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Items: 25

1.

A model for determining an effective in vivo dose of transplanted islets based on in vitro insulin secretion.

Holdcraft RW, Dumpala PR, Smith BH, Gazda LS.

Xenotransplantation. 2018 Jul 28:e12443. doi: 10.1111/xen.12443. [Epub ahead of print]

PMID:
30054944
2.
3.

A comprehensive microbiological safety approach for agarose encapsulated porcine islets intended for clinical trials.

Gazda LS, Collins J, Lovatt A, Holdcraft RW, Morin MJ, Galbraith D, Graham M, Laramore MA, Maclean C, Black J, Milne EW, Marthaler DG, Vinerean HV, Michalak MM, Hoffer D, Richter S, Hall RD, Smith BH.

Xenotransplantation. 2016 Nov;23(6):444-463. doi: 10.1111/xen.12277. Epub 2016 Nov 11.

PMID:
27862363
4.

Optimizing Porcine Islet Isolation to Markedly Reduce Enzyme Consumption Without Sacrificing Islet Yield or Function.

Holdcraft RW, Green ML, Breite AG, Circle L, Meyer ED, Adkins H, Harbeck SG, Smith BH, Gazda LS.

Transplant Direct. 2016 Jun 6;2(7):e86. eCollection 2016 Jul.

5.

First-in-Human Phase 1 Trial of Agarose Beads Containing Murine RENCA Cells in Advanced Solid Tumors.

Smith BH, Parikh T, Andrada ZP, Fahey TJ, Berman N, Wiles M, Nazarian A, Thomas J, Arreglado A, Akahoho E, Wolf DJ, Levine DM, Parker TS, Gazda LS, Ocean AJ.

Cancer Growth Metastasis. 2016 Aug 2;9:9-20. doi: 10.4137/CGM.S39442. eCollection 2016.

6.

Retention of gene expression in porcine islets after agarose encapsulation and long-term culture.

Dumpala PR, Holdcraft RW, Martis PC, Laramore MA, Parker TS, Levine DM, Smith BH, Gazda LS.

Biochem Biophys Res Commun. 2016 Aug 5;476(4):580-585. doi: 10.1016/j.bbrc.2016.05.165. Epub 2016 May 31.

PMID:
27261433
7.

First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--Chapter 3: Porcine islet product manufacturing and release testing criteria.

Rayat GR, Gazda LS, Hawthorne WJ, Hering BJ, Hosking P, Matsumoto S, Rajotte RV.

Xenotransplantation. 2016 Jan-Feb;23(1):38-45. doi: 10.1111/xen.12225. Epub 2016 Feb 29.

PMID:
26923763
8.

No evidence of viral transmission following long-term implantation of agarose encapsulated porcine islets in diabetic dogs.

Gazda LS, Vinerean HV, Laramore MA, Hall RD, Carraway JW, Smith BH.

J Diabetes Res. 2014;2014:727483. doi: 10.1155/2014/727483. Epub 2014 Jun 5.

9.

Pravastatin improves glucose regulation and biocompatibility of agarose encapsulated porcine islets following transplantation into pancreatectomized dogs.

Gazda LS, Vinerean HV, Laramore MA, Hall RD, Carraway JW, Smith BH.

J Diabetes Res. 2014;2014:405362. doi: 10.1155/2014/405362. Epub 2014 May 19.

10.

Treatment of agarose-agarose RENCA macrobeads with docetaxel selects for OCT4(+) cells with tumor-initiating capability.

Gazda LS, Martis PC, Laramore MA, Bautista MA, Dudley A, Vinerean HV, Smith BH.

Cancer Biol Ther. 2013 Dec;14(12):1147-57. doi: 10.4161/cbt.26455. Epub 2013 Sep 12.

11.

Enhancement of in vitro and in vivo function of agarose-encapsulated porcine islets by changes in the islet microenvironment.

Holdcraft RW, Gazda LS, Circle L, Adkins H, Harbeck SG, Meyer ED, Bautista MA, Martis PC, Laramore MA, Vinerean HV, Hall RD, Smith BH.

Cell Transplant. 2014;23(8):929-44. doi: 10.3727/096368913X667033. Epub 2013 Apr 29.

PMID:
23635430
13.

Three-dimensional culture of mouse renal carcinoma cells in agarose macrobeads selects for a subpopulation of cells with cancer stem cell or cancer progenitor properties.

Smith BH, Gazda LS, Conn BL, Jain K, Asina S, Levine DM, Parker TS, Laramore MA, Martis PC, Vinerean HV, David EM, Qiu S, Cordon-Cardo C, Hall RD, Gordon BR, Diehl CH, Stenzel KH, Rubin AL.

Cancer Res. 2011 Feb 1;71(3):716-24. doi: 10.1158/0008-5472.CAN-10-2254. Epub 2011 Jan 24.

14.

Hydrophilic agarose macrobead cultures select for outgrowth of carcinoma cell populations that can restrict tumor growth.

Smith BH, Gazda LS, Conn BL, Jain K, Asina S, Levine DM, Parker TS, Laramore MA, Martis PC, Vinerean HV, David EM, Qiu S, North AJ, Couto CG, Post GS, Waters DJ, Cordon-Cardo C, Hall RD, Gordon BR, Diehl CH, Stenzel KH, Rubin AL.

Cancer Res. 2011 Feb 1;71(3):725-35. doi: 10.1158/0008-5472.CAN-10-2258. Epub 2011 Jan 24.

15.

Improved glucose regulation on a low carbohydrate diet in diabetic rats transplanted with macroencapsulated porcine islets.

Vinerean HV, Gazda LS, Hall RD, Rubin AL, Smith BH.

Cell Transplant. 2008;17(5):567-75.

PMID:
18714676
16.

Encapsulation of porcine islets permits extended culture time and insulin independence in spontaneously diabetic BB rats.

Gazda LS, Vinerean HV, Laramore MA, Diehl CH, Hall RD, Rubin AL, Smith BH.

Cell Transplant. 2007;16(6):609-20.

PMID:
17912952
17.

The use of pancreas biopsy scoring provides reliable porcine islet yields while encapsulation permits the determination of microbiological safety.

Gazda LS, Adkins H, Bailie JA, Byrd W, Circle L, Conn B, Diehl CH, Hall RD, Rubin AL, Smith BH.

Cell Transplant. 2005;14(7):427-39.

PMID:
16285251
18.

Stressor exposure produces long-term reductions in antigen-specific T and B cell responses.

Gazda LS, Smith T, Watkins LR, Maier SF, Fleshner M.

Stress. 2003 Dec;6(4):259-67.

PMID:
14660058
19.

Sciatic inflammatory neuritis (SIN): behavioral allodynia is paralleled by peri-sciatic proinflammatory cytokine and superoxide production.

Gazda LS, Milligan ED, Hansen MK, Twining CM, Poulos NM, Chacur M, O'Connor KA, Armstrong C, Maier SF, Watkins LR, Myers RR.

J Peripher Nerv Syst. 2001 Sep;6(3):111-29.

PMID:
11817330
20.

A new model of sciatic inflammatory neuritis (SIN): induction of unilateral and bilateral mechanical allodynia following acute unilateral peri-sciatic immune activation in rats.

Chacur M, Milligan ED, Gazda LS, Armstrong C, Wang H, Tracey KJ, Maier SF, Watkins LR.

Pain. 2001 Dec;94(3):231-44.

PMID:
11731060
21.

Diabetes results from a late change in the autoimmune response of NOD mice.

Gazda LS, Charlton B, Lafferty KJ.

J Autoimmun. 1997 Jun;10(3):261-70.

PMID:
9218753
22.

Tolerance: a case of self/not-self discrimination maintained by clonal deletion?

Lafferty KJ, Gazda LS.

Hum Immunol. 1997 Feb;52(2):119-26. Review.

PMID:
9077560
23.

Regulation of autoimmune diabetes: characteristics of non-islet-antigen specific therapies.

Gazda LS, Baxter AG, Lafferty KJ.

Immunol Cell Biol. 1996 Oct;74(5):401-7.

PMID:
8912002
24.

Autoimmune diabetes: caught in the causality trap?

Gazda LS, Gilchrist KA, Lafferty KJ.

Immunol Cell Biol. 1995 Dec;73(6):549-51.

PMID:
8713477
25.

Circulating lymphocyte populations and autoantibodies in non-obese diabetic (NOD) mice: a longitudinal study.

Pontesilli O, Carotenuto P, Gazda LS, Pratt PF, Prowse SJ.

Clin Exp Immunol. 1987 Oct;70(1):84-93.

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