes of a Greek population: a systems bioinformatics approach.

Gazouli M, Dovrolis N, Franke A, Spyrou GM, Sechi LA, Kolios G.

Gut Pathog. 2019 Jun 15;11:31. doi: 10.1186/s13099-019-0312-y. eCollection 2019.


Evaluation of MET T1010I and MET rs40239 single-nucleotide polymorphisms in triple-negative breast cancer: a case-control study.

Kalapanida D, Zagouri F, Gazouli M, Tsiakou A, Zografos E, Dimitrakakis C, Marinopoulos S, Giannos A, Sergentanis TN, Kastritis E, Terpos E, Dimopoulos MA.

Onco Targets Ther. 2019 May 28;12:4195-4202. doi: 10.2147/OTT.S189329. eCollection 2019.


Methylation profile of genes involved in inflammation, in the blood from pregnancies with maternal preeclampsia due to untreated gestational diabetes mellitus.

Halvatsiotis P, Tsokaki T, Chrelias C, Kassanos D, Domali E, Gazouli M, Dimitriadis G, Kalantaridou S.

Hormones (Athens). 2019 Jun;18(2):173-178. doi: 10.1007/s42000-019-00111-x. Epub 2019 Jun 1.


Incorporation of PEGylated δ-decalactone into lipid bilayers: thermodynamic study and chimeric liposomes development.

Pippa N, Skouras A, Naziris N, Biondo F, Tiboni M, Katifelis H, Gazouli M, Demetzos C, Casettari L.

J Liposome Res. 2019 Jun 14:1-9. doi: 10.1080/08982104.2019.1625377. [Epub ahead of print]


Genetic polymorphisms associated with the prevalence of retinal vein occlusion in a Greek population.

Christodoulou A, Bagli E, Gazouli M, Moschos MM, Kitsos G.

Int Ophthalmol. 2019 Nov;39(11):2637-2648. doi: 10.1007/s10792-019-01113-9. Epub 2019 May 7.


Polymorphisms of the BARX1 and ADAMTS17 Locus Genes in Individuals With Gastroesophageal Reflux Disease.

Argyrou A, Legaki E, Koutserimpas C, Gazouli M, Papaconstantinou I, Gkiokas G, Karamanolis G.

J Neurogastroenterol Motil. 2019 Jul 1;25(3):436-441. doi: 10.5056/jnm18183.


Long non-coding RNA polymorphisms and prediction of response to chemotherapy based on irinotecan in patients with metastatic colorectal cancer.

Lampropoulou DI, Aravantinos G, Katifelis H, Lazaris F, Laschos K, Theodosopoulos T, Papadimitriou C, Gazouli M.

Cancer Biomark. 2019;25(2):213-221. doi: 10.3233/CBM-182383.


DAB2IP Expression in Abdominal Aortic Aneurysm: EZH2 and mir-363-3p as Potential Mediators.

Legaki E, Klonaris C, Athanasiadis D, Patelis N, Sioziou A, Liakakos T, Gazouli M.

In Vivo. 2019 May-Jun;33(3):737-742. doi: 10.21873/invivo.11533.


Prognostic significance of miR-34 rs4938723 T > C polymorphism in triple negative breast cancer patients.

Tsiakou A, Zagouri F, Zografos E, Samelis G, Gazouli M, Kalapanida D, Giannos A, Marinopoulos S, Dimitrakakis K, Lazaris C A, Rigopoulos D, Zografos G.

Clin Biochem. 2019 Jun;68:9-14. doi: 10.1016/j.clinbiochem.2019.03.009. Epub 2019 Mar 29.


Serum Proteomic Signatures of Male Breast Cancer.

Zografos E, Anagnostopoulos AK, Papadopoulou A, Legaki E, Zagouri F, Marinos E, Tsangaris GT, Gazouli M.

Cancer Genomics Proteomics. 2019 Mar-Apr;16(2):129-137. doi: 10.21873/cgp.20118.


Contribution of ghrelin to functional gastrointestinal disorders' pathogenesis.

Koutouratsas T, Kalli T, Karamanolis G, Gazouli M.

World J Gastroenterol. 2019 Feb 7;25(5):539-551. doi: 10.3748/wjg.v25.i5.539. Review.


Germline BRCA2 K3326X and CHEK2 I157T mutations increase risk for sporadic pancreatic ductal adenocarcinoma.

Obazee O, Archibugi L, Andriulli A, Soucek P, Małecka-Panas E, Ivanauskas A, Johnson T, Gazouli M, Pausch T, Lawlor RT, Cavestro GM, Milanetto AC, Di Leo M, Pasquali C, Hegyi P, Szentesi A, Radu CE, Gheorghe C, Theodoropoulos GE, Bergmann F, Brenner H, Vodickova L, Katzke V, Campa D, Strobel O, Kaiser J, Pezzilli R, Federici F, Mohelnikova-Duchonova B, Boggi U, Lemstrova R, Johansen JS, Bojesen SE, Chen I, Jensen BV, Capurso G, Pazienza V, Dervenis C, Sperti C, Mambrini A, Hackert T, Kaaks R, Basso D, Talar-Wojnarowska R, Maiello E, Izbicki JR, Cuk K, Saum KU, Cantore M, Kupcinskas J, Palmieri O, Delle Fave G, Landi S, Salvia R, Fogar P, Vashist YK, Scarpa A, Vodicka P, Tjaden C, Iskierka-Jazdzewska E, Canzian F.

Int J Cancer. 2019 Aug 1;145(3):686-693. doi: 10.1002/ijc.32127. Epub 2019 Feb 7.


Evaluation of pre-mir-34a rs72631823 single nucleotide polymorphism in triple negative breast cancer: A case-control study.

Kalapanida D, Zagouri F, Gazouli M, Zografos E, Dimitrakakis C, Marinopoulos S, Giannos A, Sergentanis TN, Kastritis E, Terpos E, Dimopoulos MA.

Oncotarget. 2018 Dec 11;9(97):36906-36913. doi: 10.18632/oncotarget.26385. eCollection 2018 Dec 11.


Infliximab trough levels are decreasing over time in patients with inflammatory bowel disease on maintenance treatment with infliximab.

Orfanoudaki E, Gazouli M, Foteinogiannopoulou K, Theodoraki E, Legaki E, Romanos I, Mouzas I, Koutroubakis IE.

Eur J Gastroenterol Hepatol. 2019 Feb;31(2):187-191. doi: 10.1097/MEG.0000000000001332.


Association between genetic polymorphisms in long non-coding RNAs and pancreatic cancer risk.

Moschovis D, Vasilaki E, Tzouvala M, Karamanolis G, Katifelis H, Legaki E, Vezakis A, Aravantinos G, Gazouli M.

Cancer Biomark. 2019;24(1):117-123. doi: 10.3233/CBM-181959.


Ag/Au bimetallic nanoparticles induce apoptosis in human cancer cell lines via P53, CASPASE-3 and BAX/BCL-2 pathways.

Katifelis H, Lyberopoulou A, Mukha I, Vityuk N, Grodzyuk G, Theodoropoulos GE, Efstathopoulos EP, Gazouli M.

Artif Cells Nanomed Biotechnol. 2018;46(sup3):S389-S398. doi: 10.1080/21691401.2018.1495645. Epub 2018 Oct 29.


Risk factors for gastroesophageal reflux disease and analysis of genetic contributors.

Argyrou A, Legaki E, Koutserimpas C, Gazouli M, Papaconstantinou I, Gkiokas G, Karamanolis G.

World J Clin Cases. 2018 Aug 16;6(8):176-182. doi: 10.12998/wjcc.v6.i8.176. Review.


"Extracellular matrix remodelling in the liver of rats subjected to dietary choline deprivation and/or thioacetamide administration".

Al-Humadi H, Alhumadi A, Al-Saigh R, Strilakou A, Lazaris AC, Gazouli M, Liapi C.

Clin Exp Pharmacol Physiol. 2018 Dec;45(12):1245-1256. doi: 10.1111/1440-1681.13013. Epub 2018 Aug 22.


Successful use of adipose-derived mesenchymal stem cells to correct a male breast affected by Poland Syndrome: a case report.

Christopoulos A, Ligoudistianou C, Bethanis P, Gazouli M.

J Surg Case Rep. 2018 Jul 9;2018(7):rjy151. doi: 10.1093/jscr/rjy151. eCollection 2018 Jul.


Common genetic variants associated with pancreatic adenocarcinoma may also modify risk of pancreatic neuroendocrine neoplasms.

Obazee O, Capurso G, Tavano F, Archibugi L, De Bonis A, Greenhalf W, Key T, Pasquali C, Milanetto AC, Hackert T, Fogar P, Lico V, Dervenis C, Lawlor RT, Landoni L, Gazouli M, Zambon CF, Funel N, Strobel O, Jamroziak K, Cantu C, Malecka-Panas E, Landi S, Neoptolemos JP, Basso D, Talar-Wojnarowska R, Rinzivillo M, Andriulli A, Canzian F, Campa D.

Carcinogenesis. 2018 Jul 3;39(7):969. doi: 10.1093/carcin/bgy067. No abstract available.


Interleukin 15 concentrations in follicular fluid and their effect on oocyte maturation in subfertile women undergoing intracytoplasmic sperm injection.

Spanou S, Kalogiannis D, Zapanti E, Gazouli M, Sfontouris IA, Siristatidis C, Mastorakos G.

J Assist Reprod Genet. 2018 Jun;35(6):1019-1025. doi: 10.1007/s10815-018-1170-0. Epub 2018 Apr 4.


Correlation of polymorphisms in long non-coding RNAs with the pathogenesis of inflammatory bowel diseases.

Zacharopoulou E, Ioakeim S, Tzouvala M, Karamanolis G, Vezakis A, Gazouli M.

Dig Liver Dis. 2018 Jun;50(6):624-626. doi: 10.1016/j.dld.2018.03.008. Epub 2018 Mar 13. No abstract available.


Expression of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Human Epicardial and Intramyocardial Coronary Arteries of Male Patients Undergoing Coronary Artery Bypass Grafting.

Synetos A, Karanasos A, Spyropoulos S, Gazouli M, Latsios G, Toutouzas K, Perrea D, Tousoulis D, Chloroyiannis IA.

Cardiology. 2018;139(4):203-207. doi: 10.1159/000486634. Epub 2018 Feb 15.


Gallium-68 Labeled Iron Oxide Nanoparticles Coated with 2,3-Dicarboxypropane-1,1-diphosphonic Acid as a Potential PET/MR Imaging Agent: A Proof-of-Concept Study.

Karageorgou MA, Vranješ-Djurić S, Radović M, Lyberopoulou A, Antić B, Rouchota M, Gazouli M, Loudos G, Xanthopoulos S, Sideratou Z, Stamopoulos D, Bouziotis P, Tsoukalas C.

Contrast Media Mol Imaging. 2017 Dec 28;2017:6951240. doi: 10.1155/2017/6951240. eCollection 2017.


Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer.

Klein AP, Wolpin BM, Risch HA, Stolzenberg-Solomon RZ, Mocci E, Zhang M, Canzian F, Childs EJ, Hoskins JW, Jermusyk A, Zhong J, Chen F, Albanes D, Andreotti G, Arslan AA, Babic A, Bamlet WR, Beane-Freeman L, Berndt SI, Blackford A, Borges M, Borgida A, Bracci PM, Brais L, Brennan P, Brenner H, Bueno-de-Mesquita B, Buring J, Campa D, Capurso G, Cavestro GM, Chaffee KG, Chung CC, Cleary S, Cotterchio M, Dijk F, Duell EJ, Foretova L, Fuchs C, Funel N, Gallinger S, M Gaziano JM, Gazouli M, Giles GG, Giovannucci E, Goggins M, Goodman GE, Goodman PJ, Hackert T, Haiman C, Hartge P, Hasan M, Hegyi P, Helzlsouer KJ, Herman J, Holcatova I, Holly EA, Hoover R, Hung RJ, Jacobs EJ, Jamroziak K, Janout V, Kaaks R, Khaw KT, Klein EA, Kogevinas M, Kooperberg C, Kulke MH, Kupcinskas J, Kurtz RJ, Laheru D, Landi S, Lawlor RT, Lee IM, LeMarchand L, Lu L, Malats N, Mambrini A, Mannisto S, Milne RL, Mohelníková-Duchoňová B, Neale RE, Neoptolemos JP, Oberg AL, Olson SH, Orlow I, Pasquali C, Patel AV, Peters U, Pezzilli R, Porta M, Real FX, Rothman N, Scelo G, Sesso HD, Severi G, Shu XO, Silverman D, Smith JP, Soucek P, Sund M, Talar-Wojnarowska R, Tavano F, Thornquist MD, Tobias GS, Van Den Eeden SK, Vashist Y, Visvanathan K, Vodicka P, Wactawski-Wende J, Wang Z, Wentzensen N, White E, Yu H, Yu K, Zeleniuch-Jacquotte A, Zheng W, Kraft P, Li D, Chanock S, Obazee O, Petersen GM, Amundadottir LT.

Nat Commun. 2018 Feb 8;9(1):556. doi: 10.1038/s41467-018-02942-5.


Diagnosis, management, histology and genetics of sporadic primary hyperparathyroidism: old knowledge with new tricks.

Mizamtsidi M, Nastos C, Mastorakos G, Dina R, Vassiliou I, Gazouli M, Palazzo F.

Endocr Connect. 2018 Feb;7(2):R56-R68. doi: 10.1530/EC-17-0283. Epub 2018 Jan 12. Review.


Common genetic variants associated with pancreatic adenocarcinoma may also modify risk of pancreatic neuroendocrine neoplasms.

Obazee O, Capurso G, Tavano F, Archibugi L, De Bonis A, Greenhalf W, Key T, Pasquali C, Milanetto AC, Hackert T, Fogar P, Liço V, Dervenis C, Lawlor RT, Landoni L, Gazouli M, Zambon CF, Funel N, Strobel O, Jamroziak K, Cantù C, Malecka-Panas E, Landi S, Neoptolemos JP, Basso D, Talar-Wojnarowska R, Rinzivillo M, Andriulli A, Canzian F, Campa D.

Carcinogenesis. 2018 Mar 8;39(3):360-367. doi: 10.1093/carcin/bgx150. Erratum in: Carcinogenesis. 2018 Jul 3;39(7):969.


Correction: Human alpha defensin 5 is a candidate biomarker to delineate inflammatory bowel disease.

Williams AD, Korolkova OY, Sakwe AM, Geiger TM, James SD, Muldoon RL, Herline AJ, Goodwin JS, Izban MG, Washington MK, Smoot DT, Ballard BR, Gazouli M, M'Koma AE.

PLoS One. 2017 Dec 6;12(12):e0189551. doi: 10.1371/journal.pone.0189551. eCollection 2017.


Association of miR-146 rs2910164, miR-196a rs11614913, miR-221 rs113054794 and miR-224 rs188519172 polymorphisms with anti-TNF treatment response in a Greek population with Crohn's disease.

Papaconstantinou I, Kapizioni C, Legaki E, Xourgia E, Karamanolis G, Gklavas A, Gazouli M.

World J Gastrointest Pharmacol Ther. 2017 Nov 6;8(4):193-200. doi: 10.4292/wjgpt.v8.i4.193.


Long non-coding RNA in pancreatic adenocarcinoma and pancreatic neuroendocrine tumors.

Moschovis D, Gazouli M, Tzouvala M, Vezakis A, Karamanolis G.

Ann Gastroenterol. 2017;30(6):622-628. doi: 10.20524/aog.2017.0185. Epub 2017 Aug 4. Review.


Do pancreatic cancer and chronic pancreatitis share the same genetic risk factors? A PANcreatic Disease ReseArch (PANDoRA) consortium investigation.

Campa D, Pastore M, Capurso G, Hackert T, Di Leo M, Izbicki JR, Khaw KT, Gioffreda D, Kupcinskas J, Pasquali C, Macinga P, Kaaks R, Stigliano S, Peeters PH, Key TJ, Talar-Wojnarowska R, Vodicka P, Valente R, Vashist YK, Salvia R, Papaconstantinou I, Shimizu Y, Valsuani C, Zambon CF, Gazouli M, Valantiene I, Niesen W, Mohelnikova-Duchonova B, Hara K, Soucek P, Malecka-Panas E, Bueno-de-Mesquita HBA, Johnson T, Brenner H, Tavano F, Fogar P, Ito H, Sperti C, Butterbach K, Latiano A, Andriulli A, Cavestro GM, Busch ORC, Dijk F, Greenhalf W, Matsuo K, Lombardo C, Strobel O, König AK, Cuk K, Strothmann H, Katzke V, Cantore M, Mambrini A, Oliverius M, Pezzilli R, Landi S, Canzian F.

Int J Cancer. 2018 Jan 15;142(2):290-296. doi: 10.1002/ijc.31047. Epub 2017 Oct 16.


BAX and BCL2 Gene Polymorphisms in Rhegmatogenous Retinal Detachment.

Moschos MM, Chatziralli I, Brouzas D, Gazouli M.

Ophthalmic Res. 2017;58(4):227-230. doi: 10.1159/000479700. Epub 2017 Sep 7.


The contribution of long non-coding RNAs in Inflammatory Bowel Diseases.

Zacharopoulou E, Gazouli M, Tzouvala M, Vezakis A, Karamanolis G.

Dig Liver Dis. 2017 Oct;49(10):1067-1072. doi: 10.1016/j.dld.2017.08.003. Epub 2017 Aug 9. Review.


Human alpha defensin 5 is a candidate biomarker to delineate inflammatory bowel disease.

Williams AD, Korolkova OY, Sakwe AM, Geiger TM, James SD, Muldoon RL, Herline AJ, Goodwin JS, Izban MG, Washington MK, Smoot DT, Ballard BR, Gazouli M, M'Koma AE.

PLoS One. 2017 Aug 17;12(8):e0179710. doi: 10.1371/journal.pone.0179710. eCollection 2017. Erratum in: PLoS One. 2017 Dec 6;12 (12 ):e0189551.


Identification of serum proteome signature of irritable bowel syndrome: Potential utility of the tool for early diagnosis and patient's stratification.

Tsigaridas A, Anagnostopoulos AK, Papadopoulou A, Ioakeim S, Vaiopoulou A, Papanikolaou IS, Viazis N, Karamanolis G, Mantzaris GJ, Tsangaris GT, Gazouli M.

J Proteomics. 2018 Sep 30;188:167-172. doi: 10.1016/j.jprot.2017.07.019. Epub 2017 Jul 28.


Prognostic and predictive factors in patients with metastatic or recurrent cervical cancer treated with platinum-based chemotherapy.

Karageorgopoulou S, Kostakis ID, Gazouli M, Markaki S, Papadimitriou M, Bournakis E, Dimopoulos MA, Papadimitriou CA.

BMC Cancer. 2017 Jun 28;17(1):451. doi: 10.1186/s12885-017-3435-x.


Molecular Proteomic Characterization of a Pediatric Medulloblastoma Xenograft.

Tsangaris GT, Dimas K, Malamou A, Katsafadou A, Papathanasiou C, Stravopodis DJ, Vorgias CE, Gazouli M, Anagnostopoulos AK.

Cancer Genomics Proteomics. 2017 Jul-Aug;14(4):267-275.


Abnormal DNA methylation as a cell-free circulating DNA biomarker for colorectal cancer detection: A review of literature.

Galanopoulos M, Tsoukalas N, Papanikolaou IS, Tolia M, Gazouli M, Mantzaris GJ.

World J Gastrointest Oncol. 2017 Apr 15;9(4):142-152. doi: 10.4251/wjgo.v9.i4.142. Review.


Receptor of Advanced Glycation End Products Gene Polymorphism and Primary Open-Angle Glaucoma.

Moschos MM, Chatziralli I, Sioziou A, Gazouli M.

Ophthalmic Res. 2017;58(2):81-84. doi: 10.1159/000464448. Epub 2017 Apr 12.


Proteomics and irritable bowel syndrome.

Tsigaridas A, Papanikolaou IS, Vaiopoulou A, Anagnostopoulos AK, Viazis N, Karamanolis G, Karamanolis DG, Tsangaris GT, Mantzaris GJ, Gazouli M.

Expert Rev Proteomics. 2017 May;14(5):461-468. doi: 10.1080/14789450.2017.1317600. Epub 2017 Apr 17. Review.


The Q192R polymorphism of the paraoxonase-1 (PON1) gene is associated with susceptibility to gestational diabetes mellitus in the Greek population.

Pappa KI, Gazouli M, Anastasiou E, Loutradis D, Anagnou NP.

Gynecol Endocrinol. 2017 Aug;33(8):617-620. doi: 10.1080/09513590.2017.1302419. Epub 2017 Mar 28.


Identification of Methylation Profiles of Cancer-related Genes in Circulating Tumor Cells Population.

Lyberopoulou A, Galanopoulos M, Aravantinos G, Theodoropoulos GE, Marinos E, Efstathopoulos EP, Gazouli M.

Anticancer Res. 2017 Mar;37(3):1105-1112.


SLC22A3 polymorphisms do not modify pancreatic cancer risk, but may influence overall patient survival.

Mohelnikova-Duchonova B, Strouhal O, Hughes DJ, Holcatova I, Oliverius M, Kala Z, Campa D, Rizzato C, Canzian F, Pezzilli R, Talar-Wojnarowska R, Malecka-Panas E, Sperti C, Federico Zambon C, Pedrazzoli S, Fogar P, Milanetto AC, Capurso G, Delle Fave G, Valente R, Gazouli M, Malleo G, Teresa Lawlor R, Strobel O, Hackert T, Giese N, Vodicka P, Vodickova L, Landi S, Tavano F, Gioffreda D, Piepoli A, Pazienza V, Mambrini A, Pedata M, Cantore M, Bambi F, Ermini S, Funel N, Lemstrova R, Soucek P.

Sci Rep. 2017 Mar 8;7:43812. doi: 10.1038/srep43812.


Comparative Study of Mutations in Single Nucleotide Polymorphism Loci of KRAS and BRAF Genes in Patients Who Underwent Screening Colonoscopy, With and Without Premalignant Intestinal Polyps.

Galanopoulos M, Papanikolaou IS, Zografos E, Viazis N, Papatheodoridis G, Karamanolis D, Marinos E, Mantzaris GJ, Gazouli M.

Anticancer Res. 2017 Feb;37(2):651-657.


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