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Items: 1 to 50 of 106

1.

Vitamin D Modulates the Response of Bronchial Epithelial Cells Exposed to Cigarette Smoke Extract.

Mathyssen C, Serré J, Sacreas A, Everaerts S, Maes K, Verleden S, Verlinden L, Verstuyf A, Pilette C, Gayan-Ramirez G, Vanaudenaerde B, Janssens W.

Nutrients. 2019 Sep 6;11(9). pii: E2138. doi: 10.3390/nu11092138.

2.

Airway morphometry in COPD with bronchiectasis: a view on all airway generations.

Everaerts S, McDonough JE, Verleden SE, Josipovic I, Boone M, Dubbeldam A, Mathyssen C, Serré J, Dupont LJ, Gayan-Ramirez G, Verschakelen J, Hogg JC, Verleden GM, Vanaudenaerde BM, Janssens W.

Eur Respir J. 2019 Nov 7;54(5). pii: 1802166. doi: 10.1183/13993003.02166-2018. Print 2019 Nov.

PMID:
31467117
3.

Oxidants Regulated Diaphragm Proteolysis during Mechanical Ventilation in Rats.

Moroz N, Maes K, Leduc-Gaudet JP, Goldberg P, Petrof BJ, Mayaki D, Vassilakopoulos T, Rassier D, Gayan-Ramirez G, Hussain SN.

Anesthesiology. 2019 Sep;131(3):605-618. doi: 10.1097/ALN.0000000000002837.

PMID:
31408447
4.

Targeting Vitamin D Deficiency to Limit Exacerbations in Respiratory Diseases: Utopia or Strategy With Potential?

Maes K, Serré J, Mathyssen C, Janssens W, Gayan-Ramirez G.

Calcif Tissue Int. 2019 Jul 26. doi: 10.1007/s00223-019-00591-4. [Epub ahead of print] Review.

PMID:
31350569
5.

Data on inflammatory cytokines and pathways involved in clearance of Nontypeable Haemophilus influenzae from the lungs during cigarette smoking and vitamin D deficiency.

Serré J, Mathyssen C, Ajime TT, Korf H, Maes K, Heulens N, Gysemans C, Mathieu C, Vanaudenaerde B, Janssens W, Gayan-Ramirez G.

Data Brief. 2018 Dec 18;22:703-708. doi: 10.1016/j.dib.2018.12.048. eCollection 2019 Feb.

6.

Airway infection with Nontypeable Haemophilus influenzae is more rapidly eradicated in vitamin D deficient mice.

Serré J, Mathyssen C, Ajime TT, Korf H, Maes K, Heulens N, Gysemans C, Mathieu C, Vanaudenaerde B, Janssens W, Gayan-Ramirez G.

J Steroid Biochem Mol Biol. 2019 Mar;187:42-51. doi: 10.1016/j.jsbmb.2018.10.021. Epub 2018 Nov 3.

PMID:
30399417
7.

Increased IgA Expression in Lung Lymphoid Follicles in Severe Chronic Obstructive Pulmonary Disease.

Ladjemi MZ, Martin C, Lecocq M, Detry B, Nana FA, Moulin C, Weynand B, Fregimilicka C, Bouzin C, Thurion P, Carlier F, Serré J, Gayan-Ramirez G, Delos M, Ocak S, Burgel PR, Pilette C.

Am J Respir Crit Care Med. 2019 Mar 1;199(5):592-602. doi: 10.1164/rccm.201802-0352OC.

PMID:
30339768
8.

Effect of Long-Term Polytrauma on Ventilator-Induced Diaphragmatic Dysfunction in a Piglet Model.

Breuer T, Bruells CS, Horst K, Thiele C, Hildebrand F, Linnartz S, Siegberg T, Frank N, Gayan-Ramirez G, Martin L, Ostareck DH, Marx G, Simon TP.

Shock. 2019 Oct;52(4):443-448. doi: 10.1097/SHK.0000000000001272.

PMID:
30300316
9.

Prolonged mechanical ventilation worsens sepsis-induced diaphragmatic dysfunction in the rat.

Le Dinh M, Carreira S, Obert J, Gayan-Ramirez G, Riou B, Beuvin M, Similowski T, Coirault C, Demoule A.

PLoS One. 2018 Aug 1;13(8):e0200429. doi: 10.1371/journal.pone.0200429. eCollection 2018.

10.

Providing direction improves function: Comparison of a radial pore-orientated acellular collagen scaffold to clinical alternatives in a surgically induced rabbit diaphragmatic tissue defect model.

Eastwood MP, Daamen WF, Joyeux L, Pranpanus S, Rynkevic R, Hympanova L, Pot MW, Hof DJ, Gayan-Ramirez G, van Kuppevelt TH, Verbeken E, Deprest J.

J Tissue Eng Regen Med. 2018 Nov;12(11):2138-2150. doi: 10.1002/term.2734. Epub 2018 Sep 12.

PMID:
30055525
11.

Relevance of nutritional support and early rehabilitation in hospitalized patients with COPD.

Gayan-Ramirez G.

J Thorac Dis. 2018 May;10(Suppl 12):S1400-S1414. doi: 10.21037/jtd.2018.03.167. Review.

12.

The aging lung: tissue telomere shortening in health and disease.

Everaerts S, Lammertyn EJ, Martens DS, De Sadeleer LJ, Maes K, van Batenburg AA, Goldschmeding R, van Moorsel CHM, Dupont LJ, Wuyts WA, Vos R, Gayan-Ramirez G, Kaminski N, Hogg JC, Janssens W, Verleden GM, Nawrot TS, Verleden SE, McDonough JE, Vanaudenaerde BM.

Respir Res. 2018 May 11;19(1):95. doi: 10.1186/s12931-018-0794-z.

13.

Dexmedetomidine Impairs Diaphragm Function and Increases Oxidative Stress but Does Not Aggravate Diaphragmatic Atrophy in Mechanically Ventilated Rats.

Breuer T, Bleilevens C, Rossaint R, Marx G, Gehrenkemper J, Dierksen H, Delpierre A, Weis J, Gayan-Ramirez G, Bruells CS.

Anesthesiology. 2018 Apr;128(4):784-795. doi: 10.1097/ALN.0000000000002081.

PMID:
29346133
14.

Vitamin D supplementation in respiratory diseases: evidence from randomized controlled trials.

Mathyssen C, Gayan-Ramirez G, Bouillon R, Janssens W.

Pol Arch Intern Med. 2017 Nov 30;127(11):775-784. doi: 10.20452/pamw.4134. Epub 2017 Nov 2. Review.

15.

A growing animal model for neonatal repair of large diaphragmatic defects to evaluate patch function and outcome.

Eastwood MP, Joyeux L, Pranpanus S, Van der Merwe J, Verbeken E, De Vleeschauwer S, Gayan-Ramirez G, Deprest J.

PLoS One. 2017 Mar 30;12(3):e0174332. doi: 10.1371/journal.pone.0174332. eCollection 2017.

16.

Kinetics of ventilation-induced changes in diaphragmatic metabolism by bilateral phrenic pacing in a piglet model.

Breuer T, Hatam N, Grabiger B, Marx G, Behnke BJ, Weis J, Kopp R, Gayan-Ramirez G, Zoremba N, Bruells CS.

Sci Rep. 2016 Oct 19;6:35725. doi: 10.1038/srep35725.

17.

Influence of weaning methods on the diaphragm after mechanical ventilation in a rat model.

Bruells CS, Breuer T, Maes K, Bergs I, Bleilevens C, Marx G, Weis J, Gayan-Ramirez G, Rossaint R.

BMC Pulm Med. 2016 Aug 24;16(1):127. doi: 10.1186/s12890-016-0285-2.

18.

1,25-Dihydroxyvitamin D Modulates Antibacterial and Inflammatory Response in Human Cigarette Smoke-Exposed Macrophages.

Heulens N, Korf H, Mathyssen C, Everaerts S, De Smidt E, Dooms C, Yserbyt J, Gysemans C, Gayan-Ramirez G, Mathieu C, Janssens W.

PLoS One. 2016 Aug 11;11(8):e0160482. doi: 10.1371/journal.pone.0160482. eCollection 2016.

19.

The effects of smoking on whisker movements: A quantitative measure of exploratory behaviour in rodents.

Grant RA, Cielen N, Maes K, Heulens N, Galli GL, Janssens W, Gayan-Ramirez G, Degens H.

Behav Processes. 2016 Jul;128:17-23. doi: 10.1016/j.beproc.2016.03.021. Epub 2016 Apr 1.

PMID:
27045697
20.

Vitamin D deficiency impairs skeletal muscle function in a smoking mouse model.

Cielen N, Heulens N, Maes K, Carmeliet G, Mathieu C, Janssens W, Gayan-Ramirez G.

J Endocrinol. 2016 May;229(2):97-108. doi: 10.1530/JOE-15-0491. Epub 2016 Feb 23.

21.

Interaction between Physical Activity and Smoking on Lung, Muscle, and Bone in Mice.

Cielen N, Maes K, Heulens N, Troosters T, Carmeliet G, Janssens W, Gayan-Ramirez GN.

Am J Respir Cell Mol Biol. 2016 May;54(5):674-82. doi: 10.1165/rcmb.2015-0181OC.

PMID:
26448063
22.

Vitamin D deficiency exacerbates COPD-like characteristics in the lungs of cigarette smoke-exposed mice.

Heulens N, Korf H, Cielen N, De Smidt E, Maes K, Gysemans C, Verbeken E, Gayan-Ramirez G, Mathieu C, Janssens W.

Respir Res. 2015 Sep 16;16:110. doi: 10.1186/s12931-015-0271-x.

23.

Sevoflurane exposure prevents diaphragmatic oxidative stress during mechanical ventilation but reduces force and affects protein metabolism even during spontaneous breathing in a rat model.

Breuer T, Maes K, Rossaint R, Marx G, Scheers H, Bergs I, Bleilevens C, Gayan-Ramirez G, Bruells CS.

Anesth Analg. 2015 Jul;121(1):73-80. doi: 10.1213/ANE.0000000000000736.

PMID:
25851179
24.

Smoking-induced skeletal muscle dysfunction: from evidence to mechanisms.

Degens H, Gayan-Ramirez G, van Hees HW.

Am J Respir Crit Care Med. 2015 Mar 15;191(6):620-5. doi: 10.1164/rccm.201410-1830PP. Review.

PMID:
25581779
25.

Effects of controlled mechanical ventilation on sepsis-induced diaphragm dysfunction in rats.

Maes K, Stamiris A, Thomas D, Cielen N, Smuder A, Powers SK, Leite FS, Hermans G, Decramer M, Hussain SN, Gayan-Ramirez G.

Crit Care Med. 2014 Dec;42(12):e772-82. doi: 10.1097/CCM.0000000000000685.

PMID:
25402297
26.

An official American Thoracic Society/European Respiratory Society statement: update on limb muscle dysfunction in chronic obstructive pulmonary disease.

Maltais F, Decramer M, Casaburi R, Barreiro E, Burelle Y, Debigaré R, Dekhuijzen PN, Franssen F, Gayan-Ramirez G, Gea J, Gosker HR, Gosselink R, Hayot M, Hussain SN, Janssens W, Polkey MI, Roca J, Saey D, Schols AM, Spruit MA, Steiner M, Taivassalo T, Troosters T, Vogiatzis I, Wagner PD; ATS/ERS Ad Hoc Committee on Limb Muscle Dysfunction in COPD.

Am J Respir Crit Care Med. 2014 May 1;189(9):e15-62. doi: 10.1164/rccm.201402-0373ST. Review.

27.

Musculoskeletal disorders in chronic obstructive pulmonary disease.

Cielen N, Maes K, Gayan-Ramirez G.

Biomed Res Int. 2014;2014:965764. doi: 10.1155/2014/965764. Epub 2014 Mar 25. Review.

28.

A satellite cell-specific knockout of the androgen receptor reveals myostatin as a direct androgen target in skeletal muscle.

Dubois V, Laurent MR, Sinnesael M, Cielen N, Helsen C, Clinckemalie L, Spans L, Gayan-Ramirez G, Deldicque L, Hespel P, Carmeliet G, Vanderschueren D, Claessens F.

FASEB J. 2014 Jul;28(7):2979-94. doi: 10.1096/fj.14-249748. Epub 2014 Mar 26.

PMID:
24671706
29.

COPD awareness survey: do Belgian pulmonary physicians comply with the GOLD guidelines 2010?

Decramer M, Brusselle G, Buffels J, Corhay JL, De Backer W, Degryse JM, Janssens W, Marchand E, Van den Brande P, Vincken W, Gayan-Ramirez G, Van Craenendonck V, Vandenberghe H, De Vuyst P; COPD Working Group.

Acta Clin Belg. 2013 Sep-Oct;68(5):325-40.

PMID:
24579239
30.

Sedation using propofol induces similar diaphragm dysfunction and atrophy during spontaneous breathing and mechanical ventilation in rats.

Bruells CS, Maes K, Rossaint R, Thomas D, Cielen N, Bergs I, Bleilevens C, Weis J, Gayan-Ramirez G.

Anesthesiology. 2014 Mar;120(3):665-72. doi: 10.1097/ALN.0000000000000125.

PMID:
24401770
31.

Prolonged mechanical ventilation alters the expression pattern of angio-neogenetic factors in a pre-clinical rat model.

Bruells CS, Maes K, Rossaint R, Thomas D, Cielen N, Bleilevens C, Bergs I, Loetscher U, Dreier A, Gayan-Ramirez G, Behnke BJ, Weis J.

PLoS One. 2013 Aug 8;8(8):e70524. doi: 10.1371/journal.pone.0070524. eCollection 2013.

32.

Time course of diaphragm function recovery after controlled mechanical ventilation in rats.

Thomas D, Maes K, Agten A, Heunks L, Dekhuijzen R, Decramer M, Van Hees H, Gayan-Ramirez G.

J Appl Physiol (1985). 2013 Sep;115(6):775-84. doi: 10.1152/japplphysiol.00302.2012. Epub 2013 Jul 11.

33.

Ventilator-induced diaphragm dysfunction: time for (contr)action!

Gayan-Ramirez G.

Eur Respir J. 2013 Jul;42(1):12-5. doi: 10.1183/09031936.00076513. No abstract available.

34.

Greater diaphragm fatigability in individuals with recurrent low back pain.

Janssens L, Brumagne S, McConnell AK, Hermans G, Troosters T, Gayan-Ramirez G.

Respir Physiol Neurobiol. 2013 Aug 15;188(2):119-23. doi: 10.1016/j.resp.2013.05.028. Epub 2013 May 31.

PMID:
23727158
35.

Mechanisms of striated muscle dysfunction during acute exacerbations of COPD.

Gayan-Ramirez G, Decramer M.

J Appl Physiol (1985). 2013 May;114(9):1291-9. doi: 10.1152/japplphysiol.00847.2012. Epub 2013 Jan 31. Review.

36.

The assessment of inspiratory muscle fatigue in healthy individuals: a systematic review.

Janssens L, Brumagne S, McConnell AK, Raymaekers J, Goossens N, Gayan-Ramirez G, Hermans G, Troosters T.

Respir Med. 2013 Mar;107(3):331-46. doi: 10.1016/j.rmed.2012.11.019. Epub 2012 Dec 27. Review.

37.

Vitamin D supplementation during rehabilitation in COPD: a secondary analysis of a randomized trial.

Hornikx M, Van Remoortel H, Lehouck A, Mathieu C, Maes K, Gayan-Ramirez G, Decramer M, Troosters T, Janssens W.

Respir Res. 2012 Sep 25;13:84. doi: 10.1186/1465-9921-13-84.

38.

Bortezomib partially protects the rat diaphragm from ventilator-induced diaphragm dysfunction.

Agten A, Maes K, Thomas D, Cielen N, Van Hees HW, Dekhuijzen RP, Decramer M, Gayan-Ramirez G.

Crit Care Med. 2012 Aug;40(8):2449-55. doi: 10.1097/CCM.0b013e3182553a88.

PMID:
22809912
39.

Antielastin B-cell and T-cell immunity in patients with chronic obstructive pulmonary disease.

Rinaldi M, Lehouck A, Heulens N, Lavend'homme R, Carlier V, Saint-Remy JM, Decramer M, Gayan-Ramirez G, Janssens W.

Thorax. 2012 Aug;67(8):694-700. doi: 10.1136/thoraxjnl-2011-200690. Epub 2012 Mar 22.

PMID:
22442201
40.

Long-term nose-only cigarette smoke exposure induces emphysema and mild skeletal muscle dysfunction in mice.

Rinaldi M, Maes K, De Vleeschauwer S, Thomas D, Verbeken EK, Decramer M, Janssens W, Gayan-Ramirez GN.

Dis Model Mech. 2012 May;5(3):333-41. doi: 10.1242/dmm.008508. Epub 2012 Jan 25.

41.

High dose methylprednisolone counteracts the negative effects of rocuronium on diaphragm function.

Maes K, Testelmans D, Thomas D, Decramer M, Gayan-Ramirez G.

Intensive Care Med. 2011 Nov;37(11):1865-72. doi: 10.1007/s00134-011-2337-7. Epub 2011 Aug 18.

PMID:
21850533
42.

Repeated invasive lung function measurements in intubated mice: an approach for longitudinal lung research.

De Vleeschauwer SI, Rinaldi M, De Vooght V, Vanoirbeek JA, Vanaudenaerde BM, Verbeken EK, Decramer M, Gayan-Ramirez GN, Verleden GM, Janssens W.

Lab Anim. 2011 Apr;45(2):81-9. doi: 10.1258/la.2010.010111. Epub 2011 Feb 28.

PMID:
21357700
43.

N-Acetylcysteine protects the rat diaphragm from the decreased contractility associated with controlled mechanical ventilation.

Agten A, Maes K, Smuder A, Powers SK, Decramer M, Gayan-Ramirez G.

Crit Care Med. 2011 Apr;39(4):777-82. doi: 10.1097/CCM.0b013e318206cca9.

PMID:
21242791
44.

Corticosteroid effects on ventilator-induced diaphragm dysfunction in anesthetized rats depend on the dose administered.

Maes K, Agten A, Smuder A, Powers SK, Decramer M, Gayan-Ramirez G.

Respir Res. 2010 Dec 14;11:178. doi: 10.1186/1465-9921-11-178.

45.

Increased duration of mechanical ventilation is associated with decreased diaphragmatic force: a prospective observational study.

Hermans G, Agten A, Testelmans D, Decramer M, Gayan-Ramirez G.

Crit Care. 2010;14(4):R127. doi: 10.1186/cc9094. Epub 2010 Jul 1.

46.

Gene expression profiling in vastus lateralis muscle during an acute exacerbation of COPD.

Crul T, Testelmans D, Spruit MA, Troosters T, Gosselink R, Geeraerts I, Decramer M, Gayan-Ramirez G.

Cell Physiol Biochem. 2010;25(4-5):491-500. doi: 10.1159/000303054. Epub 2010 Mar 23.

47.

Resistance training prevents deterioration in quadriceps muscle function during acute exacerbations of chronic obstructive pulmonary disease.

Troosters T, Probst VS, Crul T, Pitta F, Gayan-Ramirez G, Decramer M, Gosselink R.

Am J Respir Crit Care Med. 2010 May 15;181(10):1072-7. doi: 10.1164/rccm.200908-1203OC. Epub 2010 Feb 4.

PMID:
20133927
48.

Atrophy and hypertrophy signalling in the diaphragm of patients with COPD.

Testelmans D, Crul T, Maes K, Agten A, Crombach M, Decramer M, Gayan-Ramirez G.

Eur Respir J. 2010 Mar;35(3):549-56. doi: 10.1183/09031936.00091108. Epub 2009 Aug 28.

49.

Noninvasive and invasive pulmonary function in mouse models of obstructive and restrictive respiratory diseases.

Vanoirbeek JA, Rinaldi M, De Vooght V, Haenen S, Bobic S, Gayan-Ramirez G, Hoet PH, Verbeken E, Decramer M, Nemery B, Janssens W.

Am J Respir Cell Mol Biol. 2010 Jan;42(1):96-104. doi: 10.1165/rcmb.2008-0487OC. Epub 2009 Apr 3.

PMID:
19346316
50.

Apocynin attenuates diaphragm oxidative stress and protease activation during prolonged mechanical ventilation.

McClung JM, Van Gammeren D, Whidden MA, Falk DJ, Kavazis AN, Hudson MB, Gayan-Ramirez G, Decramer M, DeRuisseau KC, Powers SK.

Crit Care Med. 2009 Apr;37(4):1373-9. doi: 10.1097/CCM.0b013e31819cef63.

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